Tag: sulforaphane

Articles

• Supplements with warnings for breast cancer

News

03/12/17

Sulforaphane in broccoli heightens taxane effects against TN disease

05/23/15

Sulforaphane inhibits HER2+ and triple negative breast cancer

06/29/14

Arugula compound erucin inhibits proliferation of ER+ BC cells

11/05/12

Frozen broccoli has less bioavailable sulforaphane than fresh broccoli

02/20/12

Cruciferous vegetable consumption linked to reduced risk of cancer

12/18/11

Isothiocyanates have genotoxic potential at concentrated doses

04/18/10

Broccoli compound sulforaphane reduces BC stem cell survival

Foods

• • broccoli
  • brussels sprouts
  • cabbage
  • cauliflower
  • greens
  • horseradish
  • kale
  • watercress

Studies

• Sulforaphane—A Compound with Potential Health Benefits for Disease Prevention and Treatment: Insights from Pharmacological and Toxicological Experimental Studies Cite
  Baralić K, Živanović J, Marić Đ, Bozic D, Grahovac L, Antonijević Miljaković E, et al. Sulforaphane—A Compound with Potential Health Benefits for Disease Prevention and Treatment: Insights from Pharmacological and Toxicological Experimental Studies. Antioxidants. MDPI AG; 2024; 13:147 10.3390/antiox13020147
• Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review Cite
  Sailo BL, Liu L, Chauhan S, Girisa S, Hegde M, Liang L, et al. Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review. Cancers. MDPI AG; 2024; 16:244 10.3390/cancers16020244
• Glucosinolates in cancer prevention and treatment: experimental and clinical evidence Cite
  Orouji N, Asl SK, Taghipour Z, Habtemariam S, Nabavi SM, Rahimi R. Glucosinolates in cancer prevention and treatment: experimental and clinical evidence. Medical Oncology. Springer Science and Business Media LLC; 2023; 40 10.1007/s12032-023-02211-6
• Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer Cite
  da Silva FC, Brandão DC, Ferreira EA, Siqueira RP, Ferreira HSV, Da Silva Filho AA, et al. Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer. Pharmaceuticals. MDPI AG; 2023; 16:1466 10.3390/ph16101466
• A review on anti-nutritional factors: unraveling the natural gateways to human health Cite
  Salim R, Nehvi IB, Mir RA, Tyagi A, Ali S, Bhat OM. A review on anti-nutritional factors: unraveling the natural gateways to human health. Frontiers in Nutrition. Frontiers Media SA; 2023; 10 10.3389/fnut.2023.1215873
• Phytochemicals Modify the Action of Cancer Cells Mitochondrial Drug-Resistance Mechanism Cite
  Das S. Phytochemicals Modify the Action of Cancer Cells Mitochondrial Drug-Resistance Mechanism. Sciences of Pharmacy. Etflin; 2023; 2:79-105 10.58920/sciphar02030079
• Anticancer activity of broccoli, its organosulfur and polyphenolic compounds Cite
  Gasmi A, Gasmi Benahmed A, Shanaida M, Chirumbolo S, Menzel A, Anzar W, et al. Anticancer activity of broccoli, its organosulfur and polyphenolic compounds. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2023;:1-19 10.1080/10408398.2023.2195493
• Sulforaphane-Induced Cell Mitotic Delay and Inhibited Cell Proliferation via Regulating CDK5R1 Upregulation in Breast Cancer Cell Lines Cite
  Hung C, Tsai T, Lee K, Hsu Y. Sulforaphane-Induced Cell Mitotic Delay and Inhibited Cell Proliferation via Regulating CDK5R1 Upregulation in Breast Cancer Cell Lines. Biomedicines. MDPI AG; 2023; 11:996 10.3390/biomedicines11040996
• Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model Cite
  Pogorzelska A, Mazur M, Świtalska M, Wietrzyk J, Sigorski D, Fronczyk K, et al. Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 161:114490 10.1016/j.biopha.2023.114490
• Glucosinolate Biosynthetic Genes of Cabbage: Genome-Wide Identification, Evolution, and Expression Analysis Cite
  Wang P, Cao W, Yang L, Zhang Y, Fang Z, Zhuang M, et al. Glucosinolate Biosynthetic Genes of Cabbage: Genome-Wide Identification, Evolution, and Expression Analysis. Genes. MDPI AG; 2023; 14:476 10.3390/genes14020476
