Tag: taxane
Taxane: A type of chemotherapy drug that inhibits cancer cell division (mitosis). Examples include paclitaxel and docetaxel. Taxanes interfere with the functioning of microtubules, which help move chromosomes during mitosis.
Articles
News
03/12/17
Broccoli compound sulforaphane heightens taxane chemotherapy effectiveness against triple negative breast cancer 02/18/17
Scalp cooling can prevent hair loss caused by chemotherapy 02/22/12
Selenium increases effectiveness of Taxol chemotherapy for triple negative breast cancer 01/17/12
Apigenin increases effectiveness of Taxol chemotherapy 12/07/11
Modern chemotherapy reduces breast cancer death by about a third compared to no chemotherapy 10/27/11
The beta blocker propranolol increases the effectiveness of Taxol 10/06/11
Non-anthracycline chemotherapy plus Herceptin is effective treatment for HER2+ breast cancer 09/22/11
Herceptin has reduced locoregional recurrence for HER2+ compared to triple negative breast cancer 12/26/10
Muscle and joint pain are common during taxane chemotherapy for breast cancer 12/20/10
Brassica compound DIM inhibits breast cancer cell growth synergistically with Taxotere 11/08/10
Response to neoadjuvant chemotherapy depends on dosage and tumor type 04/14/10
Predictors of failure to respond to neoadjuvant chemotherapy
Studies
Risk of incident claims for chemotherapy‐induced peripheral neuropathy among women with breast cancer in a Medicare population Associations between self-reported diet during treatment and chemotherapy-induced peripheral neuropathy in a cooperative group trial COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy Permanent Chemotherapy‐Induced Alopecia in Patients with Breast Cancer: A 3‐Year Prospective Cohort Study Efficacy of scalp cooling in reducing alopecia in early breast cancer patients receiving contemporary chemotherapy regimens Cucurbitacin D enhances the therapeutic efficacy of docetaxel via targeting cancer stem cells and miR-145 Incidence of long-term hair loss (LHL) following docetaxel (D)-containing non-anthracycline (A) adjuvant chemotherapy (Adj) of early stage breast cancer (ESB) Carotenoid Lutein Selectively Inhibits Breast Cancer Cell Growth and Potentiates the Effect of Chemotherapeutic Agents through ROS-Mediated Mechanisms Taxane acute pain syndrome (TAPS) in patients receiving chemotherapy for breast or prostate cancer: a prospective multi-center study Long-term peripheral neuropathy symptoms in breast cancer survivors Tunicamycin potentiates paclitaxel-induced apoptosis through inhibition of PI3K/AKT and MAPK pathways in breast cancer Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy Two-year trends of taxane-induced neuropathy in women enrolled in a randomized trial of acetyl-l-carnitine Role of taxanes in chemotherapy-related cognitive impairment: A prospective longitudinal study Chemotherapy-induced irreversible alopecia in early breast cancer patients Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers Permanent alopecia in patients with breast cancer after taxane chemotherapy and adjuvant hormonal therapy: Clinicopathologic findings in a cohort of 10 patients Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells Enhanced oral bioavailability of docetaxel in rats combined with myricetin: In situ and in vivo evidences A Difference in the Incidences of Hypersensitivity Reactions to Original and Generic Taxanes Scalp cooling alopecia prevention trial (SCALP) for patients with early stage breast cancer BMI, Lifestyle Factors and Taxane-Induced Neuropathy in Breast Cancer Patients: The Pathways Study Factors associated with ovarian function recovery after chemotherapy for breast cancer: a systematic review and meta-analysis A randomised, placebo-controlled trial assessing the efficacy of an oral B group vitamin in preventing the development of chemotherapy-induced peripheral neuropathy (CIPN) Evaluation of the effect of compression therapy using surgical gloves on nanoparticle albumin-bound paclitaxel-induced peripheral neuropathy: a phase II multicenter study by the Kamigata Breast Cancer Study Group Taxane acute pain syndrome (TAPS) in patients receiving taxane-based chemotherapy for breast cancer—a systematic review Anthracycline-Free Neoadjuvant Chemotherapy Ensures Higher Rates of Pathologic Complete Response in Breast Cancer A prospective study on the neurological complications of breast cancer and its treatment: Updated analysis three years after cancer diagnosis Ferulic acid reverses ABCB1-mediated paclitaxel resistance in MDR cell lines Randomized sham-controlled pilot trial of weekly electro-acupuncture for the prevention of taxane-induced peripheral neuropathy in women with early stage breast cancer Effectiveness of an Adjuvant Chemotherapy Regimen for Early-Stage Breast Cancer A Systematic Review and Network Meta-analysis Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2-Akt axis Synergistic Apoptotic Effect of Crocin and Paclitaxel or Crocin and Radiation on MCF-7 Cells, a Type of Breast Cancer Cell Line The challenge of preserving cardiorespiratory fitness in physically inactive patients with colon or breast cancer during adjuvant chemotherapy: a randomised feasibility study Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model Improving therapeutic efficacy of Docetaxel in breast cancer Adjuvant taxanes and the development of breast cancer-related arm lymphoedema Taxane induced neuropathy in patients affected by breast cancer: literature review One-tenth of patients younger than 40 years develop a permanent chemotherapy-induced ovarian function failure after receiving adjuvant anthracycline-based chemotherapy with or without taxanes Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage Selective Carotenoid Growth Inhibition in Breast Cancer: Independence of Hormonal Sensitivity Prevalence of BRCA1 mutations and responses to neoadjuvant chemotherapy among BRCA1 carriers and non-carriers with