Tag: garlic
Garlic: The bulb of the garlic plant (Allium sativum).
Articles
News
- 09/13/16
- Garlic compound diallyl trisulfide inhibits triple negative breast cancer metastasis
- 08/01/15
- Garlic compound inhibits protein folding in triple negative BC cells
- 12/21/12
- Garlic compound induces programmed cell death in ER+/PR+ cells
- 01/29/11
- Garlic compounds suppress proliferation by interfering with cell cycle
Foods
Studies
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Food-Derived Phytochemicals from Functional Food (Allium sativum) as VEGF-R1 Inhibitors: A Novel Approach for Triple-Negative Breast Cancer Therapy
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Mahboob A, Bashir R, Adnan A, Khan MU, Khurshid U, Khursheed A, et al. Food-Derived Phytochemicals from Functional Food (Allium sativum) as VEGF-R1 Inhibitors: A Novel Approach for Triple-Negative Breast Cancer Therapy. Food Bioscience. Elsevier BV; 2024;:105663 10.1016/j.fbio.2024.105663
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Dialyl-sulfide with trans-chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs induction
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Nazmeen A, Maiti S, Maiti S. Dialyl-sulfide with trans-chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs induction. Genes & Cancer. Impact Journals, LLC; 2024; 15:41-59 10.18632/genesandcancer.237
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Garlic peel extract as an antioxidant inhibits triple‐negative breast tumor growth and angiogenesis by inhibiting cyclooxygenase‐2 expression
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Dong Y, Zhang J, Xie A, Yue X, Li M, Zhou Q. Garlic peel extract as an antioxidant inhibits triple‐negative breast tumor growth and angiogenesis by inhibiting cyclooxygenase‐2 expression. Food Science & Nutrition. Wiley; 2024; 10.1002/fsn3.4320
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Synthesis, characterization and anti-cancerous evaluation of single clove garlic nanoparticles on Triple-Negative breast cancer cell lines
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Soundhararajan R, Jenin Ravindranath K, Sultana Liyakath Ali S, Srinivasan H. Synthesis, characterization and anti-cancerous evaluation of single clove garlic nanoparticles on Triple-Negative breast cancer cell lines. Materials Letters. Elsevier BV; 2024; 359:135913 10.1016/j.matlet.2024.135913
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Garlic (Allium sativum L.): A review on bio-functionality, allicin's potency and drying methodologies
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Thakur P, Dhiman A, Kumar S, Suhag R. Garlic (Allium sativum L.): A review on bio-functionality, allicin's potency and drying methodologies. South African Journal of Botany. Elsevier BV; 2024; 171:129-146 10.1016/j.sajb.2024.05.039
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Antiproliferative efficacy and mechanism of action of garlic phytochemicals-functionalized gold nanoparticles in triple-negative breast cancer cells
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Meher K, Paithankar H, Hosur RV, Lopus M. Antiproliferative efficacy and mechanism of action of garlic phytochemicals-functionalized gold nanoparticles in triple-negative breast cancer cells. Biomedical Materials. IOP Publishing; 2024; 19:035039 10.1088/1748-605x/ad3ff9
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Exploring the ROS-mediated anti-cancer potential in human triple-negative breast cancer by garlic bulb extract: A source of therapeutically active compounds
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Upadhyay S, Ahmad R, Kumar R, Ghildiyal S, Singh A, Ahmad K, et al. Exploring the ROS-mediated anti-cancer potential in human triple-negative breast cancer by garlic bulb extract: A source of therapeutically active compounds. Journal of Traditional and Complementary Medicine. Elsevier BV; 2024; 10.1016/j.jtcme.2024.04.003
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Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It
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Sheybatzadeh K, Moshtaghie SAA, Shahanipour K, Golab F. Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It. Asian Pacific Journal of Cancer Prevention. EpiSmart Science Vector Ltd; 2024; 25:893-908 10.31557/apjcp.2024.25.3.893
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Dialyl-sulfide with chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs induction
Cite
Nazmeen A, Maiti S, Maiti S. Dialyl-sulfide with chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs induction. Research Square Platform LLC; 2024; 10.21203/rs.3.rs-4023005/v1
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Allicin Overcomes Doxorubicin Resistance of Breast Cancer Cells by Targeting the Nrf2 Pathway
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Shi G, Li X, Wang W, Hou L, Yin L, Wang L. Allicin Overcomes Doxorubicin Resistance of Breast Cancer Cells by Targeting the Nrf2 Pathway. Cell Biochemistry and Biophysics. Springer Science and Business Media LLC; 2024; 10.1007/s12013-024-01215-x
