Tag: genistein

Articles

• Supplements with warnings for breast cancer

News

05/27/20

Genistein promotes proliferation and metastasis in IBC animal model

04/08/16

Genistein could reduce treatment effects of Adriamycin in ER+/PR+ BC

09/14/14

Soy supplement promotes BC proliferation

04/24/12

Zinc plus resveratrol promotes mammary tumor development in rats

02/06/12

Soy supplements do not reduce breast cancer risk and could be harmful

01/18/12

High intake of soy isoflavones increases risk of HER2+ recurrence

12/06/11

Red clover compound biochanin A reduces potency of tamoxifen in rats

08/17/11

Genistein stimulates aromatase activity and ER+ BC cell growth

04/03/11

Soy protein may heighten risk of BC by influencing cell signaling

10/02/10

Soy protein isolate may increase PR expression & tumor aggressiveness

Foods

• • genistein and daidzein
  • soy protein isolate
  • soybean paste
  • soybeans
  • tofu

Studies

• Polyphenols Regulate the Activity of Endocrine-Disrupting Chemicals, Having Both Positive and Negative Effects Cite
  Leti Maggio E, Zucca C, Grande M, Carrano R, Infante A, Bei R, et al. Polyphenols Regulate the Activity of Endocrine-Disrupting Chemicals, Having Both Positive and Negative Effects. Journal of Xenobiotics. MDPI AG; 2024; 14:1378-1405 10.3390/jox14040077
• Equol: a metabolite of gut microbiota with potential antitumor effects Cite
  Lv J, Jin S, Zhang Y, Zhou Y, Li M, Feng N. Equol: a metabolite of gut microbiota with potential antitumor effects. Gut Pathogens. Springer Science and Business Media LLC; 2024; 16 10.1186/s13099-024-00625-9
• Effect of genistein supplementation on microenvironment regulation of breast tumors in obese mice Cite
  Jin S, Zheng Y, Li D, Liu X, Zhu T, Wang S, et al. Effect of genistein supplementation on microenvironment regulation of breast tumors in obese mice. Research Square Platform LLC; 2024; 10.21203/rs.3.rs-4497783/v1
• A combination of myokines and genistein suppresses cancer stemness in MCF-7 human breast cancer cells Cite
  Kwon H, Kim Y, Kim JH. A combination of myokines and genistein suppresses cancer stemness in MCF-7 human breast cancer cells. Nutrition Research and Practice. XMLink; 2024; 18:436 10.4162/nrp.2024.18.3.436
• Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors Cite
  Ravindra B. Malabadi , Sadiya MR , Kiran P. Kolkar , Simuzar S. Mammadova , Raju K. Chalannavar , Himansu Baijnath , et al. Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors. Open Access Research Journal of Biology and Pharmacy. Open Access Research Journals Publication; 2024; 10:028-071 10.53022/oarjbp.2024.10.2.0013
• Traditional and Domestic Cooking Dramatically Reduce Estrogenic Isoflavones in Soy-Foods Cite
  Bensaada S, Peruzzi G, Cubizolles L, Denayrolles M, Bennetau-Pelissero C. Traditional and Domestic Cooking Dramatically Reduce Estrogenic Isoflavones in Soy-Foods. MDPI AG; 2024; 10.20944/preprints202403.0708.v1
• Perspective: Observational studies involving low soy intake populations have limited ability for providing insight into the health effects of soybean isoflavones Cite
  Messina M, Messina V, Nagata C. Perspective: Observational studies involving low soy intake populations have limited ability for providing insight into the health effects of soybean isoflavones. Advances in Nutrition. Elsevier BV; 2024;:100210 10.1016/j.advnut.2024.100210
• Dietary Isoflavone Intake and Breast Cancer Prognosis: A Prospective Analysis and Meta-Analysis Cite
  Song S, Cheun J, Moon H, Noh D, Jung S, Lee ES, et al. Dietary Isoflavone Intake and Breast Cancer Prognosis: A Prospective Analysis and Meta-Analysis. Nutrition and Cancer. Informa UK Limited; 2023;:1-13 10.1080/01635581.2023.2279220