• Dietary Isothiocyanates: Novel Insights into the Potential for Cancer Prevention and Therapy Cite
  Na G, He C, Zhang S, Tian S, Bao Y, Shan Y. Dietary Isothiocyanates: Novel Insights into the Potential for Cancer Prevention and Therapy. International Journal of Molecular Sciences. MDPI AG; 2023; 24:1962 10.3390/ijms24031962
• The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2—A Systematic Review Cite
  Krejbich P, Birringer M. The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2—A Systematic Review. Antioxidants. MDPI AG; 2022; 11:2149 10.3390/antiox11112149
• Anti-adipogenic effects of sulforaphane-rich ingredient with broccoli sprout and mustard seed in 3T3-L1 preadipocytes Cite
  Men X, Han X, Lee S, Park K, Han J, Choi S, et al. Anti-adipogenic effects of sulforaphane-rich ingredient with broccoli sprout and mustard seed in 3T3-L1 preadipocytes. Planta Medica. Georg Thieme Verlag KG; 2022; 10.1055/a-1853-7101
• Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition Cite
  Sharma M, Tollefsbol TO. Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. Experimental Cell Research. Elsevier BV; 2022; 416:113160 10.1016/j.yexcr.2022.113160
• Sulfur compounds: From plants to humans and their role in chronic disease prevention Cite
  Hill CR, Shafaei A, Balmer L, Lewis JR, Hodgson JM, Millar AH, et al. Sulfur compounds: From plants to humans and their role in chronic disease prevention. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2022;:1-23 10.1080/10408398.2022.2057915
• Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway Cite
  Zhang Y, Lu Q, Li N, Xu M, Miyamoto T, Liu J. Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway. npj Breast Cancer. Springer Science and Business Media LLC; 2022; 8 10.1038/s41523-022-00402-4
• Sulforaphane: The Principal Broccoli Phytochemical as a Cancer Challenger Cite
  Djaldetti M. Sulforaphane: The Principal Broccoli Phytochemical as a Cancer Challenger. Recent Progress in Nutrition. LIDSEN Publishing Inc; 2022; 2:1-1 10.21926/rpn.2201008
• Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association Cite
  Javaid A, Zahra D, Rashid F, Mashraqi M, Alzamami A, Khurshid M, et al. Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association. Saudi Journal of Biological Sciences. Elsevier BV; 2022; 10.1016/j.sjbs.2022.03.005
• Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity Cite
  Janczewski Ł. Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity. Molecules. MDPI AG; 2022; 27:1750 10.3390/molecules27051750
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis Cite
  Maroni P, Bendinelli P, Fulgenzi A, Ferraretto A. Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis. Biomolecules. MDPI AG; 2021; 11:1336 10.3390/biom11091336
• Sulforaphane attenuates cisplatin-induced hearing loss by inhibiting histone deacetylase expression Cite
  Wang J, Tian K, Fang Y, Chang H, Han Y, Chen F. Sulforaphane attenuates cisplatin-induced hearing loss by inhibiting histone deacetylase expression. International Journal of Immunopathology and Pharmacology. SAGE Publications; 2021; 35:205873842110340 10.1177/20587384211034086
• Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy Cite
  Sabo AA, Dudau M, Constantin GL, Pop TC, Geilfus C, Naccarati A, et al. Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy. Frontiers in Pharmacology. Frontiers Media SA; 2021; 12 10.3389/fphar.2021.652074
• Cytokine Secretions in Partial Breast Tumor Microenvironment With and Without Sulforaphane Cite
  Merrick C, Housley L. Cytokine Secretions in Partial Breast Tumor Microenvironment With and Without Sulforaphane. Current Developments in Nutrition. Oxford University Press (OUP); 2021; 5:274-274 10.1093/cdn/nzab036_016
• Studies on exogenous elicitors promotion of sulforaphane content in broccoli sprouts and its effect on the MDA-MB-231 breast cancer cell line Cite
