Tag: ellagicAcid

News

01/04/16

Walnut compounds have chemopreventive actions

02/28/15

Ellagic acid in pomegranates and berries inhibits ER+/PR+ growth

10/05/14

Walnut compounds impair BC energy supply and induce cell death

02/26/14

Ellagic acid reduces proliferation of ER+/PR+ breast cancer cells

10/17/12

Pomegranate juice inhibits metastatic processes in BC cells

03/03/12

Breast cancer blood vessel formation is blocked by ellagic acid

05/14/10

Blueberries and black raspberries prevent mammary tumors in rats

01/05/10

Pomegranate compounds inhibit aromatase and reduces proliferation

Foods

• • blackberries
  • boysenberries
  • grapes
  • pomegranates
  • raspberries
  • strawberries
  • walnuts

Studies

• Urolithin a inhibits breast cancer progression via activating TFEB-mediated mitophagy in tumor macrophages Cite
  Zheng B, Wang Y, Zhou B, Qian F, Liu D, Ye D, et al. Urolithin a inhibits breast cancer progression via activating TFEB-mediated mitophagy in tumor macrophages. Journal of Advanced Research. Elsevier BV; 2024; 10.1016/j.jare.2024.04.010
• Berries vs. Disease: Revenge of the Phytochemicals Cite
  Lamenza FF, Upadhaya P, Roth P, Shrestha S, Jagadeesha S, Horn N, et al. Berries vs. Disease: Revenge of the Phytochemicals. Pharmaceuticals. MDPI AG; 2024; 17:84 10.3390/ph17010084
• Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence Cite
  Čižmáriková M, Michalková R, Mirossay L, Mojžišová G, Zigová M, Bardelčíková A, et al. Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence. Biomolecules. MDPI AG; 2023; 13:1653 10.3390/biom13111653
• Diagnostic biomarker of ellagic acid compound from pomegranate plant punica granatum) on receptor protein-tyrosine kinase ERBB-2 in identifying breast cancer Cite
  Syamsurizal S, Zainul R, Novel D, Verawati R, Lubis A, Mandeli R, et al. Diagnostic biomarker of ellagic acid compound from pomegranate plant punica granatum) on receptor protein-tyrosine kinase ERBB-2 in identifying breast cancer. Journal of Medicinal and Pharmaceutical Chemistry Research. Sami Publishing Company (SPC); 2023; 10.48309/jmpcr.2023.417770.1009
• Rubus Occidentalis and its bioactive compounds against cancer: from molecular mechanisms to translational advances Cite
  Wang G, Su H, Guo Z, Li H, Jiang Z, Cao Y, et al. Rubus Occidentalis and its bioactive compounds against cancer: from molecular mechanisms to translational advances. Phytomedicine. Elsevier BV; 2023;:155029 10.1016/j.phymed.2023.155029
• A Review of the Dietary Intake, Bioavailability and Health Benefits of Ellagic Acid (EA) with a Primary Focus on Its Anti-Cancer Properties Cite
  Harper P. A Review of the Dietary Intake, Bioavailability and Health Benefits of Ellagic Acid (EA) with a Primary Focus on Its Anti-Cancer Properties. Cureus. Springer Science and Business Media LLC; 2023; 10.7759/cureus.43156
• Ellagic Acid - A Dietary Polyphenol with Anticancer Activity that Deserves More Consideration Cite
  Djaldetti M. Ellagic Acid - A Dietary Polyphenol with Anticancer Activity that Deserves More Consideration. Recent Progress in Nutrition. LIDSEN Publishing Inc; 2023; 03:1-32 10.21926/rpn.2303011
• The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art Cite
  Lu G, Wang X, Cheng M, Wang S, Ma K. The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 165:115132 10.1016/j.biopha.2023.115132
• An Overview of the Health Benefits, Extraction Methods and Improving the Properties of Pomegranate Cite
  Benedetti G, Zabini F, Tagliavento L, Meneguzzo F, Calderone V, Testai L. An Overview of the Health Benefits, Extraction Methods and Improving the Properties of Pomegranate. Antioxidants. MDPI AG; 2023; 12:1351 10.3390/antiox12071351
• Urolithin A: A promising selective estrogen receptor modulator and 27‐hydroxycholesterol attenuator in breast cancer Cite
  Vini R, Jaikumar VS, Remadevi V, Ravindran S, Azeez JM, Sasikumar A, et al. Urolithin A: A promising selective estrogen receptor modulator and 27‐hydroxycholesterol attenuator in breast cancer. Phytotherapy Research. Wiley; 2023; 10.1002/ptr.7919
• Bioactive compounds and health benefits of pomegranate: An updated narrative review Cite
