Tag: epigenetic

News

02/29/16

Apigenin reduces TN proliferation & growth through epigenetic changes

09/19/12

Prenatal estrogen or high fat diet exposure increases BC risk in pups

09/18/10

Resveratrol can reduce breast cancer-promoting DNA damage

Studies

• Epigenetic Profiles of Triple-Negative Breast Cancers of African American and White Females Cite
  Ensenyat-Mendez M, Solivellas-Pieras M, Llinàs-Arias P, Íñiguez-Muñoz S, Baker JL, Marzese DM, et al. Epigenetic Profiles of Triple-Negative Breast Cancers of African American and White Females. JAMA Network Open. American Medical Association (AMA); 2023; 6:e2335821 10.1001/jamanetworkopen.2023.35821
• Mechanisms Of Breast Cancer Progression Induced BY Environment-Polluting ARYL Hydrocarbon Receptor Agonists Cite
  Miret NV, Pontillo CA, Buján S, Chiappini FA, Randi AS. Mechanisms Of Breast Cancer Progression Induced BY Environment-Polluting ARYL Hydrocarbon Receptor Agonists. Biochemical Pharmacology. Elsevier BV; 2023;:115773 10.1016/j.bcp.2023.115773
• Latest advances in epigenetic mechanisms of nutrients in breast cancer and the relation of homocysteine mechanism Cite
  Kocatürk RR, Atalay VE. Latest advances in epigenetic mechanisms of nutrients in breast cancer and the relation of homocysteine mechanism. Food and Health. TMR Publishing Group; 2023; 5:8 10.53388/fh2023008
• Epigenetic Regulation in Chromium-, Nickel- and Cadmium-Induced Carcinogenesis Cite
  Zhao L, Islam R, Wang Y, Zhang X, Liu L. Epigenetic Regulation in Chromium-, Nickel- and Cadmium-Induced Carcinogenesis. Cancers. MDPI AG; 2022; 14:5768 10.3390/cancers14235768
• The effects of endocrine-disrupting chemicals (EDCs) on the epigenome-A short overview Cite
  Buha A, Manic L, Maric D, Tinkov A, Skolny A, Antonijevic B, et al. The effects of endocrine-disrupting chemicals (EDCs) on the epigenome-A short overview. Toxicology Research and Application. SAGE Publications; 2022; 6:239784732211158 10.1177/23978473221115817
• Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition Cite
  Sharma M, Tollefsbol TO. Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. Experimental Cell Research. Elsevier BV; 2022; 416:113160 10.1016/j.yexcr.2022.113160
• Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association Cite
  Javaid A, Zahra D, Rashid F, Mashraqi M, Alzamami A, Khurshid M, et al. Regulation of micro-RNA, epigenetic factor by natural products for the treatment of cancers: Mechanistic insight and translational Association. Saudi Journal of Biological Sciences. Elsevier BV; 2022; 10.1016/j.sjbs.2022.03.005
• Role of Flavonoids as Epigenetic Modulators in Cancer Prevention and Therapy Cite
  Fatima N, Baqri SSR, Bhattacharya A, Koney NK, Husain K, Abbas A, et al. Role of Flavonoids as Epigenetic Modulators in Cancer Prevention and Therapy. Frontiers in Genetics. Frontiers Media SA; 2021; 12 10.3389/fgene.2021.758733
• Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway Cite
  Akhtar S, Hourani S, Therachiyil L, Al-Dhfyan A, Agouni A, Zeidan A, et al. Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway. Seminars in Cancer Biology. Elsevier BV; 2020; 10.1016/j.semcancer.2020.08.014
• Abstract 2440: The epigenetic influence of maternal diet on prevention of high-fat diet induced obesity and breast cancer in later life Cite
  Li Y, Chen M, Tollefsbol T. Abstract 2440: The epigenetic influence of maternal diet on prevention of high-fat diet induced obesity and breast cancer in later life. Molecular and Cellular Biology / Genetics. American Association for Cancer Research; 2020; 10.1158/1538-7445.am2020-2440
• The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients Cite
  Sehl ME, Carroll JE, Horvath S, Bower JE. The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients. npj Breast Cancer. Springer Science and Business Media LLC; 2020; 6 10.1038/s41523-020-0161-3
