Tag: estradiol
Estradiol (E2): The most important estrogen. Estradiol influences the development and maintenance of feminine characteristics by binding to estrogen receptors. Also known as 17β-estradiol. Testosterone can be converted to estradiol through aromatase activity.
News
- 02/04/17
- Fisetin inhibits formation of a cancer-causing compound from estrogen
- 06/08/14
- Cooking meat produces carcinogen with estrogenic effects
- 09/29/13
- Women with lower estrogen levels have higher HRT-related BC risk
- 09/19/12
- Prenatal estrogen or high fat diet exposure increases BC risk in pups
- 07/19/12
- Aromatase inhibitors are less effective in women with high BMI
- 05/22/12
- Losing weight through diet and exercise can improve hormonal profile
- 08/16/11
- Pomegranate fruit may help prevent estrogen sensitive breast cancer
- 06/18/11
- Bisphenol A promotes mammary cancer in mice
- 04/03/11
- Soy protein may heighten risk of BC by influencing cell signaling
- 10/02/10
- Soy protein isolate may increase PR expression & tumor aggressiveness
- 07/16/10
- Quercetin supplementation may promote breast cancer
- 05/14/10
- Blueberries and black raspberries prevent mammary tumors in rats
Studies
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Obesity-Related Inflammation Reduces Treatment Sensitivity and Promotes Aggressiveness in Luminal Breast Cancer Modulating Oxidative Stress and Mitochondria
Cite
Morla-Barcelo PM, Melguizo-Salom L, Roca P, Nadal-Serrano M, Sastre-Serra J, Torrens-Mas M. Obesity-Related Inflammation Reduces Treatment Sensitivity and Promotes Aggressiveness in Luminal Breast Cancer Modulating Oxidative Stress and Mitochondria. Biomedicines. MDPI AG; 2024; 12:2813 10.3390/biomedicines12122813
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Estrogens and breast cancer
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Kim J, Munster P. Estrogens and breast cancer. Annals of Oncology. Elsevier BV; 2024; 10.1016/j.annonc.2024.10.824
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Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth
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Artham S, Juras PK, Goyal A, Chakraborty P, Byemerwa J, Liu S, et al. Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth. Science Advances. American Association for the Advancement of Science (AAAS); 2024; 10 10.1126/sciadv.adp2442
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Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer
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Javed SR, Skolariki A, Zameer MZ, Lord SR. Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2024; 10.1038/s41416-024-02833-1
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Circulating Estrogen Metabolites and Risk of Breast Cancer among Postmenopausal Women in the Nurses’ Health Study
Cite
Brantley KD, Ziegler RG, Craft NE, Hankinson SE, Eliassen AH. Circulating Estrogen Metabolites and Risk of Breast Cancer among Postmenopausal Women in the Nurses’ Health Study. Cancer Epidemiology, Biomarkers & Prevention. American Association for Cancer Research (AACR); 2024; 10.1158/1055-9965.epi-24-0577
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Non-genetic factors and breast cancer: an umbrella review of meta-analyses
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Yiallourou A, Pantavou K, Markozannes G, Pilavas A, Georgiou A, Hadjikou A, et al. Non-genetic factors and breast cancer: an umbrella review of meta-analyses. BMC Cancer. Springer Science and Business Media LLC; 2024; 24 10.1186/s12885-024-12641-8
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Disentangling the relationships of body mass index and circulating sex hormone concentrations in mammographic density using Mendelian randomization
Cite
Haas CB, Chen H, Harrison T, Fan S, Gago-Dominguez M, Castelao JE, et al. Disentangling the relationships of body mass index and circulating sex hormone concentrations in mammographic density using Mendelian randomization. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2024; 206:295-305 10.1007/s10549-024-07306-w
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Estrogen and alcohol use in women: a targeted literature review
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Handy AB, Greenfield SF, Payne LA. Estrogen and alcohol use in women: a targeted literature review. Archives of Women's Mental Health. Springer Science and Business Media LLC; 2024; 10.1007/s00737-024-01483-9
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Impact of estrogen metabolites on MCF-7 breast cancer cells: Insights from metabolomics study
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Ji J, Gao X, Ye Y, Yadikar N, Xu S, Sun J, et al. Impact of estrogen metabolites on MCF-7 breast cancer cells: Insights from metabolomics study. Food Bioscience. Elsevier BV; 2024; 60:104462 10.1016/j.fbio.2024.104462