• Phytosterols activating nuclear receptors are involving in steroid hormone-dependent cancers: Myth or fact? Cite
  Bakrim S, El Omari N, Khan EJ, Khalid A, Abdalla AN, Chook JB, et al. Phytosterols activating nuclear receptors are involving in steroid hormone-dependent cancers: Myth or fact?. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 169:115783 10.1016/j.biopha.2023.115783
• Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer Cite
  da Silva FC, Brandão DC, Ferreira EA, Siqueira RP, Ferreira HSV, Da Silva Filho AA, et al. Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer. Pharmaceuticals. MDPI AG; 2023; 16:1466 10.3390/ph16101466
• Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling Cite
  Kubatka P, Koklesova L, Mazurakova A, Brockmueller A, Büsselberg D, Kello M, et al. Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling. Cancer and Metastasis Reviews. Springer Science and Business Media LLC; 2023; 10.1007/s10555-023-10134-x
• A Systematic Review on Chemical Actives from Plant Sources, Targets and Chemotherapy for Triple-Negative Breast Cancer Cite
  Varne AA, Bhatia MS, Ashtek SS. A Systematic Review on Chemical Actives from Plant Sources, Targets and Chemotherapy for Triple-Negative Breast Cancer. Pharmaceutical Chemistry Journal. Springer Science and Business Media LLC; 2023; 57:694-702 10.1007/s11094-023-02940-y
• Structure-Based Multi-Targeted Molecular Docking and Dynamic Simulation of Soybean-Derived Isoflavone Genistin as a Potential Breast Cancer Signaling Proteins Inhibitor Cite
  Elkhalifa AEO, Al-Shammari E, Kuddus M, Adnan M, Sachidanandan M, Awadelkareem AM, et al. Structure-Based Multi-Targeted Molecular Docking and Dynamic Simulation of Soybean-Derived Isoflavone Genistin as a Potential Breast Cancer Signaling Proteins Inhibitor. Life. MDPI AG; 2023; 13:1739 10.3390/life13081739
• Analysis of Safety Concerns on Herbal Products with Assumed Phytoestrogenic Activity Cite
  Tjeerdsma AM, van Hunsel FPAM, van de Koppel S, Ekhart C, Vitalone A, Woerdenbag HJ. Analysis of Safety Concerns on Herbal Products with Assumed Phytoestrogenic Activity. Pharmaceuticals. MDPI AG; 2023; 16:1137 10.3390/ph16081137
• Phytochemicals Modify the Action of Cancer Cells Mitochondrial Drug-Resistance Mechanism Cite
  Das S. Phytochemicals Modify the Action of Cancer Cells Mitochondrial Drug-Resistance Mechanism. Sciences of Pharmacy. Etflin; 2023; 2:79-105 10.58920/sciphar02030079
• The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC) Cite
  Farghadani R, Naidu R. The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC). Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 165:115170 10.1016/j.biopha.2023.115170
• In Vitro Effects of Combining Genistein with Aromatase Inhibitors: Concerns Regarding Its Consumption during Breast Cancer Treatment Cite
  Bezerra PHA, Amaral C, Almeida CF, Correia-da-Silva G, Torqueti MR, Teixeira N. In Vitro Effects of Combining Genistein with Aromatase Inhibitors: Concerns Regarding Its Consumption during Breast Cancer Treatment. Molecules. MDPI AG; 2023; 28:4893 10.3390/molecules28134893
• Insights on the Role of Polyphenols in Combating Cancer Drug Resistance Cite
  Farhan M. Insights on the Role of Polyphenols in Combating Cancer Drug Resistance. Biomedicines. MDPI AG; 2023; 11:1709 10.3390/biomedicines11061709
• The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer Cite
  Pejčić T, Zeković M, Bumbaširević U, Kalaba M, Vovk I, Bensa M, et al. The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer. Antioxidants. MDPI AG; 2023; 12:368 10.3390/antiox12020368
