Tag: omega6

Omega-6 (n-6): A type of essential polyunsaturated fatty acid. Vegetable oils high in linoleic acid (corn oil, safflower oil, soybean oil) are the most abundant source of omega-6 fatty acids. However, omega-6 fats are also found in nuts and seeds, whole grains, certain vegetables and meat.

News

12/08/20: Linoleic acid furthers angiogenesis of triple negative breast cancer
11/04/18: Omega-3 fats reduce tumor growth and increase survival in mice
05/07/17: Vegetable oil linoleic acid promotes migration & invasion of TN cells
04/16/16: Some factors promoting breast cancer metastasis
06/27/15: High corn oil diet promotes mammary tumor development in animal model
03/08/15: Low omega-3 to omega-6 ratio linked to increased BC risk
03/24/14: Common omega-6 fat promotes metastasis of TN breast cancer cells
11/30/12: Fish fats reduce BC risk whereas some other types of fat increase it
09/12/11: Fish oil reduces breast cancer risk by depleting arachidonic acid
12/08/10: Intermittent calorie restriction plus fish oil help prevent BC
05/19/10: Omega-6 rich corn oil reduces effectiveness of tamoxifen

Foods

Studies

Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: a population-based cohort study in UK Biobank Cite
Zhang Y, Sun Y, Song S, Khankari NK, Brenna JT, Shen Y, et al. Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: a population-based cohort study in UK Biobank. Cold Spring Harbor Laboratory; 2024; 10.1101/2024.01.21.24301568
Chemical Compositions and Essential Fatty Acid Analysis of Selected Vegetable Oils and Fats Cite
Ojha PK, Poudel DK, Rokaya A, Maharjan S, Timsina S, Poudel A, et al. Chemical Compositions and Essential Fatty Acid Analysis of Selected Vegetable Oils and Fats. Compounds. MDPI AG; 2024; 4:37-70 10.3390/compounds4010003
High linoleic acid levels in red blood cells predict a poor response to neoadjuvant chemotherapy in HER2-positive breast cancer patients Cite
Valenzuela R, Walbaum B, Farias C, Acevedo F, Vargas C, Bennett JT, et al. High linoleic acid levels in red blood cells predict a poor response to neoadjuvant chemotherapy in HER2-positive breast cancer patients. Nutrition. Elsevier BV; 2024;:112357 10.1016/j.nut.2024.112357
New Insights into Prospective Health Potential of ω-3 PUFAs Cite
Lakshimi VI, Kavitha M. New Insights into Prospective Health Potential of ω-3 PUFAs. Current Nutrition Reports. Springer Science and Business Media LLC; 2023; 10.1007/s13668-023-00508-6
Dietary Omega-6/Omega-3 Polyunsaturated Fatty Acid (PUFA) and Omega-3 Are Associated With General and Abdominal Obesity in Adults: UK National Diet and Nutritional Survey Cite
Albar SA. Dietary Omega-6/Omega-3 Polyunsaturated Fatty Acid (PUFA) and Omega-3 Are Associated With General and Abdominal Obesity in Adults: UK National Diet and Nutritional Survey. Cureus. Cureus, Inc.; 2022; 10.7759/cureus.30209
Association of dietary intake of n-3 polyunsaturated fatty acids with breast cancer risk in pre- and postmenopausal Chinese women Cite
Zhang Z, Ho SC, Liu K, Mo X, Feng X, Li L, et al. Association of dietary intake of n-3 polyunsaturated fatty acids with breast cancer risk in pre- and postmenopausal Chinese women. Menopause. Ovid Technologies (Wolters Kluwer Health); 2022; 29:932-943 10.1097/gme.0000000000001990
Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators Cite
Ouldamer L, Jourdan M, Pinault M, Arbion F, Goupille C. Accumulation of Arachidonic Acid, Precursor of Pro-Inflammatory Eicosanoids, in Adipose Tissue of Obese Women: Association with Breast Cancer Aggressiveness Indicators. Biomedicines. MDPI AG; 2022; 10:995 10.3390/biomedicines10050995
Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells Cite
Biswas P, Datta C, Rathi P, Bhattacharjee A. Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells. Prostaglandins & Other Lipid Mediators. Elsevier BV; 2022;:106637 10.1016/j.prostaglandins.2022.106637
Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels–A systematic review. Cite
Mantzioris E, Muhlhausler BS, Villani A. Impact of the Mediterranean Dietary pattern on n-3 fatty acid tissue levels–A systematic review.. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2022; 176:102387 10.1016/j.plefa.2021.102387
Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids Cite
Luo H, Chen C, Li X, Zhang X, Su C, Liu Y, et al. Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids. STEM CELLS. Wiley; 2021; 10.1002/stem.3452
Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy Cite
Ormiston K, Gaudier-Diaz MM, TinKai T, Fitzgerald J, Cole RM, Andridge R, et al. Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy. Nutritional Neuroscience. Informa UK Limited; 2021;:1-9 10.1080/1028415x.2021.1998296
Role of Src/FAK in migration and invasion mediated by extracellular vesicles from MDA-MB-231 cells stimulated with linoleic acid Cite
Ramirez-Ricardo J, Leal-Orta E, Garcia-Hernandez A, Diaz-Aragon R, Cortes-Reynosa P, Thompson-Bonilla R, et al. Role of Src/FAK in migration and invasion mediated by extracellular vesicles from MDA-MB-231 cells stimulated with linoleic acid. Medical Oncology. Springer Science and Business Media LLC; 2021; 38 10.1007/s12032-021-01485-y
The central role of mitochondria in the relationship between dietary lipids and cancer progression Cite
Varela-López A, Vera-Ramírez L, Giampieri F, Navarro-Hortal MD, Forbes-Hernández TY, Battino M, et al. The central role of mitochondria in the relationship between dietary lipids and cancer progression. Seminars in Cancer Biology. Elsevier BV; 2021; 10.1016/j.semcancer.2021.01.001
Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids Cite
Hillyer LM, Hucik B, Baracuhy EM, Lin Z, Muller WJ, Robinson LE, et al. Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids. Nutrients. MDPI AG; 2020; 12:3901 10.3390/nu12123901
Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells Cite
Diaz-Aragon R, Ramirez-Ricardo J, Cortes-Reynosa P, Simoni-Nieves A, Gomez-Quiroz L, Perez Salazar E. Role of phospholipase D in migration and invasion induced by linoleic acid in breast cancer cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2019; 457:119-132 10.1007/s11010-019-03517-8
Altered Levels of Desaturation and ω-6 Fatty Acids in Breast Cancer Patients’ Red Blood Cell Membranes Cite
Amézaga J, Ugartemendia G, Larraioz A, Bretaña N, Iruretagoyena A, Camba J, et al. Altered Levels of Desaturation and ω-6 Fatty Acids in Breast Cancer Patients’ Red Blood Cell Membranes. Metabolites. MDPI AG; 2020; 10:469 10.3390/metabo10110469
Effects of diets high in corn oil or in extra virgin olive oil on oxidative stress in an experimental model of breast cancer Cite
Escrich R, Vela E, Solanas M, Moral R. Effects of diets high in corn oil or in extra virgin olive oil on oxidative stress in an experimental model of breast cancer. Molecular Biology Reports. Springer Science and Business Media LLC; 2020; 47:4923-4932 10.1007/s11033-020-05492-6
Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population – a Case-Control Study Cite
DYDJOW-BENDEK D, ZAGOŹDŹON P. Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population – a Case-Control Study. In Vivo. Anticancer Research USA Inc.; 2019; 34:423-431 10.21873/invivo.11791
A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways Cite
Escrich R, Costa I, Moreno M, Cubedo M, Vela E, Escrich E, et al. A high-corn-oil diet strongly stimulates mammary carcinogenesis, while a high-extra-virgin-olive-oil diet has a weak effect, through changes in metabolism, immune system function and proliferation/apoptosis pathways. The Journal of Nutritional Biochemistry. Elsevier BV; 2019; 64:218-227 10.1016/j.jnutbio.2018.11.001
Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival Cite
Khadge S, Thiele GM, Sharp JG, McGuire TR, Klassen LW, Black PN, et al. Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival. Clinical & Experimental Metastasis. Springer Science and Business Media LLC; 2018; 35:797-818 10.1007/s10585-018-9941-7
Biomarker of long-chain n-3 fatty acid intake and breast cancer: Accumulative evidence from an updated meta-analysis of epidemiological studies Cite
Yang B, Ren XL, Wang ZY, Wang L, Zhao F, Guo XJ, et al. Biomarker of long-chain n-3 fatty acid intake and breast cancer: Accumulative evidence from an updated meta-analysis of epidemiological studies. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2018; 59:3152-3164 10.1080/10408398.2018.1485133
Linoleic acid induces an increased response to insulin in MDA‐MB‐231 breast cancer cells Cite
Rodriguez‐Monterrosas C, Diaz‐Aragon R, Cortes‐Reynosa P, Salazar EP. Linoleic acid induces an increased response to insulin in MDA‐MB‐231 breast cancer cells. Journal of Cellular Biochemistry. Wiley; 2018; 119:5413-5425 10.1002/jcb.26694
Abstract 5374: Polyunsaturated fatty acids (PUFAs) alter the epigenetic landscape in MDA-MB-231 triple negative breast carcinoma (TNBC) Cite
Chattin AM, O'Brien M, Pardini RS. Abstract 5374: Polyunsaturated fatty acids (PUFAs) alter the epigenetic landscape in MDA-MB-231 triple negative breast carcinoma (TNBC). Molecular and Cellular Biology, Genetics. American Association for Cancer Research; 2017; 10.1158/1538-7445.am2017-5374
Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice Cite
Nguyen NM, de Oliveira Andrade F, Jin L, Zhang X, Macon M, Cruz MI, et al. Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice. Breast Cancer Research. Springer Science and Business Media LLC; 2017; 19 10.1186/s13058-017-0866-x
The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells Cite
Hejr H, Ghareghani M, Zibara K, Ghafari M, Sadri F, Salehpour Z, et al. The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells. Neuroscience Letters. Elsevier BV; 2017; 651:216-225 10.1016/j.neulet.2017.05.020
Linoleic acid induces migration and invasion through FFAR4- and PI3K-/Akt-dependent pathway in MDA-MB-231 breast cancer cells Cite
Serna-Marquez N, Diaz-Aragon R, Reyes-Uribe E, Cortes-Reynosa P, Salazar EP. Linoleic acid induces migration and invasion through FFAR4- and PI3K-/Akt-dependent pathway in MDA-MB-231 breast cancer cells. Medical Oncology. Springer Science and Business Media LLC; 2017; 34 10.1007/s12032-017-0969-3
Fatty acid intake and erythrocyte fatty acid profile in women with breast, ovarian and cervical cancers Cite
Bannikoppa P, Dhayanand J, Madhukumar R, Padmanabhan A, Bafna U, Vijayakumar M, et al. Fatty acid intake and erythrocyte fatty acid profile in women with breast, ovarian and cervical cancers. Clinical Nutrition ESPEN. Elsevier BV; 2017; 19:59-63 10.1016/j.clnesp.2017.03.001
Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland Cite
Manzanares MÁ, de Miguel C, Ruiz de Villa MC, Santella RM, Escrich E, Solanas M. Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland. The Journal of Nutritional Biochemistry. Elsevier BV; 2017; 43:68-77 10.1016/j.jnutbio.2017.01.016
Abstract 4536: Polyunsaturated fatty acids alter the epigenetic landscape in triple-negative breast cancer (TNBC) Cite
Chattin AM, O’Brien M, Pardini RS. Abstract 4536: Polyunsaturated fatty acids alter the epigenetic landscape in triple-negative breast cancer (TNBC). Molecular and Cellular Biology, Genetics. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-4536
Content of Crude Protein, Fixed Oil and Lecithin in Sudanese Seed Accessions of Fenugreek (Trigonella foenum-graecum L.) Cite
