Tag: thyme

Foods

• • thyme

Studies

• Carvone: A Bioactive Monoterpene with Diverse Pharmacological Applications Cite
  Anjum R, Raza C. Carvone: A Bioactive Monoterpene with Diverse Pharmacological Applications. Current Pharmacology Reports. Springer Science and Business Media LLC; 2025; 11 10.1007/s40495-025-00402-5
• Evaluating the anticancer effects of carnosic acid against breast cancer: An In Vitro investigation Cite
  Borhan A, Bagherlou A, Ghayour MB. Evaluating the anticancer effects of carnosic acid against breast cancer: An In Vitro investigation. Tissue and Cell. Elsevier BV; 2025; 93:102718 10.1016/j.tice.2024.102718
• Exploring the Therapeutic Potential for Breast Cancer of Phytochemicals and Secondary Metabolites in Marjoram, Thyme, and Persimmon Cite
  Mattingly A, Vickery Z, Ivankovic D, Farrell CL, Hakonarson H, Nguyen K, et al. Exploring the Therapeutic Potential for Breast Cancer of Phytochemicals and Secondary Metabolites in Marjoram, Thyme, and Persimmon. Metabolites. MDPI AG; 2024; 14:652 10.3390/metabo14120652
• Thymol-1,2,3-triazole derivatives: Network Pharmacology, Molecular Simulations and Synthesis Targeting Breast Cancer Cite
  Laamari Y, Bimoussa A, Chagaleti BK, Saravanan V, Alotaibi SH, Alotaibi FM, et al. Thymol-1,2,3-triazole derivatives: Network Pharmacology, Molecular Simulations and Synthesis Targeting Breast Cancer. Journal of Molecular Structure. Elsevier BV; 2024;:140060 10.1016/j.molstruc.2024.140060
• Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines Cite
  Taibi M, Elbouzidi A, Haddou M, Baraich A, Ou-Yahia D, Bellaouchi R, et al. Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines. Life. MDPI AG; 2024; 14:1037 10.3390/life14081037
• Carnosic acid: an effective phenolic diterpenoid for prevention and management of cancers via targeting multiple signaling pathways Cite
  Chen X, Wei C, Zhao J, Zhou D, Wang Y, Zhang S, et al. Carnosic acid: an effective phenolic diterpenoid for prevention and management of cancers via targeting multiple signaling pathways. Pharmacological Research. Elsevier BV; 2024;:107288 10.1016/j.phrs.2024.107288
• Chemopreventive Agents from Nature: A Review of Apigenin, Rosmarinic Acid, and Thymoquinone Cite
  Abutayeh RF, Altah M, Mehdawi A, Al-Ataby I, Ardakani A. Chemopreventive Agents from Nature: A Review of Apigenin, Rosmarinic Acid, and Thymoquinone. Current Issues in Molecular Biology. MDPI AG; 2024; 46:6600-6619 10.3390/cimb46070393
• Thymol as adjuvant in oncology: molecular mechanisms, therapeutic potentials, and prospects for integration in cancer management Cite
  Herrera-Bravo J, Belén LH, Reyes ME, Silva V, Fuentealba S, Paz C, et al. Thymol as adjuvant in oncology: molecular mechanisms, therapeutic potentials, and prospects for integration in cancer management. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2024; 10.1007/s00210-024-03196-3
• Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy Cite
  Khan F, Pandey P, Verma M, Ramniwas S, Lee D, Moon S, et al. Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy. Biomedicine & Pharmacotherapy. Elsevier BV; 2024; 173:116363 10.1016/j.biopha.2024.116363
• Comparative analysis of chemical profiles, antioxidant, antibacterial, and anticancer effects of essential oils of two Thymus species from Montenegro Cite
  Preljević K, Pašić I, Vlaović M, Matić IZ, Krivokapić S, Petrović N, et al. Comparative analysis of chemical profiles, antioxidant, antibacterial, and anticancer effects of essential oils of two Thymus species from Montenegro. Fitoterapia. Elsevier BV; 2024;:105871 10.1016/j.fitote.2024.105871