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Anti-Cancer and Anti-Inflammatory Properties of Black Garlic
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Stępień AE, Trojniak J, Tabarkiewicz J. Anti-Cancer and Anti-Inflammatory Properties of Black Garlic. International Journal of Molecular Sciences. MDPI AG; 2024; 25:1801 10.3390/ijms25031801
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Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness
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Mathan SV, Singh R, Kim S, Singh SV, Singh RP. Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness. Cancers. MDPI AG; 2024; 16:378 10.3390/cancers16020378
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The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells
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Ferguson DT, Taka E, Tilghman SL, Womble T, Redmond BV, Gedeon S, et al. The Anticancer Effects of the Garlic Organosulfide Diallyl Trisulfide through the Attenuation of B[a]P-Induced Oxidative Stress, AhR Expression, and DNA Damage in Human Premalignant Breast Epithelial (MCF-10AT1) Cells. International Journal of Molecular Sciences. MDPI AG; 2024; 25:923 10.3390/ijms25020923
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Identification of potential edible spices as EGFR and EGFR mutant T790M/L858R inhibitors by structure-based virtual screening and molecular dynamics
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Ahmad Ansari I, Debnath B, Kar S, Patel HM, Debnath S, Zaki ME, et al. Identification of potential edible spices as EGFR and EGFR mutant T790M/L858R inhibitors by structure-based virtual screening and molecular dynamics. Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2023;:1-18 10.1080/07391102.2023.2223661
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Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells by downregulating MCL-1 expression through the ROS-JNK pathway
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Yang Q, Li F, Jia G, Liu R. Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells by downregulating MCL-1 expression through the ROS-JNK pathway. PLOS ONE. Public Library of Science (PLoS); 2023; 18:e0286454 10.1371/journal.pone.0286454
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Attenuative Effect of Diallyl Trisulfide on Caspase Activity in TNF-α-induced Triple Negative Breast Cancer Cells
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KANGA KJ, KANGA LH, MENDONCA P, SOLIMAN KF, FERGUSON DT, REED SL, et al. Attenuative Effect of Diallyl Trisulfide on Caspase Activity in TNF-α-induced Triple Negative Breast Cancer Cells. Anticancer Research. Anticancer Research USA Inc.; 2023; 43:2393-2405 10.21873/anticanres.16407
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Cytotoxic Effects of Nanoliposomal Cisplatin and Diallyl Disulfide on Breast Cancer and Lung Cancer Cell Lines
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Gunasekaran K, Vasamsetti BMK, Thangavelu P, Natesan K, Mujyambere B, Sundaram V, et al. Cytotoxic Effects of Nanoliposomal Cisplatin and Diallyl Disulfide on Breast Cancer and Lung Cancer Cell Lines. Biomedicines. MDPI AG; 2023; 11:1021 10.3390/biomedicines11041021
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From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment
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Astrain-Redin N, Sanmartin C, Sharma AK, Plano D. From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment. Journal of Medicinal Chemistry. American Chemical Society (ACS); 2023; 10.1021/acs.jmedchem.2c01406
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Folic Acid Functionalized Diallyl Trisulfide–Solid Lipid Nanoparticles for Targeting Triple Negative Breast Cancer
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De A, Roychowdhury P, Bhuyan NR, Ko YT, Singh SK, Dua K, et al. Folic Acid Functionalized Diallyl Trisulfide–Solid Lipid Nanoparticles for Targeting Triple Negative Breast Cancer. Molecules. MDPI AG; 2023; 28:1393 10.3390/molecules28031393
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The impact of extraction method and solvent on biological activities of garlic extract
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Septiana E, Rachman F, Prasetyoputri A, Izzati FN, Rahmawati SI, Hapsari Y, et al. The impact of extraction method and solvent on biological activities of garlic extract. AIP Conference Proceedings. AIP Publishing; 2023; 10.1063/5.0118516
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Activity-Based Proteomic Identification of the S-Thiolation Targets of Ajoene in MDA-MB-231 Breast Cancer Cells
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Kusza DA, Hunter R, Schäfer G, Smith M, Katz AA, Kaschula CH. Activity-Based Proteomic Identification of the S-Thiolation Targets of Ajoene in MDA-MB-231 Breast Cancer Cells. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2022; 10.1021/acs.jafc.2c04972
