Tag: luteolin

Articles

• Supplements with warnings for breast cancer

News

08/31/20

Luteolin suppresses migration of triple negative breast cancer cells

12/22/16

Luteolin inhibits the metastasis of triple negative breast cancer

09/30/13

Luteolin counteracts some tumor-promoting effects of a high fat diet

05/07/13

Luteolin improves treatment in tamoxifen-resistant BC

08/05/12

Vegetable pigment luteolin suppresses estrogen production

12/05/11

The yellow vegetable pigment luteolin induces BC cell death

Foods

• • artichokes
  • celery
  • hot peppers
  • parsley
  • sage
  • thyme

Studies

• Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies Cite
  Mod Razif MRF, Chan SY, Chew Y, Hassan M, Ahmad Hisham S, Abdul Rahman S, et al. Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies. Sci. MDPI AG; 2024; 6:68 10.3390/sci6040068
• Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment Cite
  Nguyen MH, Nguyen TYN, Le THN, Le TNT, Chau NTN, Le TMH, et al. Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment. Heliyon. Elsevier BV; 2024; 10:e39229 10.1016/j.heliyon.2024.e39229
• Progress, pharmacokinetics and future perspectives of luteolin modulating signaling pathways to exert anticancer effects: A review Cite
  Wang R, Li X, Xu Y, Li Y, Zhang W, Guo R, et al. Progress, pharmacokinetics and future perspectives of luteolin modulating signaling pathways to exert anticancer effects: A review. Medicine. Ovid Technologies (Wolters Kluwer Health); 2024; 103:e39398 10.1097/md.0000000000039398
• Combining luteolin and curcumin synergistically suppresses triple-negative breast cancer by regulating IFN and TGF-β signaling pathways Cite
  Wang X, Zhang L, Si H. Combining luteolin and curcumin synergistically suppresses triple-negative breast cancer by regulating IFN and TGF-β signaling pathways. Biomedicine & Pharmacotherapy. Elsevier BV; 2024; 178:117221 10.1016/j.biopha.2024.117221
• Enhanced Apoptotic Effects in MDA-MB-231 Triple-Negative Breast Cancer Cells Through a Synergistic Action of Luteolin and Paclitaxel Cite
  Tamanna S, Perumal E, Rajanathadurai J. Enhanced Apoptotic Effects in MDA-MB-231 Triple-Negative Breast Cancer Cells Through a Synergistic Action of Luteolin and Paclitaxel. Cureus. Springer Science and Business Media LLC; 2024; 10.7759/cureus.65159
• Phytochemical‐mediated modulation of autophagy and endoplasmic reticulum stress as a cancer therapeutic approach Cite
  Al Azzani M, Nizami ZN, Magramane R, Sekkal MN, Eid AH, Al Dhaheri Y, et al. Phytochemical‐mediated modulation of autophagy and endoplasmic reticulum stress as a cancer therapeutic approach. Phytotherapy Research. Wiley; 2024; 10.1002/ptr.8283
• Computational Exploration of Naturally Occurring Flavonoids as TGF‐β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In‐vitro Cytotoxicity Study Cite
  SHAH U, Patel N, Patel M, Rohit S, Solanki N, Patel A, et al. Computational Exploration of Naturally Occurring Flavonoids as TGF‐β Inhibitors in Breast Cancer: Insights from Docking and Molecular Dynamics Simulations and In‐vitro Cytotoxicity Study. Chemistry & Biodiversity. Wiley; 2024; 10.1002/cbdv.202301903
• Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors Cite
  Ravindra B. Malabadi , Sadiya MR , Kiran P. Kolkar , Simuzar S. Mammadova , Raju K. Chalannavar , Himansu Baijnath , et al. Triple Negative Breast Cancer (TNBC): Signalling pathways-Role of plant-based inhibitors. Open Access Research Journal of Biology and Pharmacy. Open Access Research Journals Publication; 2024; 10:028-071 10.53022/oarjbp.2024.10.2.0013
• Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model Cite
  Mediratta K, El-Sahli S, Marotel M, Awan MZ, Kirkby M, Salkini A, et al. Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model. Frontiers in Immunology. Frontiers Media SA; 2024; 15 10.3389/fimmu.2024.1366197
• Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules Cite
  Almatroodi SA, Almatroudi A, Alharbi HOA, Khan AA, Rahmani AH. Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules. Molecules. MDPI AG; 2024; 29:1093 10.3390/molecules29051093