  Cheng J, Li J, Xiong R, Wu S, Huang S, Zhou D, et al. Bioactive compounds and health benefits of pomegranate: An updated narrative review. Food Bioscience. Elsevier BV; 2023; 53:102629 10.1016/j.fbio.2023.102629
• The Therapeutic Alliance between Pomegranate and Health Emphasizing on Anticancer Properties Cite
  Pantiora PD, Balaouras AI, Mina IK, Freris CI, Pappas AC, Danezis GP, et al. The Therapeutic Alliance between Pomegranate and Health Emphasizing on Anticancer Properties. Antioxidants. MDPI AG; 2023; 12:187 10.3390/antiox12010187
• Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties Cite
  Zeeshan Bhatti M, Ismail H, Khan Kayani W. Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties. Secondary Metabolites - Trends and Reviews [Working Title]. IntechOpen; 2022; 10.5772/intechopen.103698
• Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association Cite
  Javaid A, Zahra D, Rashid F, Mashraqi M, Alzamami A, Khurshid M, et al. Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association. Saudi Journal of Biological Sciences. Elsevier BV; 2022; 10.1016/j.sjbs.2022.03.005
• Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential Cite
  Sharifi-Rad J, Quispe C, Castillo CMS, Caroca R, Lazo-Vélez MA, Antonyak H, et al. Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential. Oxidative Medicine and Cellular Longevity. Hindawi Limited; 2022; 2022:1-24 10.1155/2022/3848084
• Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment Cite
  Xue P, Zhang G, Zhang J, Ren L. Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment. Phytomedicine. Elsevier BV; 2022; 99:153998 10.1016/j.phymed.2022.153998
• Dietary Ellagitannins Cite
  Sadeer NB, Mahomoodally MF, Rengasamy KRR. Dietary Ellagitannins. Handbook of Dietary Phytochemicals. Springer Singapore; 2021;:1145-1171 10.1007/978-981-15-4148-3_25
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Ellagic acid-loaded, tween 80-coated, chitosan nanoparticles as a promising therapeutic approach against breast cancer: In-vitro and in-vivo study Cite
  Kaur H, Ghosh S, Kumar P, Basu B, Nagpal K. Ellagic acid-loaded, tween 80-coated, chitosan nanoparticles as a promising therapeutic approach against breast cancer: In-vitro and in-vivo study. Life Sciences. Elsevier BV; 2021;:119927 10.1016/j.lfs.2021.119927
• Study of Transferability of Rubus Microsatellite Markers to Hybrid Boysenberry Cite
  Ryu J, Kim WJ, Im J, Kim SH, Oh SC, Cho L, et al. Study of Transferability of Rubus Microsatellite Markers to Hybrid Boysenberry. Plant Breeding and Biotechnology. Korean Society of Breeding Science; 2017; 5:253-260 10.9787/pbb.2017.5.4.253
• Modulatory impact of selected ellagitannins on the viability of human breast cancer cells Cite
  Berdowska I, Zieliński B, Saczko J, Sopel M, Gamian A, Fecka I. Modulatory impact of selected ellagitannins on the viability of human breast cancer cells. Journal of Functional Foods. Elsevier BV; 2018; 42:122-128 10.1016/j.jff.2017.12.053
• Ellagic acid in strawberry (Fragaria spp.): Biological, technological, stability, and human health aspects Cite
  Muthukumaran S, Tranchant C, Shi J, Ye X, Xue SJ. Ellagic acid in strawberry (Fragaria spp.): Biological, technological, stability, and human health aspects. Food Quality and Safety. Oxford University Press (OUP); 2017; 1:227-252 10.1093/fqsafe/fyx023
• Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats Cite
  Rizk HA, Masoud MA, Maher OW. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. Journal of Biochemical and Molecular Toxicology. Wiley; 2017; 31:e21977 10.1002/jbt.21977
• Aqueous extract from pecan nut [Carya illinoinensis (Wangenh) C. Koch] shell show activity against breast cancer cell line MCF-7 and Ehrlich ascites tumor in Balb-C mice Cite
  Hilbig J, Policarpi PdB, Grinevicius VMAdS, Mota NSRS, Toaldo IM, Luiz MTB, et al. Aqueous extract from pecan nut [Carya illinoinensis (Wangenh) C. Koch] shell show activity against breast cancer cell line MCF-7 and Ehrlich ascites tumor in Balb-C mice. Journal of Ethnopharmacology. Elsevier BV; 2018; 211:256-266 10.1016/j.jep.2017.08.012
• Abstract 1912: Actn4, a novel therapeutic target of dietary ellagic acid, promotes breast cancer metastasisviamediating cancer stem cells Cite
