Tag: calorieRestriction

Articles

• Fasting during chemotherapy

News

02/15/21

Time-restricted eating inhibits mammary tumor growth in obese mice

07/11/20

Fasting near chemotherapy linked to better treatment response

03/19/17

Eating after 10 pm linked to increased breast cancer risk

02/16/15

Starvation enhances gene expression leading to programmed cell death

05/27/13

Calorie restriction heightens effects of radiotherapy in TN tumors

03/04/13

Fasting is more effective than calorie cut in model of chemotherapy

05/22/12

Losing weight through diet and exercise can improve hormonal profile

Studies

• Cyclic fasting-mimicking diet in cancer treatment: Preclinical and clinical evidence Cite
  Vernieri C, Ligorio F, Tripathy D, Longo VD. Cyclic fasting-mimicking diet in cancer treatment: Preclinical and clinical evidence. Cell Metabolism. Elsevier BV; 2024; 10.1016/j.cmet.2024.06.014
• Dietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review Cite
  Golonko A, Pienkowski T, Swislocka R, Orzechowska S, Marszalek K, Szczerbinski L, et al. Dietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review. Cell Death & Disease. Springer Science and Business Media LLC; 2024; 15 10.1038/s41419-024-06641-6
• Abstract 707: Calorie restriction to augment radiation response in models of Black women with breast cancer Cite
  Francois NB, Shastri AA, Harding S, DeAngelis T, Adekeye A, Simone N. Abstract 707: Calorie restriction to augment radiation response in models of Black women with breast cancer. Cancer Research. American Association for Cancer Research (AACR); 2024; 84:707-707 10.1158/1538-7445.am2024-707
• Nutrition and dietary restrictions in cancer prevention Cite
  Mishra A, Giuliani G, Longo VD. Nutrition and dietary restrictions in cancer prevention. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. Elsevier BV; 2024; 1879:189063 10.1016/j.bbcan.2023.189063
• Combination of Thymoquinone and Intermittent Fasting as a Treatment for Breast Cancer Implanted in Mice Cite
  Haif SK, Al Kury LT, Talib WH. Combination of Thymoquinone and Intermittent Fasting as a Treatment for Breast Cancer Implanted in Mice. Plants. MDPI AG; 2023; 13:35 10.3390/plants13010035
• Dietary approaches for exploiting metabolic vulnerabilities in cancer Cite
  Menyhárt O, Győrffy B. Dietary approaches for exploiting metabolic vulnerabilities in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. Elsevier BV; 2023;:189062 10.1016/j.bbcan.2023.189062
• LBA94 Effects of short-term fasting on quality of life as an add-on option during chemotherapy Cite
  Koppold D, Kessler C, Wischnewsky M, Alvarado-Rupflin I, Kempter C, Paul M, et al. LBA94 Effects of short-term fasting on quality of life as an add-on option during chemotherapy. Annals of Oncology. Elsevier BV; 2023; 34:S1335 10.1016/j.annonc.2023.10.097
• Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy Cite
  Klement RJ, Figueroa J, Weigel M, Champ CE, Ok S, Sweeney RA. Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy. Holistic Integrative Oncology. Springer Science and Business Media LLC; 2023; 2 10.1007/s44178-023-00058-5
• Fasting mimicking diet in mice delays cancer growth and reduces immunotherapy-associated cardiovascular and systemic side effects Cite
  Cortellino S, Quagliariello V, Delfanti G, Blaževitš O, Chiodoni C, Maurea N, et al. Fasting mimicking diet in mice delays cancer growth and reduces immunotherapy-associated cardiovascular and systemic side effects. Nature Communications. Springer Science and Business Media LLC; 2023; 14 10.1038/s41467-023-41066-3
• Adding fasting‐mimicking diet to first‐line carboplatin‐based chemotherapy is associated with better overall survival in advanced triple‐negative breast cancer patients: A subanalysis of the NCT03340935 trial Cite
  Ligorio F, Lobefaro R, Fucà G, Provenzano L, Zanenga L, Nasca V, et al. Adding fasting‐mimicking diet to first‐line carboplatin‐based chemotherapy is associated with better overall survival in advanced triple‐negative breast cancer patients: A subanalysis of the NCT03340935 trial. International Journal of Cancer. Wiley; 2023; 10.1002/ijc.34701
• Short-term fasting and fasting mimicking diets combined with chemotherapy: a narrative review Cite
