Tag: lignan

News

03/11/18

Flaxseed lignans increase treatment effects of Adriamycin & Taxotere

06/03/17

Enterolactone reduces TN proliferation, migration and metastasis

11/02/16

Enterolactone increases radiation-induced breast cancer cell death

11/27/11

Women with high circulating enterolactone have better outcomes

09/15/11

High lignan intake may improve survival among women with ER- BC

02/27/11

Prediagnostic enterolactone levels linked to lower BC mortality

Foods

• • blackberries
  • buckwheat
  • flaxseed
  • sesame seeds and sesame oil

Studies

• Sesame Seeds: A Nutrient-Rich Superfood Cite
  Mostashari P, Mousavi Khaneghah A. Sesame Seeds: A Nutrient-Rich Superfood. Foods. MDPI AG; 2024; 13:1153 10.3390/foods13081153
• From dietary lignans to cancer therapy: Integrative systems analysis of enterolactone's molecular targets and signaling pathways in combatting cancer stem cells in triple-negative breast cancer Cite
  Mahajan A, Sharma N, Ulhe A, Patil R, Hegde M, Mali A. From dietary lignans to cancer therapy: Integrative systems analysis of enterolactone's molecular targets and signaling pathways in combatting cancer stem cells in triple-negative breast cancer. Food Bioscience. Elsevier BV; 2024; 58:103732 10.1016/j.fbio.2024.103732
• Cecal microbiota and mammary gland microRNA signatures are related and modifiable by dietary flaxseed with implications for breast cancer risk Cite
  Wu D, Thompson LU, Comelli EM. Cecal microbiota and mammary gland microRNA signatures are related and modifiable by dietary flaxseed with implications for breast cancer risk. Microbiology Spectrum. American Society for Microbiology; 2023; 10.1128/spectrum.02290-23
• Beyond Insoluble Dietary Fiber: Bioactive Compounds in Plant Foods Cite
  Timm M, Offringa LC, Van Klinken BJ, Slavin J. Beyond Insoluble Dietary Fiber: Bioactive Compounds in Plant Foods. Nutrients. MDPI AG; 2023; 15:4138 10.3390/nu15194138
• Proliferative response of ERα-positive breast cancer cells to 10 μM enterolactone, and the associated alteration in the transcriptomic landscape Cite
  Hatwik J, Patil HN, Limaye AM. Proliferative response of ERα-positive breast cancer cells to 10 μM enterolactone, and the associated alteration in the transcriptomic landscape. Gene. Elsevier BV; 2023;:147640 10.1016/j.gene.2023.147640
• A comprehensive review on nutraceutical potential of underutilized cereals and cereal-based products Cite
  Rawat M, Varshney A, Rai M, Chikara A, Pohty AL, Joshi A, et al. A comprehensive review on nutraceutical potential of underutilized cereals and cereal-based products. Journal of Agriculture and Food Research. Elsevier BV; 2023; 12:100619 10.1016/j.jafr.2023.100619
• Sesamin lacks zebrafish embryotoxicity but exhibits evidence of anti-angiogenesis, anti-oxidant and anti-inflammatory activities Cite
  Kitipaspallop W, Phuwapraisirisan P, Kim W, Chanchao C, Pimtong W. Sesamin lacks zebrafish embryotoxicity but exhibits evidence of anti-angiogenesis, anti-oxidant and anti-inflammatory activities. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. Elsevier BV; 2023; 269:109637 10.1016/j.cbpc.2023.109637
• The Biochemistry and Effectiveness of Antioxidants in Food, Fruits, and Marine Algae Cite
  Pruteanu LL, Bailey DS, Grădinaru AC, Jäntschi L. The Biochemistry and Effectiveness of Antioxidants in Food, Fruits, and Marine Algae. Antioxidants. MDPI AG; 2023; 12:860 10.3390/antiox12040860
• Anticancer potential of lignans from flaxseed: metabolites, molecular target, synthetic lignan, current challenges and perspectives Cite
  Mueed A, Deng Z, Korma SA, Shibli S, Jahangir M. Anticancer potential of lignans from flaxseed: metabolites, molecular target, synthetic lignan, current challenges and perspectives. Food & Function. Royal Society of Chemistry (RSC); 2023; 10.1039/d2fo02208g
• Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties Cite
  Zeeshan Bhatti M, Ismail H, Khan Kayani W. Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties. Secondary Metabolites - Trends and Reviews [Working Title]. IntechOpen; 2022; 10.5772/intechopen.103698