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268MO Safety of vaginal estrogen therapy after early-stage breast cancer: A nationwide population-based target trial emulation
Cite
Dumas E, Hamy-Petit A, Gougis P, Laas E, El Ferjaoui S, Jochum F, et al. 268MO Safety of vaginal estrogen therapy after early-stage breast cancer: A nationwide population-based target trial emulation. ESMO Open. Elsevier BV; 2024; 9:103327 10.1016/j.esmoop.2024.103327
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Exploring the Impact of 3,3’-Diindolylmethane on the Urinary Estrogen Profile of Premenopausal Women
Cite
Newman M, Smeaton J. Exploring the Impact of 3,3’-Diindolylmethane on the Urinary Estrogen Profile of Premenopausal Women. Research Square Platform LLC; 2024; 10.21203/rs.3.rs-3944853/v1
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17β-Estradiol promotes metastasis in triple-negative breast cancer through the Calpain/YAP/β-catenin signaling axis
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Niu X, Wang J, Liu J, Yu Q, Ci M. 17β-Estradiol promotes metastasis in triple-negative breast cancer through the Calpain/YAP/β-catenin signaling axis. PLOS ONE. Public Library of Science (PLoS); 2024; 19:e0298184 10.1371/journal.pone.0298184
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Daily supplement of sesame oil prevents postmenopausal osteoporosis via maintaining serum estrogen and aromatase levels in rats
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Hsu C, Ko P, Kwan T, Liu M, Jou I, Lin C, et al. Daily supplement of sesame oil prevents postmenopausal osteoporosis via maintaining serum estrogen and aromatase levels in rats. Scientific Reports. Springer Science and Business Media LLC; 2024; 14 10.1038/s41598-023-50453-1
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Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial
Cite
Cuzick J, Chu K, Keevil B, Brentnall AR, Howell A, Zdenkowski N, et al. Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial. The Lancet Oncology. Elsevier BV; 2023; 10.1016/s1470-2045(23)00578-8
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Prospective Exploratory Study of the Effects of Postoperative Endocrine Medication on the Endometrium in Breast Cancer Patients
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He Y, Li Y, Geng Y, Liu A, Gao F, Ji C, et al. Prospective Exploratory Study of the Effects of Postoperative Endocrine Medication on the Endometrium in Breast Cancer Patients. International Journal of General Medicine. Informa UK Limited; 2023; Volume 16:3677-3687 10.2147/ijgm.s417965
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Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization
Cite
Tin ST, Smith-Byrne K, Ferrari P, Rinaldi S, McCullough ML, Teras LR, et al. Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3249588/v1
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Estrogens and endocrine-disrupting chemicals differentially impact the bioenergetic fluxes of mammary epithelial cells in two- and three-dimensional models
Cite
Lacouture A, Breton Y, Weidmann C, Goulet S, Germain L, Pelletier M, et al. Estrogens and endocrine-disrupting chemicals differentially impact the bioenergetic fluxes of mammary epithelial cells in two- and three-dimensional models. Environment International. Elsevier BV; 2023;:108132 10.1016/j.envint.2023.108132
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Measurable Serum Estradiol and Estrone in Women 36-56 Years During Adjuvant Treatment With Aromatase Inhibitors for a Hormone Receptor-Positive Breast Cancer. Case Studies and Cross-sectional Study Using an Ultra-sensitive LC-MS/MS-Method.
Cite
Van Houdt M, Han S, Pauwels S, Billen J, Neven P. Measurable Serum Estradiol and Estrone in Women 36-56 Years During Adjuvant Treatment With Aromatase Inhibitors for a Hormone Receptor-Positive Breast Cancer. Case Studies and Cross-sectional Study Using an Ultra-sensitive LC-MS/MS-Method.. Clinical Breast Cancer. Elsevier BV; 2023; 23:84-90 10.1016/j.clbc.2022.09.007
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The Role of Cow’s Milk Consumption in Breast Cancer Initiation and Progression
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Melnik BC, John SM, Carrera-Bastos P, Cordain L, Leitzmann C, Weiskirchen R, et al. The Role of Cow’s Milk Consumption in Breast Cancer Initiation and Progression. Current Nutrition Reports. Springer Science and Business Media LLC; 2023; 10.1007/s13668-023-00457-0
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Vaginal Estrogen Therapy for the Genitourinary Symptoms of Menopause: Caution or Reassurance?