  Kikomeko J, Schutte T, van Velzen MJ, Seefat R, van Laarhoven HW. Short-term fasting and fasting mimicking diets combined with chemotherapy: a narrative review. Therapeutic Advances in Medical Oncology. SAGE Publications; 2023; 15:175883592311614 10.1177/17588359231161418
• Caloric restriction and fasting-mimicking diets in the treatment of cancer patients Cite
  Arends J. Caloric restriction and fasting-mimicking diets in the treatment of cancer patients. Current Opinion in Clinical Nutrition & Metabolic Care. Ovid Technologies (Wolters Kluwer Health); 2023; 10.1097/mco.0000000000000959
• Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming Cite
  Pateras IS, Williams C, Gianniou DD, Margetis AT, Avgeris M, Rousakis P, et al. Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming. Journal of Translational Medicine. Springer Science and Business Media LLC; 2023; 21 10.1186/s12967-023-03935-9
• Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells Cite
  Liu X, Peng S, Tang G, Xu G, Xie Y, Shen D, et al. Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells. eBioMedicine. Elsevier BV; 2023; 90:104496 10.1016/j.ebiom.2023.104496
• Intermittent Fasting in Breast Cancer: A Systematic Review and Critical Update of Available Studies Cite
  Anemoulis M, Vlastos A, Kachtsidis V, Karras SN. Intermittent Fasting in Breast Cancer: A Systematic Review and Critical Update of Available Studies. Nutrients. MDPI AG; 2023; 15:532 10.3390/nu15030532
• Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro Cite
  Khajah MA, Khushaish S, Luqmani YA. Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro. PLOS ONE. Public Library of Science (PLoS); 2022; 17:e0272449 10.1371/journal.pone.0272449
• Pilot study to assess prolonged overnight fasting in breast cancer survivors (longfast) Cite
  O’Donnell E, Shapiro Y, Comander A, Isakoff S, Moy B, Spring L, et al. Pilot study to assess prolonged overnight fasting in breast cancer survivors (longfast). Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2022; 10.1007/s10549-022-06594-4
• Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity Cite
  de Gruil N, Pijl H, van der Burg SH, Kroep JR. Short-Term Fasting Synergizes with Solid Cancer Therapy by Boosting Antitumor Immunity. Cancers. MDPI AG; 2022; 14:1390 10.3390/cancers14061390
• Randomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer Cite
  Harvie M, Pegington M, Howell SJ, Bundred N, Foden P, Adams J, et al. Randomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2021; 10.1038/s41416-021-01650-0
• Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape Cite
  Salvadori G, Zanardi F, Iannelli F, Lobefaro R, Vernieri C, Longo VD. Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape. Cell Metabolism. Elsevier BV; 2021; 33:2247-2259.e6 10.1016/j.cmet.2021.10.008
• Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity Cite
  Di Conza G, Tsai C, Gallart-Ayala H, Yu Y, Franco F, Zaffalon L, et al. Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity. Nature Immunology. Springer Science and Business Media LLC; 2021; 22:1403-1415 10.1038/s41590-021-01047-4
• Do Fasting, CR and FMD Improve the Chemotherapy Response, Reduce Off-Target Toxicities and Enhance Antitumour Immunity? Illusion or Clinical Reality? Cite
  Gacche RN. Do Fasting, CR and FMD Improve the Chemotherapy Response, Reduce Off-Target Toxicities and Enhance Antitumour Immunity? Illusion or Clinical Reality?. Dietary Research and Cancer. Springer Singapore; 2021;:171-188 10.1007/978-981-16-6050-4_16
• Low glycaemic diets alter lipid metabolism to influence tumour growth Cite
  Lien EC, Westermark AM, Zhang Y, Yuan C, Li Z, Lau AN, et al. Low glycaemic diets alter lipid metabolism to influence tumour growth. Nature. Springer Science and Business Media LLC; 2021; 10.1038/s41586-021-04049-2
• Time-Restricted Eating: A Novel and Simple Dietary Intervention for Primary and Secondary Prevention of Breast Cancer and Cardiovascular Disease Cite
  Christensen RAG, Kirkham AA. Time-Restricted Eating: A Novel and Simple Dietary Intervention for Primary and Secondary Prevention of Breast Cancer and Cardiovascular Disease. Nutrients. MDPI AG; 2021; 13:3476 10.3390/nu13103476
• Fasting and Exercise in Oncology: Potential Synergism of Combined Interventions Cite