  Amer MA, Mohamed TR, Abdel Rahman RA, Ali M, Badr A. Studies on exogenous elicitors promotion of sulforaphane content in broccoli sprouts and its effect on the MDA-MB-231 breast cancer cell line. Annals of Agricultural Sciences. Elsevier BV; 2021; 66:46-52 10.1016/j.aoas.2021.02.001
• Sulforaphane-Cisplatin Combination inhibits the stemness and metastatic potential of TNBCs via down regulation of Sirtuins-mediated EMT signaling axis Cite
  Sinha S, Sharma S, Sharma A, Vora J, Shrivastava N. Sulforaphane-Cisplatin Combination inhibits the stemness and metastatic potential of TNBCs via down regulation of Sirtuins-mediated EMT signaling axis. Phytomedicine. Elsevier BV; 2021;:153492 10.1016/j.phymed.2021.153492
• R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines Cite
  Licznerska B, Szaefer H, Krajka-Kuźniak V. R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2020; 10.1007/s11010-020-03913-5
• Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells Cite
  Rong Y, Huang L, Yi K, Chen H, Liu S, Zhang W, et al. Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells. Cancer Letters. Elsevier BV; 2020; 493:189-196 10.1016/j.canlet.2020.08.041
• Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol Cite
  Palliyaguru DL, Yang L, Chartoumpekis DV, Wendell SG, Fazzari M, Skoko JJ, et al. Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol. Nutrients. MDPI AG; 2020; 12:2282 10.3390/nu12082282
• Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects Cite
  Calcabrini C, Maffei F, Turrini E, Fimognari C. Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects. Frontiers in Pharmacology. Frontiers Media SA; 2020; 11 10.3389/fphar.2020.00567
• Sulforaphane as an anticancer molecule: mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems Cite
  Kamal MM, Akter S, Lin C, Nazzal S. Sulforaphane as an anticancer molecule: mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems. Archives of Pharmacal Research. Springer Science and Business Media LLC; 2020; 43:371-384 10.1007/s12272-020-01225-2
• Histone deacetylase activity and vitamin D‐dependent gene expressions in relation to sulforaphane in human breast cancer cells Cite
  Hossain S, Liu Z, Wood RJ. Histone deacetylase activity and vitamin D‐dependent gene expressions in relation to sulforaphane in human breast cancer cells. Journal of Food Biochemistry. Wiley; 2019; 44 10.1111/jfbc.13114
• Sulforaphane Impacts Invasion Capacity and Proliferation of Triple Negative Breast Cancer Cells Grown in the Presence of Tumor-associated Macrophages (P05-003-19) Cite
  Jensen K, Slattery E, Housley L, Hansen E. Sulforaphane Impacts Invasion Capacity and Proliferation of Triple Negative Breast Cancer Cells Grown in the Presence of Tumor-associated Macrophages (P05-003-19). Current Developments in Nutrition. Oxford University Press (OUP); 2019; 3 10.1093/cdn/nzz030.p05-003-19
• Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells Cite
  Cheng A, Shen C, Hung C, Hsu Y. Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells. Journal of Medicinal Food. Mary Ann Liebert Inc; 2019; 22:444-450 10.1089/jmf.2018.4195
• Combating breast cancer using combination therapy with 3 phytochemicals: Piperine, sulforaphane, and thymoquinone Cite
  Aumeeruddy MZ, Mahomoodally MF. Combating breast cancer using combination therapy with 3 phytochemicals: Piperine, sulforaphane, and thymoquinone. Cancer. Wiley; 2019; 125:1600-1611 10.1002/cncr.32022
• In the triple-negative breast cancer MDA-MB-231 cell line, sulforaphane enhances the intracellular accumulation and anticancer action of doxorubicin encapsulated in liposomes Cite
  Mielczarek L, Krug P, Mazur M, Milczarek M, Chilmonczyk Z, Wiktorska K. In the triple-negative breast cancer MDA-MB-231 cell line, sulforaphane enhances the intracellular accumulation and anticancer action of doxorubicin encapsulated in liposomes. International Journal of Pharmaceutics. Elsevier BV; 2019; 558:311-318 10.1016/j.ijpharm.2019.01.008
