Tag: ginger

News

03/26/17

Ginger compound induces triple negative breast cancer cell death

02/22/15

Blueberry and ginger compounds enhance Taxol treatment effects

Foods

• • ginger

Studies

• Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors Cite
  Ravindra B. Malabadi , Sadiya MR , Kiran P. Kolkar , Simuzar S. Mammadova , Raju K. Chalannavar , Himansu Baijnath , et al. Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors. Open Access Research Journal of Biology and Pharmacy. Open Access Research Journals Publication; 2024; 10:028-071 10.53022/oarjbp.2024.10.2.0013
• The effect of ginger extract on expression of Gli1 and Patched-1 genes involved in breast cancer signaling pathway under in vitro condition Cite
  Mahsa Torabi S, Rahaie M, Ebrahimi A. The effect of ginger extract on expression of Gli1 and Patched-1 genes involved in breast cancer signaling pathway under in vitro condition. Biomedicine. Indian Association of Biomedical Scientists; 2024; 44:107-113 10.51248/.v44i1.4152
• Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It Cite
  Sheybatzadeh K, Moshtaghie SAA, Shahanipour K, Golab F. Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It. Asian Pacific Journal of Cancer Prevention. EpiSmart Science Vector Ltd; 2024; 25:893-908 10.31557/apjcp.2024.25.3.893
• Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy Cite
  Khan F, Pandey P, Verma M, Ramniwas S, Lee D, Moon S, et al. Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy. Biomedicine & Pharmacotherapy. Elsevier BV; 2024; 173:116363 10.1016/j.biopha.2024.116363
• Nutritional components, phytochemical compositions, biological properties, and potential food applications of ginger (Zingiber officinale): A comprehensive review Cite
  Yang Z, Guo Z, Yan J, Xie J. Nutritional components, phytochemical compositions, biological properties, and potential food applications of ginger (Zingiber officinale): A comprehensive review. Journal of Food Composition and Analysis. Elsevier BV; 2024;:106057 10.1016/j.jfca.2024.106057
• Preparation and Characterization of Chitosan-Coated Nanostructured Lipid Carriers (CS-NLC) Containing (6)-Gingerol and Investigating their Toxicity Against MCF-7 Breast Cancer Cell Line Cite
  Al-Ziyadi RKM, Hayati N, Rezaei MR, Es-haghi A. Preparation and Characterization of Chitosan-Coated Nanostructured Lipid Carriers (CS-NLC) Containing (6)-Gingerol and Investigating their Toxicity Against MCF-7 Breast Cancer Cell Line. BioNanoScience. Springer Science and Business Media LLC; 2023; 10.1007/s12668-023-01261-4
• Anticancer perspective of 6-shogaol: anticancer properties, mechanism of action, synergism and delivery system Cite
  Jia Y, Li X, Meng X, Lei J, Xia Y, Yu L. Anticancer perspective of 6-shogaol: anticancer properties, mechanism of action, synergism and delivery system. Chinese Medicine. Springer Science and Business Media LLC; 2023; 18 10.1186/s13020-023-00839-0
• Ginger exosome-like nanoparticles (GELNs) induced apoptosis, cell cycle arrest, and anti-metastatic effects in triple-negative breast cancer MDA-mb-231 cells Cite
  Anusha R, Ashin M, Priya S. Ginger exosome-like nanoparticles (GELNs) induced apoptosis, cell cycle arrest, and anti-metastatic effects in triple-negative breast cancer MDA-mb-231 cells. Food and Chemical Toxicology. Elsevier BV; 2023;:114102 10.1016/j.fct.2023.114102
• Deciphering the anticancer, anti-inflammatory and antioxidant potential of Ti nanoparticles fabricated using Zingiber officinale Cite
  Anh Nga NT, Sathiyavimal S, A. Al-Humaid L, Al- Dahmash ND, Lee J, Barathi S, et al. Deciphering the anticancer, anti-inflammatory and antioxidant potential of Ti nanoparticles fabricated using Zingiber officinale. Environmental Research. Elsevier BV; 2023;:116748 10.1016/j.envres.2023.116748