  Wilson RL, Kang D, Christopher CN, Crane TE, Dieli-Conwright CM. Fasting and Exercise in Oncology: Potential Synergism of Combined Interventions. Nutrients. MDPI AG; 2021; 13:3421 10.3390/nu13103421
• Intermittent fasting in the prevention and treatment of cancer Cite
  Clifton KK, Ma CX, Fontana L, Peterson LL. Intermittent fasting in the prevention and treatment of cancer. CA: A Cancer Journal for Clinicians. Wiley; 2021; 10.3322/caac.21694
• Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models Cite
  Das M, Ellies LG, Kumar D, Sauceda C, Oberg A, Gross E, et al. Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models. Nature Communications. Springer Science and Business Media LLC; 2021; 12 10.1038/s41467-020-20743-7
• Fasting-mimicking diet plus chemotherapy in breast cancer treatment Cite
  Vernieri C, Ligorio F, Zattarin E, Rivoltini L, de Braud F. Fasting-mimicking diet plus chemotherapy in breast cancer treatment. Nature Communications. Springer Science and Business Media LLC; 2020; 11 10.1038/s41467-020-18194-1
• Fasting-mimicking diet and hormone therapy induce breast cancer regression Cite
  Caffa I, Spagnolo V, Vernieri C, Valdemarin F, Becherini P, Wei M, et al. Fasting-mimicking diet and hormone therapy induce breast cancer regression. Nature. Springer Science and Business Media LLC; 2020; 583:620-624 10.1038/s41586-020-2502-7
• Starvation stress attenuates the miRNA-target interaction in suppressing breast cancer cell proliferation Cite
  Lü J, Zhang C, Han J, Xu Z, Li Y, Zhen L, et al. Starvation stress attenuates the miRNA-target interaction in suppressing breast cancer cell proliferation. BMC Cancer. Springer Science and Business Media LLC; 2020; 20 10.1186/s12885-020-07118-3
• Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial Cite
  de Groot S, Lugtenberg RT, Cohen D, Welters MJP, Ehsan I, Vreeswijk MPG, et al. Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial. Nature Communications. Springer Science and Business Media LLC; 2020; 11 10.1038/s41467-020-16138-3
• Fasting to enhance Cancer treatment in models: the next steps Cite
  Zhang J, Deng Y, Khoo BL. Fasting to enhance Cancer treatment in models: the next steps. Journal of Biomedical Science. Springer Science and Business Media LLC; 2020; 27 10.1186/s12929-020-00651-0
• Influence of pre-operative oral carbohydrate loading vs. standard fasting procedure on tumor proliferation and clinical outcome in breast cancer patients — a randomized trial Cite
  Lende TH, Austdal M, Varhaugvik AE, Skaland I, Gudlaugsson E, Kvaløy JT, et al. Influence of pre-operative oral carbohydrate loading vs. standard fasting procedure on tumor proliferation and clinical outcome in breast cancer patients — a randomized trial. Research Square; 2019; 10.21203/rs.2.11085/v3
• Physical Activity Plus Energy Restriction Prevents 4T1.2 Mammary Tumor Progression, MDSC Accumulation, and an Immunosuppressive Tumor Microenvironment Cite
  Turbitt WJ, Xu Y, Sosnoski DM, Collins SD, Meng H, Mastro AM, et al. Physical Activity Plus Energy Restriction Prevents 4T1.2 Mammary Tumor Progression, MDSC Accumulation, and an Immunosuppressive Tumor Microenvironment. Cancer Prevention Research. American Association for Cancer Research (AACR); 2019; 12:493-506 10.1158/1940-6207.capr-17-0233
• Overeating, caloric restriction and breast cancer risk by pathologic subtype: the EPIGEICAM study Cite
  Lope V, Martín M, Castelló A, Ruiz A, Casas AM, Baena-Cañada JM, et al. Overeating, caloric restriction and breast cancer risk by pathologic subtype: the EPIGEICAM study. Scientific Reports. Springer Science and Business Media LLC; 2019; 9 10.1038/s41598-019-39346-4
• The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study Cite
  Bauersfeld SP, Kessler CS, Wischnewsky M, Jaensch A, Steckhan N, Stange R, et al. The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4353-2
• Caloric restriction inhibits mammary tumorigenesis in MMTV-ErbB2 transgenic mice through the suppression of ER and ErbB2 pathways and inhibition of epithelial cell stemness in premalignant mammary tissues Cite