• Temporal Efficacy of a Sulforaphane-Based Broccoli Sprout Diet in Prevention of Breast Cancer through Modulation of Epigenetic Mechanisms Cite
  Li Y, Buckhaults P, Li S, Tollefsbol T. Temporal Efficacy of a Sulforaphane-Based Broccoli Sprout Diet in Prevention of Breast Cancer through Modulation of Epigenetic Mechanisms. Cancer Prevention Research. American Association for Cancer Research (AACR); 2018; 11:451-464 10.1158/1940-6207.capr-17-0423
• Potentiation of paclitaxel effect by resveratrol in human breast cancer cells by counteracting the 17β-estradiol/estrogen receptor α/neuroglobin pathway Cite
  Cipolletti M, Montalesi E, Nuzzo MT, Fiocchetti M, Ascenzi P, Marino M. Potentiation of paclitaxel effect by resveratrol in human breast cancer cells by counteracting the 17β-estradiol/estrogen receptor α/neuroglobin pathway. Journal of Cellular Physiology. Wiley; 2018; 234:3147-3157 10.1002/jcp.27309
• Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells Cite
  Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, et al. Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Life Sciences. Elsevier BV; 2018; 213:149-157 10.1016/j.lfs.2018.10.034
• Glucosinolate and isothiocyanate intakes are inversely associated with breast cancer risk: a case–control study in China Cite
  Zhang N, Ho SC, Mo X, Lin F, Huang W, Luo H, et al. Glucosinolate and isothiocyanate intakes are inversely associated with breast cancer risk: a case–control study in China. British Journal of Nutrition. Cambridge University Press (CUP); 2018; 119:957-964 10.1017/s0007114518000600
• Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model Cite
  Bose C, Awasthi S, Sharma R, Beneš H, Hauer-Jensen M, Boerma M, et al. Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. PLOS ONE. Public Library of Science (PLoS); 2018; 13:e0193918 10.1371/journal.pone.0193918
• Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis Cite
  Gianfredi V, Vannini S, Moretti M, Villarini M, Bragazzi NL, Izzotti A, et al. Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis. Journal of Nutrigenetics and Nutrigenomics. S. Karger AG; 2017; 10:126-135 10.1159/000480636
• Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line Cite
  Milczarek M, Wiktorska K, Mielczarek L, Koronkiewicz M, Dąbrowska A, Lubelska K, et al. Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative breast cancer cell line. Food and Chemical Toxicology. Elsevier BV; 2018; 111:1-8 10.1016/j.fct.2017.10.056
• Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties Cite
  Hanschen FS, Schreiner M. Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties. Frontiers in Plant Science. Frontiers Media SA; 2017; 8 10.3389/fpls.2017.01095
• Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells Cite
  Pawlik A, Wała M, Hać A, Felczykowska A, Herman-Antosiewicz A. Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells. Phytomedicine. Elsevier BV; 2017; 29:1-10 10.1016/j.phymed.2017.03.007
• Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells Cite
  Burnett JP, Lim G, Li Y, Shah RB, Lim R, Paholak HJ, et al. Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells. Cancer Letters. Elsevier BV; 2017; 394:52-64 10.1016/j.canlet.2017.02.023
• Abstract 2173: Sulforaphane suppresses the growth of triple-negative breast cancer stem cells in vitro and in vivo Cite
  Castro NP, Rangel MC, Merchant AS, Saylor K, Salomon D, Kim Y. Abstract 2173: Sulforaphane suppresses the growth of triple-negative breast cancer stem cells in vitro and in vivo. Cancer Chemistry. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-2173
• Sulforaphene inhibits triple negative breast cancer through activating tumor suppressor Egr1 Cite
  Yang M, Teng W, Qu Y, Wang H, Yuan Q. Sulforaphene inhibits triple negative breast cancer through activating tumor suppressor Egr1. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 158:277-286 10.1007/s10549-016-3888-7
• Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling Cite