• Flavonoids in Cancer Metastasis Cite
  Liskova A, Koklesova L, Samec M, Smejkal K, Samuel SM, Varghese E, et al. Flavonoids in Cancer Metastasis. Cancers. MDPI AG; 2020; 12:1498 10.3390/cancers12061498
• Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer Cite
  Selvakumar P, Badgeley A, Murphy P, Anwar H, Sharma U, Lawrence K, et al. Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer. Nutrients. MDPI AG; 2020; 12:761 10.3390/nu12030761
• Is breast cancer a result of epigenetic responses to traffic-related air pollution? A review of the latest evidence Cite
  Sahay D, Terry MB, Miller R. Is breast cancer a result of epigenetic responses to traffic-related air pollution? A review of the latest evidence. Epigenomics. Future Medicine Ltd; 2019; 11:701-714 10.2217/epi-2018-0158
• Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential Cite
  Cava C, Bertoli G, Castiglioni I. Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential. BMC Systems Biology. Springer Science and Business Media LLC; 2015; 9 10.1186/s12918-015-0211-x
• The Role of Dietary Extra Virgin Olive Oil and Corn Oil on the Alteration of Epigenetic Patterns in the Rat DMBA-Induced Breast Cancer Model Cite
  Rodríguez-Miguel C, Moral R, Escrich R, Vela E, Solanas M, Escrich E. The Role of Dietary Extra Virgin Olive Oil and Corn Oil on the Alteration of Epigenetic Patterns in the Rat DMBA-Induced Breast Cancer Model. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0138980 10.1371/journal.pone.0138980
• Epigenetic activities of flavonoids in the prevention and treatment of cancer Cite
  Busch C, Burkard M, Leischner C, Lauer UM, Frank J, Venturelli S. Epigenetic activities of flavonoids in the prevention and treatment of cancer. Clinical Epigenetics. Springer Science and Business Media LLC; 2015; 7 10.1186/s13148-015-0095-z
• Molecular mechanisms of pharmacological doses of ascorbate on cancer cells Cite
  Venturelli S, Sinnberg TW, Niessner H, Busch C. Molecular mechanisms of pharmacological doses of ascorbate on cancer cells. Wiener Medizinische Wochenschrift. Springer Science and Business Media LLC; 2015; 165:251-257 10.1007/s10354-015-0356-7
• Epigenetic effects of selenium and their implications for health Cite
  Speckmann B, Grune T. Epigenetic effects of selenium and their implications for health. Epigenetics. Informa UK Limited; 2015; 10:179-190 10.1080/15592294.2015.1013792
• Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition Cite
  Tortorella SM, Royce SG, Licciardi PV, Karagiannis TC. Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition. Antioxidants & Redox Signaling. Mary Ann Liebert Inc; 2015; 22:1382-1424 10.1089/ars.2014.6097
• Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissues Cite
  Llanos AA, Dumitrescu RG, Brasky TM, Liu Z, Mason JB, Marian C, et al. Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissues. Carcinogenesis. Oxford University Press (OUP); 2014; 36:60-67 10.1093/carcin/bgu219
• Effects of selenium compounds on proliferation and epigenetic marks of breast cancer cells Cite
  de Miranda JX, Andrade FdO, Conti Ad, Dagli MLZ, Moreno FS, Ong TP. Effects of selenium compounds on proliferation and epigenetic marks of breast cancer cells. Journal of Trace Elements in Medicine and Biology. Elsevier BV; 2014; 28:486-491 10.1016/j.jtemb.2014.06.017
• Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development Cite
  Dhimolea E, Wadia PR, Murray TJ, Settles ML, Treitman JD, Sonnenschein C, et al. Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e99800 10.1371/journal.pone.0099800
• Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo Cite
  Bhan A, Hussain I, Ansari KI, Bobzean SA, Perrotti LI, Mandal SS. Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2014; 141:160-170 10.1016/j.jsbmb.2014.02.002
• Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer Cite