Bashir NAO, Elhussein SA, Taha AA. Content of Crude Protein, Fixed Oil and Lecithin in Sudanese Seed Accessions of Fenugreek (Trigonella foenum-graecum L.). Pakistan Journal of Nutrition. Science Alert; 2015; 14:907-912 10.3923/pjn.2015.907.912
Polyunsaturated fatty acid interactions and breast cancer incidence: a population-based case-control study on Long Island, New York Cite
Khankari NK, Bradshaw PT, Steck SE, He K, Olshan AF, Shen J, et al. Polyunsaturated fatty acid interactions and breast cancer incidence: a population-based case-control study on Long Island, New York. Annals of Epidemiology. Elsevier BV; 2015; 25:929-935 10.1016/j.annepidem.2015.09.003
Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231 Cite
Mansara PP, Deshpande RA, Vaidya MM, Kaul-Ghanekar R. Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0136542 10.1371/journal.pone.0136542
Omega-3 and Omega-6 Fatty Acids in Blood and Breast Tissue of High-Risk Women and Association with Atypical Cytomorphology Cite
Hidaka BH, Li S, Harvey KE, Carlson SE, Sullivan DK, Kimler BF, et al. Omega-3 and Omega-6 Fatty Acids in Blood and Breast Tissue of High-Risk Women and Association with Atypical Cytomorphology. Cancer Prevention Research. American Association for Cancer Research (AACR); 2015; 8:359-364 10.1158/1940-6207.capr-14-0351
A high-fat diet rich in corn oil reduces spontaneous locomotor activity and induces insulin resistance in mice Cite
Wong CK, Botta A, Pither J, Dai C, Gibson WT, Ghosh S. A high-fat diet rich in corn oil reduces spontaneous locomotor activity and induces insulin resistance in mice. The Journal of Nutritional Biochemistry. Elsevier BV; 2015; 26:319-326 10.1016/j.jnutbio.2014.11.004
A Higher Dietary Ratio of Long-Chain Omega-3 to Total Omega-6 Fatty Acids for Prevention of COX-2-Dependent Adenocarcinomas Cite
DiNicolantonio JJ, McCarty MF, Chatterjee S, Lavie CJ, O’Keefe JH. A Higher Dietary Ratio of Long-Chain Omega-3 to Total Omega-6 Fatty Acids for Prevention of COX-2-Dependent Adenocarcinomas. Nutrition and Cancer. Informa UK Limited; 2014; 66:1279-1284 10.1080/01635581.2014.956262
Fatty acid profiles, meat quality, and sensory attributes of organic versus conventional dairy beef steers Cite
Bjorklund E, Heins B, DiCostanzo A, Chester-Jones H. Fatty acid profiles, meat quality, and sensory attributes of organic versus conventional dairy beef steers. Journal of Dairy Science. American Dairy Science Association; 2014; 97:1828-1834 10.3168/jds.2013-6984
Impact of grass/forage feeding versus grain finishing on beef nutrients and sensory quality: The U.S. experience Cite
Van Elswyk ME, McNeill SH. Impact of grass/forage feeding versus grain finishing on beef nutrients and sensory quality: The U.S. experience. Meat Science. Elsevier BV; 2014; 96:535-540 10.1016/j.meatsci.2013.08.010
Prospective Associations between Plasma Saturated, Monounsaturated and Polyunsaturated Fatty Acids and Overall and Breast Cancer Risk – Modulation by Antioxidants: A Nested Case-Control Study Cite
Pouchieu C, Chajès V, Laporte F, Kesse-Guyot E, Galan P, Hercberg S, et al. Prospective Associations between Plasma Saturated, Monounsaturated and Polyunsaturated Fatty Acids and Overall and Breast Cancer Risk – Modulation by Antioxidants: A Nested Case-Control Study. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e90442 10.1371/journal.pone.0090442
Arachidonic acid promotes migration and invasion through a PI3K/Akt-dependent pathway in MDA-MB-231 breast cancer cells Cite
Villegas-Comonfort S, Castillo-Sanchez R, Serna-Marquez N, Cortes-Reynosa P, Salazar EP. Arachidonic acid promotes migration and invasion through a PI3K/Akt-dependent pathway in MDA-MB-231 breast cancer cells. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2014; 90:169-177 10.1016/j.plefa.2014.01.007
Relations of omega-3 and omega-6 intake with mammographic breast density Cite