• A comprehensive review on Ginger (Zingiber officinale) as a potential source of nutraceuticals for food formulations: Towards the polishing of gingerol and other present biomolecules Cite
  Garza-Cadena C, Ortega-Rivera DM, Machorro-García G, Gonzalez-Zermeño EM, Homma-Dueñas D, Plata-Gryl M, et al. A comprehensive review on Ginger (Zingiber officinale) as a potential source of nutraceuticals for food formulations: Towards the polishing of gingerol and other present biomolecules. Food Chemistry. Elsevier BV; 2023; 413:135629 10.1016/j.foodchem.2023.135629
• Fabrication, optimization, and characterization of pH-responsive PEGylated nanoniosomes containing gingerol for enhanced treatment of breast cancer Cite
  Asghari Lalami Z, Tafvizi F, Naseh V, Salehipour M. Fabrication, optimization, and characterization of pH-responsive PEGylated nanoniosomes containing gingerol for enhanced treatment of breast cancer. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2023; 10.1007/s00210-023-02579-2
• Evaluation of the Herb–Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents Cite
  Husain I, Dale OR, Idrisi M, Gurley BJ, Avula B, Katragunta K, et al. Evaluation of the Herb–Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2023; 71:7521-7534 10.1021/acs.jafc.2c07912
• An investigation into the effects of 6-Gingerol on glucose and glutamine metabolism in breast cancer cell lines Cite
  Ghorbani M, Shafiee SM, Dianati-Nassab A, Behbahani SE, Honardar Z, Khoshdel Z. An investigation into the effects of 6-Gingerol on glucose and glutamine metabolism in breast cancer cell lines. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2707034/v1
• Ginger-Derived 3HDT Exerts Antiproliferative Effects on Breast Cancer Cells by Apoptosis and DNA Damage Cite
  Chen C, Chen Y, Shiau J, Tang J, Hou M, Chang H. Ginger-Derived 3HDT Exerts Antiproliferative Effects on Breast Cancer Cells by Apoptosis and DNA Damage. International Journal of Molecular Sciences. MDPI AG; 2023; 24:5741 10.3390/ijms24065741
• 10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling Cite
  Liang Y, Wu G, Luo T, Xie H, Zuo Q, Huang P, et al. 10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling. Drug Design, Development and Therapy. Informa UK Limited; 2023; Volume 17:129-142 10.2147/dddt.s390602
• A review of the pharmacodynamic effect of chemo-herbal drug combinations therapy for cancer treatment Cite
  Okem A, Henstra C, Lambert M, Hayeshi R. A review of the pharmacodynamic effect of chemo-herbal drug combinations therapy for cancer treatment. Medicine in Drug Discovery. Elsevier BV; 2023; 17:100147 10.1016/j.medidd.2022.100147
• Bioactive Compounds from the Zingiberaceae Family with Known Antioxidant Activities for Possible Therapeutic Uses Cite
  Alolga RN, Wang F, Zhang X, Li J, Tran LP, Yin X. Bioactive Compounds from the Zingiberaceae Family with Known Antioxidant Activities for Possible Therapeutic Uses. Antioxidants. MDPI AG; 2022; 11:1281 10.3390/antiox11071281
• Zingiberene exerts chemopreventive activity against 7,12‐dimethylbenz(a)anthracene‐induced breast cancer in Sprague‐Dawley rats Cite
  Seshadri VD, Oyouni AAA, Bawazir WM, Alsagaby SA, Alsharif KF, Albrakati A, et al. Zingiberene exerts chemopreventive activity against 7,12‐dimethylbenz(a)anthracene‐induced breast cancer in Sprague‐Dawley rats. Journal of Biochemical and Molecular Toxicology. Wiley; 2022; 10.1002/jbt.23146
• Effects of ginger extract and its major component 6‐gingerol on anti‐tumor property through mitochondrial biogenesis in CD8+T cells Cite