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Methods of Isolation of Active Substances from Garlic (Allium sativum L.) and Its Impact on the Composition and Biological Properties of Garlic Extracts
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Bar M, Binduga UE, Szychowski KA. Methods of Isolation of Active Substances from Garlic (Allium sativum L.) and Its Impact on the Composition and Biological Properties of Garlic Extracts. Antioxidants. MDPI AG; 2022; 11:1345 10.3390/antiox11071345
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Insight into drug sensitizing effect of diallyl disulfide and diallyl trisulfide from Allium sativum L. on paclitaxel-resistant triple-negative breast cancer cells
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Marni R, Kundrapu DB, Chakraborti A, Malla R. Insight into drug sensitizing effect of diallyl disulfide and diallyl trisulfide from Allium sativum L. on paclitaxel-resistant triple-negative breast cancer cells. Journal of Ethnopharmacology. Elsevier BV; 2022; 296:115452 10.1016/j.jep.2022.115452
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Virtual Screening and Molecular Docking Studies with Organosulfur and Flavonoid Compounds of Garlic Targeting the Estrogen Receptor Protein for the Therapy of Breast Cancer
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. Virtual Screening and Molecular Docking Studies with Organosulfur and Flavonoid Compounds of Garlic Targeting the Estrogen Receptor Protein for the Therapy of Breast Cancer. Biointerface Research in Applied Chemistry. AMG Transcend Association; 2022; 13:49 10.33263/briac131.049
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Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats
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Hahm E, Singh SV. Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats. Journal of Cancer Prevention. Korean Society of Cancer Prevention; 2022; 27:22-30 10.15430/jcp.2022.27.1.22
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Diallyl Trisulfide Induces Apoptosis in Breast Ductal Carcinoma In Situ Derived and Minimally Invasive Breast Cancer Cells
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Stan SD, Abtahi M. Diallyl Trisulfide Induces Apoptosis in Breast Ductal Carcinoma In Situ Derived and Minimally Invasive Breast Cancer Cells. Nutrients. MDPI AG; 2022; 14:1455 10.3390/nu14071455
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Herb–Drug Interaction in Inflammatory Diseases: Review of Phytomedicine and Herbal Supplements
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Annemarie A, Renner B. Herb–Drug Interaction in Inflammatory Diseases: Review of Phytomedicine and Herbal Supplements. Journal of Clinical Medicine. MDPI AG; 2022; 11:1567 10.3390/jcm11061567
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Biological properties and therapeutic applications of garlic and its components
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Melguizo-Rodríguez L, García-Recio E, Ruiz C, De Luna-Bertos E, Illescas-Montes R, Costela-Ruiz VJ. Biological properties and therapeutic applications of garlic and its components. Food & Function. Royal Society of Chemistry (RSC); 2022; 10.1039/d1fo03180e
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Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement
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Sharma M, Grewal K, Jandrotia R, Batish DR, Singh HP, Kohli RK. Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 146:112514 10.1016/j.biopha.2021.112514
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Effect of Diallyl Trisulfide on TNF-α-induced CCL2/MCP-1 Release in Genetically Different Triple-negative Breast Cancer Cells
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KANGA KJ, MENDONCA P, SOLIMAN KF, FERGUSON DT, DARLING-REED SF. Effect of Diallyl Trisulfide on TNF-α-induced CCL2/MCP-1 Release in Genetically Different Triple-negative Breast Cancer Cells. Anticancer Research. Anticancer Research USA Inc.; 2021; 41:5919-5933 10.21873/anticanres.15411
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Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer
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Malla R, Marni R, Chakraborty A, Kamal MA. Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer. Journal of Pharmaceutical Analysis. Elsevier BV; 2021; 10.1016/j.jpha.2021.11.004
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The effect of onion and garlic on non-polar heterocyclic aromatic amines (α-, β-, γ- and δ-carbolines) formation in pan-fried meat and gravy
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Śnieżek E, Szumska M, Nowak A, Janoszka B. The effect of onion and garlic on non-polar heterocyclic aromatic amines (α-, β-, γ- and δ-carbolines) formation in pan-fried meat and gravy. Food Additives & Contaminants: Part A. Informa UK Limited; 2021;:1-17 10.1080/19440049.2021.1994155
