Tag: progesterone
Progesterone: A steriod hormone that stimulates the uterus to prepare for pregnancy by increasing the thickness of the lining (endometrium). Progesterone is produced by the ovaries during ovulation and by the adrenal glands; it is also stored in fat tissue. Progesterone binds to progesterone receptors.
News
- 03/30/11
- Although similar, ER+/PR- BC is more aggressive than ER+/PR+
- 10/02/10
- Soy protein isolate may increase PR expression & tumor aggressiveness
Studies
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Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer
Cite
Diep CH, Mauro LJ, Lange CA. Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer. Steroids. Elsevier BV; 2023; 200:109329 10.1016/j.steroids.2023.109329
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Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization
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Tin ST, Smith-Byrne K, Ferrari P, Rinaldi S, McCullough ML, Teras LR, et al. Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3249588/v1
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Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case–control study and meta-analysis
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Fitzpatrick D, Pirie K, Reeves G, Green J, Beral V. Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case–control study and meta-analysis. PLOS Medicine. Public Library of Science (PLoS); 2023; 20:e1004188 10.1371/journal.pmed.1004188
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The clinical value of progesterone receptor expression in luminal breast cancer: A study of a large cohort with long‐term follow‐up
Cite
Lashen AG, Toss MS, Mongan NP, Green AR, Rakha EA. The clinical value of progesterone receptor expression in luminal breast cancer: A study of a large cohort with long‐term follow‐up. Cancer. Wiley; 2023; 10.1002/cncr.34655
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Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations
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Zamir A, Ben-Zeev T, Hoffman JR. Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations. Nutrients. MDPI AG; 2021; 13:3375 10.3390/nu13103375
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Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors
Cite
Cardona B, Rudel RA. Application of an in Vitro Assay to Identify Chemicals That Increase Estradiol and Progesterone Synthesis and Are Potential Breast Cancer Risk Factors. Environmental Health Perspectives. Environmental Health Perspectives; 2021; 129:077003 10.1289/ehp8608
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Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation
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Shamseddin M, De Martino F, Constantin C, Scabia V, Lancelot A, Laszlo C, et al. Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation. EMBO Molecular Medicine. EMBO; 2021; 10.15252/emmm.202114314
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Spotlight on Ki67 as a prognostic marker in early breast cancer: all that glitters may not be gold
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Maltoni R, Palleschi M, Ravaioli S, Tumedei MM, Altini M, Bravaccini S. Spotlight on Ki67 as a prognostic marker in early breast cancer: all that glitters may not be gold. Diagnostic Pathology. Springer Science and Business Media LLC; 2020; 15 10.1186/s13000-020-01024-9
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Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population
Cite
Recouvreux MS, Diaz Bessone MI, Taruselli A, Todaro L, Lago Huvelle MA, Sampayo RG, et al. Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population. Cells. MDPI AG; 2020; 9:2074 10.3390/cells9092074
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Association of Circulating Progesterone With Breast Cancer Risk Among Postmenopausal Women
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Trabert B, Bauer DC, Buist DSM, Cauley JA, Falk RT, Geczik AM, et al. Association of Circulating Progesterone With Breast Cancer Risk Among Postmenopausal Women. JAMA Network Open. American Medical Association (AMA); 2020; 3:e203645 10.1001/jamanetworkopen.2020.3645
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Effect of Physical Training on the Levels of Sex Hormones and the Expression of Their Receptors in Rats With Induced Mammary Cancer in Secondary Prevention Model – Preliminary Study
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SIEWIERSKA K, MALICKA I, KOBIERZYCKI C, GRZEGRZOLKA J, PIOTROWSKA A, PASLAWSKA U, et al. Effect of Physical Training on the Levels of Sex Hormones and the Expression of Their Receptors in Rats With Induced Mammary Cancer in Secondary Prevention Model – Preliminary Study. In Vivo. Anticancer Research USA Inc.; 2020; 34:495-501 10.21873/invivo.11800
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Folic acid prevents the progesterone-promoted proliferation and migration in breast cancer cell lines
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Wang H, Huo Y, Lee W. Folic acid prevents the progesterone-promoted proliferation and migration in breast cancer cell lines. European Journal of Nutrition. Springer Science and Business Media LLC; 2019; 59:2333-2344 10.1007/s00394-019-02077-3
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Progesterone receptor status modifies the association between body mass index and prognosis in women diagnosed with estrogen receptor positive breast cancer
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Oudanonh T, Nabi H, Ennour‐Idrissi K, Lemieux J, Diorio C. Progesterone receptor status modifies the association between body mass index and prognosis in women diagnosed with estrogen receptor positive breast cancer. International Journal of Cancer. Wiley; 2020; 146:2736-2745 10.1002/ijc.32621
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Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach
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Pollack AZ, Mumford SL, Krall JR, Carmichael AE, Sjaarda LA, Perkins NJ, et al. Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach. Environment International. Elsevier BV; 2018; 120:137-144 10.1016/j.envint.2018.07.028
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The relationship between fat and progesterone, estradiol, and chorionic gonadotropin levels in Quebec cow’s milk
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Gilman AR, Buckett W, Son WY, Lefebvre J, Mahfoudh AM, Dahan MH. The relationship between fat and progesterone, estradiol, and chorionic gonadotropin levels in Quebec cow’s milk. Journal of Assisted Reproduction and Genetics. Springer Science and Business Media LLC; 2017; 34:1567-1569 10.1007/s10815-017-1025-0