• Evaluating flavonoids as potential aromatase inhibitors for breast cancer treatment: In vitro studies and in silico predictions Cite
  Seo JI, Yu JS, Zhang Y, Yoo HH. Evaluating flavonoids as potential aromatase inhibitors for breast cancer treatment: In vitro studies and in silico predictions. Chemico-Biological Interactions. Elsevier BV; 2024;:110927 10.1016/j.cbi.2024.110927
• Revisiting luteolin: An updated review on its anticancer potential Cite
  Rauf A, Wilairatana P, Joshi PB, Ahmad Z, Olatunde A, Hafeez N, et al. Revisiting luteolin: An updated review on its anticancer potential. Heliyon. Elsevier BV; 2024;:e26701 10.1016/j.heliyon.2024.e26701
• Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer Cite
  da Silva FC, Brandão DC, Ferreira EA, Siqueira RP, Ferreira HSV, Da Silva Filho AA, et al. Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer. Pharmaceuticals. MDPI AG; 2023; 16:1466 10.3390/ph16101466
• Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling Cite
  Kubatka P, Koklesova L, Mazurakova A, Brockmueller A, Büsselberg D, Kello M, et al. Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling. Cancer and Metastasis Reviews. Springer Science and Business Media LLC; 2023; 10.1007/s10555-023-10134-x
• The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC) Cite
  Farghadani R, Naidu R. The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC). Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 165:115170 10.1016/j.biopha.2023.115170
• Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling Cite
  Wu L, Lin Y, Gao S, Wang Y, Pan H, Wang Z, et al. Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling. Frontiers in Pharmacology. Frontiers Media SA; 2023; 14 10.3389/fphar.2023.1200843
• Therapeutic Potential of Luteolin on Cancer Cite
  Çetinkaya M, Baran Y. Therapeutic Potential of Luteolin on Cancer. Vaccines. MDPI AG; 2023; 11:554 10.3390/vaccines11030554
• Luteolin: a flavonoid with a multifaceted anticancer potential Cite
  Prasher P, Sharma M, Singh SK, Gulati M, Chellappan DK, Zacconi F, et al. Luteolin: a flavonoid with a multifaceted anticancer potential. Cancer Cell International. Springer Science and Business Media LLC; 2022; 22 10.1186/s12935-022-02808-3
• Synergistic effects of natural compounds and conventional chemotherapeutic agents: recent insights for the development of cancer treatment strategies Cite
  Castañeda AM, Meléndez CM, Uribe D, Pedroza-Díaz J. Synergistic effects of natural compounds and conventional chemotherapeutic agents: recent insights for the development of cancer treatment strategies. Heliyon. Elsevier BV; 2022; 8:e09519 10.1016/j.heliyon.2022.e09519
• Effects of Luteolin on Human Breast Cancer Using Gene Expression Array: Inferring Novel Genes Cite
  Wang S, Wu C, Tsai C, Chen T, Tsai K, Hung C, et al. Effects of Luteolin on Human Breast Cancer Using Gene Expression Array: Inferring Novel Genes. Current Issues in Molecular Biology. MDPI AG; 2022; 44:2107-2121 10.3390/cimb44050142
• Polyphenols, Luteolin and Pelargonidin, Modulate Radio- and Chemo-Sensitivity on Breast Cancer Cite
  El-Sheikh MM, Abdel-Naby DH, EL-Hamoly T. Polyphenols, Luteolin and Pelargonidin, Modulate Radio- and Chemo-Sensitivity on Breast Cancer. Egyptian Journal of Radiation Sciences and Applications. Egypts Presidential Specialized Council for Education and Scientific Research; 2022; 0:0-0 10.21608/ejrsa.2022.113425.1127
• Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics Cite
  Meerson A, Khatib S, Mahajna J. Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics. International Journal of Molecular Sciences. MDPI AG; 2021; 22:13044 10.3390/ijms222313044
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Therapeutic role of flavonoids and flavones in cancer prevention: Current trends and future perspectives Cite
  Khan AU, Dagur HS, Khan M, Malik N, Alam M, Mushtaque M. Therapeutic role of flavonoids and flavones in cancer prevention: Current trends and future perspectives. European Journal of Medicinal Chemistry Reports. Elsevier BV; 2021;:100010 10.1016/j.ejmcr.2021.100010