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Biological Functions of Diallyl Disulfide, a Garlic-Derived Natural Organic Sulfur Compound
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Song X, Yue Z, Nie L, Zhao P, Zhu K, Wang Q. Biological Functions of Diallyl Disulfide, a Garlic-Derived Natural Organic Sulfur Compound. Evidence-Based Complementary and Alternative Medicine. Hindawi Limited; 2021; 2021:1-13 10.1155/2021/5103626
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Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway
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Maitisha G, Aimaiti M, An Z, Li X. Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway. Molecular Biology Reports. Springer Science and Business Media LLC; 2021; 10.1007/s11033-021-06722-1
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Role of Phytochemicals in Cancer Chemoprevention: Insights
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George BP, Chandran R, Abrahamse H. Role of Phytochemicals in Cancer Chemoprevention: Insights. Antioxidants. MDPI AG; 2021; 10:1455 10.3390/antiox10091455
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Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis
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Maroni P, Bendinelli P, Fulgenzi A, Ferraretto A. Mediterranean Diet Food Components as Possible Adjuvant Therapies to Counteract Breast and Prostate Cancer Progression to Bone Metastasis. Biomolecules. MDPI AG; 2021; 11:1336 10.3390/biom11091336
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Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks
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Darling-Reed SF, Nkrumah-Elie Y, Ferguson DT, Flores-Rozas H, Mendonca P, Messeha S, et al. Diallyl Sulfide Attenuation of Carcinogenesis in Mammary Epithelial Cells through the Inhibition of ROS Formation, and DNA Strand Breaks. Biomolecules. MDPI AG; 2021; 11:1313 10.3390/biom11091313
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Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis
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Hahm E, Kim S, Mathan SV, Singh RP, Singh SV. Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis. Journal of Cancer Prevention. Korean Society of Cancer Prevention; 2021; 26:128-136 10.15430/jcp.2021.26.2.128
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The Inhibitory Effects of Organosulfide Diallyl Trisulfide on TNF‐α induced CCL2 release through MAPK/MAPK8 and NFқB/IKBKE signaling in TNBC cell lines
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Kanga K, Mendonca P, Soliman K, Darling‐Reed S. The Inhibitory Effects of Organosulfide Diallyl Trisulfide on TNF‐α induced CCL2 release through MAPK/MAPK8 and NFқB/IKBKE signaling in TNBC cell lines. The FASEB Journal. Wiley; 2021; 35 10.1096/fasebj.2021.35.s1.02349
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Anticancer Activities of Allium sativum L. Against MCF-7 and MDA-MB-231 Breast Cancer Cell Lines Mediated by Caspase-3 and Caspase-9
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Isbilen O, Volkan E. Anticancer Activities of Allium sativum L. Against MCF-7 and MDA-MB-231 Breast Cancer Cell Lines Mediated by Caspase-3 and Caspase-9. Cyprus Journal of Medical Sciences. AVES Publishing Co.; 2021; 5:305-312 10.5152/cjms.2020.1848
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Bioaccessibility of Bioactive Compounds of ‘Fresh Garlic’ and ‘Black Garlic’ through In Vitro Gastrointestinal Digestion
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Moreno-Ortega A, Pereira-Caro G, Ordóñez JL, Moreno-Rojas R, Ortíz-Somovilla V, Moreno-Rojas JM. Bioaccessibility of Bioactive Compounds of ‘Fresh Garlic’ and ‘Black Garlic’ through In Vitro Gastrointestinal Digestion. Foods. MDPI AG; 2020; 9:1582 10.3390/foods9111582
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Cytotoxic effects and apoptosis of solo black garlic (Allium sativum L.) extract on T47D breast cancer cell line
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Permatasari E, Farida , Widiyanto S. Cytotoxic effects and apoptosis of solo black garlic (Allium sativum L.) extract on T47D breast cancer cell line. THE 6TH INTERNATIONAL CONFERENCE ON BIOLOGICAL SCIENCE ICBS 2019: “Biodiversity as a Cornerstone for Embracing Future Humanity”. AIP Publishing; 2020; 10.1063/5.0015736
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Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma: Role of Notch signaling
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Elsherbiny NM, El-Sherbiny M, Zaitone SA. Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma: Role of Notch signaling. Pathology - Research and Practice. Elsevier BV; 2020; 216:153139 10.1016/j.prp.2020.153139
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Myricetin induces apoptosis mediated by oxidative stress in 4T1 and E0771 mammary cancer cells