• Network Pharmacology Combined with Molecular Docking, Molecular Dynamics, and In Vitro Experimental Validation Reveals the Therapeutic Potential of Thymus vulgaris L. Essential Oil (Thyme Oil) against Human Breast Cancer Cite
  Alotaibi NM, Alotaibi MO, Alshammari N, Adnan M, Patel M. Network Pharmacology Combined with Molecular Docking, Molecular Dynamics, and In Vitro Experimental Validation Reveals the Therapeutic Potential of Thymus vulgaris L. Essential Oil (Thyme Oil) against Human Breast Cancer. ACS Omega. American Chemical Society (ACS); 2023; 10.1021/acsomega.3c07782
• New insights into the cytotoxic effects of Thymus vulgaris essential oil on the human triple-negative breast cancer cell line MDA-MB-231 Cite
  Benedetti S, Nasoni MG, Luchetti F, Palma F. New insights into the cytotoxic effects of Thymus vulgaris essential oil on the human triple-negative breast cancer cell line MDA-MB-231. Toxicology in Vitro. Elsevier BV; 2023;:105705 10.1016/j.tiv.2023.105705
• Exploring the Potent Anticancer Activity of Essential Oils and Their Bioactive Compounds: Mechanisms and Prospects for Future Cancer Therapy Cite
  Mohamed Abdoul-Latif F, Ainane A, Houmed Aboubaker I, Mohamed J, Ainane T. Exploring the Potent Anticancer Activity of Essential Oils and Their Bioactive Compounds: Mechanisms and Prospects for Future Cancer Therapy. Pharmaceuticals. MDPI AG; 2023; 16:1086 10.3390/ph16081086
• Assessment of thyme honey oral gel for the prevention of adriamycin and cyclophosphamide chemotherapy-induced oral mucositis in patients with breast cancer Cite
  Jahanbani Mazraeh E, Sadighi S, Manifar S, Bakhshandeh H, Rajabi M. Assessment of thyme honey oral gel for the prevention of adriamycin and cyclophosphamide chemotherapy-induced oral mucositis in patients with breast cancer. Supportive Care in Cancer. Springer Science and Business Media LLC; 2023; 31 10.1007/s00520-023-07943-9
• Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms Cite
  Alsamri H, Al Dhaheri Y, Iratni R. Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms. Antioxidants. MDPI AG; 2023; 12:1349 10.3390/antiox12071349
• Antibacterial potential and cytotoxic activity of iron oxide nanoparticles conjugated with thymol (Fe3O4@Glu-Thymol) on breast cancer cells and investigating the expression of BAX, CASP8, and BCL-2 genes Cite
  Fekri Kohan S, Zamani H, Salehzadeh A. Antibacterial potential and cytotoxic activity of iron oxide nanoparticles conjugated with thymol (Fe3O4@Glu-Thymol) on breast cancer cells and investigating the expression of BAX, CASP8, and BCL-2 genes. BioMetals. Springer Science and Business Media LLC; 2023; 10.1007/s10534-023-00516-7
• Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications Cite
  Ijaz S, Iqbal J, Abbasi BA, Ullah Z, Yaseen T, Kanwal S, et al. Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 162:114687 10.1016/j.biopha.2023.114687
• Anti-Inflammatory and Antimicrobial Properties of Thyme Oil and Its Main Constituents Cite
  Vassiliou E, Awoleye O, Davis A, Mishra S. Anti-Inflammatory and Antimicrobial Properties of Thyme Oil and Its Main Constituents. International Journal of Molecular Sciences. MDPI AG; 2023; 24:6936 10.3390/ijms24086936
• Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells Cite
  Shi X, Zhang W, Bao X, Liu X, Yang M, Yin C. Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells. Frontiers in Endocrinology. Frontiers Media SA; 2023; 14 10.3389/fendo.2023.1136067
