Tag: omega6

News

07/11/25

Fast and ultra-processed foods linked to breast cancer risk

03/27/25

How linoleic acid promotes triple negative tumor growth

12/08/20

Linoleic acid furthers angiogenesis of triple negative breast cancer

11/04/18

Omega-3 fats reduce tumor growth and increase survival in mice

05/07/17

Vegetable oil linoleic acid promotes migration & invasion of TN cells

04/16/16

Some factors promoting breast cancer metastasis

06/27/15

High corn oil diet promotes mammary tumor development in animal model

03/08/15

Low omega-3 to omega-6 ratio linked to increased BC risk

03/24/14

Common omega-6 fat promotes metastasis of TN breast cancer cells

11/30/12

Fish fats reduce BC risk whereas some other types of fat increase it

09/12/11

Fish oil reduces breast cancer risk by depleting arachidonic acid

12/08/10

Intermittent calorie restriction plus fish oil help prevent BC

05/19/10

Omega-6 rich corn oil reduces effectiveness of tamoxifen

Foods

• • canola oil
  • corn oil
  • safflower oil
  • soybean oil
  • sunflower oil

Studies

• Linoleic acid induces migration and invasion through TLR4 in breast cancer cells Cite
  Zaragoza KP, Castillo-Sanchez R, Sanchez-Juarez M, Cortes-Reynosa P, Salazar EP. Linoleic acid induces migration and invasion through TLR4 in breast cancer cells. Tissue and Cell. Elsevier BV; 2025; 96:103009 10.1016/j.tice.2025.103009
• Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling Cite
  Koundouros N, Nagiec MJ, Bullen N, Noch EK, Burgos-Barragan G, Li Z, et al. Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling. Science. American Association for the Advancement of Science (AAAS); 2025; 387 10.1126/science.adm9805
• Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: a population-based cohort study in UK Biobank Cite
  Zhang Y, Sun Y, Song S, Khankari NK, Brenna JT, Shen Y, et al. Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: a population-based cohort study in UK Biobank. Cold Spring Harbor Laboratory; 2024; 10.1101/2024.01.21.24301568
• Chemical Compositions and Essential Fatty Acid Analysis of Selected Vegetable Oils and Fats Cite
  Ojha PK, Poudel DK, Rokaya A, Maharjan S, Timsina S, Poudel A, et al. Chemical Compositions and Essential Fatty Acid Analysis of Selected Vegetable Oils and Fats. Compounds. MDPI AG; 2024; 4:37-70 10.3390/compounds4010003
• High linoleic acid levels in red blood cells predict a poor response to neoadjuvant chemotherapy in HER2-positive breast cancer patients Cite
  Valenzuela R, Walbaum B, Farias C, Acevedo F, Vargas C, Bennett JT, et al. High linoleic acid levels in red blood cells predict a poor response to neoadjuvant chemotherapy in HER2-positive breast cancer patients. Nutrition. Elsevier BV; 2024;:112357 10.1016/j.nut.2024.112357
• New Insights into Prospective Health Potential of ω-3 PUFAs Cite
  Lakshimi VI, Kavitha M. New Insights into Prospective Health Potential of ω-3 PUFAs. Current Nutrition Reports. Springer Science and Business Media LLC; 2023; 10.1007/s13668-023-00508-6
• Dietary Omega-6/Omega-3 Polyunsaturated Fatty Acid (PUFA) and Omega-3 Are Associated With General and Abdominal Obesity in Adults: UK National Diet and Nutritional Survey Cite
  Albar SA. Dietary Omega-6/Omega-3 Polyunsaturated Fatty Acid (PUFA) and Omega-3 Are Associated With General and Abdominal Obesity in Adults: UK National Diet and Nutritional Survey. Cureus. Cureus, Inc.; 2022; 10.7759/cureus.30209
• Association of dietary intake of n-3 polyunsaturated fatty acids with breast cancer risk in pre- and postmenopausal Chinese women Cite
  Zhang Z, Ho SC, Liu K, Mo X, Feng X, Li L, et al. Association of dietary intake of n-3 polyunsaturated fatty acids with breast cancer risk in pre- and postmenopausal Chinese women. Menopause. Ovid Technologies (Wolters Kluwer Health); 2022; 29:932-943 10.1097/gme.0000000000001990
• Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators Cite