• Lignans: a versatile source of anticancer drugs Cite
  Mukhija M, Joshi BC, Bairy PS, Bhargava A, Sah AN. Lignans: a versatile source of anticancer drugs. Beni-Suef University Journal of Basic and Applied Sciences. Springer Science and Business Media LLC; 2022; 11 10.1186/s43088-022-00256-6
• Availability of bioactive flax lignan from foods and supplements Cite
  Tse TJ, Guo Y, Shim YY, Purdy SK, Kim JH, Cho JY, et al. Availability of bioactive flax lignan from foods and supplements. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2022;:1-16 10.1080/10408398.2022.2072807
• Habitual Phytoestrogen Intake is Associated with Breast Composition in Girls at 2 Years after Menarche Onset Cite
  Lesser C, Mericq V, Reyes M, GARMENDIA ML, Shepherd JA, Michels KB, et al. Habitual Phytoestrogen Intake is Associated with Breast Composition in Girls at 2 Years after Menarche Onset. Cancer Epidemiology, Biomarkers & Prevention. American Association for Cancer Research (AACR); 2022; 10.1158/1055-9965.epi-22-0016
• The secoisolariciresinol diglycoside (SDG) lignan content of oil flax: Genotypic and environmental variations and association with other traits Cite
  Zhang J, Xie Y, Miao C, Wang L, Zhao W, Li W, et al. The secoisolariciresinol diglycoside (SDG) lignan content of oil flax: Genotypic and environmental variations and association with other traits. Oil Crop Science. Elsevier BV; 2022; 10.1016/j.ocsci.2022.02.004
• Lignans of Sesame (Sesamum indicum L.): A Comprehensive Review Cite
  Andargie M, Vinas M, Rathgeb A, Möller E, Karlovsky P. Lignans of Sesame (Sesamum indicum L.): A Comprehensive Review. Molecules. MDPI AG; 2021; 26:883 10.3390/molecules26040883
• Antiestrogenic and antiproliferative potency of secoisolariciresinol diglucoside derivatives on MCF-7 breast cancer cells Cite
  Scherbakov AM, Stasevich OV, Salnikova DI, Andreeva OE, Mikhaevich EI. Antiestrogenic and antiproliferative potency of secoisolariciresinol diglucoside derivatives on MCF-7 breast cancer cells. Natural Product Research. Informa UK Limited; 2020;:1-7 10.1080/14786419.2020.1826479
• Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion? Cite
  Rodríguez-García C, Sánchez-Quesada C, Toledo E, Delgado-Rodríguez M, Gaforio J. Naturally Lignan-Rich Foods: A Dietary Tool for Health Promotion?. Molecules. MDPI AG; 2019; 24:917 10.3390/molecules24050917
• The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth Cite
  Bowers LW, Lineberger CG, Ford NA, Rossi EL, Punjala A, Camp KK, et al. The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2018; 173:545-557 10.1007/s10549-018-5021-6
• Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives Cite
  Basu P, Maier C. Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives. Biomedicine & Pharmacotherapy. Elsevier BV; 2018; 107:1648-1666 10.1016/j.biopha.2018.08.100
• Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers Cite
  Jaskulski S, Jung AY, Behrens S, Johnson T, Kaaks R, Thöne K, et al. Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers. International Journal of Cancer. Wiley; 2018; 143:2698-2708 10.1002/ijc.31647
• Pre-diagnostic plasma enterolactone concentrations and breast cancer prognosis among postmenopausal women – The Danish Diet, Cancer and Health cohort Cite
  Kyrø C, Hansen L, Frederiksen K, Nørskov NP, Bach Knudsen KE, Eriksen AK, et al. Pre-diagnostic plasma enterolactone concentrations and breast cancer prognosis among postmenopausal women – The Danish Diet, Cancer and Health cohort. Clinical Nutrition. Elsevier BV; 2018; 37:2217-2225 10.1016/j.clnu.2017.10.023
• Enterolactone concentrations and prognosis after postmenopausal breast cancer: Assessment of effect modification and meta-analysis Cite
  Seibold P, Vrieling A, Johnson TS, Buck K, Behrens S, Kaaks R, et al. Enterolactone concentrations and prognosis after postmenopausal breast cancer: Assessment of effect modification and meta-analysis. International Journal of Cancer. Wiley; 2014; 135:923-933 10.1002/ijc.28729
• Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3 Cite