triple-negative breast cancer Impact of body mass index on neoadjuvant treatment outcome: a pooled analysis of eight prospective neoadjuvant breast cancer trials Docetaxel-induced neuropathy: A pharmacogenetic case-control study of 150 women with early-stage breast cance Clinical Practice Guidelines on the Use of Integrative Therapies as Supportive Care in Patients Treated for Breast Cancer Resveratrol Augments Paclitaxel Treatment in MDA-MB-231 and Paclitaxel-resistant MDA-MB-231 Breast Cancer Cells Treatment factors affecting breast cancer-related lymphedema after systemic chemotherapy and radiotherapy in stage II/III breast cancer patients Risk of Hospitalization According to Chemotherapy Regimen in Early-Stage Breast Cancer Long-term survivor characteristics in HER2-positive metastatic breast cancer from registHER Pathological complete response after neoadjuvant chemotherapy is an independent predictive factor irrespective of simplified breast cancer intrinsic subtypes: a landmark and two-step approach analyses from the EORTC 10994/BIG 1-00 phase III trial Thymoquinone, A Bioactive Component of Black Caraway Seeds, Causes G1 Phase Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells with Mutant p53 Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled analysis Changes in body weight during various types of chemotherapy in breast cancer patients Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels Risk of docetaxel-induced peripheral neuropathy among 1,725 Danish patients with early stage breast cancer A Survey of Joint and Muscle Aches, Pain, and Stiffness Comparing Women With and Without Breast Cancer Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy Metabolomics Reveals Metabolic Targets and Biphasic Responses in Breast Cancer Cells Treated by Curcumin Alone and in Association with Docetaxel The depletion of Interleukin-8 causes cell cycle arrest and increases the efficacy of docetaxel in breast cancer cells The triterpenoid cucurbitacin B augments the anti-proliferative activity of chemotherapy in human breast cancer Peripheral neuropathies from chemotherapeutics and targeted agents: diagnosis, treatment, and prevention Neuropathy Is Not Associated With Clinical Outcomes in Patients Receiving Adjuvant Taxane-Containing Therapy for Operable Breast Cancer Estrogen receptor status confers a distinct pattern of response to neoadjuvant chemotherapy: implications for optimal durations of therapy Mortality, leukemic risk, and cardiovascular toxicity of adjuvant anthracycline and taxane chemotherapy in breast cancer: a meta-analysis Coping with the burden of taste alteration, a toxicity of taxane-based chemotherapy Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-κB Pathway Pre-treatment hormonal receptor status and Ki67 index predict pathologic complete response to neoadjuvant trastuzumab/taxanes but not disease-free survival in HER2-positive breast cancer patients Incidence of reversible amenorrhea in women with breast cancer undergoing adjuvant anthracycline-based chemotherapy with or without docetaxel Incidence of chemotherapy-induced amenorrhea in hormone-sensitive breast cancer patients: the impact of addition of taxanes to anthracycline-based regimens Longer Therapy, Iatrogenic Amenorrhea, and Survival in Early Breast Cancer Incidence of reduced chemotherapy relative dose intensity among women with early stage breast cancer in US clinical practice Predictive role of molecular subtypes in response to neoadjuvant chemotherapy in breast cancer patients in northeast china Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials Paclitaxel-induced peripheral neuropathy in patients receiving adjuvant chemotherapy for breast cancer Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro Adjuvant Trastuzumab in HER2-Positive Breast Cancer Efficacy of neoadjuvant therapy with trastuzumab concurrent with anthracycline- and nonanthracycline-based regimens for HER2-positive breast cancer Responsiveness of adjacent ductal carcinoma in situ and changes in HER2 status after neoadjuvant chemotherapy/trastuzumab treatment in early breast cancer: Results from the GeparQuattro study (GBG 40) Comparison of locoregional recurrence in triple-negative and HER2-positive breast cancer subtype after breast-conserving therapy and modern systemic therapy Body mass index (BMI) and prognosis in women with metastatic breast cancer (MBC) Outcomes of inflammatory versus noninflammatory T4 breast cancers in the age of taxanes and trastuzumab Muscle and Joint Symptoms in Breast Cancer Patients Receiving Taxane-Based Chemotherapy Impact of treatment characteristics on response of different breast cancer phenotypes: pooled analysis of the German neo-adjuvant chemotherapy trials Hematologic toxicity with adjuvant docetaxel and cyclophosphamide in early breast cancer Late pancreatic toxicity in patients with breast cancer after taxane-anthracycline-based neoadjuvant and adjuvant chemotherapy Hepatotoxicity in breast cancer patients post-chemotherapy with docetaxel, doxorubucin, and cyclophosphamide Differential response from neoadjuvant chemotherapy across breast cancer subtypes Prognostic Significance of Neutropenia on Day One of Anthracycline-Based Neoadjuvant Chemotherapy in Operable Breast Cancer 3, 3'-diindolylmethane enhances taxotere-induced growth inhibition of breast cancer cells through down-regulation of FoxM1 Decrease in breast density in the contralateral normal breast of patients receiving neoadjuvant chemotherapy: MR imaging evaluation Predictors of Tumor Progression During Neoadjuvant Chemotherapy in Breast Cancer Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer Fifteen-year trends in metastatic breast cancer survival in Greece Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo Exogenous supplementation with [omega]-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane Influence of Garlic (Allium sativum) on the Pharmacokinetics of Docetaxel
TOP