  Wang N, Wang Z, Xie X. Abstract 1912: Actn4, a novel therapeutic target of dietary ellagic acid, promotes breast cancer metastasisviamediating cancer stem cells. Tumor Biology. American Association for Cancer Research; 2017; 10.1158/1538-7445.am2017-1912
• Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis Cite
  Srivastava S, Somasagara RR, Hegde M, Nishana M, Tadi SK, Srivastava M, et al. Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis. Scientific Reports. Springer Science and Business Media LLC; 2016; 6 10.1038/srep24049
• Health benefits of walnut polyphenols: An exploration beyond their lipid profile Cite
  Sánchez-González C, Ciudad CJ, Noé V, Izquierdo-Pulido M. Health benefits of walnut polyphenols: An exploration beyond their lipid profile. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2017; 57:3373-3383 10.1080/10408398.2015.1126218
• Ellagic acid induces cell cycle arrest and apoptosis through TGF-β/Smad3 signaling pathway in human breast cancer MCF-7 cells Cite
  CHEN H, BAI M, ZHANG T, LI G, LIU M. Ellagic acid induces cell cycle arrest and apoptosis through TGF-β/Smad3 signaling pathway in human breast cancer MCF-7 cells. International Journal of Oncology. Spandidos Publications; 2015; 46:1730-1738 10.3892/ijo.2015.2870
• In vitro bioactivities and phytochemical profile of various parts of the strawberry (Fragaria × ananassa var. Amaou) Cite
  Zhu Q, Nakagawa T, Kishikawa A, Ohnuki K, Shimizu K. In vitro bioactivities and phytochemical profile of various parts of the strawberry (Fragaria × ananassa var. Amaou). Journal of Functional Foods. Elsevier BV; 2015; 13:38-49 10.1016/j.jff.2014.12.026
• Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells Cite
  Le V, Esposito D, Grace MH, Ha D, Pham A, Bortolazzo A, et al. Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells. Nutrition and Cancer. Informa UK Limited; 2014; 66:1304-1314 10.1080/01635581.2014.956246
• Ellagic Acid Exerts Anti-proliferation Effects via Modulation of Tgf-Β/Smad3 Signaling in MCF-7 Breast Cancer Cells Cite
  Zhang T, Chen H, Wang L, Bai M, Wang Y, Jiang X, et al. Ellagic Acid Exerts Anti-proliferation Effects via Modulation of Tgf-Β/Smad3 Signaling in MCF-7 Breast Cancer Cells. Asian Pacific Journal of Cancer Prevention. Asian Pacific Organization for Cancer Prevention; 2014; 15:273-276 10.7314/apjcp.2014.15.1.273
• Anticancer effects of bioactive berry compounds Cite
  Folmer F, Basavaraju U, Jaspars M, Hold G, El-Omar E, Dicato M, et al. Anticancer effects of bioactive berry compounds. Phytochemistry Reviews. Springer Science and Business Media LLC; 2013; 13:295-322 10.1007/s11101-013-9319-z
• The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP) Cite
  González-Sarrías A, Miguel V, Merino G, Lucas R, Morales JC, Tomás-Barberán F, et al. The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2013; 61:4352-4359 10.1021/jf4007505
• Strawberry As a Functional Food: An Evidence-Based Review Cite
  Basu A, Nguyen A, Betts NM, Lyons TJ. Strawberry As a Functional Food: An Evidence-Based Review. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2013; 54:790-806 10.1080/10408398.2011.608174
• Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines Cite
  Woode DR, Aiyer HS, Sie N, Zwart AL, Li L, Seeram NP, et al. Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines. International Journal of Breast Cancer. Hindawi Limited; 2012; 2012:1-11 10.1155/2012/147828
• Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2) Cite
  Tan KW, Li Y, Paxton JW, Birch NP, Scheepens A. Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2). Food Chemistry. Elsevier BV; 2013; 138:2267-2274 10.1016/j.foodchem.2012.12.021
• Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer Cite
  Rocha A, Wang L, Penichet M, Martins-Green M. Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 136:647-658 10.1007/s10549-012-2264-5
• Inhibition of Estrogen-Mediated Mammary Tumorigenesis by Blueberry and Black Raspberry Cite
  Ravoori S, Vadhanam MV, Aqil F, Gupta RC. Inhibition of Estrogen-Mediated Mammary Tumorigenesis by Blueberry and Black Raspberry. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:5547-5555 10.1021/jf205325p
• Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) α+β+ transcript in estrogen receptor-positive MCF-7 breast cancer cells Cite
