Tag: hotPepper

Articles

• Chemo brain symptoms and outcomes
• Foods to eat and avoid during tamoxifen treatment
• Foods to eat and avoid for ER+/PR- patients and survivors
• Foods to eat and avoid for inflammatory breast cancer (IBC)
• Foods to eat and avoid for lobular breast cancer patients & survivors
• The Mediterranean diet is a good starting point for breast cancer
• The raw food diet is not ideal for breast cancer

News

07/20/25

Capsaicin increases doxorubicin toxicity in mouse model of triple negative BC

04/20/25

Capsanthin inhibits triple negative breast cancer brain metastasis

01/12/18

Hot pepper compound capsaicin reduces tumor development

01/08/12

Italian women with high vegetable consumption have lower BC risk

Foods

• • hot peppers

Studies

• Influence of fruit maturation on phytochemical profiles and antidiabetic potential in peppers Cite
  Afshari M, Sadeghi M, Lee S. Influence of fruit maturation on phytochemical profiles and antidiabetic potential in peppers. Food Bioscience. Elsevier BV; 2025;:106645 10.1016/j.fbio.2025.106645
• Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment Cite
  Nguyen MH, Nguyen TYN, Le THN, Le TNT, Chau NTN, Le TMH, et al. Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment. Heliyon. Elsevier BV; 2024; 10:e39229 10.1016/j.heliyon.2024.e39229
• Capsaicinoids and cytotoxic activity in Capsicum annuum var. conoides Cite
  Su Y, Zhang Y, Li Q, Wang J, Shao Y, Yu H, et al. Capsaicinoids and cytotoxic activity in Capsicum annuum var. conoides. Journal of Molecular Structure. Elsevier BV; 2024; 1322:140326 10.1016/j.molstruc.2024.140326
• Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder Cite
  Deng R, Yu S, Ruan X, Liu H, Zong G, Cheng P, et al. Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder. Cell Communication and Signaling. Springer Science and Business Media LLC; 2023; 21 10.1186/s12964-023-01265-3
• Evaluating CNN Models and Optimization Techniques for Quality Classification of Dried Chili Peppers (Capsicum annuum L.) Cite
  Lopez-Betancur D, Saucedo-Anaya T, Guerrero-Mendez C, Navarro-Solís D, Silva-Acosta L, Robles-Guerrero A, et al. Evaluating CNN Models and Optimization Techniques for Quality Classification of Dried Chili Peppers (Capsicum annuum L.). International Journal of Combinatorial Optimization Problems and Informatics. Editorial Académica Dragón Azteca; 2024; 15:13-25 10.61467/2007.1558.2024.v15i2.462
• Anthocyanins from pomegranate peel (Punica granatum), chili pepper fruit (Capsicum annuum), and bougainvillea flowers (Bougainvillea spectabilis) with multiple biofunctions: Antibacterial, antioxidant, and anticancer Cite
  Abdelrahman KN, Abdel Ghany AGA, Saber RA, Osman A, Sitohy B, Sitohy M. Anthocyanins from pomegranate peel (Punica granatum), chili pepper fruit (Capsicum annuum), and bougainvillea flowers (Bougainvillea spectabilis) with multiple biofunctions: Antibacterial, antioxidant, and anticancer. Heliyon. Elsevier BV; 2024; 10:e32222 10.1016/j.heliyon.2024.e32222
• Capsaicin ameliorates chemotherapy response via cancer hallmarks modulation: an overview of its synergic potential Cite
  Costa RF, Cadoná FC. Capsaicin ameliorates chemotherapy response via cancer hallmarks modulation: an overview of its synergic potential. Journal of Herbal Medicine. Elsevier BV; 2024;:100882 10.1016/j.hermed.2024.100882
• Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy Cite
  Khan F, Pandey P, Verma M, Ramniwas S, Lee D, Moon S, et al. Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy. Biomedicine & Pharmacotherapy. Elsevier BV; 2024; 173:116363 10.1016/j.biopha.2024.116363
• Chili pepper extracts, capsaicin, and dihydrocapsaicin as potential anticancer agents targeting topoisomerases Cite
  Hudáková T, Šemeláková M, Očenáš P, Kožurková M, Krochtová K, Sovová S, et al. Chili pepper extracts, capsaicin, and dihydrocapsaicin as potential anticancer agents targeting topoisomerases. BMC Complementary Medicine and Therapies. Springer Science and Business Media LLC; 2024; 24 10.1186/s12906-024-04394-5
• Anticancer Activity of Region B Capsaicin Analogs Cite
  Brown KC, Modi KJ, Light RS, Cox AJ, Long TE, Gadepalli RS, et al. Anticancer Activity of Region B Capsaicin Analogs. Journal of Medicinal Chemistry. American Chemical Society (ACS); 2023; 10.1021/acs.jmedchem.2c01594