Diorio C, Dumas I. Relations of omega-3 and omega-6 intake with mammographic breast density. Cancer Causes & Control. Springer Science and Business Media LLC; 2014; 25:339-351 10.1007/s10552-013-0335-5
Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort Cite
Olsen KS, Fenton C, Frøyland L, Waaseth M, Paulssen RH, Lund E. Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e67270 10.1371/journal.pone.0067270
Erythrocyte Omega-6 and Omega-3 Fatty Acids and Mammographic Breast Density Cite
Hudson AG, Reeves KW, Modugno F, Wilson JW, Evans RW, Vogel VG, et al. Erythrocyte Omega-6 and Omega-3 Fatty Acids and Mammographic Breast Density. Nutrition and Cancer. Informa UK Limited; 2013; 65:410-416 10.1080/01635581.2013.760744
Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue Cite
Pender-Cudlip MC, Krag KJ, Martini D, Yu J, Guidi A, Skinner SS, et al. Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue. Cancer Science. Wiley; 2013; 104:760-764 10.1111/cas.12129
Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells Cite
Serna-Marquez N, Villegas-Comonfort S, Galindo-Hernandez O, Navarro-Tito N, Millan A, Salazar EP. Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. Cellular Oncology. Springer Science and Business Media LLC; 2012; 36:65-77 10.1007/s13402-012-0114-4
Dietary Intake of Specific Fatty Acids and Breast Cancer Risk Among Postmenopausal Women in the VITAL Cohort Cite
Sczaniecka AK, Brasky TM, Lampe JW, Patterson RE, White E. Dietary Intake of Specific Fatty Acids and Breast Cancer Risk Among Postmenopausal Women in the VITAL Cohort. Nutrition and Cancer. Informa UK Limited; 2012; 64:1131-1142 10.1080/01635581.2012.718033
The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis Cite
Kang JX, Liu A. The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis. Cancer and Metastasis Reviews. Springer Science and Business Media LLC; 2012; 32:201-210 10.1007/s10555-012-9401-9
Influence of fatty acid-free diet on mammary tumor development and growth rate in HER-2/neu transgenic mice Cite
Rossini A, Zanobbio L, Sfondrini L, Cavalleri A, Secreto G, Morelli D, et al. Influence of fatty acid-free diet on mammary tumor development and growth rate in HER-2/neu transgenic mice. Journal of Cellular Physiology. Wiley; 2012; 228:242-249 10.1002/jcp.24130
Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids Cite
Gibson R, Neumann M, Lien E, Boyd K, Tu W. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2013; 88:139-146 10.1016/j.plefa.2012.04.003
Fatigue, Inflammation, and ω-3 and ω-6 Fatty Acid Intake Among Breast Cancer Survivors Cite
Alfano CM, Imayama I, Neuhouser ML, Kiecolt-Glaser JK, Smith AW, Meeske K, et al. Fatigue, Inflammation, and ω-3 and ω-6 Fatty Acid Intake Among Breast Cancer Survivors. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2012; 30:1280-1287 10.1200/jco.2011.36.4109
Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis Cite
Wen Z, Su Y, Lai P, Zhang Y, Xu Y, Zhao A, et al. Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis. Oncogene. Springer Science and Business Media LLC; 2012; 32:160-170 10.1038/onc.2012.47
A maternal high n-6 fat diet with fish oil supplementation during pregnancy and lactation in rats decreases breast cancer risk in the female offspring Cite
Su H, Hsieh P, Chen H. A maternal high n-6 fat diet with fish oil supplementation during pregnancy and lactation in rats decreases breast cancer risk in the female offspring. The Journal of Nutritional Biochemistry. Elsevier BV; 2010; 21:1033-1037 10.1016/j.jnutbio.2009.08.007
ω-3 and ω-6 Polyunsaturated Fatty Acid Intakes and the Risk of Breast Cancer in Mexican Women: Impact of Obesity Status Cite
Chajès V, Torres-Mejía G, Biessy C, Ortega-Olvera C, Angeles-Llerenas A, Ferrari P, et al. ω-3 and ω-6 Polyunsaturated Fatty Acid Intakes and the Risk of Breast Cancer in Mexican Women: Impact of Obesity Status. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2011; 21:319-326 10.1158/1055-9965.epi-11-0896
Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Cite
Manni A. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. International Journal of Oncology. Spandidos Publications; 2011; 10.3892/ijo.2011.1133
Abstract 5578: Transcriptomic changes in tamoxifen-treated mammary tumors in Sprague-Dawley rats fed with omega-3 or omega-6 rich diets Cite
Bidinotto LT, Vanegas JE, Vanden Heuvel JP, de Cicco RL, Santucci-Pereira J, Washington S, et al. Abstract 5578: Transcriptomic changes in tamoxifen-treated mammary tumors in Sprague-Dawley rats fed with omega-3 or omega-6 rich diets. Prevention Research. American Association for Cancer Research; 2011; 10.1158/1538-7445.am2011-5578
Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy Cite
Nodari S, Triggiani M, Campia U, Manerba A, Milesi G, Cesana BM, et al. Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy. Journal of the American College of Cardiology. Elsevier BV; 2011; 57:870-879 10.1016/j.jacc.2010.11.017
Combination of Intermittent Calorie Restriction and Eicosapentaenoic Acid for Inhibition of Mammary Tumors Cite
Mizuno NK, Rogozina OP, Seppanen CM, Liao DJ, Cleary MP, Grossmann ME. Combination of Intermittent Calorie Restriction and Eicosapentaenoic Acid for Inhibition of Mammary Tumors. Cancer Prevention Research. American Association for Cancer Research (AACR); 2013; 6:540-547 10.1158/1940-6207.capr-13-0033
Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study Cite
Murff HJ, Shu X, Li H, Yang G, Wu X, Cai H, et al. Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study. International Journal of Cancer. Wiley; 2010; 128:1434-1441 10.1002/ijc.25703
Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis Cite
Manna S, Janarthan M, Ghosh B, Rana B, Rana A, Chatterjee M. Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis. Clinical Nutrition. Elsevier BV; 2010; 29:531-537 10.1016/j.clnu.2009.12.012
Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21Ras signaling and the proliferation-apoptosis balance Cite
Solanas M, Grau L, Moral R, Vela E, Escrich R, Escrich E. Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21Ras signaling and the proliferation-apoptosis balance. Carcinogenesis. Oxford University Press (OUP); 2009; 31:871-879 10.1093/carcin/bgp243
Abstract 229: Omega-3 fattyacids strongly induce apoptosis in human breast cancer cells in vitro and in vivo via formation of reactive oxygen species and caspase 8 activation Cite
Wang P, Kang K, Yamabe N, Fukui M, Jay T, Zhu BT. Abstract 229: Omega-3 fattyacids strongly induce apoptosis in human breast cancer cells in vitro and in vivo via formation of reactive oxygen species and caspase 8 activation. Cellular and Molecular Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-229
Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science Cite
Iyengar NM, Hudis CA, Gucalp A. Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science. Current Breast Cancer Reports. Springer Science and Business Media LLC; 2013; 5:247-254 10.1007/s12609-013-0112-1
Abstract 2873: Elucidation of dietary omega-6/omega-3 ratio effects on chemopreventive activity using mammographic density as a surrogate marker in rats Cite
Zhu Z, McGinley JN, Jiang W, Manni A, El-Bayoumy K, Thompson HJ. Abstract 2873: Elucidation of dietary omega-6/omega-3 ratio effects on chemopreventive activity using mammographic density as a surrogate marker in rats. Prevention Research. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-2873
Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring Cite
Ion G, Akinsete JA, Hardman WE. Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. BMC Cancer. Springer Science and Business Media LLC; 2010; 10 10.1186/1471-2407-10-81