  Strati A, Papoutsi Z, Lianidou E, Moutsatsou P. Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) α+β+ transcript in estrogen receptor-positive MCF-7 breast cancer cells. Clinical Biochemistry. Elsevier BV; 2009; 42:1358-1362 10.1016/j.clinbiochem.2009.05.017
• Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer Cite
  Wang N, Wang Z, Mo S, Loo TY, Wang D, Luo H, et al. Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 134:943-955 10.1007/s10549-012-1977-9
• Tumor Angiogenesis as a Target for Dietary Cancer Prevention Cite
  Li WW, Li VW, Hutnik M, Chiou AS. Tumor Angiogenesis as a Target for Dietary Cancer Prevention. Journal of Oncology. Hindawi Limited; 2012; 2012:1-23 10.1155/2012/879623
• Chemoprevention of mammary carcinogenesis by sustained systemic delivery of ellagic acid Cite
  Vadhanam MV, Ravoori S, Aqil F, Gupta RC. Chemoprevention of mammary carcinogenesis by sustained systemic delivery of ellagic acid. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2011; 20:484-491 10.1097/cej.0b013e3283498e00
• Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention Cite
  Aiyer HS, Warri AM, Woode DR, Hilakivi-Clarke L, Clarke R. Influence of Berry Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:5693-5708 10.1021/jf204084f
• The Blackberry Fruit: A Review on Its Composition and Chemistry, Metabolism and Bioavailability, and Health Benefits Cite
  Kaume L, Howard LR, Devareddy L. The Blackberry Fruit: A Review on Its Composition and Chemistry, Metabolism and Bioavailability, and Health Benefits. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2011; 60:5716-5727 10.1021/jf203318p
• Berries and Ellagic Acid Prevent Estrogen-Induced Mammary Tumorigenesis by Modulating Enzymes of Estrogen Metabolism Cite
  Aiyer HS, Gupta RC. Berries and Ellagic Acid Prevent Estrogen-Induced Mammary Tumorigenesis by Modulating Enzymes of Estrogen Metabolism. Cancer Prevention Research. American Association for Cancer Research (AACR); 2010; 3:727-737 10.1158/1940-6207.capr-09-0260
• Identification of Flavonoid and Phenolic Antioxidants in Black Currants, Blueberries, Raspberries, Red Currants, and Cranberries† Cite
  Borges G, Degeneve A, Mullen W, Crozier A. Identification of Flavonoid and Phenolic Antioxidants in Black Currants, Blueberries, Raspberries, Red Currants, and Cranberries†. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2010; 58:3901-3909 10.1021/jf902263n
• Abstract 1887: Distinct molecular targets of blueberry and black raspberry in breast cancer prevention Cite
  Ravoori S, Kausar H, Aqil F, Gupta RC. Abstract 1887: Distinct molecular targets of blueberry and black raspberry in breast cancer prevention. Prevention Research. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-1887
• Pomegranate Ellagitannin–Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro Cite
  Adams LS, Zhang Y, Seeram NP, Heber D, Chen S. Pomegranate Ellagitannin–Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro. Cancer Prevention Research. American Association for Cancer Research (AACR); 2010; 3:108-113 10.1158/1940-6207.capr-08-0225
• Dietary Berries and Ellagic Acid Diminish Estrogen-Mediated Mammary Tumorigenesis ∈ ACI rats Cite
  Aiyer H, Srinivasan C, Gupta R. Dietary Berries and Ellagic Acid Diminish Estrogen-Mediated Mammary Tumorigenesis ∈ ACI rats. Nutrition and Cancer. Informa UK Limited; 2008; 60:227-234 10.1080/01635580701624712
• Beware of Pomegranates Bearing 40% Ellagic Acid Cite
  Lansky EP. Beware of Pomegranates Bearing 40% Ellagic Acid. Journal of Medicinal Food. Mary Ann Liebert Inc; 2006; 9:119-122 10.1089/jmf.2006.9.119
• Antioxidant Activity and Phenolic Content of Oregon Caneberries Cite
  Wada L, Ou B. Antioxidant Activity and Phenolic Content of Oregon Caneberries. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2002; 50:3495-3500 10.1021/jf011405l
• Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry Extracts Inhibit Growth and Stimulate Apoptosis of Human Cancer Cells In Vitro Cite
  Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, et al. Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry Extracts Inhibit Growth and Stimulate Apoptosis of Human Cancer Cells In Vitro. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2006; 54:9329-9339 10.1021/jf061750g