• Understanding the phytoestrogen genistein actions on breast cancer: Insights on estrogen receptor equivalence, pleiotropic essence and emerging paradigms in bioavailability modulation Cite
  Mukherjee TK, Malik P, Singh R, Kumar M, Malik A. Understanding the phytoestrogen genistein actions on breast cancer: Insights on estrogen receptor equivalence, pleiotropic essence and emerging paradigms in bioavailability modulation. Current Topics in Medicinal Chemistry. Bentham Science Publishers Ltd.; 2023; 23 10.2174/1568026623666230103163023
• Soy Isoflavones Induce Feminization of Japanese Eel (Anguilla japonica) Cite
  Inaba H, Iwata Y, Suzuki T, Horiuchi M, Surugaya R, Ijiri S, et al. Soy Isoflavones Induce Feminization of Japanese Eel (Anguilla japonica). International Journal of Molecular Sciences. MDPI AG; 2022; 24:396 10.3390/ijms24010396
• Soy isoflavones decrease fibroglandular breast tissue measured by magnetic resonance imaging in premenopausal women: a 2-year randomized double-blind placebo controlled clinical trial Cite
  Lu LW, Chen N, Brunder DG, Nayeem F, Nagamani M, Nishino TK, et al. Soy isoflavones decrease fibroglandular breast tissue measured by magnetic resonance imaging in premenopausal women: a 2-year randomized double-blind placebo controlled clinical trial. Clinical Nutrition ESPEN. Elsevier BV; 2022; 10.1016/j.clnesp.2022.10.007
• Estrogenic in vitro evaluation of zearalenone and its phase I and II metabolites in combination with soy isoflavones Cite
  Grgic D, Betschler A, Früholz R, Novak B, Varga E, Marko D. Estrogenic in vitro evaluation of zearalenone and its phase I and II metabolites in combination with soy isoflavones. Archives of Toxicology. Springer Science and Business Media LLC; 2022; 10.1007/s00204-022-03358-3
• Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties Cite
  Zeeshan Bhatti M, Ismail H, Khan Kayani W. Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties. Secondary Metabolites - Trends and Reviews [Working Title]. IntechOpen; 2022; 10.5772/intechopen.103698
• Isoflavones in Soybean as a Daily Nutrient: The Mechanisms of Action and How They Alter the Pharmacokinetics of Drugs Cite
  SOYATA A, HASANAH AN, RUSDIANA T. Isoflavones in Soybean as a Daily Nutrient: The Mechanisms of Action and How They Alter the Pharmacokinetics of Drugs. Turkish Journal of Pharmaceutical Sciences. Galenos Yayinevi; 2021; 18:799-810 10.4274/tjps.galenos.2020.79106
• Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics Cite
  Meerson A, Khatib S, Mahajna J. Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics. International Journal of Molecular Sciences. MDPI AG; 2021; 22:13044 10.3390/ijms222313044
• Isoflavones in Animals: Metabolism and Effects in Livestock and Occurrence in Feed Cite
  Grgic D, Varga E, Novak B, Müller A, Marko D. Isoflavones in Animals: Metabolism and Effects in Livestock and Occurrence in Feed. Toxins. MDPI AG; 2021; 13:836 10.3390/toxins13120836
• Genistein Interferes with Antitumor Effects of Cisplatin in an Ovariectomized Breast Cancer Xenograft Tumor Model Cite
  Ma X, Yu X, Min J, Chen X, Liu R, Cui X, et al. Genistein Interferes with Antitumor Effects of Cisplatin in an Ovariectomized Breast Cancer Xenograft Tumor Model. Toxicology Letters. Elsevier BV; 2021; 10.1016/j.toxlet.2021.11.013
• Developmental exposure to phytoestrogens found in soy: New findings and clinical implications Cite
  Suen AA, Kenan AC, Williams CJ. Developmental exposure to phytoestrogens found in soy: New findings and clinical implications. Biochemical Pharmacology. Elsevier BV; 2021;:114848 10.1016/j.bcp.2021.114848