  Deng X, Chen D, Sun X, Dong J, Huang J. Effects of ginger extract and its major component 6‐gingerol on anti‐tumor property through mitochondrial biogenesis in CD8+T cells. Journal of Food Science. Wiley; 2022; 10.1111/1750-3841.16228
• [6]-Gingerol: A Narrative Review of Its Beneficial Effect on Human Health Cite
  Promdam N, Panichayupakaranant P. [6]-Gingerol: A Narrative Review of Its Beneficial Effect on Human Health. Food Chemistry Advances. Elsevier BV; 2022;:100043 10.1016/j.focha.2022.100043
• Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties Cite
  Ozkur M, Benlier N, Takan I, Vasileiou C, Georgakilas AG, Pavlopoulou A, et al. Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Oxidative Medicine and Cellular Longevity. Hindawi Limited; 2022; 2022:1-16 10.1155/2022/4748447
• Gingerol/letrozole-loaded mesoporous silica nanoparticles for breast cancer therapy: In-silico and in-vitro studies Cite
  Akbarzadeh I, Poor AS, Khodarahmi M, Abdihaji M, Moammeri A, Jafari S, et al. Gingerol/letrozole-loaded mesoporous silica nanoparticles for breast cancer therapy: In-silico and in-vitro studies. Microporous and Mesoporous Materials. Elsevier BV; 2022;:111919 10.1016/j.micromeso.2022.111919
• Complementary and alternative medicine remedies in the treatment of oncological patients – possible adverse effects and interactions with drugs: a literature review Cite
  . Complementary and alternative medicine remedies in the treatment of oncological patients – possible adverse effects and interactions with drugs: a literature review. Medical Sciences. Lithuanian Research Center of Health Sciences; 2022; 10 10.53453/ms.2022.03.22
• Herb–Drug Interaction in Inflammatory Diseases: Review of Phytomedicine and Herbal Supplements Cite
  Annemarie A, Renner B. Herb–Drug Interaction in Inflammatory Diseases: Review of Phytomedicine and Herbal Supplements. Journal of Clinical Medicine. MDPI AG; 2022; 11:1567 10.3390/jcm11061567
• Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells Cite
  Yu T, Tang J, Shiau J, Hou M, Yen C, Ou-Yang F, et al. Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells. Antioxidants. MDPI AG; 2022; 11:587 10.3390/antiox11030587
• Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases Cite
  Alam M, Ahmed S, Elasbali AM, Adnan M, Alam S, Hassan MI, et al. Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases. Frontiers in Oncology. Frontiers Media SA; 2022; 12 10.3389/fonc.2022.860508
• An investigation of 6-Shogaol effects on MCF7 cell lines through a systems biology approach Cite
  Amjad E, Sokouti B, Asnaashari S. An investigation of 6-Shogaol effects on MCF7 cell lines through a systems biology approach. Egyptian Journal of Medical Human Genetics. Springer Science and Business Media LLC; 2022; 23 10.1186/s43042-022-00276-y
• Zerumbone‐induced reactive oxygen species‐mediated oxidative stress re‐sensitizes breast cancer cells to paclitaxel Cite
  Li J, Wang L, Sun Y, Wang Z, Qian Y, Duraisamy V, et al. Zerumbone‐induced reactive oxygen species‐mediated oxidative stress re‐sensitizes breast cancer cells to paclitaxel. Biotechnology and Applied Biochemistry. Wiley; 2022; 10.1002/bab.2326
• Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement Cite
  Sharma M, Grewal K, Jandrotia R, Batish DR, Singh HP, Kohli RK. Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 146:112514 10.1016/j.biopha.2021.112514
• Cytotoxicity, Phytochemical Screening and Genetic analysis of Ginger (Zingiber officinale Rosc.) Callus and Rhizome Cite
