Tag: hesperetin

Articles

• Foods to eat & avoid during aromatase inhibitor treatment
• Foods to eat and avoid during Adriamycin chemotherapy
• Supplements with warnings for breast cancer

News

03/29/15

Kaempferol reduces ER+/PR+ breast cancer proliferation

07/09/12

Orange flavonoid hesperidin could interfere with cyclophosphamide

Foods

• • grapefruit
  • lemons
  • oranges

Studies

• Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines Cite
  Raimondi MV, Rigogliuso S, Saiano F, Poma P, Labbozzetta M, Barreca M, et al. Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines. Archiv der Pharmazie. Wiley; 2024; 10.1002/ardp.202400530
• Rhein and hesperidin nanoparticles remodel tumor immune microenvironment by reducing CAFs and CCL2 secreted by CAAs for efficient triple-negative breast cancer therapy Cite
  Huang J, Zhang H, Ma L, Ma N, Luo N, Jin W, et al. Rhein and hesperidin nanoparticles remodel tumor immune microenvironment by reducing CAFs and CCL2 secreted by CAAs for efficient triple-negative breast cancer therapy. International Immunopharmacology. Elsevier BV; 2024; 141:113001 10.1016/j.intimp.2024.113001
• Hesperidin PLGA nanoparticles potentiate the efficacy of aPD-1 in treating triple negative breast cancer by regulating CCL2 and ADPN expression in cancer-associated adipocytes Cite
  Luo N, Ma L, Ma N, Wei J, Zhang H, Jin W, et al. Hesperidin PLGA nanoparticles potentiate the efficacy of aPD-1 in treating triple negative breast cancer by regulating CCL2 and ADPN expression in cancer-associated adipocytes. International Immunopharmacology. Elsevier BV; 2024; 140:112759 10.1016/j.intimp.2024.112759
• Investigating the effect of hesperetin on estrogen receptor alpha (ERα) expression, phosphorylation and activity in MCF-7 cells Cite
  Vosooghi R, Motavalizadehkakhky A, Mansouri A, Mehrzad J, Homayouni M. Investigating the effect of hesperetin on estrogen receptor alpha (ERα) expression, phosphorylation and activity in MCF-7 cells. Gene. Elsevier BV; 2024;:148357 10.1016/j.gene.2024.148357
• Evaluating flavonoids as potential aromatase inhibitors for breast cancer treatment: In vitro studies and in silico predictions Cite
  Seo JI, Yu JS, Zhang Y, Yoo HH. Evaluating flavonoids as potential aromatase inhibitors for breast cancer treatment: In vitro studies and in silico predictions. Chemico-Biological Interactions. Elsevier BV; 2024;:110927 10.1016/j.cbi.2024.110927
• Phytochemicals and Their Usefulness in the Maintenance of Health Cite
  Rodríguez-Negrete EV, Morales-González Á, Madrigal-Santillán EO, Sánchez-Reyes K, Álvarez-González I, Madrigal-Bujaidar E, et al. Phytochemicals and Their Usefulness in the Maintenance of Health. Plants. MDPI AG; 2024; 13:523 10.3390/plants13040523
• Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism Cite
  Wu Q, Li J, Hao S, Guo Y, Li Z, Liu Z, et al. Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 168:115766 10.1016/j.biopha.2023.115766
• Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer Cite
  da Silva FC, Brandão DC, Ferreira EA, Siqueira RP, Ferreira HSV, Da Silva Filho AA, et al. Tailoring Potential Natural Compounds for the Treatment of Luminal Breast Cancer. Pharmaceuticals. MDPI AG; 2023; 16:1466 10.3390/ph16101466
• Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer Cite
  Shakiba E, Bazi A, Ghasemi H, Eshaghi‐Gorji R, Mehdipour SA, Nikfar B, et al. Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer. Journal of Cellular and Molecular Medicine. Wiley; 2023; 10.1111/jcmm.17902
• Various concentrations of hesperetin induce different types of programmed cell death in human breast cancerous and normal cell lines in a ROS-dependent manner Cite
  Samandari-Bahraseman MR, Khorsand B, Zareei S, Amanlou M, Rostamabadi H. Various concentrations of hesperetin induce different types of programmed cell death in human breast cancerous and normal cell lines in a ROS-dependent manner. Chemico-Biological Interactions. Elsevier BV; 2023; 382:110642 10.1016/j.cbi.2023.110642