• Therapeutic Effects of Dietary Soybean Genistein on Triple-Negative Breast Cancer via Regulation of Epigenetic Mechanisms Cite
  Sharma M, Arora I, Chen M, Wu H, Crowley MR, Tollefsbol TO, et al. Therapeutic Effects of Dietary Soybean Genistein on Triple-Negative Breast Cancer via Regulation of Epigenetic Mechanisms. Nutrients. MDPI AG; 2021; 13:3944 10.3390/nu13113944
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Endocrine disruptors on and in fruits and vegetables: estimation of the potential exposure of the French population Cite
  Lee A, Bensaada S, Lamothe V, Lacoste M, Bennetau-Pelissero C. Endocrine disruptors on and in fruits and vegetables: estimation of the potential exposure of the French population. Food Chemistry. Elsevier BV; 2021;:131513 10.1016/j.foodchem.2021.131513
• Elucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells Cite
  Flasch M, Bueschl C, Del Favero G, Adam G, Schuhmacher R, Marko D, et al. Elucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells. Environment International. Elsevier BV; 2022; 158:106940 10.1016/j.envint.2021.106940
• Role of Phytochemicals in Cancer Chemoprevention: Insights Cite
  George BP, Chandran R, Abrahamse H. Role of Phytochemicals in Cancer Chemoprevention: Insights. Antioxidants. MDPI AG; 2021; 10:1455 10.3390/antiox10091455
• Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis Cite
  Maroni P, Bendinelli P, Fulgenzi A, Ferraretto A. Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis. Biomolecules. MDPI AG; 2021; 11:1336 10.3390/biom11091336
• Impact of feeding modified soy protein concentrate in the starter phase on growth performance and gastrointestinal responses in broiler chickens through to day 42 of age Cite
  Kiarie EG, Mohammadigheisar M, Kakhki RAM, Madsen MH. Impact of feeding modified soy protein concentrate in the starter phase on growth performance and gastrointestinal responses in broiler chickens through to day 42 of age. Poultry Science. Elsevier BV; 2021; 100:101147 10.1016/j.psj.2021.101147
• Isoflavones alter male and female fertility in different development windows Cite
  Sleiman HK, de Oliveira JM, Langoni de Freitas GB. Isoflavones alter male and female fertility in different development windows. Biomedicine & Pharmacotherapy. Elsevier BV; 2021; 140:111448 10.1016/j.biopha.2021.111448
• Therapeutic effects of polyphenols in fermented soybean and black soybean products Cite
  Khosravi A, Razavi SH. Therapeutic effects of polyphenols in fermented soybean and black soybean products. Journal of Functional Foods; 2021; 81:104467 https://doi.org/10.1016/j.jff.2021.104467
• Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line Cite
  Kollareddy M, Martinez LA. Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line. Cells. MDPI AG; 2021; 10:797 10.3390/cells10040797
• Screening of Novel Source for Genistein by Rapid and Sensitive UPLC-APCI-TOF Mass Spectrometry Cite
  Bettaiah A, Prabhushankar HB. Screening of Novel Source for Genistein by Rapid and Sensitive UPLC-APCI-TOF Mass Spectrometry. International Journal of Food Science. Hindawi Limited; 2021; 2021:1-12 10.1155/2021/5537917
• Effects of Chronic Dietary Exposure to Phytoestrogen Genistein on Uterine Morphology in Mice Cite
  B. Arcanjo R, Richardson KA, Yang S, Patel S, Flaws JA, Nowak RA. Effects of Chronic Dietary Exposure to Phytoestrogen Genistein on Uterine Morphology in Mice. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2021; 69:1693-1704 10.1021/acs.jafc.0c07456
• Serum isoflavones and lignans and odds of breast cancer in pre- and postmenopausal Chinese women Cite