• Capsanthin-Loaded Micelles: Preparation, Characterization and in vitro Evaluation of Cytotoxicity Using MDA-MB-231 Breast Cancer Cell Line Cite
  Shanmugham V, Subban R. Capsanthin-Loaded Micelles: Preparation, Characterization and in vitro Evaluation of Cytotoxicity Using MDA-MB-231 Breast Cancer Cell Line. Food Technology and Biotechnology. Faculty of Food Technology and Biotechnology - University of Zagreb; 2022; 60:350-360 10.17113/ftb.60.03.22.7405
• Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer Cite
  Adetunji TL, Olawale F, Olisah C, Adetunji AE, Aremu AO. Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer. Frontiers in Oncology. Frontiers Media SA; 2022; 12 10.3389/fonc.2022.908487
• Fate of Bioactive Compounds during Lactic Acid Fermentation of Fruits and Vegetables Cite
  Paramithiotis S, Das G, Shin H, Patra JK. Fate of Bioactive Compounds during Lactic Acid Fermentation of Fruits and Vegetables. Foods. MDPI AG; 2022; 11:733 10.3390/foods11050733
• Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms Cite
  Slika H, Mansour H, Wehbe N, Nasser SA, Iratni R, Nasrallah G, et al. Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 146:112442 10.1016/j.biopha.2021.112442
• Effect of capsaicin on breast cancer resistance protein (Bcrp/Abcg2) and pharmacokinetics of probe substrates in rats Cite
  Chen F, Wang L, Zhai X, Wang N, Qin Y, Zhu C, et al. Effect of capsaicin on breast cancer resistance protein (Bcrp/Abcg2) and pharmacokinetics of probe substrates in rats. Xenobiotica. Informa UK Limited; 2022;:1-15 10.1080/00498254.2021.2025281
• Cytotoxic Effect of Capsicum annum L. extract on T47D Cells: In vitro Study Cite
  Kurnijasanti R, Fadholly A. Cytotoxic Effect of Capsicum annum L. extract on T47D Cells: In vitro Study. Research Journal of Pharmacy and Technology. A and V Publications; 2021;:3389-3392 10.52711/0974-360x.2021.00589
• Capsaicin suppresses breast cancer cell viability by regulating the CDK8/PI3K/Akt/Wnt/β‑catenin signaling pathway Cite
  Wu D, Jia H, Zhang Z, Li S. Capsaicin suppresses breast cancer cell viability by regulating the CDK8/PI3K/Akt/Wnt/β‑catenin signaling pathway. Molecular Medicine Reports. Spandidos Publications; 2020; 22:4868-4876 10.3892/mmr.2020.11585
• Carotenoids of Capsicum Fruits: Pigment Profile and Health-Promoting Functional Attributes Cite
  Mohd Hassan N, Yusof NA, Yahaya AF, Mohd Rozali NN, Othman R. Carotenoids of Capsicum Fruits: Pigment Profile and Health-Promoting Functional Attributes. Antioxidants. MDPI AG; 2019; 8:469 10.3390/antiox8100469
• Influence of Capsaicinoids Content on the Microbial Community during Kimchi Fermentation Cite
  Park B, Yang J, Moon EW, Seo H, Ha J. Influence of Capsaicinoids Content on the Microbial Community during Kimchi Fermentation. Journal of Microbiology and Biotechnology. Korean Society for Microbiology and Biotechnology; 2019; 29:1580-1590 10.4014/jmb.1907.07023
• Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin Cite
  Li H, Krstin S, Wang S, Wink M. Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin. Molecules. MDPI AG; 2018; 23:557 10.3390/molecules23030557
• The Impact of Capsaicin Intake on Risk of Developing Gastric Cancers: A Meta-Analysis Cite
  Pabalan N, Jarjanazi H, Ozcelik H. The Impact of Capsaicin Intake on Risk of Developing Gastric Cancers: A Meta-Analysis. Journal of Gastrointestinal Cancer. Springer Science and Business Media LLC; 2014; 45:334-341 10.1007/s12029-014-9610-2
• Suppressive effects of capsaicin against N-nitrosomethylurea-induced mammary tumorigenesis in rats Cite
  El-kott AF, Bin-Meferij MM. Suppressive effects of capsaicin against N-nitrosomethylurea-induced mammary tumorigenesis in rats. Biomedicine & Pharmacotherapy. Elsevier BV; 2018; 98:673-679 10.1016/j.biopha.2017.12.036
• High Spicy Food Intake and Risk of Cancer Cite
  Chen Y, Zou X, Zheng T, Zhou Q, Qiu H, Chen Y, et al. High Spicy Food Intake and Risk of Cancer. Chinese Medical Journal. Ovid Technologies (Wolters Kluwer Health); 2017; 130:2241-2250 10.4103/0366-6999.213968
• Capsaicinoids are silent estrogens, a class of estrogenic chemicals without cell-proliferation activity Cite
  Zhu Y, Kiyama R. Capsaicinoids are silent estrogens, a class of estrogenic chemicals without cell-proliferation activity. Environmental Technology & Innovation. Elsevier BV; 2017; 7:182-193 10.1016/j.eti.2017.02.006