• Luteolin-Loading Her-2 Nanospheres Enhances Targeting and Therapeutic Effects of Breast Cancer Cite
  Xiao C, Wang X, Shen J, Xia Y, Qiu S, Liang X, et al. Luteolin-Loading Her-2 Nanospheres Enhances Targeting and Therapeutic Effects of Breast Cancer. Journal of Biomedical Nanotechnology. American Scientific Publishers; 2021; 17:1545-1553 10.1166/jbn.2021.3137
• Endogenous estrogens—breast cancer and chemoprevention Cite
  Starek-Świechowicz B, Budziszewska B, Starek A. Endogenous estrogens—breast cancer and chemoprevention. Pharmacological Reports. Springer Science and Business Media LLC; 2021; 10.1007/s43440-021-00317-0
• Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy Cite
  Sabo AA, Dudau M, Constantin GL, Pop TC, Geilfus C, Naccarati A, et al. Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy. Frontiers in Pharmacology. Frontiers Media SA; 2021; 12 10.3389/fphar.2021.652074
• Luteolin mitigates tamoxifen-associated fatty liver and cognitive impairment in rats by modulating beta-catenin Cite
  El-Asfar RK, El-Derany MO, Sallam AM, Wahdan SA, El-Demerdash E, Sayed SA, et al. Luteolin mitigates tamoxifen-associated fatty liver and cognitive impairment in rats by modulating beta-catenin. European Journal of Pharmacology. Elsevier BV; 2021; 908:174337 10.1016/j.ejphar.2021.174337
• Luteolin and cancer metastasis suppression: focus on the role of epithelial to mesenchymal transition Cite
  Hussain Y, Cui JH, Khan H, Aschner M, Batiha GE, Jeandet P. Luteolin and cancer metastasis suppression: focus on the role of epithelial to mesenchymal transition. Medical Oncology. Springer Science and Business Media LLC; 2021; 38 10.1007/s12032-021-01508-8
• Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis Cite
  Owumi S, Lewu D, Arunsi U, Oyelere A. Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis. Human & Experimental Toxicology. SAGE Publications; 2021;:096032712110061 10.1177/09603271211006171
• Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis by epigenetic regulation of MMP9 expression via the AKT/mTOR signaling pathway Cite
  Wu H, Lin J, Liu Y, Chen H, Hsu K, Lin S, et al. Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis by epigenetic regulation of MMP9 expression via the AKT/mTOR signaling pathway. Phytomedicine. Elsevier BV; 2020; 81:153437 10.1016/j.phymed.2020.153437
• The effect of hesperidin and luteolin isolated from Eriocephalus africanus on apoptosis, cell cycle and miRNA expression in MCF-7 Cite
  Magura J, Moodley R, Mackraj I. The effect of hesperidin and luteolin isolated from Eriocephalus africanus on apoptosis, cell cycle and miRNA expression in MCF-7. Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2020;:1-10 10.1080/07391102.2020.1833757
• Luteolin, an aryl hydrocarbon receptor ligand, suppresses tumor metastasis in vitro and in vivo Cite
  Feng J, Zheng T, Hou Z, Lv C, Xue A, Han T, et al. Luteolin, an aryl hydrocarbon receptor ligand, suppresses tumor metastasis in vitro and in vivo. Oncology Reports. Spandidos Publications; 2020; 10.3892/or.2020.7781
• MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway Cite
  Wu H, Liu Y, Hsu K, Wang Y, Chan Y, Chen Y, et al. MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway. The American Journal of Chinese Medicine. World Scientific Pub Co Pte Lt; 2020; 48:1221-1241 10.1142/s0192415x20500603
• Luteolin suppresses epithelial-mesenchymal transition and migration of triple-negative breast cancer cells by inhibiting YAP/TAZ activity Cite
  Cao D, Zhu G, Lu Y, Yang A, Chen D, Huang H, et al. Luteolin suppresses epithelial-mesenchymal transition and migration of triple-negative breast cancer cells by inhibiting YAP/TAZ activity. Biomedicine & Pharmacotherapy. Elsevier BV; 2020; 129:110462 10.1016/j.biopha.2020.110462
• Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms Cite
  Bhosale PB, Ha SE, Vetrivel P, Kim HH, Kim J, Park K, et al. Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms. Journal of Biomedical Translational Research. Research Institute of Veterinary Medicine; 2020; 21:50-58 10.12729/jbtr.2020.21.2.050
• Flavonoids in Cancer Metastasis Cite