  Ouldamer L, Jourdan M, Pinault M, Arbion F, Goupille C. Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators. Biomedicines. MDPI AG; 2022; 10:995 10.3390/biomedicines10050995
• Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells Cite
  Biswas P, Datta C, Rathi P, Bhattacharjee A. Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells. Prostaglandins & Other Lipid Mediators. Elsevier BV; 2022;:106637 10.1016/j.prostaglandins.2022.106637
• Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels–A systematic review. Cite
  Mantzioris E, Muhlhausler BS, Villani A. Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels–A systematic review.. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2022; 176:102387 10.1016/j.plefa.2021.102387
• Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids Cite
  Luo H, Chen C, Li X, Zhang X, Su C, Liu Y, et al. Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids. STEM CELLS. Wiley; 2021; 10.1002/stem.3452
• Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy Cite
  Ormiston K, Gaudier-Diaz MM, TinKai T, Fitzgerald J, Cole RM, Andridge R, et al. Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy. Nutritional Neuroscience. Informa UK Limited; 2021;:1-9 10.1080/1028415x.2021.1998296
• Role of Src/FAK in migration and invasion mediated by extracellular vesicles from MDA-MB-231 cells stimulated with linoleic acid Cite
  Ramirez-Ricardo J, Leal-Orta E, Garcia-Hernandez A, Diaz-Aragon R, Cortes-Reynosa P, Thompson-Bonilla R, et al. Role of Src/FAK in migration and invasion mediated by extracellular vesicles from MDA-MB-231 cells stimulated with linoleic acid. Medical Oncology. Springer Science and Business Media LLC; 2021; 38 10.1007/s12032-021-01485-y
• The central role of mitochondria in the relationship between dietary lipids and cancer progression Cite
  Varela-López A, Vera-Ramírez L, Giampieri F, Navarro-Hortal MD, Forbes-Hernández TY, Battino M, et al. The central role of mitochondria in the relationship between dietary lipids and cancer progression. Seminars in Cancer Biology. Elsevier BV; 2021; 10.1016/j.semcancer.2021.01.001
• Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids Cite
  Hillyer LM, Hucik B, Baracuhy EM, Lin Z, Muller WJ, Robinson LE, et al. Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids. Nutrients. MDPI AG; 2020; 12:3901 10.3390/nu12123901
• Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells Cite
  Diaz-Aragon R, Ramirez-Ricardo J, Cortes-Reynosa P, Simoni-Nieves A, Gomez-Quiroz L, Perez Salazar E. Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2019; 457:119-132 10.1007/s11010-019-03517-8
• Altered Levels of Desaturation and ω-6 Fatty Acids in Breast Cancer Patients’ Red Blood Cell Membranes Cite
  Amézaga J, Ugartemendia G, Larraioz A, Bretaña N, Iruretagoyena A, Camba J, et al. Altered Levels of Desaturation and ω-6 Fatty Acids in Breast Cancer Patients’ Red Blood Cell Membranes. Metabolites. MDPI AG; 2020; 10:469 10.3390/metabo10110469
• Effects of diets high in corn oil or in extra virgin olive oil on oxidative stress in an experimental model of breast cancer Cite
  Escrich R, Vela E, Solanas M, Moral R. Effects of diets high in corn oil or in extra virgin olive oil on oxidative stress in an experimental model of breast cancer. Molecular Biology Reports. Springer Science and Business Media LLC; 2020; 47:4923-4932 10.1007/s11033-020-05492-6
• Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population – a Case-Control Study Cite
  DYDJOW-BENDEK D, ZAGOŹDŹON P. Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population – a Case-Control Study. In Vivo. Anticancer Research USA Inc.; 2019; 34:423-431 10.21873/invivo.11791
• A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways Cite
  Escrich R, Costa I, Moreno M, Cubedo M, Vela E, Escrich E, et al. A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways. The Journal of Nutritional Biochemistry. Elsevier BV; 2019; 64:218-227 10.1016/j.jnutbio.2018.11.001
• Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival Cite
  Khadge S, Thiele GM, Sharp JG, McGuire TR, Klassen LW, Black PN, et al. Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival. Clinical & Experimental Metastasis. Springer Science and Business Media LLC; 2018; 35:797-818 10.1007/s10585-018-9941-7
• Biomarker of long-chain n-3 fatty acid intake and breast cancer: Accumulative evidence from an updated meta-analysis of epidemiological studies Cite
  Yang B, Ren XL, Wang ZY, Wang L, Zhao F, Guo XJ, et al. Biomarker of long-chain n-3 fatty acid intake and breast cancer: Accumulative evidence from an updated meta-analysis of epidemiological studies. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2018; 59:3152-3164 10.1080/10408398.2018.1485133
• Linoleic acid induces an increased response to insulin in MDA‐MB‐231 breast cancer cells Cite
  Rodriguez‐Monterrosas C, Diaz‐Aragon R, Cortes‐Reynosa P, Salazar EP. Linoleic acid induces an increased response to insulin in MDA‐MB‐231 breast cancer cells. Journal of Cellular Biochemistry. Wiley; 2018; 119:5413-5425 10.1002/jcb.26694
• Abstract 5374: Polyunsaturated fatty acids (PUFAs) alter the epigenetic landscape in MDA-MB-231 triple negative breast carcinoma (TNBC) Cite
  Chattin AM, O'Brien M, Pardini RS. Abstract 5374: Polyunsaturated fatty acids (PUFAs) alter the epigenetic landscape in MDA-MB-231 triple negative breast carcinoma (TNBC). Molecular and Cellular Biology, Genetics. American Association for Cancer Research; 2017; 10.1158/1538-7445.am2017-5374
• Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice Cite
  Nguyen NM, de Oliveira Andrade F, Jin L, Zhang X, Macon M, Cruz MI, et al. Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice. Breast Cancer Research. Springer Science and Business Media LLC; 2017; 19 10.1186/s13058-017-0866-x
• The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells Cite
  Hejr H, Ghareghani M, Zibara K, Ghafari M, Sadri F, Salehpour Z, et al. The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells. Neuroscience Letters. Elsevier BV; 2017; 651:216-225 10.1016/j.neulet.2017.05.020
• Linoleic acid induces migration and invasion through FFAR4- and PI3K-/Akt-dependent pathway in MDA-MB-231 breast cancer cells Cite
  Serna-Marquez N, Diaz-Aragon R, Reyes-Uribe E, Cortes-Reynosa P, Salazar EP. Linoleic acid induces migration and invasion through FFAR4- and PI3K-/Akt-dependent pathway in MDA-MB-231 breast cancer cells. Medical Oncology. Springer Science and Business Media LLC; 2017; 34 10.1007/s12032-017-0969-3
• Fatty acid intake and erythrocyte fatty acid profile in women with breast, ovarian and cervical cancers Cite
  Bannikoppa P, Dhayanand J, Madhukumar R, Padmanabhan A, Bafna U, Vijayakumar M, et al. Fatty acid intake and erythrocyte fatty acid profile in women with breast, ovarian and cervical cancers. Clinical Nutrition ESPEN. Elsevier BV; 2017; 19:59-63 10.1016/j.clnesp.2017.03.001
• Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland Cite
  Manzanares MÁ, de Miguel C, Ruiz de Villa MC, Santella RM, Escrich E, Solanas M. Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland. The Journal of Nutritional Biochemistry. Elsevier BV; 2017; 43:68-77 10.1016/j.jnutbio.2017.01.016
• Abstract 4536: Polyunsaturated fatty acids alter the epigenetic landscape in triple-negative breast cancer (TNBC) Cite
  Chattin AM, O’Brien M, Pardini RS. Abstract 4536: Polyunsaturated fatty acids alter the epigenetic landscape in triple-negative breast cancer (TNBC). Molecular and Cellular Biology, Genetics. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-4536
• Content of Crude Protein, Fixed Oil and Lecithin in Sudanese Seed Accessions of Fenugreek (Trigonella foenum-graecum L.) Cite
  Bashir NAO, Elhussein SA, Taha AA. Content of Crude Protein, Fixed Oil and Lecithin in Sudanese Seed Accessions of Fenugreek (Trigonella foenum-graecum L.). Pakistan Journal of Nutrition. Science Alert; 2015; 14:907-912 10.3923/pjn.2015.907.912