  Ma Z, Parris AB, Howard EW, Shi Y, Yang S, Jiang Y, et al. Caloric restriction inhibits mammary tumorigenesis in MMTV-ErbB2 transgenic mice through the suppression of ER and ErbB2 pathways and inhibition of epithelial cell stemness in premalignant mammary tissues. Carcinogenesis. Oxford University Press (OUP); 2018; 39:1264-1273 10.1093/carcin/bgy096
• Caloric restriction counteracts chemotherapy-induced inflammation and increases response to therapy in a triple negative breast cancer model Cite
  Simone BA, Palagani A, Strickland K, Ko K, Jin L, Lim MK, et al. Caloric restriction counteracts chemotherapy-induced inflammation and increases response to therapy in a triple negative breast cancer model. Cell Cycle. Informa UK Limited; 2018; 17:1536-1544 10.1080/15384101.2018.1471314
• To fast, or not to fast before chemotherapy, that is the question Cite
  Caccialanza R, Cereda E, De Lorenzo F, Farina G, Pedrazzoli P. To fast, or not to fast before chemotherapy, that is the question. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4245-5
• Worse survival after breast cancer in women with anorexia nervosa Cite
  Bens A, Papadopoulos FC, Pukkala E, Ekbom A, Gissler M, Mellemkjær L. Worse survival after breast cancer in women with anorexia nervosa. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 168:495-500 10.1007/s10549-017-4618-5
• Incidence of breast cancer in Chinese women exposed to the 1959–1961 great Chinese famine Cite
  He D, Fang Y, Gunter MJ, Xu D, Zhao Y, Zhou J, et al. Incidence of breast cancer in Chinese women exposed to the 1959–1961 great Chinese famine. BMC Cancer. Springer Science and Business Media LLC; 2017; 17 10.1186/s12885-017-3794-3
• Pleiotropic effects of nutritional ketosis: Conceptual framework for keto-adaptation as a breast cancer therapy Cite
  Hyde PN, Lustberg MB, Miller VJ, LaFountain RA, Volek JS. Pleiotropic effects of nutritional ketosis: Conceptual framework for keto-adaptation as a breast cancer therapy. Cancer Treatment and Research Communications. Elsevier BV; 2017; 12:32-39 10.1016/j.ctarc.2017.06.001
• Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy Cite
  Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, et al. Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy. PLOS Biology. Public Library of Science (PLoS); 2017; 15:e2001951 10.1371/journal.pbio.2001951
• Nighttime eating and breast cancer among Chinese women in Hong Kong Cite
  Li M, Tse LA, Chan W, Kwok C, Leung S, Wu C, et al. Nighttime eating and breast cancer among Chinese women in Hong Kong. Breast Cancer Research. Springer Science and Business Media LLC; 2017; 19 10.1186/s13058-017-0821-x
• Long-term incidence of female-specific cancer after bariatric surgery or usual care in the Swedish Obese Subjects Study Cite
  Anveden Å, Taube M, Peltonen M, Jacobson P, Andersson-Assarsson JC, Sjöholm K, et al. Long-term incidence of female-specific cancer after bariatric surgery or usual care in the Swedish Obese Subjects Study. Gynecologic Oncology. Elsevier BV; 2017; 145:224-229 10.1016/j.ygyno.2017.02.036
• The association between China’s Great famine and risk of breast cancer according to hormone receptor status: a hospital-based study Cite
  Alimujiang A, Mo M, Liu Y, Huang N, Liu G, Xu W, et al. The association between China’s Great famine and risk of breast cancer according to hormone receptor status: a hospital-based study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 160:361-369 10.1007/s10549-016-3994-6
• Abstract 4313: Periodic fasting mimicking diet delays cancer development and progression Cite
  Brandhorst S, Navarrete G, Wei M, Morgan TE, Longo VD. Abstract 4313: Periodic fasting mimicking diet delays cancer development and progression. Prevention Research. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-4313
• Stage-Specific MicroRNAs and Their Role in the Anticancer Effects of Calorie Restriction in a Rat Model of ER-Positive Luminal Breast Cancer Cite
  Devlin KL, Sanford T, Harrison LM, LeBourgeois P, Lashinger LM, Mambo E, et al. Stage-Specific MicroRNAs and Their Role in the Anticancer Effects of Calorie Restriction in a Rat Model of ER-Positive Luminal Breast Cancer. PLOS ONE. Public Library of Science (PLoS); 2016; 11:e0159686 10.1371/journal.pone.0159686
• Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance Cite