  Ali AM, El-Nour ME, Yagi SM, Qahtan AA, Alatar AA, Abdel-Salam EM, et al. Cytotoxicity, Phytochemical Screening and Genetic analysis of Ginger (Zingiber officinale Rosc.) Callus and Rhizome. South African Journal of Botany. Elsevier BV; 2021; 10.1016/j.sajb.2021.11.011
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Diarylheptanoid analogues from the rhizomes of Zingiber officinale and their anti-tumour activity Cite
  Li T, Pan D, Pang Q, Zhou M, Yao X, Yao X, et al. Diarylheptanoid analogues from the rhizomes of Zingiber officinale and their anti-tumour activity. RSC Advances. Royal Society of Chemistry (RSC); 2021; 11:29376-29384 10.1039/d1ra03592d
• Four Matrix Metalloproteinase genes involved in murine breast cancer affected by ginger extract Cite
  Meysami M, Rahaie M, Ebrahimi A, Samiee F. Four Matrix Metalloproteinase genes involved in murine breast cancer affected by ginger extract. Gene Reports. Elsevier BV; 2021; 25:101332 10.1016/j.genrep.2021.101332
• Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol Cite
  Ahmed SHH, Gonda T, Hunyadi A. Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol. RSC Advances. Royal Society of Chemistry (RSC); 2021; 11:26687-26699 10.1039/d1ra04227k
• Abstract 313: Synergistic interaction between gingerol, shogaol and paradol with platinum-based chemotherapeutic drugs against naïve and resistant breast cancer cells Cite
  Bawadood AS, Al-Abbasi FA, El-Halawany AM, Al-Abd AM. Abstract 313: Synergistic interaction between gingerol, shogaol and paradol with platinum-based chemotherapeutic drugs against naïve and resistant breast cancer cells. Cancer Chemistry. American Association for Cancer Research; 2021; 10.1158/1538-7445.am2021-313
• [10]-Gingerol-Loaded Nanoemulsion and its Biological Effects on Triple-Negative Breast Cancer Cells Cite
  Zanesco-Fontes I, Silva ACL, da Silva PB, Duarte JL, Di Filippo LD, Chorilli M, et al. [10]-Gingerol-Loaded Nanoemulsion and its Biological Effects on Triple-Negative Breast Cancer Cells. AAPS PharmSciTech. Springer Science and Business Media LLC; 2021; 22 10.1208/s12249-021-02006-w
• Isobaric tags for relative and absolute quantitation‑based proteomics analysis of the effect of ginger oil on bisphenol A‑induced breast cancer cell proliferation Cite
  Lei D, Hong T, Li L, Chen L, Luo X, Wu Q, et al. Isobaric tags for relative and absolute quantitation‑based proteomics analysis of the effect of ginger oil on bisphenol A‑induced breast cancer cell proliferation. Oncology Letters. Spandidos Publications; 2020; 21 10.3892/ol.2020.12362
• Efficacy based ginger fingerprinting reveals potential antiproliferative analytes for triple negative breast cancer Cite
  Zhao L, Rupji M, Choudhary I, Osan R, Kapoor S, Zhang H, et al. Efficacy based ginger fingerprinting reveals potential antiproliferative analytes for triple negative breast cancer. Scientific Reports. Springer Science and Business Media LLC; 2020; 10 10.1038/s41598-020-75707-0
• Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials Cite
  Morvaridzadeh M, Fazelian S, Agah S, Khazdouz M, Rahimlou M, Agh F, et al. Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Cytokine. Elsevier BV; 2020; 135:155224 10.1016/j.cyto.2020.155224
• [10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models Cite
  Baptista Moreno Martin AC, Tomasin R, Luna-Dulcey L, Graminha AE, Araújo Naves M, Teles RHG, et al. [10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models. Cellular Oncology. Springer Science and Business Media LLC; 2020; 43:915-929 10.1007/s13402-020-00539-z
• 6-Shogaol suppresses the growth of breast cancer cells by inducing apoptosis and suppressing autophagy via targeting notch signaling pathway Cite