• The cytotoxic and apoptotic effects of Thymus vulgaris extracts on human breast cancer cell lines Cite
  Çelikok Y, Şener LT, Bütün B, Albeniz’s I. The cytotoxic and apoptotic effects of Thymus vulgaris extracts on human breast cancer cell lines. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2482650/v1
• The Therapeutic Potential of Ethnomedicinally Important Anatolian Thyme Species: A Phytochemical and Biological Assessment Cite
  Eroglu Ozkan E, Ersoy E, Yesil Canturk Y, Mataraci Kara E, Cinar E, Sahin H, et al. The Therapeutic Potential of Ethnomedicinally Important Anatolian Thyme Species: A Phytochemical and Biological Assessment. Frontiers in Pharmacology. Frontiers Media SA; 2022; 13 10.3389/fphar.2022.923063
• Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells Cite
  Elbe H, Ozturk F, Yigitturk G, Baygar T, Cavusoglu T. Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells. Ultrastructural Pathology. Informa UK Limited; 2022;:1-11 10.1080/01913123.2022.2091068
• A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update Cite
  Machado TQ, da Fonseca ACC, Duarte ABS, Robbs BK, de Sousa DP. A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update. BioMed Research International. Hindawi Limited; 2022; 2022:1-20 10.1155/2022/6317201
• Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α Cite
  Chen Y, Zhang J, Zhang M, Song Y, Zhang Y, Fan S, et al. Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α. Clinical and Translational Medicine. Wiley; 2021; 11 10.1002/ctm2.577
• Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases Cite
  Alam M, Ahmed S, Elasbali AM, Adnan M, Alam S, Hassan MI, et al. Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases. Frontiers in Oncology. Frontiers Media SA; 2022; 12 10.3389/fonc.2022.860508
• Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms Cite
  Slika H, Mansour H, Wehbe N, Nasser SA, Iratni R, Nasrallah G, et al. Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 146:112442 10.1016/j.biopha.2021.112442
• Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement Cite
  Sharma M, Grewal K, Jandrotia R, Batish DR, Singh HP, Kohli RK. Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 146:112514 10.1016/j.biopha.2021.112514
• Zn, Cu, and Fe Concentrations in Dehydrated Herbs (Thyme, Rosemary, Cloves, Oregano, and Basil) and the Correlation with the Microbial Counts of Listeria monocytogenes and Other Foodborne Pathogens Cite
  García-Galdeano JM, Villalón-Mir M, Medina-Martínez J, Vázquez-Foronda LM, Zamora-Bustillos JG, Agil A, et al. Zn, Cu, and Fe Concentrations in Dehydrated Herbs (Thyme, Rosemary, Cloves, Oregano, and Basil) and the Correlation with the Microbial Counts of Listeria monocytogenes and Other Foodborne Pathogens. Foods. MDPI AG; 2020; 9:1658 10.3390/foods9111658
• Evaluating the in vitro Cytotoxicity of Thymus vulgaris Essential Oil on MCF-7 and HeLa Cancer Cell Lines Cite
  Khalaf AN, Abed IJ. Evaluating the in vitro Cytotoxicity of Thymus vulgaris Essential Oil on MCF-7 and HeLa Cancer Cell Lines. Iraqi Journal of Science. University of Baghdad College of Science; 2021;:2862-2871 10.24996/ijs.2021.62.9.3
• Linalool Inhibits MCF-7 Tumor Growth in a Xenograft Model by Apoptosis Induction and Immune Modulation Cite
  Zhao Y, Meng X, Zeng Y, Wang C, Chen J, She Z. Linalool Inhibits MCF-7 Tumor Growth in a Xenograft Model by Apoptosis Induction and Immune Modulation. Natural Product Communications. SAGE Publications; 2021; 16:1934578X2110151 10.1177/1934578x211015125