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Knickle A, Rasmussen A, Hoskin DW. Myricetin induces apoptosis mediated by oxidative stress in 4T1 and E0771 mammary cancer cells. Molecular & Cellular Toxicology. Springer Science and Business Media LLC; 2020; 16:283-289 10.1007/s13273-020-00089-3
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Synergistic effects of S-alkenylmercaptocysteine (CySSR) species derived from Allium tissue and selenium on inducing apoptosis in ER− breast cancer cells
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Zhang W, Tocmo R, Parkin KL. Synergistic effects of S-alkenylmercaptocysteine (CySSR) species derived from Allium tissue and selenium on inducing apoptosis in ER− breast cancer cells. Journal of Functional Foods. Elsevier BV; 2020; 65:103786 10.1016/j.jff.2020.103786
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Onion and Garlic Intake and Breast Cancer, a Case-Control Study in Puerto Rico
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Desai G, Schelske-Santos M, Nazario CM, Rosario-Rosado RV, Mansilla-Rivera I, Ramírez-Marrero F, et al. Onion and Garlic Intake and Breast Cancer, a Case-Control Study in Puerto Rico. Nutrition and Cancer. Informa UK Limited; 2019; 72:791-800 10.1080/01635581.2019.1651349
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Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest
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Shaban AM. Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest. Journal of Applied Pharmaceutical Science. Journal of Applied Pharmaceutical Science; 2018; 8:142-150 10.7324/japs.2018.8920
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Antioxidant Activity of Spices and Their Impact on Human Health: A Review
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Yashin A, Yashin Y, Xia X, Nemzer B. Antioxidant Activity of Spices and Their Impact on Human Health: A Review. Antioxidants. MDPI AG; 2017; 6:70 10.3390/antiox6030070
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P4 Diallyl Trisulfides, a garlic-derived organosulfur compound, attenuates vascular metastasis of hypoxic breast cancer cells by targeting the thioredoxin system
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Wei Z, Lu Y. P4 Diallyl Trisulfides, a garlic-derived organosulfur compound, attenuates vascular metastasis of hypoxic breast cancer cells by targeting the thioredoxin system. Biochemical Pharmacology. Elsevier BV; 2017; 139:125-126 10.1016/j.bcp.2017.06.005
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Anti-cancer potential of a mix of natural extracts of turmeric, ginger and garlic: A cell-based study
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Vemuri SK, Banala RR, Subbaiah G, Srivastava SK, Reddy AG, Malarvili T. Anti-cancer potential of a mix of natural extracts of turmeric, ginger and garlic: A cell-based study. Egyptian Journal of Basic and Applied Sciences. Informa UK Limited; 2017; 4:332-344 10.1016/j.ejbas.2017.07.005
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Consumption of garlic and lemon aqueous extracts combination reduces tumor burden by angiogenesis inhibition, apoptosis induction, and immune system modulation
Cite
Talib WH. Consumption of garlic and lemon aqueous extracts combination reduces tumor burden by angiogenesis inhibition, apoptosis induction, and immune system modulation. Nutrition. Elsevier BV; 2017; 43-44:89-97 10.1016/j.nut.2017.06.015
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Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel
Cite
IZDEBSKA M, GRZANKA D, GAGAT M, HAŁAS-WIŚNIEWSKA M, GRZANKA A. Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel. Oncology Reports. Spandidos Publications; 2016; 35:3084-3093 10.3892/or.2016.4628
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Clinical Evidence of Herbal Drugs As Perpetrators of Pharmacokinetic Drug Interactions
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Hermann R, von Richter O. Clinical Evidence of Herbal Drugs As Perpetrators of Pharmacokinetic Drug Interactions. Planta Medica. Georg Thieme Verlag KG; 2012; 78:1458-1477 10.1055/s-0032-1315117
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Cooked garlic and antioxidant activity: Correlation with organosulfur compound composition
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Locatelli D, Nazareno M, Fusari C, Camargo A. Cooked garlic and antioxidant activity: Correlation with organosulfur compound composition. Food Chemistry. Elsevier BV; 2017; 220:219-224 10.1016/j.foodchem.2016.10.001
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Associations between DietaryAlliumVegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study
Cite
Pourzand A, Tajaddini A, Pirouzpanah S, Asghari-Jafarabadi M, Samadi N, Ostadrahimi A, et al. Associations between DietaryAlliumVegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study. Journal of Breast Cancer. Korean Breast Cancer Society; 2016; 19:292 10.4048/jbc.2016.19.3.292