Long-Chain n-3-to-n-6 Polyunsaturated Fatty Acid Ratios in Breast Adipose Tissue From Women With and Without Breast Cancer Cite
Bagga D, Anders KH, Wang H, Glaspy JA. Long-Chain n-3-to-n-6 Polyunsaturated Fatty Acid Ratios in Breast Adipose Tissue From Women With and Without Breast Cancer. Nutrition and Cancer. Informa UK Limited; 2002; 42:180-185 10.1207/s15327914nc422_5
5-Lipoxygenase and 5-Lipoxygenase-Activating Protein Gene Polymorphisms, Dietary Linoleic Acid, and Risk for Breast Cancer Cite
Wang J, John EM, Ingles SA. 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein Gene Polymorphisms, Dietary Linoleic Acid, and Risk for Breast Cancer. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2008; 17:2748-2754 10.1158/1055-9965.epi-08-0439
Dietary intakes of ω-6 and ω-3 polyunsaturated fatty acids and the risk of breast cancer Cite
Thiébaut AC, Chajès V, Gerber M, Boutron-Ruault M, Joulin V, Lenoir G, et al. Dietary intakes of ω-6 and ω-3 polyunsaturated fatty acids and the risk of breast cancer. International Journal of Cancer. Wiley; 2009; 124:924-931 10.1002/ijc.23980
N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France Cite
Maillard V, Bougnoux P, Ferrari P, Jourdan M, Pinault M, Lavillonnière F, et al. N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France. International Journal of Cancer. Wiley; 2001; 98:78-83 10.1002/ijc.10130
Opposing effects of dietary n-3 and n-6 fatty acids on mammary carcinogenesis: The Singapore Chinese Health Study Cite
Gago-Dominguez M, Yuan J, Sun C, Lee H, Yu MC. Opposing effects of dietary n-3 and n-6 fatty acids on mammary carcinogenesis: The Singapore Chinese Health Study. British Journal of Cancer. Springer Science and Business Media LLC; 2003; 89:1686-1692 10.1038/sj.bjc.6601340
Lipid Composition and Contaminants in Farmed and Wild Salmon Cite
Hamilton MC, Hites RA, Schwager SJ, Foran JA, Knuth BA, Carpenter DO. Lipid Composition and Contaminants in Farmed and Wild Salmon. Environmental Science & Technology. American Chemical Society (ACS); 2005; 39:8622-8629 10.1021/es050898y
The Content of Favorable and Unfavorable Polyunsaturated Fatty Acids Found in Commonly Eaten Fish Cite
Weaver KL, Ivester P, Chilton JA, Wilson MD, Pandey P, Chilton FH. The Content of Favorable and Unfavorable Polyunsaturated Fatty Acids Found in Commonly Eaten Fish. Journal of the American Dietetic Association. Elsevier BV; 2008; 108:1178-1185 10.1016/j.jada.2008.04.023
Canola Oil Inhibits Breast Cancer Cell Growth in Cultures and In Vivo and Acts Synergistically with Chemotherapeutic Drugs Cite
Cho K, Mabasa L, Fowler AW, Walsh DM, Park CS. Canola Oil Inhibits Breast Cancer Cell Growth in Cultures and In Vivo and Acts Synergistically with Chemotherapeutic Drugs. Lipids. Wiley; 2010; 45:777-784 10.1007/s11745-010-3462-8
Fatty acid uptake by breast cancer cells (MDA-MB-231): Effects of insulin, leptin, adiponectin, and TNFα Cite
Kaur B, Jørgensen A, Duttaroy AK. Fatty acid uptake by breast cancer cells (MDA-MB-231): Effects of insulin, leptin, adiponectin, and TNFα. Prostaglandins, Leukotrienes and Essential Fatty Acids. Elsevier BV; 2009; 80:93-99 10.1016/j.plefa.2009.01.002
Dietary (n-3)/(n-6) Fatty Acid Ratio: Possible Relationship to Premenopausal but Not Postmenopausal Breast Cancer Risk in U.S. Women Cite
Goodstine SL, Zheng T, Holford TR, Ward BA, Carter D, Owens PH, et al. Dietary (n-3)/(n-6) Fatty Acid Ratio: Possible Relationship to Premenopausal but Not Postmenopausal Breast Cancer Risk in U.S. Women. The Journal of Nutrition. Oxford University Press (OUP); 2003; 133:1409-1414 10.1093/jn/133.5.1409
Exogenous supplementation with ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells Cite
Menendez JA, Lupu R, Colomer R. Exogenous supplementation with ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2005; 14:263-270 10.1097/00008469-200506000-00011