  Pietrocola F, Pol J, Vacchelli E, Rao S, Enot D, Baracco E, et al. Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell. Elsevier BV; 2016; 30:147-160 10.1016/j.ccell.2016.05.016
• Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity Cite
  Di Biase S, Lee C, Brandhorst S, Manes B, Buono R, Cheng C, et al. Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. Cancer Cell. Elsevier BV; 2016; 30:136-146 10.1016/j.ccell.2016.06.005
• Caloric restriction coupled with radiation decreases metastatic burden in triple negative breast cancer Cite
  Simone BA, Dan T, Palagani A, Jin L, Han SY, Wright C, et al. Caloric restriction coupled with radiation decreases metastatic burden in triple negative breast cancer. Cell Cycle. Informa UK Limited; 2016; 15:2265-2274 10.1080/15384101.2016.1160982
• Dietary intake variability in the cycle of cytotoxic chemotherapy Cite
  Mardas M, Mądry R, Stelmach-Mardas M. Dietary intake variability in the cycle of cytotoxic chemotherapy. Supportive Care in Cancer. Springer Science and Business Media LLC; 2016; 24:2619-2625 10.1007/s00520-015-3072-3
• Fasting-induced differential stress sensitization in cancer treatment Cite
  Di Biase S, Longo VD. Fasting-induced differential stress sensitization in cancer treatment. Molecular & Cellular Oncology. Informa UK Limited; 2016; 3:e1117701 10.1080/23723556.2015.1117701
• The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study Cite
  de Groot S, Vreeswijk MP, Welters MJ, Gravesteijn G, Boei JJ, Jochems A, et al. The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study. BMC Cancer. Springer Science and Business Media LLC; 2015; 15 10.1186/s12885-015-1663-5
• Abstract P4-07-01: Calorie restriction normalizes global microRNA expression by preventing the loss of dicer expression during mammary tumorigenesis Cite
  Devlin KL, Sanford T, Mambo E, Hursting SD. Abstract P4-07-01: Calorie restriction normalizes global microRNA expression by preventing the loss of dicer expression during mammary tumorigenesis. Poster Session Abstracts. American Association for Cancer Research; 2015; 10.1158/1538-7445.sabcs14-p4-07-01
• Prolonged Nightly Fasting and Breast Cancer Risk: Findings from NHANES (2009–2010) Cite
  Marinac CR, Natarajan L, Sears DD, Gallo LC, Hartman SJ, Arredondo E, et al. Prolonged Nightly Fasting and Breast Cancer Risk: Findings from NHANES (2009–2010). Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2015; 24:783-789 10.1158/1055-9965.epi-14-1292
• Starvation Promotes REV1 SUMOylation and p53-Dependent Sensitization of Melanoma and Breast Cancer Cells Cite
  Shim HS, Wei M, Brandhorst S, Longo VD. Starvation Promotes REV1 SUMOylation and p53-Dependent Sensitization of Melanoma and Breast Cancer Cells. Cancer Research. American Association for Cancer Research (AACR); 2015; 75:1056-1067 10.1158/0008-5472.can-14-2249
• Can short-term fasting protect against doxorubicin-induced cardiotoxicity? Cite
  Dirks-Naylor AJ. Can short-term fasting protect against doxorubicin-induced cardiotoxicity?. World Journal of Biological Chemistry. Baishideng Publishing Group Inc.; 2014; 5:269 10.4331/wjbc.v5.i3.269
• The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster Cite
  Jin L, Lim M, Zhao S, Sano Y, Simone BA, Savage JE, et al. The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2014; 146:41-50 10.1007/s10549-014-2978-7
• Caloric restriction augments radiation efficacy in breast cancer Cite
  Saleh A, Simone B, Palazzo J, Savage JE, Sano Y, Dan T, et al. Caloric restriction augments radiation efficacy in breast cancer. Cell Cycle. Informa UK Limited; 2013; 12:1955-1963 10.4161/cc.25016
• Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression Cite
  Brandhorst S, Wei M, Hwang S, Morgan TE, Longo VD. Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Experimental Gerontology. Elsevier BV; 2013; 48:1120-1128 10.1016/j.exger.2013.02.016
• Caloric Restriction Reverses Obesity-Induced Mammary Gland Inflammation in Mice Cite
  Bhardwaj P, Du B, Zhou XK, Sue E, Harbus MD, Falcone DJ, et al. Caloric Restriction Reverses Obesity-Induced Mammary Gland Inflammation in Mice. Cancer Prevention Research. American Association for Cancer Research (AACR); 2013; 6:282-289 10.1158/1940-6207.capr-12-0467
• Nutrient Restriction and Radiation Therapy for Cancer Treatment: When Less Is More Cite