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Cathcart-Rake EJ, Ruddy KJ. Vaginal Estrogen Therapy for the Genitourinary Symptoms of Menopause: Caution or Reassurance?. JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2022; 10.1093/jnci/djac113
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Aspirin versus placebo on estrogen levels in postmenopausal women: a double-blind randomized controlled clinical trial
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Oghazian MB, Shirzad N, Ahadi M, Eivazi Adli S, Mollazadeh S, Radfar M. Aspirin versus placebo on estrogen levels in postmenopausal women: a double-blind randomized controlled clinical trial. BMC Pharmacology and Toxicology. Springer Science and Business Media LLC; 2022; 23 10.1186/s40360-022-00571-9
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Estrogenic activity and risk of invasive breast cancer among postmenopausal women in the Nurses' Health Study
Cite
Holder EX, Houghton SC, Sanchez SS, Eliassen AH, Qian J, Bertone-Johnson ER, et al. Estrogenic activity and risk of invasive breast cancer among postmenopausal women in the Nurses' Health Study. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2022;:cebp.1157.2021 10.1158/1055-9965.epi-21-1157
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Natural and Synthetic Estrogens in Chronic Inflammation and Breast Cancer
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Maharjan CK, Mo J, Wang L, Kim M, Wang S, Borcherding N, et al. Natural and Synthetic Estrogens in Chronic Inflammation and Breast Cancer. Cancers. MDPI AG; 2021; 14:206 10.3390/cancers14010206
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Low concentrations of 17β‐estradiol exacerbate tamoxifen resistance in breast cancer treatment through membrane estrogen receptor‐mediated signaling pathways
Cite
Xu Z, Zhao D, Zheng X, Huang B, Pan X, Xia X. Low concentrations of 17β‐estradiol exacerbate tamoxifen resistance in breast cancer treatment through membrane estrogen receptor‐mediated signaling pathways. Environmental Toxicology. Wiley; 2021; 10.1002/tox.23417
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Regulation of estradiol synthesis by aromatase interacting partner (AIPB)
Cite
Bose HS, Whittal RM, Lanier CE, Marshall B, Rajapaksha M, Wheeler BW, et al. Regulation of estradiol synthesis by aromatase interacting partner (AIPB). Molecular and Cellular Biology. American Society for Microbiology; 2021; 10.1128/mcb.00357-21
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Endogenous estrogens—breast cancer and chemoprevention
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Starek-Świechowicz B, Budziszewska B, Starek A. Endogenous estrogens—breast cancer and chemoprevention. Pharmacological Reports. Springer Science and Business Media LLC; 2021; 10.1007/s43440-021-00317-0
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Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors
Cite
Cardona B, Rudel RA. Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors. Environmental Health Perspectives. Environmental Health Perspectives; 2021; 129:077003 10.1289/ehp8608
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High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer
Cite
Traphagen NA, Hosford SR, Jiang A, Marotti JD, Brauer BL, Demidenko E, et al. High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer. Oncogene. Springer Science and Business Media LLC; 2021; 10.1038/s41388-021-01782-w
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Effects of Hormone Therapy on survival, cancer, cardiovascular and dementia risks in 1.5 million women over age 65: a retrospective observational study
Cite
Baik S, McDonald C. Effects of Hormone Therapy on survival, cancer, cardiovascular and dementia risks in 1.5 million women over age 65: a retrospective observational study. Authorea, Inc.; 2021; 10.22541/au.161873076.60547427/v1
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Endogenous hormones and risk of invasive breast cancer in pre- and post-menopausal women: findings from the UK Biobank
Cite
Tin Tin S, Reeves GK, Key TJ. Endogenous hormones and risk of invasive breast cancer in pre- and post-menopausal women: findings from the UK Biobank. British Journal of Cancer. Springer Science and Business Media LLC; 2021; 10.1038/s41416-021-01392-z
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Monitoring serum estradiol levels in breast cancer patients during extended adjuvant letrozole treatment after five years of tamoxifen: a prospective trial
Cite
Faltinová M, Vehmanen L, Lyytinen H, Haanpää M, Hämäläinen E, Tiitinen A, et al. Monitoring serum estradiol levels in breast cancer patients during extended adjuvant letrozole treatment after five years of tamoxifen: a prospective trial. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-021-06168-w
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Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity
Cite
Xu S, Sun J, Zhang Y, Ji J, Sun X. Opposite estrogen effects of estrone and 2-hydroxyestrone on MCF-7 sensitivity to the cytotoxic action of cell growth, oxidative stress and inflammation activity. Ecotoxicology and Environmental Safety. Elsevier BV; 2021; 209:111754 10.1016/j.ecoenv.2020.111754
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Separate and simultaneous binding of tamoxifen and estradiol to human serum albumin: Spectroscopic and molecular modeling investigations
Cite
Moradi N, Ashrafi-Kooshk MR, Chamani J, Shackebaei D, Norouzi F. Separate and simultaneous binding of tamoxifen and estradiol to human serum albumin: Spectroscopic and molecular modeling investigations. Journal of Molecular Liquids. Elsevier BV; 2018; 249:1083-1096 10.1016/j.molliq.2017.11.056
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Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways
Cite