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Progesterone receptor modulates ERα action in breast cancer
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Mohammed H, Russell IA, Stark R, Rueda OM, Hickey TE, Tarulli GA, et al. Progesterone receptor modulates ERα action in breast cancer. Nature. Springer Science and Business Media LLC; 2015; 523:313-317 10.1038/nature14583
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Efficacy of endocrine therapy in relation to progesterone receptor and Ki67 expression in advanced breast cancer
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Rocca A, Farolfi A, Maltoni R, Carretta E, Melegari E, Ferrario C, et al. Efficacy of endocrine therapy in relation to progesterone receptor and Ki67 expression in advanced breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2015; 152:57-65 10.1007/s10549-015-3423-2
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Hormone Use in Food Animal Production: Assessing Potential Dietary Exposures and Breast Cancer Risk
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Nachman KE, Smith TJS. Hormone Use in Food Animal Production: Assessing Potential Dietary Exposures and Breast Cancer Risk. Current Environmental Health Reports. Springer Science and Business Media LLC; 2015; 2:1-14 10.1007/s40572-014-0042-8
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The effect of low doses of zearalenone and its metabolites on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
Cite
Gajęcka M, Zielonka Ł, Dąbrowski M, Mróz M, Gajęcki M. The effect of low doses of zearalenone and its metabolites on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs. Toxicon. Elsevier BV; 2013; 76:260-269 10.1016/j.toxicon.2013.08.060
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Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer
Cite
Kim JJ, Kurita T, Bulun SE. Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer. Endocrine Reviews. The Endocrine Society; 2013; 34:130-162 10.1210/er.2012-1043
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Estrogen and progesterone receptor status in breast cancer: Effect of oral contraceptive pills and hormone replacement therapy
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Tewari M, Pradhan S, Singh U, Shukla HS. Estrogen and progesterone receptor status in breast cancer: Effect of oral contraceptive pills and hormone replacement therapy. The Breast. Elsevier BV; 2007; 16:540-545 10.1016/j.breast.2007.05.005
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Progesterone receptor is involved in 2,3,7,8-tetrachlorodibenzo- p -dioxin-stimulated breast cancer cells proliferation
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Chen Y, Hung C, Kay N, Chen C, Kao Y, Yuan S. Progesterone receptor is involved in 2,3,7,8-tetrachlorodibenzo- p -dioxin-stimulated breast cancer cells proliferation. Cancer Letters. Elsevier BV; 2012; 319:223-231 10.1016/j.canlet.2012.01.017
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Apigenin Prevents Development of Medroxyprogesterone Acetate-Accelerated 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Sprague–Dawley Rats
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Mafuvadze B, Benakanakere I, López Pérez FR, Besch-Williford C, Ellersieck MR, Hyder SM. Apigenin Prevents Development of Medroxyprogesterone Acetate-Accelerated 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Sprague–Dawley Rats. Cancer Prevention Research. American Association for Cancer Research (AACR); 2011; 4:1316-1324 10.1158/1940-6207.capr-10-0382
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A Review of an Unfavorable Subset of Breast Cancer: Estrogen Receptor Positive Progesterone Receptor Negative
Cite
Thakkar JP, Mehta DG. A Review of an Unfavorable Subset of Breast Cancer: Estrogen Receptor Positive Progesterone Receptor Negative. The Oncologist. Wiley; 2011; 16:276-285 10.1634/theoncologist.2010-0302
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Enhanced Mammary Progesterone Receptor-A Isoform Activity in the Promotion of Mammary Tumor Progression by Dietary Soy in Rats
Cite
Dave B, Wynne R, Su Y, Korourian S, Chang JC, Simmen RCM. Enhanced Mammary Progesterone Receptor-A Isoform Activity in the Promotion of Mammary Tumor Progression by Dietary Soy in Rats. Nutrition and Cancer. Informa UK Limited; 2010; 62:774-782 10.1080/01635581.2010.494334
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Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats
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Nielsen TS, Khan G, Davis J, Michels KB, Hilakivi-Clarke L. Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats. International Journal of Cancer. Wiley; 2010; 128:12-20 10.1002/ijc.25313
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Progesterone induces adult mammary stem cell expansion
Cite
Joshi PA, Jackson HW, Beristain AG, Di Grappa MA, Mote PA, Clarke CL, et al. Progesterone induces adult mammary stem cell expansion. Nature. Springer Science and Business Media LLC; 2010; 465:803-807 10.1038/nature09091
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Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC)
Cite
Ruder EH, Hartman TJ, Rovine MJ, Dorgan JF. Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC). Cancer Causes & Control. Springer Science and Business Media LLC; 2010; 21:1379-1386 10.1007/s10552-010-9565-y
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Menopausal hormone therapy and breast cancer risk: Impact of different treatments. The European Prospective Investigation into Cancer and Nutrition
Cite
Bakken K, Fournier A, Lund E, Waaseth M, Dumeaux V, Clavel-Chapelon F, et al. Menopausal hormone therapy and breast cancer risk: Impact of different treatments. The European Prospective Investigation into Cancer and Nutrition. International Journal of Cancer. Wiley; 2010; 128:144-156 10.1002/ijc.25314
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New-Onset Breast Tenderness After Initiation of Estrogen Plus Progestin Therapy and Breast Cancer Risk
Cite
Crandall CJ. New-Onset Breast Tenderness After Initiation of Estrogen Plus Progestin Therapy and Breast Cancer Risk. Archives of Internal Medicine. American Medical Association (AMA); 2009; 169:1684 10.1001/archinternmed.2009.303
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The effects ofAnethum graveolensL. on female reproductive system
Cite
Monsefi M, Ghasemi M, Bahaoddini A. The effects ofAnethum graveolensL. on female reproductive system. Phytotherapy Research. Wiley; 2006; 20:865-868 10.1002/ptr.1959
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Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic Mammary Lesions
Cite
Kleinberg DL, Wood TL, Furth PA, Lee AV. Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic Mammary Lesions. Endocrine Reviews. The Endocrine Society; 2008; 30:51-74 10.1210/er.2008-0022