  Di Y, De Silva F, Krol ES, Alcorn J. Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3. Nutrition and Cancer. Informa UK Limited; 2018; 70:306-315 10.1080/01635581.2018.1421677
• The Effect of Flaxseed in Breast Cancer: A Literature Review Cite
  Calado A, Neves PM, Santos T, Ravasco P. The Effect of Flaxseed in Breast Cancer: A Literature Review. Frontiers in Nutrition. Frontiers Media SA; 2018; 5 10.3389/fnut.2018.00004
• A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum) Cite
  Majdalawieh AF, Massri M, Nasrallah GK. A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum). European Journal of Pharmacology. Elsevier BV; 2017; 815:512-521 10.1016/j.ejphar.2017.10.020
• The Breast Cancer Resistance Protein (BCRP/ABCG2) influences the levels of enterolignans and their metabolites in plasma, milk and mammary gland Cite
  García-Mateos D, García-Villalba R, Marañón JA, Espín JC, Merino G, Álvarez AI. The Breast Cancer Resistance Protein (BCRP/ABCG2) influences the levels of enterolignans and their metabolites in plasma, milk and mammary gland. Journal of Functional Foods. Elsevier BV; 2017; 35:648-654 10.1016/j.jff.2017.06.038
• Association between Urinary Phytoestrogens and C-reactive Protein in the Continuous National Health and Nutrition Examination Survey Cite
  Reger MK, Zollinger TW, Liu Z, Jones J, Zhang J. Association between Urinary Phytoestrogens and C-reactive Protein in the Continuous National Health and Nutrition Examination Survey. Journal of the American College of Nutrition. Informa UK Limited; 2017; 36:434-441 10.1080/07315724.2017.1318722
• Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling Cite
  Mali A, Joshi A, Hegde M, Kadam S. Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling. Asian Pacific Journal of Cancer Prevention. Asian Pacific Organization for Cancer Prevention; 2017; 18 10.22034/APJCP.2017.18.4.905
• Antioxidant and antimicrobial activity of linseed lignans and phenolic acids Cite
  Kyselka J, Rabiej D, Dragoun M, Kreps F, Burčová Z, Němečková I, et al. Antioxidant and antimicrobial activity of linseed lignans and phenolic acids. European Food Research and Technology. Springer Science and Business Media LLC; 2017; 243:1633-1644 10.1007/s00217-017-2871-9
• Abstract P2-05-28: The impact of the plant lignin secoisolariciresinol diglycoside on preclinical models of estrogen receptor positive breast cancer Cite
  Bowers L, Ford N, Rossi E, Shamsunder M, Kimler B, Fabian C, et al. Abstract P2-05-28: The impact of the plant lignin secoisolariciresinol diglycoside on preclinical models of estrogen receptor positive breast cancer. Poster Session Abstracts. American Association for Cancer Research; 2016; 10.1158/1538-7445.sabcs15-p2-05-28
• Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer Cite
  Xiong X, Hu X, Li Y, Liu C. Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer. Nutrition and Cancer. Informa UK Limited; 2015; 67:1326-1334 10.1080/01635581.2015.1082113
• Age-dependency in the metabolism of flaxseed lignans by healthy adults Cite
  Edel AL, Pierce GN, Aliani M. Age-dependency in the metabolism of flaxseed lignans by healthy adults. Journal of Functional Foods. Elsevier BV; 2015; 17:948-957 10.1016/j.jff.2015.06.042
• Effects of Flaxseed Lignan Secoisolariciresinol Diglucosideon Preneoplastic Biomarkers of Cancer Progression in a Model of Simultaneous Breast and Ovarian Cancer Development Cite
  Delman DM, Fabian CJ, Kimler BF, Yeh H, Petroff BK. Effects of Flaxseed Lignan Secoisolariciresinol Diglucosideon Preneoplastic Biomarkers of Cancer Progression in a Model of Simultaneous Breast and Ovarian Cancer Development. Nutrition and Cancer. Informa UK Limited; 2015; 67:857-864 10.1080/01635581.2015.1042549
• Enterolactone concentrations and prognosis after postmenopausal breast cancer: Assessment of effect modification and meta-analysis Cite
  Seibold P, Vrieling A, Johnson TS, Buck K, Behrens S, Kaaks R, et al. Enterolactone concentrations and prognosis after postmenopausal breast cancer: Assessment of effect modification and meta-analysis. International Journal of Cancer. Wiley; 2014; 135:923-933 10.1002/ijc.28729
• Plasma enterolactone and breast cancer risk in the Nurses’ Health Study II Cite