  Liskova A, Koklesova L, Samec M, Smejkal K, Samuel SM, Varghese E, et al. Flavonoids in Cancer Metastasis. Cancers. MDPI AG; 2020; 12:1498 10.3390/cancers12061498
• Luteolin impairs hypoxia adaptation and progression in human breast and colon cancer cells Cite
  Monti E, Marras E, Prini P, Gariboldi MB. Luteolin impairs hypoxia adaptation and progression in human breast and colon cancer cells. European Journal of Pharmacology. Elsevier BV; 2020; 881:173210 10.1016/j.ejphar.2020.173210
• Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China Cite
  Feng X, Ho SC, Mo X, Lin F, Zhang N, Luo H, et al. Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2019; 29:493-500 10.1097/cej.0000000000000561
• Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives Cite
  Ahmed S, Khan H, Fratantonio D, Hasan MM, Sharifi S, Fathi N, et al. Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives. Phytomedicine. Elsevier BV; 2019; 59:152883 10.1016/j.phymed.2019.152883
• Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase Cite
  Huang L, Jin K, Lan H. Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase. Oncology Letters. Spandidos Publications; 2019; 10.3892/ol.2019.10052
• Cuminum cyminum fruits as source of luteolin- 7-O-glucoside, potent cytotoxic flavonoid against breast cancer cell lines Cite
  Goodarzi S, Tabatabaei MJ, Mohammad Jafari R, Shemirani F, Tavakoli S, Mofasseri M, et al. Cuminum cyminum fruits as source of luteolin- 7-O-glucoside, potent cytotoxic flavonoid against breast cancer cell lines. Natural Product Research. Informa UK Limited; 2018; 34:1602-1606 10.1080/14786419.2018.1519824
• Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro Cite
  Hong J, Fristiohady A, Nguyen CH, Milovanovic D, Huttary N, Krieger S, et al. Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro. Frontiers in Pharmacology. Frontiers Media SA; 2018; 9 10.3389/fphar.2018.00220
• Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction Cite
  Chen K, Hsu W, Ho J, Lin C, Chu C, Kandaswami CC, et al. Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction. Journal of Food and Drug Analysis. The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA); 2018; 26:1180-1191 10.1016/j.jfda.2018.01.012
• Luteolin inhibits ER-α expression through ILK inhibition is regulated by a pathway involving Twist and YB-1 Cite
  Lin Y, Liu L, Ho C, Hung C, Way T. Luteolin inhibits ER-α expression through ILK inhibition is regulated by a pathway involving Twist and YB-1. Journal of Functional Foods. Elsevier BV; 2018; 42:75-84 10.1016/j.jff.2017.12.059
• Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells Cite
  Wilsher NE, Arroo RR, Matsoukas M, Tsatsakis AM, Spandidos DA, Androutsopoulos VP. Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells. Food and Chemical Toxicology. Elsevier BV; 2017; 110:383-394 10.1016/j.fct.2017.10.051
• Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells Cite
  Cook M, Liang Y, Besch-Williford C, Hyder S. Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells. Breast Cancer: Targets and Therapy. Informa UK Limited; 2016; Volume 9:9-19 10.2147/bctt.s124860
• Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression Cite
  Lin D, Kuang G, Wan J, Zhang X, Li H, Gong X, et al. Luteolin suppresses the metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via downregulation of β-catenin expression. Oncology Reports. Spandidos Publications; 2016; 37:895-902 10.3892/or.2016.5311
• Enhanced Anti-Inflammatory Activities by the Combination of Luteolin and Tangeretin Cite
  Funaro A, Wu X, Song M, Zheng J, Guo S, Rakariyatham K, et al. Enhanced Anti-Inflammatory Activities by the Combination of Luteolin and Tangeretin. Journal of Food Science. Wiley; 2016; 81:H1320-H1327 10.1111/1750-3841.13300
• Abstract P1-16-06: Luteolin inhibits progestin-dependent VEGF induction, stem-cell like characteristics, and tumor progression of human breast cancer cells Cite
  Hyder S, Cook M, Besch-Williford C, Liang Y. Abstract P1-16-06: Luteolin inhibits progestin-dependent VEGF induction, stem-cell like characteristics, and tumor progression of human breast cancer cells. Poster Session Abstracts. American Association for Cancer Research; 2016; 10.1158/1538-7445.sabcs15-p1-16-06