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Deodorization of Garlic Breath by Foods, and the Role of Polyphenol Oxidase and Phenolic Compounds
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Mirondo R, Barringer S. Deodorization of Garlic Breath by Foods, and the Role of Polyphenol Oxidase and Phenolic Compounds. Journal of Food Science. Wiley; 2016; 81:C2425-C2430 10.1111/1750-3841.13439
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Lactate dehydrogenase downregulation mediates the inhibitory effect of diallyl trisulfide on proliferation, metastasis, and invasion in triple-negative breast cancer
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Cheng S, Yang Y, Ting K, Wen S, Viswanadha VP, Huang C, et al. Lactate dehydrogenase downregulation mediates the inhibitory effect of diallyl trisulfide on proliferation, metastasis, and invasion in triple-negative breast cancer. Environmental Toxicology. Wiley; 2016; 32:1390-1398 10.1002/tox.22333
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Differential pro-apoptotic effect of allicin in oestrogen receptor-positive or -negative human breast cancer cells
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Kim K, Cho S, Kim B, Pyo S. Differential pro-apoptotic effect of allicin in oestrogen receptor-positive or -negative human breast cancer cells. Journal of Functional Foods. Elsevier BV; 2016; 25:341-353 10.1016/j.jff.2016.06.019
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Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases
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Yun E, Song K, Shin S, Kim S, Heo J, Kweon G, et al. Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases. Oncotarget. Impact Journals, LLC; 2016; 7:49961-49971 10.18632/oncotarget.10266
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Heat Inactivation of Garlic (Allium sativum) Extract Abrogates Growth Inhibition of HeLa Cells
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Chintapalli R, Murray MJJ, Murray JT. Heat Inactivation of Garlic (Allium sativum) Extract Abrogates Growth Inhibition of HeLa Cells. Nutrition and Cancer. Informa UK Limited; 2016; 68:818-826 10.1080/01635581.2016.1171885
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Allicin inhibits lymphangiogenesis through suppressing activation of vascular endothelial growth factor (VEGF) receptor
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Wang W, Du Z, Nimiya Y, Sukamtoh E, Kim D, Zhang G. Allicin inhibits lymphangiogenesis through suppressing activation of vascular endothelial growth factor (VEGF) receptor. The Journal of Nutritional Biochemistry. Elsevier BV; 2016; 29:83-89 10.1016/j.jnutbio.2015.11.004
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A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans
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Charron CS, Dawson HD, Albaugh GP, Solverson PM, Vinyard BT, Solano-Aguilar GI, et al. A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans. The Journal of Nutrition. Oxford University Press (OUP); 2015; 145:2448-2455 10.3945/jn.115.215392
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Herb‐Drug Interactions in Oncology: Focus on Mechanisms of Induction
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Meijerman I, Beijnen JH, Schellens JH. Herb‐Drug Interactions in Oncology: Focus on Mechanisms of Induction. The Oncologist. Wiley; 2006; 11:742-752 10.1634/theoncologist.11-7-742
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The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells
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Kaschula CH, Hunter R, Cotton J, Tuveri R, Ngarande E, Dzobo K, et al. The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells. Molecular Carcinogenesis. Wiley; 2015; 55:1213-1228 10.1002/mc.22364
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Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways
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Liu Y, Zhu P, Wang Y, Wei Z, Tao L, Zhu Z, et al. Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0123781 10.1371/journal.pone.0123781
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Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α
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Lee CG, Lee H, Kim B, Rhee D, Pyo S. Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α. Journal of Functional Foods. Elsevier BV; 2015; 15:172-185 10.1016/j.jff.2015.03.017
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Garlic and Onions: Their Cancer Prevention Properties
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Nicastro HL, Ross SA, Milner JA. Garlic and Onions: Their Cancer Prevention Properties. Cancer Prevention Research. American Association for Cancer Research (AACR); 2015; 8:181-189 10.1158/1940-6207.capr-14-0172
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Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a
Cite