  Champ CE, Baserga R, Mishra MV, Jin L, Sotgia F, Lisanti MP, et al. Nutrient Restriction and Radiation Therapy for Cancer Treatment: When Less Is More. The Oncologist. Wiley; 2013; 18:97-103 10.1634/theoncologist.2012-0164
• Severe caloric restriction in young women during World War II and subsequent breast cancer risk Cite
  Vin-Raviv N, Barchana M, Linn S, Keinan-Boker L. Severe caloric restriction in young women during World War II and subsequent breast cancer risk. International Journal of Clinical Practice. Wiley; 2012; 66:948-958 10.1111/j.1742-1241.2012.02966.x
• Dose‐dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin‐like growth factor‐1 Cite
  Nogueira LM, Lavigne JA, Chandramouli GVR, Lui H, Barrett JC, Hursting SD. Dose‐dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin‐like growth factor‐1. Cancer Medicine. Wiley; 2012; 1:275-288 10.1002/cam4.23
• Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial Cite
  Campbell KL, Foster-Schubert KE, Alfano CM, Wang C, Wang C, Duggan CR, et al. Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2012; 30:2314-2326 10.1200/jco.2011.37.9792
• Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity Cite
  El-Demerdash E, Ali AA, El-Taher DE, Hamada FM. Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity. Journal of Pharmacy and Pharmacology. Wiley; 2011; 64:344-352 10.1111/j.2042-7158.2011.01413.x
• Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients Cite
  Lee C, Longo VD. Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene. Springer Science and Business Media LLC; 2011; 30:3305-3316 10.1038/onc.2011.91
• Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1 Cite
  Onken B, Driscoll M. Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS ONE. Public Library of Science (PLoS); 2010; 5:e8758 10.1371/journal.pone.0008758
• Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index Cite
  Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, et al. Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index. Cancer Research. American Association for Cancer Research (AACR); 2010; 70:1564-1572 10.1158/0008-5472.can-09-3228
• Fasting and differential chemotherapy protection in patients Cite
  Raffaghello L, Safdie F, Bianchi G, Dorff T, Fontana L, Longo VD. Fasting and differential chemotherapy protection in patients. Cell Cycle. Informa UK Limited; 2010; 9:4474-4476 10.4161/cc.9.22.13954
• Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy Cite
  Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, et al. Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy. Science Translational Medicine. American Association for the Advancement of Science (AAAS); 2012; 4:124ra27-124ra27 10.1126/scitranslmed.3003293
• Effects of Energy Restriction and Wheel Running on Mammary Carcinogenesis and Host Systemic Factors in a Rat Model Cite
  Zhu Z, Jiang W, Zacher JH, Neil ES, McGinley JN, Thompson HJ. Effects of Energy Restriction and Wheel Running on Mammary Carcinogenesis and Host Systemic Factors in a Rat Model. Cancer Prevention Research. American Association for Cancer Research (AACR); 2012; 5:414-422 10.1158/1940-6207.capr-11-0454
• Fasting glucose and treatment outcome in breast and colorectal cancer patients treated with targeted agents: results from a historic cohort Cite
  Barba M, Sperati F, Stranges S, Carlomagno C, Nasti G, Iaffaioli V, et al. Fasting glucose and treatment outcome in breast and colorectal cancer patients treated with targeted agents: results from a historic cohort. Annals of Oncology. Elsevier BV; 2012; 23:1838-1845 10.1093/annonc/mdr540
• Effects of Intermittent and Chronic Calorie Restriction on Mammalian Target of Rapamycin (mTOR) and IGF-I Signaling Pathways in Mammary Fat Pad Tissues and Mammary Tumors Cite
  Dogan S, Johannsen A, Grande J, Cleary M. Effects of Intermittent and Chronic Calorie Restriction on Mammalian Target of Rapamycin (mTOR) and IGF-I Signaling Pathways in Mammary Fat Pad Tissues and Mammary Tumors. Nutrition and Cancer. Informa UK Limited; 2011; 63:389-401 10.1080/01635581.2011.535968
• Combination of Intermittent Calorie Restriction and Eicosapentaenoic Acid for Inhibition of Mammary Tumors Cite
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