• Polyunsaturated fatty acid interactions and breast cancer incidence: a population-based case-control study on Long Island, New York Cite
  Khankari NK, Bradshaw PT, Steck SE, He K, Olshan AF, Shen J, et al. Polyunsaturated fatty acid interactions and breast cancer incidence: a population-based case-control study on Long Island, New York. Annals of Epidemiology. Elsevier BV; 2015; 25:929-935 10.1016/j.annepidem.2015.09.003
• Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231 Cite
  Mansara PP, Deshpande RA, Vaidya MM, Kaul-Ghanekar R. Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0136542 10.1371/journal.pone.0136542
• Omega-3 and Omega-6 Fatty Acids in Blood and Breast Tissue of High-Risk Women and Association with Atypical Cytomorphology Cite
  Hidaka BH, Li S, Harvey KE, Carlson SE, Sullivan DK, Kimler BF, et al. Omega-3 and Omega-6 Fatty Acids in Blood and Breast Tissue of High-Risk Women and Association with Atypical Cytomorphology. Cancer Prevention Research. American Association for Cancer Research (AACR); 2015; 8:359-364 10.1158/1940-6207.capr-14-0351
• A high-fat diet rich in corn oil reduces spontaneous locomotor activity and induces insulin resistance in mice Cite
  Wong CK, Botta A, Pither J, Dai C, Gibson WT, Ghosh S. A high-fat diet rich in corn oil reduces spontaneous locomotor activity and induces insulin resistance in mice. The Journal of Nutritional Biochemistry. Elsevier BV; 2015; 26:319-326 10.1016/j.jnutbio.2014.11.004
• A Higher Dietary Ratio of Long-Chain Omega-3 to Total Omega-6 Fatty Acids for Prevention of COX-2-Dependent Adenocarcinomas Cite
  DiNicolantonio JJ, McCarty MF, Chatterjee S, Lavie CJ, O’Keefe JH. A Higher Dietary Ratio of Long-Chain Omega-3 to Total Omega-6 Fatty Acids for Prevention of COX-2-Dependent Adenocarcinomas. Nutrition and Cancer. Informa UK Limited; 2014; 66:1279-1284 10.1080/01635581.2014.956262
• Fatty acid profiles, meat quality, and sensory attributes of organic versus conventional dairy beef steers Cite
  Bjorklund E, Heins B, DiCostanzo A, Chester-Jones H. Fatty acid profiles, meat quality, and sensory attributes of organic versus conventional dairy beef steers. Journal of Dairy Science. American Dairy Science Association; 2014; 97:1828-1834 10.3168/jds.2013-6984
• Impact of grass/forage feeding versus grain finishing on beef nutrients and sensory quality: The U.S. experience Cite
  Van Elswyk ME, McNeill SH. Impact of grass/forage feeding versus grain finishing on beef nutrients and sensory quality: The U.S. experience. Meat Science. Elsevier BV; 2014; 96:535-540 10.1016/j.meatsci.2013.08.010
• Prospective Associations between Plasma Saturated, Monounsaturated and Polyunsaturated Fatty Acids and Overall and Breast Cancer Risk – Modulation by Antioxidants: A Nested Case-Control Study Cite
  Pouchieu C, Chajès V, Laporte F, Kesse-Guyot E, Galan P, Hercberg S, et al. Prospective Associations between Plasma Saturated, Monounsaturated and Polyunsaturated Fatty Acids and Overall and Breast Cancer Risk – Modulation by Antioxidants: A Nested Case-Control Study. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e90442 10.1371/journal.pone.0090442
• Arachidonic acid promotes migration and invasion through a PI3K/Akt-dependent pathway in MDA-MB-231 breast cancer cells Cite
  Villegas-Comonfort S, Castillo-Sanchez R, Serna-Marquez N, Cortes-Reynosa P, Salazar EP. Arachidonic acid promotes migration and invasion through a PI3K/Akt-dependent pathway in MDA-MB-231 breast cancer cells. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2014; 90:169-177 10.1016/j.plefa.2014.01.007
• Relations of omega-3 and omega-6 intake with mammographic breast density Cite
  Diorio C, Dumas I. Relations of omega-3 and omega-6 intake with mammographic breast density. Cancer Causes & Control. Springer Science and Business Media LLC; 2014; 25:339-351 10.1007/s10552-013-0335-5