Xiao X, Chen B, Liu X, Liu P, Zheng G, Ye F, et al. Diallyl Disulfide Suppresses SRC/Ras/ERK Signaling-Mediated Proliferation and Metastasis in Human Breast Cancer by Up-Regulating miR-34a. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e112720 10.1371/journal.pone.0112720
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Abstract 227: Estrogen receptor-α and tumor initiating cells are novel targets of diallyl trisulfide in breast cancer cells
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Hahm E, Kim S, Singh SV. Abstract 227: Estrogen receptor-α and tumor initiating cells are novel targets of diallyl trisulfide in breast cancer cells. Prevention Research. American Association for Cancer Research; 2014; 10.1158/1538-7445.am2014-227
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Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A)
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McCaskill ML, Rogan E, Thomas RD. Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A). Steroids. Elsevier BV; 2014; 92:96-100 10.1016/j.steroids.2014.09.005
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Exposure of breast cancer cells to a subcytotoxic dose of apigenin causes growth inhibition, oxidative stress, and hypophosphorylation of Akt
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Harrison ME, Power Coombs MR, Delaney LM, Hoskin DW. Exposure of breast cancer cells to a subcytotoxic dose of apigenin causes growth inhibition, oxidative stress, and hypophosphorylation of Akt. Experimental and Molecular Pathology. Elsevier BV; 2014; 97:211-217 10.1016/j.yexmp.2014.07.006
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Determination of Phenolic Compounds in Artichoke, Garlic and Spinach by Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry
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Alarcón-Flores MI, Romero-González R, Martínez Vidal JL, Garrido Frenich A. Determination of Phenolic Compounds in Artichoke, Garlic and Spinach by Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry. Food Analytical Methods. Springer Science and Business Media LLC; 2014; 7:2095-2106 10.1007/s12161-014-9852-4
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Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds
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Trio PZ, You S, He X, He J, Sakao K, Hou D. Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds. Food & Function. Royal Society of Chemistry (RSC); 2014; 5:833 10.1039/c3fo60479a
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Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells
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Hahm E, Singh SV. Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2014; 144:47-57 10.1007/s10549-014-2841-x
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Potential therapeutic effects of functionally active compounds isolated from garlic
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Yun H, Ban JO, Park K, Lee CK, Jeong H, Han SB, et al. Potential therapeutic effects of functionally active compounds isolated from garlic. Pharmacology & Therapeutics. Elsevier BV; 2014; 142:183-195 10.1016/j.pharmthera.2013.12.005
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Molecular mechanisms for the anti-cancer effects of diallyl disulfide
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Yi L, Su Q. Molecular mechanisms for the anti-cancer effects of diallyl disulfide. Food and Chemical Toxicology. Elsevier BV; 2013; 57:362-370 10.1016/j.fct.2013.04.001
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Critical role for reactive oxygen species in apoptosis induction and cell migration inhibition by diallyl trisulfide, a cancer chemopreventive component of garlic
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Chandra-Kuntal K, Lee J, Singh SV. Critical role for reactive oxygen species in apoptosis induction and cell migration inhibition by diallyl trisulfide, a cancer chemopreventive component of garlic. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 138:69-79 10.1007/s10549-013-2440-2
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HPLC–MTT assay: Anticancer activity of aqueous garlic extract is from allicin
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Lee J, Gupta S, Huang J, Jayathilaka LP, Lee B. HPLC–MTT assay: Anticancer activity of aqueous garlic extract is from allicin. Analytical Biochemistry. Elsevier BV; 2013; 436:187-189 10.1016/j.ab.2013.01.033
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Diallyl Disulfide-Induced Apoptosis in a Breast-Cancer Cell Line (MCF-7) May Be Caused by Inhibition of Histone Deacetylation
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Altonsy MO, Habib TN, Andrews SC. Diallyl Disulfide-Induced Apoptosis in a Breast-Cancer Cell Line (MCF-7) May Be Caused by Inhibition of Histone Deacetylation. Nutrition and Cancer. Informa UK Limited; 2012; 64:1251-1260 10.1080/01635581.2012.721156
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Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1