  Feng X, Ho SC, Zhan X, Zuo L, Mo X, Zhang X, et al. Serum isoflavones and lignans and odds of breast cancer in pre- and postmenopausal Chinese women. Menopause. Ovid Technologies (Wolters Kluwer Health); 2021; Publish Ahead of Print 10.1097/gme.0000000000001715
• From Proteomics to Personalized Medicine: The Importance of Isoflavone Dose and Estrogen Receptor Status in Breast Cancer Cells Cite
  Ilieș M, Uifălean A, Pașca S, Dhople VM, Lalk M, Iuga CA, et al. From Proteomics to Personalized Medicine: The Importance of Isoflavone Dose and Estrogen Receptor Status in Breast Cancer Cells. Journal of Personalized Medicine. MDPI AG; 2020; 10:292 10.3390/jpm10040292
• Metabolomic and Transcriptomic Analysis of MCF-7 Cells Exposed to 23 Chemicals at Human-Relevant Levels: Estimation of Individual Chemical Contribution to Effects Cite
  Liu M, Jia S, Dong T, Zhao F, Xu T, Yang Q, et al. Metabolomic and Transcriptomic Analysis of MCF-7 Cells Exposed to 23 Chemicals at Human-Relevant Levels: Estimation of Individual Chemical Contribution to Effects. Environmental Health Perspectives. Environmental Health Perspectives; 2020; 128:127008 10.1289/ehp6641
• Isoflavone intake on the risk of overall breast cancer and molecular subtypes in women at high risk for hereditary breast cancer Cite
  Sim EJ, Ko K, Ahn C, Park SM, Surh Y, An S, et al. Isoflavone intake on the risk of overall breast cancer and molecular subtypes in women at high risk for hereditary breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 184:615-626 10.1007/s10549-020-05875-0
• Neonatal exposure to genistein affects reproductive physiology and behavior in female and male Long-Evans rats Cite
  Ali M, Broyles TM, Davis LK, Gonzalez CM, Lucero D, Stary L, et al. Neonatal exposure to genistein affects reproductive physiology and behavior in female and male Long-Evans rats. Behavioural Pharmacology. Ovid Technologies (Wolters Kluwer Health); 2020; 31:610-621 10.1097/fbp.0000000000000569
• Abstract 2440: The epigenetic influence of maternal diet on prevention of high-fat diet induced obesity and breast cancer in later life Cite
  Li Y, Chen M, Tollefsbol T. Abstract 2440: The epigenetic influence of maternal diet on prevention of high-fat diet induced obesity and breast cancer in later life. Molecular and Cellular Biology / Genetics. American Association for Cancer Research; 2020; 10.1158/1538-7445.am2020-2440
• Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms Cite
  Bhosale PB, Ha SE, Vetrivel P, Kim HH, Kim J, Park K, et al. Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms. Journal of Biomedical Translational Research. Research Institute of Veterinary Medicine; 2020; 21:50-58 10.12729/jbtr.2020.21.2.050
• Flavonoids in Cancer Metastasis Cite
  Liskova A, Koklesova L, Samec M, Smejkal K, Samuel SM, Varghese E, et al. Flavonoids in Cancer Metastasis. Cancers. MDPI AG; 2020; 12:1498 10.3390/cancers12061498
• Dietary Intake and Plasma Levels of Isoflavones Among Breast Cancer Survivors Cite
  Song S, Moon H, Noh D, Jung S, Lee ES, Kim Z, et al. Dietary Intake and Plasma Levels of Isoflavones Among Breast Cancer Survivors. Current Developments in Nutrition. Oxford University Press (OUP); 2020; 4:1490-1490 10.1093/cdn/nzaa061_118
• Changes in steroid hormone profile and tumour progression after genistein treatment of canine inflammatory mammary cancer xenotransplanted mice Cite
  Martín-Ruiz A, Peña L, González-Gil A, Silvan G, Caceres S, Illera J. Changes in steroid hormone profile and tumour progression after genistein treatment of canine inflammatory mammary cancer xenotransplanted mice. Research in Veterinary Science. Elsevier BV; 2020; 131:87-91 10.1016/j.rvsc.2020.04.013
• Genistein improves the reproductive performance and bone status of breeder hens during the late egg-laying period Cite