• Proteomic Changes Induced by Effective Chemopreventive Ratios of n-3:n-6 Fatty Acids and Tamoxifen against MNU-Induced Mammary Cancer in the Rat Cite
  Skibinski CG, Thompson HJ, Das A, Manni A, Bortner JD, Stanley A, et al. Proteomic Changes Induced by Effective Chemopreventive Ratios of n-3:n-6 Fatty Acids and Tamoxifen against MNU-Induced Mammary Cancer in the Rat. Cancer Prevention Research. American Association for Cancer Research (AACR); 2013; 6:979-988 10.1158/1940-6207.capr-13-0152
• Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort Cite
  Olsen KS, Fenton C, Frøyland L, Waaseth M, Paulssen RH, Lund E. Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e67270 10.1371/journal.pone.0067270
• Erythrocyte Omega-6 and Omega-3 Fatty Acids and Mammographic Breast Density Cite
  Hudson AG, Reeves KW, Modugno F, Wilson JW, Evans RW, Vogel VG, et al. Erythrocyte Omega-6 and Omega-3 Fatty Acids and Mammographic Breast Density. Nutrition and Cancer. Informa UK Limited; 2013; 65:410-416 10.1080/01635581.2013.760744
• Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue Cite
  Pender-Cudlip MC, Krag KJ, Martini D, Yu J, Guidi A, Skinner SS, et al. Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue. Cancer Science. Wiley; 2013; 104:760-764 10.1111/cas.12129
• Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells Cite
  Serna-Marquez N, Villegas-Comonfort S, Galindo-Hernandez O, Navarro-Tito N, Millan A, Salazar EP. Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. Cellular Oncology. Springer Science and Business Media LLC; 2012; 36:65-77 10.1007/s13402-012-0114-4
• Dietary Intake of Specific Fatty Acids and Breast Cancer Risk Among Postmenopausal Women in the VITAL Cohort Cite
  Sczaniecka AK, Brasky TM, Lampe JW, Patterson RE, White E. Dietary Intake of Specific Fatty Acids and Breast Cancer Risk Among Postmenopausal Women in the VITAL Cohort. Nutrition and Cancer. Informa UK Limited; 2012; 64:1131-1142 10.1080/01635581.2012.718033
• The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis Cite
  Kang JX, Liu A. The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis. Cancer and Metastasis Reviews. Springer Science and Business Media LLC; 2012; 32:201-210 10.1007/s10555-012-9401-9
• Influence of fatty acid-free diet on mammary tumor development and growth rate in HER-2/neu transgenic mice Cite
  Rossini A, Zanobbio L, Sfondrini L, Cavalleri A, Secreto G, Morelli D, et al. Influence of fatty acid-free diet on mammary tumor development and growth rate in HER-2/neu transgenic mice. Journal of Cellular Physiology. Wiley; 2012; 228:242-249 10.1002/jcp.24130
• Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids Cite
  Gibson R, Neumann M, Lien E, Boyd K, Tu W. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2013; 88:139-146 10.1016/j.plefa.2012.04.003
• Fatigue, Inflammation, and ω-3 and ω-6 Fatty Acid Intake Among Breast Cancer Survivors Cite
  Alfano CM, Imayama I, Neuhouser ML, Kiecolt-Glaser JK, Smith AW, Meeske K, et al. Fatigue, Inflammation, and ω-3 and ω-6 Fatty Acid Intake Among Breast Cancer Survivors. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2012; 30:1280-1287 10.1200/jco.2011.36.4109
• Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis Cite
  Wen Z, Su Y, Lai P, Zhang Y, Xu Y, Zhao A, et al. Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis. Oncogene. Springer Science and Business Media LLC; 2012; 32:160-170 10.1038/onc.2012.47
• A maternal high n-6 fat diet with fish oil supplementation during pregnancy and lactation in rats decreases breast cancer risk in the female offspring Cite
  Su H, Hsieh P, Chen H. A maternal high n-6 fat diet with fish oil supplementation during pregnancy and lactation in rats decreases breast cancer risk in the female offspring. The Journal of Nutritional Biochemistry. Elsevier BV; 2010; 21:1033-1037 10.1016/j.jnutbio.2009.08.007
• ω-3 and ω-6 Polyunsaturated Fatty Acid Intakes and the Risk of Breast Cancer in Mexican Women: Impact of Obesity Status Cite