• Investigating the effect of hesperitine on estrogen receptor expression, phosphorylation and activity in MCF-7 cells Cite
  Vosooghi R, Motavalizadehkakhky A, mansouri a, Mehrzad J, Homayouni M. Investigating the effect of hesperitine on estrogen receptor expression, phosphorylation and activity in MCF-7 cells. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3164979/v1
• The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC) Cite
  Farghadani R, Naidu R. The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC). Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 165:115170 10.1016/j.biopha.2023.115170
• Co-Delivery of Hesperetin and Cisplatin via Hyaluronic Acid-Modified Liposome for Targeted Inhibition of Aggression and Metastasis of Triple-Negative Breast Cancer Cite
  Wang X, Song Y, Yu L, Xue X, Pang M, Li Y, et al. Co-Delivery of Hesperetin and Cisplatin via Hyaluronic Acid-Modified Liposome for Targeted Inhibition of Aggression and Metastasis of Triple-Negative Breast Cancer. ACS Applied Materials & Interfaces. American Chemical Society (ACS); 2023; 10.1021/acsami.3c03233
• The effect of hesperetin on estrogen receptor gene expression and its relationship with the downstream pathways of estrogen receptor alpha Cite
  Bideh M, Safari S, Khedri A, Zangooei M. The effect of hesperetin on estrogen receptor gene expression and its relationship with the downstream pathways of estrogen receptor alpha. Molecular Biology Reports. Springer Science and Business Media LLC; 2023; 10.1007/s11033-023-08616-w
• Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties Cite
  Zeeshan Bhatti M, Ismail H, Khan Kayani W. Plant Secondary Metabolites: Therapeutic Potential and Pharmacological Properties. Secondary Metabolites - Trends and Reviews [Working Title]. IntechOpen; 2022; 10.5772/intechopen.103698
• Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62–Keap1–Nrf2 pathway Cite
  Jia Y, Guo H, Cheng X, Zhang Y, Si M, Shi J, et al. Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62–Keap1–Nrf2 pathway. Food & Function. Royal Society of Chemistry (RSC); 2022; 10.1039/d2fo00298a
• The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats Cite
  Semis HS, Kandemir FM, Kaynar O, Dogan T, Arikan SM. The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats. Life Sciences. Elsevier BV; 2021; 287:120104 10.1016/j.lfs.2021.120104
• The Orange Peel: An Outstanding Source of Chemical Resources Cite
  Fontana G. The Orange Peel: An Outstanding Source of Chemical Resources. Citrus - Research, Development and Biotechnology [Working Title]. IntechOpen; 2021; 10.5772/intechopen.96298
• Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats Cite
  Patel P, Shah J. Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats. Life Sciences. Elsevier BV; 2021; 285:119957 10.1016/j.lfs.2021.119957
• Hesperidin and Chlorogenic Acid Synergistically Inhibit the Growth of Breast Cancer Cells via Estrogen Receptor/Mitochondrial Pathway Cite
  Hsu P, Chen W, Juan-Lu C, Hsieh S, Lin S, Mai R, et al. Hesperidin and Chlorogenic Acid Synergistically Inhibit the Growth of Breast Cancer Cells via Estrogen Receptor/Mitochondrial Pathway. Life. MDPI AG; 2021; 11:950 10.3390/life11090950
• Hesperidin and naringenin Cite
  Rehman MFu, Batool AI, Qadir R, Aslam M. Hesperidin and naringenin. A Centum of Valuable Plant Bioactives. Elsevier; 2021;:403-444 10.1016/b978-0-12-822923-1.00027-3
• Identification of key genes of hesperidin in inhibition of breast cancer stem cells by functional network analysis Cite
  Hermawan A, Khumaira A, Ikawati M, Putri H, Jenie RI, Angraini SM, et al. Identification of key genes of hesperidin in inhibition of breast cancer stem cells by functional network analysis. Computational Biology and Chemistry. Elsevier BV; 2020; 90:107427 10.1016/j.compbiolchem.2020.107427
• The effect of hesperidin and luteolin isolated from Eriocephalus africanus on apoptosis, cell cycle and miRNA expression in MCF-7 Cite
  Magura J, Moodley R, Mackraj I. The effect of hesperidin and luteolin isolated from Eriocephalus africanus on apoptosis, cell cycle and miRNA expression in MCF-7. Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2020;:1-10 10.1080/07391102.2020.1833757
• Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms Cite
  Bhosale PB, Ha SE, Vetrivel P, Kim HH, Kim J, Park K, et al. Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms. Journal of Biomedical Translational Research. Research Institute of Veterinary Medicine; 2020; 21:50-58 10.12729/jbtr.2020.21.2.050
• Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer Cite
  Kongtawelert P, Wudtiwai B, Shwe TH, Pothacharoen P, Phitak T. Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer. Molecules. MDPI AG; 2020; 25:252 10.3390/molecules25020252
• Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats Cite
  Li Y, Kandhare AD, Mukherjee AA, Bodhankar SL. Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats. Regulatory Toxicology and Pharmacology. Elsevier BV; 2019; 105:77-85 10.1016/j.yrtph.2019.04.001
• Hesperetin and Naringenin sensitize HER2 positive cancer cells to death by serving as HER2 Tyrosine Kinase inhibitors Cite
  Chandrika BB, Steephan M, Kumar TS, Sabu A, Haridas M. Hesperetin and Naringenin sensitize HER2 positive cancer cells to death by serving as HER2 Tyrosine Kinase inhibitors. Life Sciences. Elsevier BV; 2016; 160:47-56 10.1016/j.lfs.2016.07.007
• Epigenetic activities of flavonoids in the prevention and treatment of cancer Cite
  Busch C, Burkard M, Leischner C, Lauer UM, Frank J, Venturelli S. Epigenetic activities of flavonoids in the prevention and treatment of cancer. Clinical Epigenetics. Springer Science and Business Media LLC; 2015; 7 10.1186/s13148-015-0095-z
• Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases Cite
  Roohbakhsh A, Parhiz H, Soltani F, Rezaee R, Iranshahi M. Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases. Life Sciences. Elsevier BV; 2015; 124:64-74 10.1016/j.lfs.2014.12.030
• The citrus flavonone hesperetin prevents letrozole-induced bone loss in a mouse model of breast cancer Cite
  Li F, Chow S, Cheung W, Chan FL, Chen S, Leung LK. The citrus flavonone hesperetin prevents letrozole-induced bone loss in a mouse model of breast cancer. The Journal of Nutritional Biochemistry. Elsevier BV; 2013; 24:1112-1116 10.1016/j.jnutbio.2012.08.010
• Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population Cite
  Korkaya H, Kim G, Davis A, Malik F, Henry N, Ithimakin S, et al. Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population. Molecular Cell. Elsevier BV; 2012; 47:570-584 10.1016/j.molcel.2012.06.014
• Hesperidin Inhibits Cyclophosphamide-Induced Tumor Growth Delay in Mice Cite
  Hosseinimehr SJ, Jalayer Z, Naghshvar F, Mahmoudzadeh A. Hesperidin Inhibits Cyclophosphamide-Induced Tumor Growth Delay in Mice. Integrative Cancer Therapies. SAGE Publications; 2012; 11:251-256 10.1177/1534735412448959
• The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice Cite
  Ye L, Chan FL, Chen S, Leung LK. The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice. The Journal of Nutritional Biochemistry. Elsevier BV; 2012; 23:1230-1237 10.1016/j.jnutbio.2011.07.003
• Effect of flavonone hesperidin on the apoptosis of human mammary carcinoma cell line MCF-7 Cite
  Natarajan N, Thamaraiselvan R, Lingaiah H, Srinivasan P, Maruthaiveeran Periyasamy B. Effect of flavonone hesperidin on the apoptosis of human mammary carcinoma cell line MCF-7. Biomedicine & Preventive Nutrition. Elsevier BV; 2011; 1:207-215 10.1016/j.bionut.2011.07.001
• Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7 Cite
  Li F, Ye L, Lin S, Leung LK. Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7. Molecular and Cellular Endocrinology. Elsevier BV; 2011; 344:51-58 10.1016/j.mce.2011.06.024
• Influence of orange juice over the genotoxicity induced by alkylating agents: an in vivo analysis Cite
  Franke SIR, Prá D, Erdtmann B, Henriques JAP, da Silva J. Influence of orange juice over the genotoxicity induced by alkylating agents: an in vivo analysis. Mutagenesis. Oxford University Press (OUP); 2005; 20:279-283 10.1093/mutage/gei034