  Xie J, Tworoger SS, Franke AA, Terry KL, Rice MS, Rosner BA, et al. Plasma enterolactone and breast cancer risk in the Nurses’ Health Study II. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 139:801-809 10.1007/s10549-013-2586-y
• Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk Cite
  Lowcock EC, Cotterchio M, Boucher BA. Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk. Cancer Causes & Control. Springer Science and Business Media LLC; 2013; 24:813-816 10.1007/s10552-013-0155-7
• Effect of different sample preparation methods on isoflavone, lignan, coumestan and flavonoid contents of various vegetables determined by triple quadrupole LC–MS/MS Cite
  Konar N, Poyrazoğlu ES, Demir K, Artik N. Effect of different sample preparation methods on isoflavone, lignan, coumestan and flavonoid contents of various vegetables determined by triple quadrupole LC–MS/MS. Journal of Food Composition and Analysis. Elsevier BV; 2012; 26:26-35 10.1016/j.jfca.2012.01.002
• Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention Cite
  Aiyer HS, Warri AM, Woode DR, Hilakivi-Clarke L, Clarke R. Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:5693-5708 10.1021/jf204084f
• Comparative Effects of Sesame Seed Lignan and Flaxseed Lignan in Reducing the Growth of Human Breast Tumors (MCF-7) at High Levels of Circulating Estrogen in Athymic Mice Cite
  Truan JS, Chen J, Thompson LU. Comparative Effects of Sesame Seed Lignan and Flaxseed Lignan in Reducing the Growth of Human Breast Tumors (MCF-7) at High Levels of Circulating Estrogen in Athymic Mice. Nutrition and Cancer. Informa UK Limited; 2012; 64:65-71 10.1080/01635581.2012.630165
• Dietary Intakes of Total and Specific Lignans Are Associated with Clinical Breast Tumor Characteristics Cite
  McCann SE, Hootman KC, Weaver AM, Thompson LU, Morrison C, Hwang H, et al. Dietary Intakes of Total and Specific Lignans Are Associated with Clinical Breast Tumor Characteristics. The Journal of Nutrition. Oxford University Press (OUP); 2011; 142:91-98 10.3945/jn.111.147264
• Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer Cite
  Mabrok HB, Klopfleisch R, Ghanem KZ, Clavel T, Blaut M, Loh G. Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer. Carcinogenesis. Oxford University Press (OUP); 2011; 33:203-208 10.1093/carcin/bgr256
• Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer Cite
  Buck K, Zaineddin AK, Vrieling A, Heinz J, Linseisen J, Flesch-Janys D, et al. Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2011; 105:1151-1157 10.1038/bjc.2011.374
• Serum Enterolactone and Prognosis of Postmenopausal Breast Cancer Cite
  Buck K, Vrieling A, Zaineddin AK, Becker S, Hüsing A, Kaaks R, et al. Serum Enterolactone and Prognosis of Postmenopausal Breast Cancer. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2011; 29:3730-3738 10.1200/jco.2011.34.6478
• Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status Cite
  Zaineddin AK, Vrieling A, Buck K, Becker S, Linseisen J, Flesch-Janys D, et al. Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status. International Journal of Cancer. Wiley; 2011; 130:1401-1410 10.1002/ijc.26157
• Prediagnostic plasma enterolactone levels and mortality among women with breast cancer Cite
  Olsen A, Christensen J, Knudsen KEB, Johnsen NF, Overvad K, Tjønneland A. Prediagnostic plasma enterolactone levels and mortality among women with breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2011; 128:883-889 10.1007/s10549-011-1397-2
• Reduction in Ki-67 in Benign Breast Tissue of High-Risk Women with the Lignan Secoisolariciresinol Diglycoside Cite
  Fabian CJ, Kimler BF, Zalles CM, Klemp JR, Petroff BK, Khan QJ, et al. Reduction in Ki-67 in Benign Breast Tissue of High-Risk Women with the Lignan Secoisolariciresinol Diglycoside. Cancer Prevention Research. American Association for Cancer Research (AACR); 2010; 3:1342-1350 10.1158/1940-6207.capr-10-0022
• Risk of needle tract seeding of breast cancer: cytological results derived from core wash material Cite