  Bao C, Kim MC, Chen J, Song J, Ko HW, Lee HJ. Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2016; 64:5515-5524 10.1021/acs.jafc.6b02195
• Combination of lapatinib with isothiocyanates overcomes drug resistance and inhibits migration of HER2 positive breast cancer cells Cite
  Kaczyńska A, Herman-Antosiewicz A. Combination of lapatinib with isothiocyanates overcomes drug resistance and inhibits migration of HER2 positive breast cancer cells. Breast Cancer. Springer Science and Business Media LLC; 2016; 24:271-280 10.1007/s12282-016-0700-9
• Associations between cruciferous vegetable intake and selected biomarkers among women scheduled for breast biopsies Cite
  Zhang Z, Atwell LL, Farris PE, Ho E, Shannon J. Associations between cruciferous vegetable intake and selected biomarkers among women scheduled for breast biopsies. Public Health Nutrition. Cambridge University Press (CUP); 2015; 19:1288-1295 10.1017/s136898001500244x
• Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer. Cite
  Burnett J, Korkaya H, Newman B, Conley S, Connarn J, Sun L, et al. Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer.. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2013; 10.1158/1538-7445.am2013-913
• Sulforaphane inhibited tumor necrosis factor-α induced migration and invasion in estrogen receptor negative human breast cancer cells Cite
  Bao C, Ko J, Park H, Kim MC, Kim J, Auh J, et al. Sulforaphane inhibited tumor necrosis factor-α induced migration and invasion in estrogen receptor negative human breast cancer cells. Food Science and Biotechnology. Springer Science and Business Media LLC; 2015; 24:347-351 10.1007/s10068-015-0046-7
• Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition Cite
  Tortorella SM, Royce SG, Licciardi PV, Karagiannis TC. Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition. Antioxidants & Redox Signaling. Mary Ann Liebert Inc; 2015; 22:1382-1424 10.1089/ars.2014.6097
• Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells Cite
  Li Q, Xia J, Yao Y, Gong D, Shi H, Zhou Q. Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 141:317-324 10.1007/s10549-013-2672-1
• Cruciferous vegetables intake is inversely associated with risk of breast cancer: A meta-analysis Cite
  Liu X, Lv K. Cruciferous vegetables intake is inversely associated with risk of breast cancer: A meta-analysis. The Breast. Elsevier BV; 2013; 22:309-313 10.1016/j.breast.2012.07.013
• Sulforaphane inhibits growth of phenotypically different breast cancer cells Cite
  Pawlik A, Wiczk A, Kaczyńska A, Antosiewicz J, Herman-Antosiewicz A. Sulforaphane inhibits growth of phenotypically different breast cancer cells. European Journal of Nutrition. Springer Science and Business Media LLC; 2013; 52:1949-1958 10.1007/s00394-013-0499-5
• Isothiocyanate concentrations and interconversion of sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh broccoli Cite
  Saha S, Hollands W, Teucher B, Needs PW, Narbad A, Ortori CA, et al. Isothiocyanate concentrations and interconversion of sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh broccoli. Molecular Nutrition & Food Research. Wiley; 2012; 56:1906-1916 10.1002/mnfr.201200225
• Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage Cite
  Zanichelli F, Capasso S, Di Bernardo G, Cipollaro M, Pagnotta E, Cartenì M, et al. Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage. Apoptosis. Springer Science and Business Media LLC; 2012; 17:964-974 10.1007/s10495-012-0740-3
• Influence of fermentation conditions of Brassica oleracea L. var. capitata on the volatile glucosinolate hydrolysis compounds of sauerkrauts Cite
  Peñas E, Pihlava J, Vidal-Valverde C, Frias J. Influence of fermentation conditions of Brassica oleracea L. var. capitata on the volatile glucosinolate hydrolysis compounds of sauerkrauts. LWT - Food Science and Technology. Elsevier BV; 2012; 48:16-23 10.1016/j.lwt.2012.03.005