  Bawadood AS, Al-Abbasi FA, Anwar F, El-Halawany AM, Al-Abd AM. 6-Shogaol suppresses the growth of breast cancer cells by inducing apoptosis and suppressing autophagy via targeting notch signaling pathway. Biomedicine & Pharmacotherapy. Elsevier BV; 2020; 128:110302 10.1016/j.biopha.2020.110302
• Ginger and its active compounds in cancer therapy: From folk uses to nano-therapeutic applications Cite
  Mahomoodally M, Aumeeruddy M, Rengasamy KR, Roshan S, Hammad S, Pandohee J, et al. Ginger and its active compounds in cancer therapy: From folk uses to nano-therapeutic applications. Seminars in Cancer Biology. Elsevier BV; 2019; 10.1016/j.semcancer.2019.08.009
• The effect of ginger ( Zingiber officinale ) on chemotherapy‐induced nausea and vomiting in breast cancer patients: A systematic literature review of randomized controlled trials Cite
  Saneei Totmaj A, Emamat H, Jarrahi F, Zarrati M. The effect of ginger ( Zingiber officinale ) on chemotherapy‐induced nausea and vomiting in breast cancer patients: A systematic literature review of randomized controlled trials. Phytotherapy Research. Wiley; 2019; 33:1957-1965 10.1002/ptr.6377
• Fabrication of 6-gingerol, doxorubicin and alginate hydroxyapatite into a bio-compatible formulation: enhanced anti-proliferative effect on breast and liver cancer cells Cite
  Manatunga DC, de Silva RM, de Silva KMN, Wijeratne DT, Malavige GN, Williams G. Fabrication of 6-gingerol, doxorubicin and alginate hydroxyapatite into a bio-compatible formulation: enhanced anti-proliferative effect on breast and liver cancer cells. Chemistry Central Journal. Springer Science and Business Media LLC; 2018; 12 10.1186/s13065-018-0482-6
• [10]-Gingerol Affects Multiple Metastatic Processes and Induces Apoptosis in MDAMB- 231 Breast Tumor Cells Cite
  Fuzer AM, Martin AC, Becceneri AB, da Silva JA, Vieira PC, Cominetti MR. [10]-Gingerol Affects Multiple Metastatic Processes and Induces Apoptosis in MDAMB- 231 Breast Tumor Cells. Anti-Cancer Agents in Medicinal Chemistry. Bentham Science Publishers Ltd.; 2018; 19:645-654 10.2174/1871520618666181029125607
• Antioxidant Activity of Spices and Their Impact on Human Health: A Review Cite
  Yashin A, Yashin Y, Xia X, Nemzer B. Antioxidant Activity of Spices and Their Impact on Human Health: A Review. Antioxidants. MDPI AG; 2017; 6:70 10.3390/antiox6030070
• Anti-cancer potential of a mix of natural extracts of turmeric, ginger and garlic: A cell-based study Cite
  Vemuri SK, Banala RR, Subbaiah G, Srivastava SK, Reddy AG, Malarvili T. Anti-cancer potential of a mix of natural extracts of turmeric, ginger and garlic: A cell-based study. Egyptian Journal of Basic and Applied Sciences. Informa UK Limited; 2017; 4:332-344 10.1016/j.ejbas.2017.07.005
• Zerumbone modulates CD1d expression and lipid antigen presentation pathway in breast cancer cells Cite
  Shyanti RK, Sehrawat A, Singh SV, Mishra J, Singh RP. Zerumbone modulates CD1d expression and lipid antigen presentation pathway in breast cancer cells. Toxicology in Vitro. Elsevier BV; 2017; 44:74-84 10.1016/j.tiv.2017.06.016
• Abstract B40: [10]-gingerol as a pro-apoptotic molecule in triple negative breast cancer Cite
  Martin ACBM, Tomasin R, Becceneri AB, Fuzer A, Vieira PC, Cominetti MR. Abstract B40: [10]-gingerol as a pro-apoptotic molecule in triple negative breast cancer. Exploiting Repair Defects in the Tumor Microenvironment. American Association for Cancer Research; 2017; 10.1158/1557-3125.dnarepair16-b40
• [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells Cite
  Bernard MM, McConnery JR, Hoskin DW. [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells. Experimental and Molecular Pathology. Elsevier BV; 2017; 102:370-376 10.1016/j.yexmp.2017.03.006