Sun S, Wu J, Lv H, Zhang H, Zhang J, Limbu SM, et al. Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways. Journal of Hazardous Materials. Elsevier BV; 2020; 394:122537 10.1016/j.jhazmat.2020.122537
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Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol
Cite
Palliyaguru DL, Yang L, Chartoumpekis DV, Wendell SG, Fazzari M, Skoko JJ, et al. Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol. Nutrients. MDPI AG; 2020; 12:2282 10.3390/nu12082282
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Associations between Dietary Fiber, the Fecal Microbiota and Estrogen Metabolism in Postmenopausal Women with Breast Cancer
Cite
Zengul AG, Demark-Wahnefried W, Barnes S, Morrow CD, Bertrand B, Berryhill TF, et al. Associations between Dietary Fiber, the Fecal Microbiota and Estrogen Metabolism in Postmenopausal Women with Breast Cancer. Nutrition and Cancer. Informa UK Limited; 2020;:1-10 10.1080/01635581.2020.1784444
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Association between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study
Cite
Elliott MJ, Ennis M, Pritchard KI, Townsley C, Warr D, Elser C, et al. Association between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study. npj Breast Cancer. Springer Science and Business Media LLC; 2020; 6 10.1038/s41523-020-0166-y
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3,3-Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. A prospective clinical trial
Cite
Yerushalmi R, Bargil S, Ber Y, Ozlavo R, Sivan T, Rapson Y, et al. 3,3-Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. A prospective clinical trial. Carcinogenesis. Oxford University Press (OUP); 2020; 41:1395-1401 10.1093/carcin/bgaa050
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The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
Cite
Qureshi R, Picon-Ruiz M, Aurrekoetxea-Rodriguez I, Nunes de Paiva V, D’Amico M, Yoon H, et al. The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development. Cell Metabolism. Elsevier BV; 2020; 31:1154-1172.e9 10.1016/j.cmet.2020.05.008
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Effect of Physical Training on the Levels of Sex Hormones and the Expression of Their Receptors in Rats With Induced Mammary Cancer in Secondary Prevention Model – Preliminary Study
Cite
SIEWIERSKA K, MALICKA I, KOBIERZYCKI C, GRZEGRZOLKA J, PIOTROWSKA A, PASLAWSKA U, et al. Effect of Physical Training on the Levels of Sex Hormones and the Expression of Their Receptors in Rats With Induced Mammary Cancer in Secondary Prevention Model – Preliminary Study. In Vivo. Anticancer Research USA Inc.; 2020; 34:495-501 10.21873/invivo.11800
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The Microbiome–Estrogen Connection and Breast Cancer Risk
Cite
Parida S, Sharma D. The Microbiome–Estrogen Connection and Breast Cancer Risk. Cells. MDPI AG; 2019; 8:1642 10.3390/cells8121642
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Impact of perinatal bisphenol A and 17β estradiol exposure: Comparing hormone receptor response
Cite
Leonel ECR, Campos SGP, Guerra LHA, Bedolo CM, Vilamaior PSL, Calmon MF, et al. Impact of perinatal bisphenol A and 17β estradiol exposure: Comparing hormone receptor response. Ecotoxicology and Environmental Safety. Elsevier BV; 2020; 188:109918 10.1016/j.ecoenv.2019.109918
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17β-estradiol at low concentrations attenuates the efficacy of tamoxifen in breast cancer therapy
Cite
Xu Z, Zheng X, Xia X, Wang X, Luo N, Huang B, et al. 17β-estradiol at low concentrations attenuates the efficacy of tamoxifen in breast cancer therapy. Environmental Pollution. Elsevier BV; 2019; 255:113228 10.1016/j.envpol.2019.113228
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MON-034 Novel Estrogen Activity and Gene Regulation Induced by Personal Care Products in Breast Cancer Cells
Cite
Crease K, Williams C, ma P, Skripnikova E, Wiese T. MON-034 Novel Estrogen Activity and Gene Regulation Induced by Personal Care Products in Breast Cancer Cells. Journal of the Endocrine Society. The Endocrine Society; 2019; 3 10.1210/js.2019-mon-034
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Green Tea Catechin Extract Supplementation Does Not Influence Circulating Sex Hormones and Insulin-Like Growth Factor Axis Proteins in a Randomized Controlled Trial of Postmenopausal Women at High Risk of Breast Cancer
Cite
Samavat H, Wu AH, Ursin G, Torkelson CJ, Wang R, Yu MC, et al. Green Tea Catechin Extract Supplementation Does Not Influence Circulating Sex Hormones and Insulin-Like Growth Factor Axis Proteins in a Randomized Controlled Trial of Postmenopausal Women at High Risk of Breast Cancer. The Journal of Nutrition. Oxford University Press (OUP); 2019; 149:619-627 10.1093/jn/nxy316
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Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases
Cite
Contreras-Zárate MJ, Day NL, Ormond DR, Borges VF, Tobet S, Gril B, et al. Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases. Oncogene. Springer Science and Business Media LLC; 2019; 38:4685-4699 10.1038/s41388-019-0756-z
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Urinary excretion of sex steroid hormone metabolites after consumption of cow milk: a randomized crossover intervention trial
Cite
Michels KB, Binder N, Courant F, Franke AA, Osterhues A. Urinary excretion of sex steroid hormone metabolites after consumption of cow milk: a randomized crossover intervention trial. The American Journal of Clinical Nutrition. Oxford University Press (OUP); 2019; 109:402-410 10.1093/ajcn/nqy279
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The association of urinary estrogen levels with urinary isoflavone levels: Difference between premenopausal women and postmenopausal women
Cite
Yasui T, Ideno Y, Onizuka Y, Nakajima-Shimada J, Lee J, Shinozaki H, et al. The association of urinary estrogen levels with urinary isoflavone levels: Difference between premenopausal women and postmenopausal women. Maturitas. Elsevier BV; 2019; 121:41-47 10.1016/j.maturitas.2018.12.010