  Lv Z, Yan S, Li G, Liu D, Guo Y. Genistein improves the reproductive performance and bone status of breeder hens during the late egg-laying period. Poultry Science. Elsevier BV; 2019; 98:7022-7029 10.3382/ps/pez367
• (±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth Cite
  Song H, Hughes JR, Turner RT, Iwaniec UT, Doerge DR, Helferich WG. (±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth. Food and Chemical Toxicology. Elsevier BV; 2020; 136:110979 10.1016/j.fct.2019.110979
• Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer Cite
  Jaskulski S, Jung AY, Huebner M, Poschet G, Hell R, Hüsing A, et al. Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer. Nutrition and Cancer. Informa UK Limited; 2019; 72:1155-1169 10.1080/01635581.2019.1672762
• Rodent Models Assessing Mammary Tumor Prevention by Soy or Soy Isoflavones Cite
  Moorehead . Rodent Models Assessing Mammary Tumor Prevention by Soy or Soy Isoflavones. Genes. MDPI AG; 2019; 10:566 10.3390/genes10080566
• Breast Cancer and Dietary Intake of Endocrine Disruptors: a Review of Recent Literature Cite
  Bowes DA, Halden RU. Breast Cancer and Dietary Intake of Endocrine Disruptors: a Review of Recent Literature. Current Pathobiology Reports. Springer Science and Business Media LLC; 2019; 7:41-46 10.1007/s40139-019-00199-1
• Use of dietary supplements containing soy isoflavones and breast cancer risk among women aged >50 y: a prospective study Cite
  Touillaud M, Gelot A, Mesrine S, Bennetau-Pelissero C, Clavel-Chapelon F, Arveux P, et al. Use of dietary supplements containing soy isoflavones and breast cancer risk among women aged >50 y: a prospective study. The American Journal of Clinical Nutrition. Oxford University Press (OUP); 2019; 109:597-605 10.1093/ajcn/nqy313
• Individual factors define the overall effects of dietary genistein exposure on breast cancer patients Cite
  Liu R, Yu X, Chen X, Zhong H, Liang C, Xu X, et al. Individual factors define the overall effects of dietary genistein exposure on breast cancer patients. Nutrition Research. Elsevier BV; 2019; 67:1-16 10.1016/j.nutres.2019.03.015
• ERβ modulates genistein’s cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway Cite
  Liu R, Xu X, Liang C, Chen X, Yu X, Zhong H, et al. ERβ modulates genistein’s cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2019; 456:205-216 10.1007/s11010-019-03505-y
• The association of urinary estrogen levels with urinary isoflavone levels: Difference between premenopausal women and postmenopausal women Cite
  Yasui T, Ideno Y, Onizuka Y, Nakajima-Shimada J, Lee J, Shinozaki H, et al. The association of urinary estrogen levels with urinary isoflavone levels: Difference between premenopausal women and postmenopausal women. Maturitas. Elsevier BV; 2019; 121:41-47 10.1016/j.maturitas.2018.12.010
• Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives Cite
  Basu P, Maier C. Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives. Biomedicine & Pharmacotherapy. Elsevier BV; 2018; 107:1648-1666 10.1016/j.biopha.2018.08.100
• Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation Cite
  Hüser S, Guth S, Joost HG, Soukup ST, Köhrle J, Kreienbrock L, et al. Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation. Archives of Toxicology. Springer Science and Business Media LLC; 2018; 92:2703-2748 10.1007/s00204-018-2279-8
• Use of dietary supplements in soy isoflavones and risk of breast cancer among women aged over 50 years: Results from the E3 N prospective cohort Cite