  Fontana L, Adelaiye RM, Rastelli AL, Miles KM, Ciamporcero E, Longo VD, et al. Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer. Oncotarget. Impact Journals, LLC; 2013; 4:2451-2461 10.18632/oncotarget.1586
• Bisphenol A: A Model Endocrine Disrupting Chemical With a New Potential Mechanism of Action Cite
  Nagel SC, Bromfield JJ. Bisphenol A: A Model Endocrine Disrupting Chemical With a New Potential Mechanism of Action. Endocrinology. The Endocrine Society; 2013; 154:1962-1964 10.1210/en.2013-1370
• Epigenetic impact of dietary isothiocyanates in cancer chemoprevention Cite
  Gerhauser C. Epigenetic impact of dietary isothiocyanates in cancer chemoprevention. Current Opinion in Clinical Nutrition and Metabolic Care. Ovid Technologies (Wolters Kluwer Health); 2013; 16:405-410 10.1097/mco.0b013e328362014e
• Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents Cite
  POGRIBNY IP, TRYNDYAK VP, POGRIBNA M, SHPYLEVA S, SURRATT G, COSTA GGD, et al. Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents. International Journal of Oncology. Spandidos Publications; 2013; 42:1822-1832 10.3892/ijo.2013.1855
• Resveratrol activates the histone H2B ubiquitin ligase, RNF20, in MDA-MB-231 breast cancer cells Cite
  Lin C, Hsiao W, Wright DE, Hsu C, Lo Y, Wang Hsu G, et al. Resveratrol activates the histone H2B ubiquitin ligase, RNF20, in MDA-MB-231 breast cancer cells. Journal of Functional Foods. Elsevier BV; 2013; 5:790-800 10.1016/j.jff.2013.01.025
• Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9 Cite
  Jiang M, Huang O, Zhang X, Xie Z, Shen A, Liu H, et al. Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9. Molecules. MDPI AG; 2013; 18:701-720 10.3390/molecules18010701
• High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring Cite
  de Assis S, Warri A, Cruz MI, Laja O, Tian Y, Zhang B, et al. High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring. Nature Communications. Springer Science and Business Media LLC; 2012; 3 10.1038/ncomms2058
• Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer Cite
  Stone A, Valdés-Mora F, Gee JMW, Farrow L, McClelland RA, Fiegl H, et al. Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e40466 10.1371/journal.pone.0040466
• Mechanisms of action of isothiocyanates in cancer chemoprevention: an update Cite
  Navarro SL, Li F, Lampe JW. Mechanisms of action of isothiocyanates in cancer chemoprevention: an update. Food & Function. Royal Society of Chemistry (RSC); 2011; 2:579 10.1039/c1fo10114e
• Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1 Cite
  Zeng H, Irwin ML, Lu L, Risch H, Mayne S, Mu L, et al. Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2011; 133:127-135 10.1007/s10549-011-1716-7
• Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells Cite
  Papoutsis AJ, Lamore SD, Wondrak GT, Selmin OI, Romagnolo DF. Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells. The Journal of Nutrition. Oxford University Press (OUP); 2010; 140:1607-1614 10.3945/jn.110.123422
• In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer Cite
  Doherty LF, Bromer JG, Zhou Y, Aldad TS, Taylor HS. In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer. Hormones and Cancer. Springer Science and Business Media LLC; 2010; 1:146-155 10.1007/s12672-010-0015-9
• Abstract LB-93: The epigenetic basis of the tumorigenic action of retinoic acid Cite
  Rossetti S, Ren M, Somenzi G, Tagliavacca L, Sacchi N. Abstract LB-93: The epigenetic basis of the tumorigenic action of retinoic acid. Cellular and Molecular Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-lb-93
• Role of melatonin in the epigenetic regulation of breast cancer Cite
  Korkmaz A, Sanchez-Barcelo EJ, Tan D, Reiter RJ. Role of melatonin in the epigenetic regulation of breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2008; 115:13-27 10.1007/s10549-008-0103-5