• Estrogenic Activity Including Bone Enhancement and Effect on Lipid Profile of Luteolin-7-O-glucoside Isolated from Trifolium alexandrinum L. in Ovariectomized Rats Cite
  Ammar NM, El-Hawary SS, Mohamed DA, El-Halawany AM, El-Anssary AA, El-Kassem LTA, et al. Estrogenic Activity Including Bone Enhancement and Effect on Lipid Profile of Luteolin-7-O-glucoside Isolated from Trifolium alexandrinum L. in Ovariectomized Rats. Phytotherapy Research. Wiley; 2016; 30:768-773 10.1002/ptr.5564
• Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs Cite
  Sun D, Zhang H, Mao L, Mao C, Chen W, Cui M, et al. Luteolin Inhibits Breast Cancer Development and Progression In Vitro and In Vivo by Suppressing Notch Signaling and Regulating MiRNAs. Cellular Physiology and Biochemistry. S. Karger AG; 2015; 37:1693-1711 10.1159/000438535
• Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis Cite
  Cook MT, Liang Y, Goyette S, Mafuvadze B, Besch-Williford C, Hyder S. Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis. Tumor Biology. American Association for Cancer Research; 2015; 10.1158/1538-7445.am2015-4159
• Epigenetic activities of flavonoids in the prevention and treatment of cancer Cite
  Busch C, Burkard M, Leischner C, Lauer UM, Frank J, Venturelli S. Epigenetic activities of flavonoids in the prevention and treatment of cancer. Clinical Epigenetics. Springer Science and Business Media LLC; 2015; 7 10.1186/s13148-015-0095-z
• Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells—A SAR study Cite
  Amrutha K, Nanjan P, Shaji SK, Sunilkumar D, Subhalakshmi K, Rajakrishna L, et al. Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells—A SAR study. Bioorganic & Medicinal Chemistry Letters. Elsevier BV; 2014; 24:4735-4742 10.1016/j.bmcl.2014.07.093
• Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3 Cite
  Yang M, Wang C, Chen N, Ho W, Lu F, Tseng T. Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3. Chemico-Biological Interactions. Elsevier BV; 2014; 213:60-68 10.1016/j.cbi.2014.02.002
• Luteolin Supplementation Modulates Mammary Tumor Growth in C3H Mice Fed Diet with High- and Low-Fat Content Cite
  Song M, Lee E, Yang Y, Sung M. Luteolin Supplementation Modulates Mammary Tumor Growth in C3H Mice Fed Diet with High- and Low-Fat Content. Nutrition and Cancer. Informa UK Limited; 2013; 66:523-530 10.1080/01635581.2013.780629
• Ocimum SanctumL (Holy Basil or Tulsi) and Its Phytochemicals in the Prevention and Treatment of Cancer Cite
  Baliga MS, Jimmy R, Thilakchand KR, Sunitha V, Bhat NR, Saldanha E, et al. Ocimum SanctumL (Holy Basil or Tulsi) and Its Phytochemicals in the Prevention and Treatment of Cancer. Nutrition and Cancer. Informa UK Limited; 2013; 65:26-35 10.1080/01635581.2013.785010
• Endocrine Disrupting Activities of the Flavonoid Nutraceuticals Luteolin and Quercetin Cite
  Nordeen SK, Bona BJ, Jones DN, Lambert JR, Jackson TA. Endocrine Disrupting Activities of the Flavonoid Nutraceuticals Luteolin and Quercetin. Hormones and Cancer. Springer Science and Business Media LLC; 2013; 4:293-300 10.1007/s12672-013-0150-1
• Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression Cite
  Tu S, Ho C, Liu M, Huang C, Chang H, Chang C, et al. Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression. Food Chemistry. Elsevier BV; 2013; 141:1553-1561 10.1016/j.foodchem.2013.04.077
• Synergistic apoptotic effect of celecoxib and luteolin on breast cancer cells Cite
  JEON Y, SUH YJ. Synergistic apoptotic effect of celecoxib and luteolin on breast cancer cells. Oncology Reports. Spandidos Publications; 2012; 29:819-825 10.3892/or.2012.2158
• Luteolin inhibition of V-ATPasea3-d2interaction decreases osteoclast resorptive activity Cite
  Crasto GJ, Kartner N, Yao Y, Li K, Bullock L, Datti A, et al. Luteolin inhibition of V-ATPasea3-d2interaction decreases osteoclast resorptive activity. Journal of Cellular Biochemistry. Wiley; 2013; 114:929-941 10.1002/jcb.24434
• Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts Cite