• Ginger extract adjuvant to doxorubicin in mammary carcinoma: study of some molecular mechanisms Cite
  El-Ashmawy NE, Khedr NF, El-Bahrawy HA, Abo Mansour HE. Ginger extract adjuvant to doxorubicin in mammary carcinoma: study of some molecular mechanisms. European Journal of Nutrition. Springer Science and Business Media LLC; 2017; 57:981-989 10.1007/s00394-017-1382-6
• Antioxidant activity of ginger extract as a daily supplement in cancer patients receiving adjuvant chemotherapy: a pilot study Cite
  Danwilai K, Konmun J, Sripanidkulchai B, Subongkot S. Antioxidant activity of ginger extract as a daily supplement in cancer patients receiving adjuvant chemotherapy: a pilot study. Cancer Management and Research. Informa UK Limited; 2017; Volume 9:11-18 10.2147/cmar.s124016
• [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture Cite
  Fuzer AM, Lee S, Mott JD, Cominetti MR. [10]-Gingerol Reverts Malignant Phenotype of Breast Cancer Cells in 3D Culture. Journal of Cellular Biochemistry. Wiley; 2017; 118:2693-2699 10.1002/jcb.25906
• The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis Cite
  Mazidi M, Gao H, Rezaie P, Ferns GA. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis. Food & Nutrition Research. SNF Swedish Nutrition Foundation; 2016; 60:32613 10.3402/fnr.v60.32613
• Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study Cite
  Thamlikitkul L, Srimuninnimit V, Akewanlop C, Ithimakin S, Techawathanawanna S, Korphaisarn K, et al. Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study. Supportive Care in Cancer. Springer Science and Business Media LLC; 2016; 25:459-464 10.1007/s00520-016-3423-8
• Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone Cite
  Jeon M, Han J, Nam SJ, Lee JE, Kim S. Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. Chemico-Biological Interactions. Elsevier BV; 2016; 258:126-133 10.1016/j.cbi.2016.08.021
• The Effect of Ginger on Breast Milk Volume in the Early Postpartum Period: A Randomized, Double-Blind Controlled Trial Cite
  Paritakul P, Ruangrongmorakot K, Laosooksathit W, Suksamarnwong M, Puapornpong P. The Effect of Ginger on Breast Milk Volume in the Early Postpartum Period: A Randomized, Double-Blind Controlled Trial. Breastfeeding Medicine. Mary Ann Liebert Inc; 2016; 11:361-365 10.1089/bfm.2016.0073
• Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis Cite
  Funk JL, Frye JB, Oyarzo JN, Chen J, Zhang H, Timmermann BN. Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis. PharmaNutrition. Elsevier BV; 2016; 4:123-131 10.1016/j.phanu.2016.02.004
• The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting Cite
  Salihah N, Mazlan N, Lua PL. The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting. Focus on Alternative and Complementary Therapies. Wiley; 2016; 21:8-16 10.1111/fct.12236
• Ginger augmented chemotherapy: A novel multitarget nontoxic approach for cancer management Cite
  Saxena R, Rida PCG, Kucuk O, Aneja R. Ginger augmented chemotherapy: A novel multitarget nontoxic approach for cancer management. Molecular Nutrition & Food Research. Wiley; 2016; 60:1364-1373 10.1002/mnfr.201500955
• Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway Cite
  Kim S, Lee J, Jeon M, Lee JE, Nam SJ. Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway. Oncotarget. Impact Journals, LLC; 2015; 7:1544-1558 10.18632/oncotarget.6441
• Recent perspectives on the medicinal potential of ginger Cite
  Rupasinghe V, Gunathilake K. Recent perspectives on the medicinal potential of ginger. Botanics: Targets and Therapy. Informa UK Limited; 2015;:55 10.2147/btat.s68099
• 10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity Cite