  Uematsu T, Kasami M. Risk of needle tract seeding of breast cancer: cytological results derived from core wash material. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2007; 110:51-55 10.1007/s10549-007-9685-6
• Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database Cite
  Ward HA, Kuhnle GG, Mulligan AA, Lentjes MA, Luben RN, Khaw K. Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database. American Journal of Clinical Nutrition. Oxford University Press (OUP); 2009; 91:440-448 10.3945/ajcn.2009.28282
• Phytoestrogen content of fruits and vegetables commonly consumed in the UK based on LC–MS and 13C-labelled standards Cite
  Kuhnle GG, Dell’Aquila C, Aspinall SM, Runswick SA, Joosen AM, Mulligan AA, et al. Phytoestrogen content of fruits and vegetables commonly consumed in the UK based on LC–MS and 13C-labelled standards. Food Chemistry. Elsevier BV; 2009; 116:542-554 10.1016/j.foodchem.2009.03.002
• Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis Cite
  KHAN G, PENTTINEN P, CABANES A, FOXWORTH A, CHEZEK A, MASTROPOLE K, et al. Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis. Reproductive Toxicology. Elsevier BV; 2007; 23:397-406 10.1016/j.reprotox.2007.02.002
• Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies Cite
  Velentzis LS, Cantwell MM, Cardwell C, Keshtgar MR, Leathem AJ, Woodside JV. Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies. British Journal of Cancer. Springer Science and Business Media LLC; 2009; 100:1492-1498 10.1038/sj.bjc.6605003
• Mammalian Lignan Formation in Rats Fed a Wheat Bran Diet Cite
  Nicolle C, Manach C, Morand C, Mazur W, Adlercreutz H, Rémésy C, et al. Mammalian Lignan Formation in Rats Fed a Wheat Bran Diet. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2002; 50:6222-6226 10.1021/jf020208z
• Dietary Lignan Intake and Postmenopausal Breast Cancer Risk by Estrogen and Progesterone Receptor Status Cite
  Touillaud MS, Thiebaut ACM, Fournier A, Niravong M, Boutron-Ruault M, Clavel-Chapelon F. Dietary Lignan Intake and Postmenopausal Breast Cancer Risk by Estrogen and Progesterone Receptor Status. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2007; 99:475-486 10.1093/jnci/djk096
• Dietary consumption of phytochemicals and breast cancer risk in Mexican women Cite
  Torres-Sanchez L, Galvan-Portillo M, Wolff MS, Lopez-Carrillo L. Dietary consumption of phytochemicals and breast cancer risk in Mexican women. Public Health Nutrition. Cambridge University Press (CUP); 2009; 12:825-831 10.1017/s136898000800325x
• Dietary phytoestrogen intake and premenopausal breast cancer risk in a German case-control study Cite
  Linseisen J, Piller R, Hermann S, Chang-Claude J. Dietary phytoestrogen intake and premenopausal breast cancer risk in a German case-control study. International Journal of Cancer. Wiley; 2004; 110:284-290 10.1002/ijc.20119
• Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women Cite
  Suzuki R, Rylander-Rudqvist T, Saji S, Bergkvist L, Adlercreutz H, Wolk A. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. British Journal of Cancer. Springer Science and Business Media LLC; 2008; 98:636-640 10.1038/sj.bjc.6604175
• Dietary Phytoestrogens Are Not Associated with Risk of Overall Breast Cancer But Diets Rich in Coumestrol Are Inversely Associated with Risk of Estrogen Receptor and Progesterone Receptor Negative Breast Tumors in Swedish Women Cite
  Hedelin M, Löf M, Olsson M, Adlercreutz H, Sandin S, Weiderpass E. Dietary Phytoestrogens Are Not Associated with Risk of Overall Breast Cancer But Diets Rich in Coumestrol Are Inversely Associated with Risk of Estrogen Receptor and Progesterone Receptor Negative Breast Tumors in Swedish Women. The Journal of Nutrition. Oxford University Press (OUP); 2008; 138:938-945 10.1093/jn/138.5.938
• Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2 Cite
  Menendez . Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: Relationship between the chemical structures of extra-virgin olive oil secoiridoids and lignans and their inhibitory activities on the tyrosine kinase activity of HER2. International Journal of Oncology. Spandidos Publications; 1992; 10.3892/ijo_00000127