  Chajès V, Torres-Mejía G, Biessy C, Ortega-Olvera C, Angeles-Llerenas A, Ferrari P, et al. ω-3 and ω-6 Polyunsaturated Fatty Acid Intakes and the Risk of Breast Cancer in Mexican Women: Impact of Obesity Status. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2011; 21:319-326 10.1158/1055-9965.epi-11-0896
• Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Cite
  Manni A. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. International Journal of Oncology. Spandidos Publications; 2011; 10.3892/ijo.2011.1133
• Abstract 5578: Transcriptomic changes in tamoxifen-treated mammary tumors in Sprague-Dawley rats fed with omega-3 or omega-6 rich diets Cite
  Bidinotto LT, Vanegas JE, Vanden Heuvel JP, de Cicco RL, Santucci-Pereira J, Washington S, et al. Abstract 5578: Transcriptomic changes in tamoxifen-treated mammary tumors in Sprague-Dawley rats fed with omega-3 or omega-6 rich diets. Prevention Research. American Association for Cancer Research; 2011; 10.1158/1538-7445.am2011-5578
• Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy Cite
  Nodari S, Triggiani M, Campia U, Manerba A, Milesi G, Cesana BM, et al. Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy. Journal of the American College of Cardiology. Elsevier BV; 2011; 57:870-879 10.1016/j.jacc.2010.11.017
• Combination of Intermittent Calorie Restriction and Eicosapentaenoic Acid for Inhibition of Mammary Tumors Cite
  Mizuno NK, Rogozina OP, Seppanen CM, Liao DJ, Cleary MP, Grossmann ME. Combination of Intermittent Calorie Restriction and Eicosapentaenoic Acid for Inhibition of Mammary Tumors. Cancer Prevention Research. American Association for Cancer Research (AACR); 2013; 6:540-547 10.1158/1940-6207.capr-13-0033
• Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study Cite
  Murff HJ, Shu X, Li H, Yang G, Wu X, Cai H, et al. Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study. International Journal of Cancer. Wiley; 2010; 128:1434-1441 10.1002/ijc.25703
• Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis Cite
  Manna S, Janarthan M, Ghosh B, Rana B, Rana A, Chatterjee M. Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis. Clinical Nutrition. Elsevier BV; 2010; 29:531-537 10.1016/j.clnu.2009.12.012
• Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21Ras signaling and the proliferation-apoptosis balance Cite
  Solanas M, Grau L, Moral R, Vela E, Escrich R, Escrich E. Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21Ras signaling and the proliferation-apoptosis balance. Carcinogenesis. Oxford University Press (OUP); 2009; 31:871-879 10.1093/carcin/bgp243
• Abstract 229: Omega-3 fattyacids strongly induce apoptosis in human breast cancer cells in vitro and in vivo via formation of reactive oxygen species and caspase 8 activation Cite
  Wang P, Kang K, Yamabe N, Fukui M, Jay T, Zhu BT. Abstract 229: Omega-3 fattyacids strongly induce apoptosis in human breast cancer cells in vitro and in vivo via formation of reactive oxygen species and caspase 8 activation. Cellular and Molecular Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-229
• Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science Cite
  Iyengar NM, Hudis CA, Gucalp A. Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science. Current Breast Cancer Reports. Springer Science and Business Media LLC; 2013; 5:247-254 10.1007/s12609-013-0112-1
• Abstract 2873: Elucidation of dietary omega-6/omega-3 ratio effects on chemopreventive activity using mammographic density as a surrogate marker in rats Cite
  Zhu Z, McGinley JN, Jiang W, Manni A, El-Bayoumy K, Thompson HJ. Abstract 2873: Elucidation of dietary omega-6/omega-3 ratio effects on chemopreventive activity using mammographic density as a surrogate marker in rats. Prevention Research. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-2873
• Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring Cite
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