  JOO J, HONG S, CHO Y, SEO D. 10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity. Oncology Reports. Spandidos Publications; 2015; 35:779-784 10.3892/or.2015.4405
• 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death Cite
  Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0137614 10.1371/journal.pone.0137614
• Gingerols and shogaols: Important nutraceutical principles from ginger Cite
  Semwal RB, Semwal DK, Combrinck S, Viljoen AM. Gingerols and shogaols: Important nutraceutical principles from ginger. Phytochemistry. Elsevier BV; 2015; 117:554-568 10.1016/j.phytochem.2015.07.012
• Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene Cite
  Wu C, Hong B, Ho C, Yen G. Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2015; 63:2432-2441 10.1021/acs.jafc.5b00002
• Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells Cite
  KIM S, KIL WH, LEE J, OH S, HAN J, JEON M, et al. Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells. Oncology Reports. Spandidos Publications; 2014; 32:2666-2672 10.3892/or.2014.3514
• 6-Shogaol, a Major Compound in Ginger, Induces Aryl Hydrocarbon Receptor-Mediated Transcriptional Activity and Gene Expression Cite
  Yoshida K, Satsu H, Mikubo A, Ogiwara H, Yakabe T, Inakuma T, et al. 6-Shogaol, a Major Compound in Ginger, Induces Aryl Hydrocarbon Receptor-Mediated Transcriptional Activity and Gene Expression. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2014; 62:5492-5499 10.1021/jf405146j
• Terpenoids from Zingiber officinale (Ginger) Induce Apoptosis in Endometrial Cancer Cells through the Activation of p53 Cite
  Liu Y, Whelan RJ, Pattnaik BR, Ludwig K, Subudhi E, Rowland H, et al. Terpenoids from Zingiber officinale (Ginger) Induce Apoptosis in Endometrial Cancer Cells through the Activation of p53. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e53178 10.1371/journal.pone.0053178
• Synergistic Extraction and Antioxidant Activities of Ginger Polyphenols by Ultrasound Wave and Microwave Cite
  Tang SR, Song H, Chen YJ, Zhu CH. Synergistic Extraction and Antioxidant Activities of Ginger Polyphenols by Ultrasound Wave and Microwave. Advanced Materials Research. Trans Tech Publications, Ltd.; 2012; 550-553:580-585 10.4028/www.scientific.net/amr.550-553.580
• Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells Cite
  Zu Y, Yu H, Liang L, Fu Y, Efferth T, Liu X, et al. Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells. Molecules. MDPI AG; 2010; 15:3200-3210 10.3390/molecules15053200
• 4-Shogaol, an Active Constituent of Dietary Ginger, Inhibits Metastasis of MDA-MB-231 Human Breast Adenocarcinoma Cells by Decreasing the Repression of NF-κB/Snail on RKIP Cite
  Hsu Y, Chen C, Lin I, Tsai E, Kuo P, Hou M. 4-Shogaol, an Active Constituent of Dietary Ginger, Inhibits Metastasis of MDA-MB-231 Human Breast Adenocarcinoma Cells by Decreasing the Repression of NF-κB/Snail on RKIP. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2011; 60:852-861 10.1021/jf2052515
• Ginger (Zingiber officinale Rosc.), a Dietary Supplement, Protects Mice Against Radiation- Induced Lethality: Mechanism of Action Cite
  Jagetia G, Baliga M, Venkatesh P. Ginger (Zingiber officinale Rosc.), a Dietary Supplement, Protects Mice Against Radiation- Induced Lethality: Mechanism of Action. Cancer Biotherapy and Radiopharmaceuticals. Mary Ann Liebert Inc; 2004; 19:422-435 10.1089/cbr.2004.19.422
• [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells Cite
  LEE H, SEO E, KANG N, KIM W. [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells. The Journal of Nutritional Biochemistry. Elsevier BV; 2008; 19:313-319 10.1016/j.jnutbio.2007.05.008