• Tumor Angiogenesis as a Target for Dietary Cancer Prevention Cite
  Li WW, Li VW, Hutnik M, Chiou AS. Tumor Angiogenesis as a Target for Dietary Cancer Prevention. Journal of Oncology. Hindawi Limited; 2012; 2012:1-23 10.1155/2012/879623
• Natural isothiocyanates: Genotoxic potential versus chemoprevention Cite
  Fimognari C, Turrini E, Ferruzzi L, Lenzi M, Hrelia P. Natural isothiocyanates: Genotoxic potential versus chemoprevention. Mutation Research/Reviews in Mutation Research. Elsevier BV; 2012; 750:107-131 10.1016/j.mrrev.2011.12.001
• Comparison of Isothiocyanate Metabolite Levels and Histone Deacetylase Activity in Human Subjects Consuming Broccoli Sprouts or Broccoli Supplement Cite
  Clarke JD, Riedl K, Bella D, Schwartz SJ, Stevens JF, Ho E. Comparison of Isothiocyanate Metabolite Levels and Histone Deacetylase Activity in Human Subjects Consuming Broccoli Sprouts or Broccoli Supplement. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2011; 59:10955-10963 10.1021/jf202887c
• Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design Cite
  Clarke JD, Hsu A, Riedl K, Bella D, Schwartz SJ, Stevens JF, et al. Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design. Pharmacological Research. Elsevier BV; 2011; 64:456-463 10.1016/j.phrs.2011.07.005
• Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice Cite
  Tsubura A. Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice. Oncology Reports. Spandidos Publications; 2011; 10.3892/or.2011.1311
• Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption Cite
  Lai R, Miller MJ, Jeffery E. Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption. Food & Function. Royal Society of Chemistry (RSC); 2010; 1:161 10.1039/c0fo00110d
• Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Cite
  Li Y, Zhang T, Korkaya H, Liu S, Lee H, Newman B, et al. Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells. Clinical Cancer Research. American Association for Cancer Research (AACR); 2010; 16:2580-2590 10.1158/1078-0432.ccr-09-2937
• Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines Cite
  Pledgie-Tracy A, Sobolewski MD, Davidson NE. Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines. Molecular Cancer Therapeutics. American Association for Cancer Research (AACR); 2007; 6:1013-1021 10.1158/1535-7163.mct-06-0494
• Dietary Organic Isothiocyanates are Cytotoxic in Human Breast Cancer MCF-7 and Mammary Epithelial MCF-12A Cell Lines Cite
  Tseng E, Ramsay EAS, Morris ME. Dietary Organic Isothiocyanates are Cytotoxic in Human Breast Cancer MCF-7 and Mammary Epithelial MCF-12A Cell Lines. Experimental Biology and Medicine. SAGE Publications; 2004; 229:835-842 10.1177/153537020422900817
• Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells Cite
  Rose P, Huang Q, Ong CN, Whiteman M. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicology and Applied Pharmacology. Elsevier BV; 2005; 209:105-113 10.1016/j.taap.2005.04.010
• Expression profile ofCYP19in human breast cancer cell lines treated with indole-3-carbinol, 3,3'-diindolylmethane, and sulforaphane. Cite
  Licznerska B, Matuszak I, Baer-Dubowska W. Expression profile ofCYP19in human breast cancer cell lines treated with indole-3-carbinol, 3,3'-diindolylmethane, and sulforaphane.. Poster Session Abstracts. American Association for Cancer Research; 2009; 10.1158/0008-5472.sabcs-1113
• Regulation of estrogen receptor α expression in human breast cancer cells by sulforaphane Cite
  Ramirez MC, Singletary K. Regulation of estrogen receptor α expression in human breast cancer cells by sulforaphane. The Journal of Nutritional Biochemistry. Elsevier BV; 2009; 20:195-201 10.1016/j.jnutbio.2008.02.002
• Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane Cite
  Azarenko O, Okouneva T, Singletary KW, Jordan MA, Wilson L. Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane. Carcinogenesis. Oxford University Press (OUP); 2008; 29:2360-2368 10.1093/carcin/bgn241