  Roby MHH, Sarhan MA, Selim KA, Khalel KI. Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts. Industrial Crops and Products. Elsevier BV; 2013; 43:827-831 10.1016/j.indcrop.2012.08.029
• Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer Cite
  Rocha A, Wang L, Penichet M, Martins-Green M. Pomegranate juice and specific components inhibit cell and molecular processes critical for metastasis of breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 136:647-658 10.1007/s10549-012-2264-5
• Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells Cite
  Lee E, Oh S, Sung M. Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells. Food and Chemical Toxicology. Elsevier BV; 2012; 50:4136-4143 10.1016/j.fct.2012.08.025
• Inhibitory Effect of Luteolin on Estrogen Biosynthesis in Human Ovarian Granulosa Cells by Suppression of Aromatase (CYP19) Cite
  Lu D, Yang L, Wang F, Zhang G. Inhibitory Effect of Luteolin on Estrogen Biosynthesis in Human Ovarian Granulosa Cells by Suppression of Aromatase (CYP19). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:8411-8418 10.1021/jf3022817
• Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway Cite
  Lamy S, Akla N, Ouanouki A, Lord-Dufour S, Béliveau R. Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway. Experimental Cell Research. Elsevier BV; 2012; 318:1586-1596 10.1016/j.yexcr.2012.04.004
• Comparative analysis of phenolic profile, antioxidant, anti-inflammatory and cytotoxic activity of two closely-related Plantain species: Plantago altissima L. and Plantago lanceolata L. Cite
  Beara IN, Lesjak MM, Orčić DZ, Simin NĐ, Četojević-Simin DD, Božin BN, et al. Comparative analysis of phenolic profile, antioxidant, anti-inflammatory and cytotoxic activity of two closely-related Plantain species: Plantago altissima L. and Plantago lanceolata L.. LWT - Food Science and Technology. Elsevier BV; 2012; 47:64-70 10.1016/j.lwt.2012.01.001
• Luteolin induces apoptotic cell death through AIF nuclear translocation mediated by activation of ERK and p38 in human breast cancer cell lines Cite
  Kim MJ, Woo JS, Kwon CH, Kim JH, Kim YK, Kim KH. Luteolin induces apoptotic cell death through AIF nuclear translocation mediated by activation of ERK and p38 in human breast cancer cell lines. Cell Biology International. Wiley; 2012; 36:339-344 10.1042/cbi20110394
• Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: Involvement of cell line-specific apoptotic mechanisms Cite
  Rao PS, Satelli A, Moridani M, Jenkins M, Rao US. Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: Involvement of cell line-specific apoptotic mechanisms. International Journal of Cancer. Wiley; 2011; 130:2703-2714 10.1002/ijc.26308
• Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7 Cite
  Li F, Ye L, Lin S, Leung LK. Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7. Molecular and Cellular Endocrinology. Elsevier BV; 2011; 344:51-58 10.1016/j.mce.2011.06.024
• Flavonoids, Proanthocyanidins, and Cancer Risk: A Network of Case-Control Studies From Italy Cite
  Rossi M, Bosetti C, Negri E, Lagiou P, Vecchia CL. Flavonoids, Proanthocyanidins, and Cancer Risk: A Network of Case-Control Studies From Italy. Nutrition and Cancer. Informa UK Limited; 2010; 62:871-877 10.1080/01635581.2010.509534
• Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells Cite
  Du G, Song Z, Lin H, Han X, Zhang S, Yang Y. Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2008; 372:497-502 10.1016/j.bbrc.2008.05.080
• Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids Cite
  Čipák L, Novotný L, Čipáková I, Rauko P. Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids. Nutrition Research. Elsevier BV; 2003; 23:1045-1057 10.1016/s0271-5317(03)00078-2
• Respiratory activity and phenolic compounds in pre-cut celery Cite
  Viña SZ, Chaves AR. Respiratory activity and phenolic compounds in pre-cut celery. Food Chemistry. Elsevier BV; 2007; 100:1654-1660 10.1016/j.foodchem.2005.12.060
• Flavonoids and Breast Cancer Risk in Italy Cite
  Bosetti C. Flavonoids and Breast Cancer Risk in Italy. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2005; 14:805-808 10.1158/1055-9965.epi-04-0838