  Fournier A, Touillaud M, Gelot A, Mesrine S, Bennetau-Pelissero C, Boutron-Ruault M. Use of dietary supplements in soy isoflavones and risk of breast cancer among women aged over 50 years: Results from the E3 N prospective cohort. Revue d'Épidémiologie et de Santé Publique. Elsevier BV; 2018; 66:S285 10.1016/j.respe.2018.05.129
• Synergistic Effect of Bioactive Anticarcinogens from Soybean on Anti-Proliferative Activity in MDA-MB-231 and MCF-7 Human Breast Cancer Cells In Vitro Cite
  Zhu Y, Yao Y, Shi Z, Everaert N, Ren G. Synergistic Effect of Bioactive Anticarcinogens from Soybean on Anti-Proliferative Activity in MDA-MB-231 and MCF-7 Human Breast Cancer Cells In Vitro. Molecules. MDPI AG; 2018; 23:1557 10.3390/molecules23071557
• Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition Cite
  Paul B, Royston KJ, Li Y, Stoll ML, Skibola CF, Wilson LS, et al. Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition. PLOS ONE. Public Library of Science (PLoS); 2017; 12:e0189756 10.1371/journal.pone.0189756
• Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy Cite
  Warth B, Raffeiner P, Granados A, Huan T, Fang M, Forsberg EM, et al. Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy. Cell Chemical Biology. Elsevier BV; 2018; 25:291-300.e3 10.1016/j.chembiol.2017.12.010
• Equol Enhances Apoptosis-inducing Activity of Genistein by Increasing Bax/Bcl-xL Expression Ratio in MCF-7 Human Breast Cancer Cells Cite
  Ono M, Ejima K, Higuchi T, Takeshima M, Wakimoto R, Nakano S. Equol Enhances Apoptosis-inducing Activity of Genistein by Increasing Bax/Bcl-xL Expression Ratio in MCF-7 Human Breast Cancer Cells. Nutrition and Cancer. Informa UK Limited; 2017; 69:1300-1307 10.1080/01635581.2017.1367945
• The Impacts of Genistein and Daidzein on Estrogen Conjugations in Human Breast Cancer Cells: A Targeted Metabolomics Approach Cite
  Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Pachmann B, et al. The Impacts of Genistein and Daidzein on Estrogen Conjugations in Human Breast Cancer Cells: A Targeted Metabolomics Approach. Frontiers in Pharmacology. Frontiers Media SA; 2017; 8 10.3389/fphar.2017.00699
• DNA Methylation Targets Influenced by Bisphenol A and/or Genistein Are Associated with Survival Outcomes in Breast Cancer Patients Cite
  Jadhav R, Santucci-Pereira J, Wang Y, Liu J, Nguyen T, Wang J, et al. DNA Methylation Targets Influenced by Bisphenol A and/or Genistein Are Associated with Survival Outcomes in Breast Cancer Patients. Genes. MDPI AG; 2017; 8:144 10.3390/genes8050144
• Dietary Isoflavones and Breast Cancer Risk Cite
  Ziaei S, Halaby R. Dietary Isoflavones and Breast Cancer Risk. Medicines. MDPI AG; 2017; 4:18 10.3390/medicines4020018
• Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry Cite
  Zhang FF, Haslam DE, Terry MB, Knight JA, Andrulis IL, Daly MB, et al. Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry. Cancer. Wiley; 2017; 123:2070-2079 10.1002/cncr.30615
• Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats Cite
  Zhang X, Cook KL, Warri A, Cruz IM, Rosim M, Riskin J, et al. Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats. Clinical Cancer Research. American Association for Cancer Research (AACR); 2017; 23:814-824 10.1158/1078-0432.ccr-16-1735
• Combinatory estrogenic effects between the isoflavone genistein and the mycotoxins zearalenone and alternariol in vitro Cite
  Vejdovszky K, Schmidt V, Warth B, Marko D. Combinatory estrogenic effects between the isoflavone genistein and the mycotoxins zearalenone and alternariol in vitro. Molecular Nutrition & Food Research. Wiley; 2016; 61:1600526 10.1002/mnfr.201600526
• Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells Cite
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