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Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach
Cite
Pollack AZ, Mumford SL, Krall JR, Carmichael AE, Sjaarda LA, Perkins NJ, et al. Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach. Environment International. Elsevier BV; 2018; 120:137-144 10.1016/j.envint.2018.07.028
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Estrogen matters in metastasis
Cite
Nair S, Sachdeva G. Estrogen matters in metastasis. Steroids. Elsevier BV; 2018; 138:108-116 10.1016/j.steroids.2018.07.006
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Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation
Cite
Poschner S, Maier-Salamon A, Zehl M, Wackerlig J, Dobusch D, Meshcheryakova A, et al. Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation. Frontiers in Pharmacology. Frontiers Media SA; 2018; 9 10.3389/fphar.2018.00742
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Different menopausal hormone regimens and risk of breast cancer
Cite
Brusselaers N, Tamimi R, Konings P, Rosner B, Adami H, Lagergren J. Different menopausal hormone regimens and risk of breast cancer. Annals of Oncology. Elsevier BV; 2018; 29:1771-1776 10.1093/annonc/mdy212
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Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression
Cite
Yuan S, Huang C, Ji X, Ma M, Rao K, Wang Z. Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression. Ecotoxicology and Environmental Safety. Elsevier BV; 2018; 160:1-9 10.1016/j.ecoenv.2018.05.025
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Effect of 17β-estradiol on estrogen receptor negative breast cancer cells in an osteolytic mouse model
Cite
Cohen DJ, Patel V, Verma A, Boyan BD, Schwartz Z. Effect of 17β-estradiol on estrogen receptor negative breast cancer cells in an osteolytic mouse model. Steroids. Elsevier BV; 2019; 142:28-33 10.1016/j.steroids.2017.10.010
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Estradiol impairs the antiproliferative and proapoptotic effect of Zoledronic acid in hormone sensitive breast cancer cells in vitro
Cite
Gschwantler-Kaulich D, Weingartshofer S, Grunt TW, Mairhofer M, Tan Y, Gamper J, et al. Estradiol impairs the antiproliferative and proapoptotic effect of Zoledronic acid in hormone sensitive breast cancer cells in vitro. PLOS ONE. Public Library of Science (PLoS); 2017; 12:e0185566 10.1371/journal.pone.0185566
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Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer
Cite
Melisko ME, Goldman ME, Hwang J, De Luca A, Fang S, Esserman LJ, et al. Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer. JAMA Oncology. American Medical Association (AMA); 2017; 3:313 10.1001/jamaoncol.2016.3904
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A hydroxylated flavonol, fisetin inhibits the formation of a carcinogenic estrogen metabolite
Cite
Meng X, Sun H, Yang L, Yin R, Qi L. A hydroxylated flavonol, fisetin inhibits the formation of a carcinogenic estrogen metabolite. Steroids. Elsevier BV; 2017; 119:53-56 10.1016/j.steroids.2017.01.002
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Associations of obesity and physical activity with serum and intratumoral sex steroid hormone levels among postmenopausal women with breast cancer: analysis of paired serum and tumor tissue samples
Cite
Kakugawa Y, Tada H, Kawai M, Suzuki T, Nishino Y, Kanemura S, et al. Associations of obesity and physical activity with serum and intratumoral sex steroid hormone levels among postmenopausal women with breast cancer: analysis of paired serum and tumor tissue samples. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 162:115-125 10.1007/s10549-016-4094-3
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Impact of low concentrations of phthalates on the effects of 17β-estradiol in MCF-7 breast cancer cells
Cite
Chen F, Chien M, Chern IY. Impact of low concentrations of phthalates on the effects of 17β-estradiol in MCF-7 breast cancer cells. Taiwanese Journal of Obstetrics and Gynecology. Elsevier BV; 2016; 55:826-834 10.1016/j.tjog.2015.11.003
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Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model
Cite
Hilakivi-Clarke L, Wärri A, Bouker KB, Zhang X, Cook KL, Jin L, et al. Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. Journal of the National Cancer Institute. Oxford University Press (OUP); 2016; 109:djw188 10.1093/jnci/djw188
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Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes
Cite
Rondón-Lagos M, Rangel N, Di Cantogno LV, Annaratone L, Castellano I, Russo R, et al. Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes. Endocrine-Related Cancer. Bioscientifica; 2016; 23:635-650 10.1530/erc-16-0078
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Endogenous Estrogens, Estrogen Metabolites, and Breast Cancer Risk in Postmenopausal Chinese Women
Cite
Moore SC, Matthews CE, Ou Shu X, Yu K, Gail MH, Xu X, et al. Endogenous Estrogens, Estrogen Metabolites, and Breast Cancer Risk in Postmenopausal Chinese Women. Journal of the National Cancer Institute. Oxford University Press (OUP); 2016; 108:djw103 10.1093/jnci/djw103
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Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo
Cite
Deb P, Bhan A, Hussain I, Ansari KI, Bobzean SA, Pandita TK, et al. Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. Gene. Elsevier BV; 2016; 590:234-243 10.1016/j.gene.2016.05.009
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Soy isoflavone exposure through all life stages accelerates 17β-estradiol-induced mammary tumor onset and growth, yet reduces tumor burden, in ACI rats
Cite