• A systematic review on ethnopharmacology, phytochemistry and pharmacological aspects of Thymus vulgaris Linn. Cite
  Patil SM, Ramu R, Shirahatti PS, Shivamallu C, Amachawadi RG. A systematic review on ethnopharmacology, phytochemistry and pharmacological aspects of Thymus vulgaris Linn.. Heliyon. Elsevier BV; 2021; 7:e07054 10.1016/j.heliyon.2021.e07054
• Carvacrol Promotes Cisplatin-induced Apoptosis of Triple-negative Breast Cancer Through TRPM7 Channels Cite
  Li J, Ye H, Wang J, Qin J, Chen L. Carvacrol Promotes Cisplatin-induced Apoptosis of Triple-negative Breast Cancer Through TRPM7 Channels. Research Square; 2021; 10.21203/rs.3.rs-291089/v1
• Thyme (Thymus vulgaris [Lamiaceae]) Leaves Inhibit Contraction of the Nonpregnant Mouse Uterus Cite
  Bafor EE, Kalu CH, Omoruyi O, Elvis-Offiah UB, Edrada-Ebel R. Thyme (Thymus vulgaris [Lamiaceae]) Leaves Inhibit Contraction of the Nonpregnant Mouse Uterus. Journal of Medicinal Food. Mary Ann Liebert Inc; 2020; 10.1089/jmf.2020.0076
• Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China Cite
  Feng X, Ho SC, Mo X, Lin F, Zhang N, Luo H, et al. Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2019; 29:493-500 10.1097/cej.0000000000000561
• Antioxidant Activity of Spices and Their Impact on Human Health: A Review Cite
  Yashin A, Yashin Y, Xia X, Nemzer B. Antioxidant Activity of Spices and Their Impact on Human Health: A Review. Antioxidants. MDPI AG; 2017; 6:70 10.3390/antiox6030070
• An in vitro study on antimicrobial and anticancer potentiality of thyme and clove oils Cite
  El-Darier SM, El-Ahwany AMD, Elkenany ET, Abdeldaim AA. An in vitro study on antimicrobial and anticancer potentiality of thyme and clove oils. Rendiconti Lincei. Scienze Fisiche e Naturali. Springer Science and Business Media LLC; 2018; 29:131-139 10.1007/s12210-018-0672-0
• In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products Cite
  Foster B, Vandenhoek S, Hana J, Krantis A, Akhtar M, Bryan M, et al. In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products. Phytomedicine. Elsevier BV; 2003; 10:334-342 10.1078/094471103322004839
• Phenolic Acid Composition, Antiatherogenic and Anticancer Potential of Honeys Derived from Various Regions in Greece Cite
  Spilioti E, Jaakkola M, Tolonen T, Lipponen M, Virtanen V, Chinou I, et al. Phenolic Acid Composition, Antiatherogenic and Anticancer Potential of Honeys Derived from Various Regions in Greece. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e94860 10.1371/journal.pone.0094860
• A comprehensive study on the phenolic profile of widely used culinary herbs and spices: Rosemary, thyme, oregano, cinnamon, cumin and bay Cite
  Vallverdú-Queralt A, Regueiro J, Martínez-Huélamo M, Rinaldi Alvarenga JF, Leal LN, Lamuela-Raventos RM. A comprehensive study on the phenolic profile of widely used culinary herbs and spices: Rosemary, thyme, oregano, cinnamon, cumin and bay. Food Chemistry. Elsevier BV; 2014; 154:299-307 10.1016/j.foodchem.2013.12.106
• Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts Cite
  Roby MHH, Sarhan MA, Selim KA, Khalel KI. Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts. Industrial Crops and Products. Elsevier BV; 2013; 43:827-831 10.1016/j.indcrop.2012.08.029
• Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells Cite
  Zu Y, Yu H, Liang L, Fu Y, Efferth T, Liu X, et al. Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells. Molecules. MDPI AG; 2010; 15:3200-3210 10.3390/molecules15053200