• Reactivation of mutant p53 by capsaicin, the major constituent of peppers Cite
  Garufi A, Pistritto G, Cirone M, D’Orazi G. Reactivation of mutant p53 by capsaicin, the major constituent of peppers. Journal of Experimental & Clinical Cancer Research. Springer Science and Business Media LLC; 2016; 35 10.1186/s13046-016-0417-9
• Dietary flavonoid intake and weight maintenance: three prospective cohorts of 124 086 US men and women followed for up to 24 years Cite
  Bertoia ML, Rimm EB, Mukamal KJ, Hu FB, Willett WC, Cassidy A. Dietary flavonoid intake and weight maintenance: three prospective cohorts of 124 086 US men and women followed for up to 24 years. BMJ. BMJ; 2016;:i17 10.1136/bmj.i17
• An exploration of the estrogen receptor transcription activity of capsaicin analogues via an integrated approach based on in silico prediction and in vitro assays Cite
  Li J, Ma D, Lin Y, Fu J, Zhang A. An exploration of the estrogen receptor transcription activity of capsaicin analogues via an integrated approach based on in silico prediction and in vitro assays. Toxicology Letters. Elsevier BV; 2014; 227:179-188 10.1016/j.toxlet.2014.04.007
• Melatonin content of pepper and tomato fruits: Effects of cultivar and solar radiation Cite
  Riga P, Medina S, García-Flores LA, Gil-Izquierdo Á. Melatonin content of pepper and tomato fruits: Effects of cultivar and solar radiation. Food Chemistry. Elsevier BV; 2014; 156:347-352 10.1016/j.foodchem.2014.01.117
• Pepper Seed Extract Suppresses Invasion and Migration of Human Breast Cancer Cells Cite
  Kim H, Kim M, Kim S, Kim YK. Pepper Seed Extract Suppresses Invasion and Migration of Human Breast Cancer Cells. Nutrition and Cancer. Informa UK Limited; 2013; 66:159-165 10.1080/01635581.2014.853814
• Capsaicin-Mediated tNOX (ENOX2) Up-regulation Enhances Cell Proliferation and Migration in Vitro and in Vivo Cite
  Liu N, Hsieh P, Hsieh M, Zeng Z, Cheng H, Liao J, et al. Capsaicin-Mediated tNOX (ENOX2) Up-regulation Enhances Cell Proliferation and Migration in Vitro and in Vivo. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:2758-2765 10.1021/jf204869w
• Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study Cite
  Masala G, Assedi M, Bendinelli B, Ermini I, Sieri S, Grioni S, et al. Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 132:1127-1136 10.1007/s10549-011-1939-7
• Luteolin induces apoptotic cell death through AIF nuclear translocation mediated by activation of ERK and p38 in human breast cancer cell lines Cite
  Kim MJ, Woo JS, Kwon CH, Kim JH, Kim YK, Kim KH. Luteolin induces apoptotic cell death through AIF nuclear translocation mediated by activation of ERK and p38 in human breast cancer cell lines. Cell Biology International. Wiley; 2012; 36:339-344 10.1042/cbi20110394
• Tumor Cell Growth Inhibition Is Correlated With Levels of Capsaicin Present in Hot Peppers Cite
  Dou D, Ahmad A, Yang H, Sarkar F. Tumor Cell Growth Inhibition Is Correlated With Levels of Capsaicin Present in Hot Peppers. Nutrition and Cancer. Informa UK Limited; 2011; 63:272-281 10.1080/01635581.2011.523497
• Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway Cite
  Thoennissen NH, O'Kelly J, Lu D, Iwanski GB, La DT, Abbassi S, et al. Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway. Oncogene. Springer Science and Business Media LLC; 2009; 29:285-296 10.1038/onc.2009.335
• Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through caspase-independent pathway Cite
  Chen . Capsaicin-induced apoptosis in human breast cancer MCF-7 cells through caspase-independent pathway. Oncology Reports. Spandidos Publications; 2009; 10.3892/or_00000269
• Comparisons of food intake between breast cancer patients and controls in Korean women Cite
  Kim E, Hong Y, Jeon H, Sung M, Sung C. Comparisons of food intake between breast cancer patients and controls in Korean women. Nutrition Research and Practice. The Korean Nutrition Society and The Korean Society of Community Nutrition; 2007; 1:237 10.4162/nrp.2007.1.3.237
• Antioxidant and Antiproliferative Activities of Common Vegetables Cite
  Chu Y, Sun J, Wu X, Liu RH. Antioxidant and Antiproliferative Activities of Common Vegetables. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2002; 50:6910-6916 10.1021/jf020665f