Möller FJ, Pemp D, Soukup ST, Wende K, Zhang X, Zierau O, et al. Soy isoflavone exposure through all life stages accelerates 17β-estradiol-induced mammary tumor onset and growth, yet reduces tumor burden, in ACI rats. Archives of Toxicology. Springer Science and Business Media LLC; 2016; 90:1907-1916 10.1007/s00204-016-1674-2
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Associations of sex steroid hormones with mortality in women with breast cancer
Cite
Duggan C, Stanczyk F, Campbell K, Neuhouser ML, Baumgartner RN, Baumgartner KB, et al. Associations of sex steroid hormones with mortality in women with breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 155:559-567 10.1007/s10549-016-3704-4
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Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor–Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy
Cite
Bellet M, Gray KP, Francis PA, Láng I, Ciruelos E, Lluch A, et al. Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor–Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2016; 34:1584-1593 10.1200/jco.2015.61.2259
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Alcohol Consumption and Urinary Estrogens and Estrogen Metabolites in Premenopausal Women
Cite
Hartman TJ, Sisti JS, Hankinson SE, Xu X, Eliassen AH, Ziegler R. Alcohol Consumption and Urinary Estrogens and Estrogen Metabolites in Premenopausal Women. Hormones and Cancer. Springer Science and Business Media LLC; 2016; 7:65-74 10.1007/s12672-015-0249-7
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A phase II trial of low-dose estradiol in postmenopausal women with advanced breast cancer and acquired resistance to aromatase inhibition
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Dietary Fat and Fiber Intakes Are Not Associated with Patterns of Urinary Estrogen Metabolites in Premenopausal Women
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Prediagnostic Sex Steroid Hormones in Relation to Male Breast Cancer Risk
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Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer
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Hormone Use in Food Animal Production: Assessing Potential Dietary Exposures and Breast Cancer Risk
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Breast Cancer Cell Apoptosis with Phytoestrogens Is Dependent on an Estrogen-Deprived State
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Associations between cadmium exposure and circulating levels of sex hormones in postmenopausal women
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Chemopreventive and Therapeutic Activity of Dietary Blueberry against Estrogen-Mediated Breast Cancer
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Estradiol increases ER-negative breast cancer metastasis in an experimental model
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The effect of low doses of zearalenone and its metabolites on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
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Sex Hormone Levels and Risk of Breast Cancer With Estrogen Plus Progestin
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Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells
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Plasma enterolactone and breast cancer risk in the Nurses’ Health Study II
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Changes in Estradiol and Testosterone Levels in Postmenopausal Women After Changes in Body Mass Index
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Energy-containing beverages: reproductive hormones and ovarian function in the BioCycle Study
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Favorable Changes in Serum Estrogens and Other Biologic Factors After Weight Loss in Breast Cancer Survivors Who are Overweight or Obese
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N-3 Poly-Unsaturated Fatty Acids Shift Estrogen Signaling to Inhibit Human Breast Cancer Cell Growth
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Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up
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Acute genistein treatment mimics the effects of estradiol by enhancing place learning and impairing response learning in young adult female rats
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Suppression of Plasma Estrogen Levels by Letrozole and Anastrozole Is Related to Body Mass Index in Patients With Breast Cancer
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Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial
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Estrone and Estrone Sulfate Concentrations in Milk and Milk Fractions
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Quantifying Mediating Effects of Endogenous Estrogen and Insulin in the Relation between Obesity, Alcohol Consumption, and Breast Cancer
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Comparison of estrone and 17β-estradiol levels in commercial goat and cow milk
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Exposure to Ionizing Radiation Causes Long-Term Increase in Serum Estradiol and Activation of PI3K-Akt Signaling Pathway in Mouse Mammary Gland
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Suman S, Johnson MD, Fornace AJ, Datta K. Exposure to Ionizing Radiation Causes Long-Term Increase in Serum Estradiol and Activation of PI3K-Akt Signaling Pathway in Mouse Mammary Gland. International Journal of Radiation Oncology*Biology*Physics. Elsevier BV; 2012; 84:500-507 10.1016/j.ijrobp.2011.12.033
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The estrogenic potential of salicylate esters and their possible risks in foods and cosmetics
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Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway
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Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women
