Studies have not established the effect of spinach on breast cancer


Like beets and Swiss chard, spinach (Spinacia oleracea) belongs to the amaranth family. Spinach is a good dietary source of vitamin A, folate, and vitamin K, as well as iron, manganese and magnesium. Spinach contains various carotenoids such as beta-carotene and lutein, as well as a variety of lignans, chlorophylls, and glycolipids with suspected or demonstrated cancer fighting properties. Spinach has been shown to have anti-inflammatory, antioxidant, neuroprotective, and antimutagenic properties, and to protect the eyes from macular degeneration and cataracts. Spinach components have been shown to inhibit growth and proliferation of cervical cancer cells in the laboratory and carcinogen-induced colon cancer in mice. Dietary intake of spinach has been found to be associated with lower risks of head and neck, lung, gallbladder, stomach, liver, bladder, prostate and ovarian cancer in population studies.

Breast cancer-related effects of eating spinach

Carotenoids and glycolipids isolated from spinach have been demonstrated to cause dose-dependent growth inhibition in breast cancer cells. Several population studies have found that spinach consumption is associated with lower risk of breast cancer. Spinach consumption may help counteract the cancer-promoting effects of the heme iron in red meat.

Additional comments

Baby spinach has higher flavonoid concentration than mature spinach. Red spinach (Amaranthus gangeticus) is a plant used in South Asian cooking that is closely related to common spinach. Based on the few studies that have been performed, red spinach appears to have anti-cancer activities similar to that of common spinach.

Spinach is an abundant source of oxalate, which interferes with calcium absorption. Therefore spinach should not be eaten at the same time as calcium-rich foods by breast cancer patients and others to whom calcium levels are important. Oxalate can also contribute to calcium oxalate kidney stones in susceptible individuals. Preliminary evidence indicates that breast cells may accumulate oxalate and that it could promote the transformation of breast cells from normal to cancer cells. Boiling reduces the oxalate content of spinach and increases iron availability.

Non-organic spinach must be washed very thoroughly to remove pesticide residue as much as possible.

Below are links to recent studies concerning this food. For a more complete list, including less recent studies, please click on spinach.

Tags: , , , , , , ,

Selected breast cancer studies

Breast cancer resources | Definitions | Selected supplements and vitamins | Privacy policy | Search | Tags | Disclaimer/about us | Make a donation | Sitemap