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Na H, Kim E, Choi M, Park J, Kim D, Surh Y. Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1. Biochemical Pharmacology. Elsevier BV; 2012; 84:1241-1250 10.1016/j.bcp.2012.08.024
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Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells
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Nkrumah-Elie YM, Reuben JS, Hudson A, Taka E, Badisa R, Ardley T, et al. Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells. Food and Chemical Toxicology. Elsevier BV; 2012; 50:2524-2530 10.1016/j.fct.2012.04.010
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Dangerous Combinations: Ingestible CAM Supplement Use During Chemotherapy in Patients with Ovarian Cancer
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Andersen MR, Sweet E, Lowe KA, Standish LJ, Drescher CW, Goff BA. Dangerous Combinations: Ingestible CAM Supplement Use During Chemotherapy in Patients with Ovarian Cancer. The Journal of Alternative and Complementary Medicine. Mary Ann Liebert Inc; 2013; 19:714-720 10.1089/acm.2012.0295
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Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases
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Bagrel . Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases. International Journal of Oncology. Spandidos Publications; 2011; 38 10.3892/ijo.2011.913
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Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats
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Alkreathy H, Damanhouri ZA, Ahmed N, Slevin M, Ali SS, Osman AM. Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats. Food and Chemical Toxicology. Elsevier BV; 2010; 48:951-956 10.1016/j.fct.2010.01.005
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Influence of Cooking Methods on Antioxidant Activity of Vegetables
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Jiménez-Monreal AM, García-Diz L, Martínez-Tomé M, Mariscal M, Murcia MA. Influence of Cooking Methods on Antioxidant Activity of Vegetables. Journal of Food Science. Wiley; 2009; 74:H97-H103 10.1111/j.1750-3841.2009.01091.x
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Allium vegetables intake and endometrial cancer risk
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Galeone C, Pelucchi C, Dal Maso L, Negri E, Montella M, Zucchetto A, et al. Allium vegetables intake and endometrial cancer risk. Public Health Nutrition. Cambridge University Press (CUP); 2009; 12:1576-1579 10.1017/s1368980008003820
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Comparisons of food intake between breast cancer patients and controls in Korean women
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Kim E, Hong Y, Jeon H, Sung M, Sung C. Comparisons of food intake between breast cancer patients and controls in Korean women. Nutrition Research and Practice. The Korean Nutrition Society and The Korean Society of Community Nutrition; 2007; 1:237 10.4162/nrp.2007.1.3.237
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S-Allylcysteine reduces breast tumor cell adhesion and invasion
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Gapter LA, Yuin OZ, Ng K. S-Allylcysteine reduces breast tumor cell adhesion and invasion. Biochemical and Biophysical Research Communications. Elsevier BV; 2008; 367:446-451 10.1016/j.bbrc.2007.12.175
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Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines
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Nakagawa H. Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines. Carcinogenesis. Oxford University Press (OUP); 2001; 22:891-897 10.1093/carcin/22.6.891
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Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neuin HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
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Way T, Kao M, Lin J. Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neuin HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway. Journal of Biological Chemistry. American Society for Biochemistry & Molecular Biology (ASBMB); 2003; 279:4479-4489 10.1074/jbc.m305529200
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Onion and garlic use and human cancer
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Galeone C, Pelucchi C, Levi F, Negri E, Franceschi S, Talamini R, et al. Onion and garlic use and human cancer. The American Journal of Clinical Nutrition. Oxford University Press (OUP); 2006; 84:1027-1032 10.1093/ajcn/84.5.1027
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Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-71
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LEI X, YAO S, ZU X, HUANG Z, LIU L, ZHONG M, et al. Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-71. Acta Pharmacologica Sinica. Springer Science and Business Media LLC; 2008; 29:1233-1239 10.1111/j.1745-7254.2008.00851.x