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Effects of multiple daily genistein treatments on delayed alternation and a differential reinforcement of low rates of responding task in middle-aged rats
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Red Versus White Wine as a Nutritional Aromatase Inhibitor in Premenopausal Women: A Pilot Study
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Serum leptin level and waist-to-hip ratio (WHR) predict the overall survival of metastatic breast cancer (MBC) patients treated with aromatase inhibitors (AIs)
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Proliferative effect of whey from cows' milk obtained at two different stages of pregnancy measured in MCF-7 cells
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Alcohol Exposure In Utero Leads to Enhanced Prepubertal Mammary Development and Alterations in Mammary IGF and Estradiol Systems
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Pomegranate extract demonstrate a selective estrogen receptor modulator profile in human tumor cell lines and in vivo models of estrogen deprivation
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Sreeja S, Santhosh Kumar TR, Lakshmi BS, Sreeja S. Pomegranate extract demonstrate a selective estrogen receptor modulator profile in human tumor cell lines and in vivo models of estrogen deprivation. The Journal of Nutritional Biochemistry. Elsevier BV; 2012; 23:725-732 10.1016/j.jnutbio.2011.03.015
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An analysis of vitamin D (Vit D) and serum estrogens in postmenopausal (PM) breast cancer (BC) patients receiving aromatase inhibitors (AIs).
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A dose-finding clinical trial of mushroom powder in postmenopausal breast cancer survivors for secondary breast cancer prevention.
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Bisphenol A Increases Mammary Cancer Risk in Two Distinct Mouse Models of Breast Cancer
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Effects of Tomato- and Soy-Rich Diets on the IGF-I Hormonal Network: A Crossover Study of Postmenopausal Women at High Risk for Breast Cancer
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Effects of Non-Digestible Carbohydrates on the Growth of Estrogen-Dependent Human Breast Cancer (MCF-7) Tumors Implanted in Ovariectomized Athymic Mice
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Enhanced Mammary Progesterone Receptor-A Isoform Activity in the Promotion of Mammary Tumor Progression by Dietary Soy in Rats
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Dietary quercetin exacerbates the development of estrogen-induced breast tumors in female ACI rats
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Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth
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Casa AJ, Potter AS, Malik S, Lazard Z, Kuiatse I, Kim H, et al. Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2011; 132:61-73 10.1007/s10549-011-1540-0
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Does dietary estrogen intake from meat relate to the incidence of hormone-dependent cancers?
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Effect of successful weight loss program on biomarkers for breast cancer in postmenopausal high-risk women.
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Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats
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Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC)
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Abstract 1887: Distinct molecular targets of blueberry and black raspberry in breast cancer prevention
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Relationship Between Plasma Estradiol Levels and Estrogen-Responsive Gene Expression in Estrogen Receptor–Positive Breast Cancer in Postmenopausal Women
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Analgesic Use and Sex Steroid Hormone Concentrations in Postmenopausal Women
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Menopausal hormone therapy and breast cancer risk: Impact of different treatments. The European Prospective Investigation into Cancer and Nutrition
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Physical Activity and Postmenopausal Breast Cancer: Proposed Biologic Mechanisms and Areas for Future Research
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Circulating Steroid Hormone Levels and Risk of Breast Cancer for Postmenopausal Women
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Cytotoxic and xenoestrogenic effects via biotransformation of trans-anethole on isolated rat hepatocytes and cultured MCF-7 human breast cancer cells
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Dietary Seaweed Modifies Estrogen and Phytoestrogen Metabolism in Healthy Postmenopausal Women
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Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies
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Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3′-diindolylmethane and its parent compound indole-3-carbinol
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The effects ofAnethum graveolensL. on female reproductive system
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The Effect of the Phytoestrogens Genistein, Daidzein, and Equol on the Growth of Tamoxifen-Resistant T47D/PKCα
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Tonetti DA, Zhang Y, Zhao H, Lim S, Constantinou AI. The Effect of the Phytoestrogens Genistein, Daidzein, and Equol on the Growth of Tamoxifen-Resistant T47D/PKCα. Nutrition and Cancer. Informa UK Limited; 2007; 58:222-229 10.1080/01635580701328545
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Soy processing influences growth of estrogen-dependent breast cancer tumors
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Phytoestrogens and breast cancer: a complex story
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Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha
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Dietary Berries and Ellagic Acid Diminish Estrogen-Mediated Mammary Tumorigenesis ∈ ACI rats
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Effect of medicinal botanicals in breast cancer cell lines with different estrogen receptor expression
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Houghton FD, Elm MS, Eagon PK. Effect of medicinal botanicals in breast cancer cell lines with different estrogen receptor expression. Cancer Res. American Association for Cancer Research; 2005; 65:1360-1360. https://cancerres.aacrjournals.org/content/65/9_Supplement/1360.3.abstract
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Cadmium induces mitogenic signaling in breast cancer cell by an ERα-dependent mechanism
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Evaluation of the Estrogenic Effects of Legume Extracts Containing Phytoestrogens
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Estrogen-like effects of ethanol extracts from several Chinese legumes on MCF-7 cell
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Effects of ethanol extracts from Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) on estrogen and progesterone receptor phenotypes of MCF-7/BOS cells
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Zhao Q, Huang X, Lou Y, Weber N, Proksch P. Effects of ethanol extracts from Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) on estrogen and progesterone receptor phenotypes of MCF-7/BOS cells. Phytotherapy Research. Wiley; 2007; 21:648-652 10.1002/ptr.2135
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The Cooked Meat–Derived Genotoxic Carcinogen 2-Amino-3-Methylimidazo[4,5-b]Pyridine Has Potent Hormone-Like Activity: Mechanistic Support for a Role in Breast Cancer
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Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue
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Wang L, Huang Y, Liu S, Yan P, Lin YC. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC Cancer. Springer Science and Business Media LLC; 2008; 8 10.1186/1471-2407-8-208
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Lycopene and other carotenoids inhibit estrogenic activity of 17β-estradiol and genistein in cancer cells
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Hirsch K, Atzmon A, Danilenko M, Levy J, Sharoni Y. Lycopene and other carotenoids inhibit estrogenic activity of 17β-estradiol and genistein in cancer cells. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2006; 104:221-230 10.1007/s10549-006-9405-7
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Estrogenic Effects of Extracts from Cabbage, Fermented Cabbage, and Acidified Brussels Sprouts on Growth and Gene Expression of Estrogen-Dependent Human Breast Cancer (MCF-7) Cells
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Ju YH, Carlson KE, Sun J, Pathak D, Katzenellenbogen BS, Katzenellenbogen JA, et al. Estrogenic Effects of Extracts from Cabbage, Fermented Cabbage, and Acidified Brussels Sprouts on Growth and Gene Expression of Estrogen-Dependent Human Breast Cancer (MCF-7) Cells. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2000; 48:4628-4634 10.1021/jf000164z
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Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
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Kim ND, Mehta R, Yu W, Neeman I, Livney T, Amichay A, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2002; 71:203-217 10.1023/a:1014405730585
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Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice
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Mori-Okamoto J, Otawara-Hamamoto Y, Yamato H, Yoshimura H. Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice. Journal of Ethnopharmacology. Elsevier BV; 2004; 92:93-101 10.1016/j.jep.2004.02.006
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Naturally Occurring Estrogens in Processed Milk and in Raw Milk (from Gestated Cows)
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Malekinejad H, Scherpenisse P, Bergwerff AA. Naturally Occurring Estrogens in Processed Milk and in Raw Milk (from Gestated Cows). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2006; 54:9785-9791 10.1021/jf061972e
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Milk Inhibits the Regression of 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Ovariectomized Rats
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Qin L, Xu J, Tezuka H, Wang P, Hoshi K. Milk Inhibits the Regression of 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Ovariectomized Rats. Nutrition and Cancer. Informa UK Limited; 2008; 60:505-510 10.1080/01635580801927452
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Dietary Fiber Intake and Endogenous Serum Hormone Levels in Naturally Postmenopausal Mexican American Women: The Multiethnic Cohort Study
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Monroe KR, Murphy SP, Henderson BE, Kolonel LN, Stanczyk FZ, Adlercreutz H, et al. Dietary Fiber Intake and Endogenous Serum Hormone Levels in Naturally Postmenopausal Mexican American Women: The Multiethnic Cohort Study. Nutrition and Cancer. Informa UK Limited; 2007; 58:127-135 10.1080/01635580701327935
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Association between Alcohol Intake and Serum Sex Hormones and Peptides Differs by Tamoxifen Use in Breast Cancer Survivors
Cite
Wayne S, Neuhouser ML, Ulrich CM, Koprowski C, Wiggins C, Baumgartner KB, et al. Association between Alcohol Intake and Serum Sex Hormones and Peptides Differs by Tamoxifen Use in Breast Cancer Survivors. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2008; 17:3224-3232 10.1158/1055-9965.epi-08-0171