Tag: cholesterol
Cholesterol: A waxy, fat-like substance that occurs naturally in all parts of the body, including the blood. Total cholesterol consists of high-density lipoprotein (HDL, the "good" cholesterol), low-density lipoprotein (LDL, the "bad" cholesterol), triglycerides and lipoprotein(a) (Lp(a) cholesterol).
Articles
News
- 09/28/22
- High cholesterol promotes breast cancer metastasis by increasing vascular invasion
- 07/08/19
- Consuming bacon drippings linked to increased metastasis in mice
- 04/16/16
- Some factors promoting breast cancer metastasis
- 02/21/16
- HDL from BC patients with type 2 diabetes can promote metastasis
Foods
Studies
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Association between triglyceride glucose index and breast cancer in 142,184 Chinese adults: findings from the REACTION study
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Wu X, Wang S, Lin L, Jia X, Hu C, Qi H, et al. Association between triglyceride glucose index and breast cancer in 142,184 Chinese adults: findings from the REACTION study. Frontiers in Endocrinology. Frontiers Media SA; 2024; 15 10.3389/fendo.2024.1321622
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Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer
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Hillis AL, Martin TD, Manchester HE, Högström J, Zhang N, Lecky E, et al. Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer. Cancer Research. American Association for Cancer Research (AACR); 2024; 10.1158/0008-5472.can-24-0970
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Statins in breast cancer treatment and management: a mini-review of potential benefits and clinical implications
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Aftab A, Hussain T, Hussain R, Shah HH, Habiba U, Haque MA. Statins in breast cancer treatment and management: a mini-review of potential benefits and clinical implications. International Journal of Surgery: Global Health. Ovid Technologies (Wolters Kluwer Health); 2024; 7 10.1097/gh9.0000000000000461
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Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression
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Park JH, Mortaja M, Son HG, Zhao X, Sloat LM, Azin M, et al. Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nature Communications. Springer Science and Business Media LLC; 2024; 15 10.1038/s41467-024-48441-8
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Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis
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Bucci T, Gue Y, Dobson R, Palmieri C, Pignatelli P, Lip GYH. Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis. Clinical and Experimental Medicine. Springer Science and Business Media LLC; 2024; 24 10.1007/s10238-024-01395-z
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Investigating the Relationship between Body Mass Index, Cholesterol, and Cancer in United States Adults: A Cross-Sectional Study
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Martinović A, Axon DR. Investigating the Relationship between Body Mass Index, Cholesterol, and Cancer in United States Adults: A Cross-Sectional Study. Diseases. MDPI AG; 2024; 12:120 10.3390/diseases12060120
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282P Metabolic syndrome and survival in breast cancer survivors: A systematic review and meta-analysis
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Borup H, Borgquist S, Harborg K. 282P Metabolic syndrome and survival in breast cancer survivors: A systematic review and meta-analysis. ESMO Open. Elsevier BV; 2024; 9:103340 10.1016/j.esmoop.2024.103340
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Breast cancer incidence and mortality by metabolic syndrome and obesity: The Women’s Health Initiative
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Chlebowski RT, Aragaki AK, Pan K, Simon MS, Neuhouser ML, Haque R, et al. Breast cancer incidence and mortality by metabolic syndrome and obesity: The Women’s Health Initiative. Cancer. Wiley; 2024; 10.1002/cncr.35318
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Statin use and risks of breast cancer recurrence and mortality
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Guo H, Malone KE, Heckbert SR, Li CI. Statin use and risks of breast cancer recurrence and mortality. Cancer. Wiley; 2024; 10.1002/cncr.35362
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Association between pathologic complete response and biochemical indicators after neoadjuvant therapy for HER2-positive breast cancer
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Chen W, Zhang J, Li F, Chen Z, Li J, Lu D. Association between pathologic complete response and biochemical indicators after neoadjuvant therapy for HER2-positive breast cancer. World Journal of Surgical Oncology. Springer Science and Business Media LLC; 2024; 22 10.1186/s12957-024-03366-w
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Post-surgery statin use contributes to favorable outcomes in patients with early breast cancer
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Giorello MB, Marks MP, Osinalde TM, Padin MdR, Wernicke A, Calvo JC, et al. Post-surgery statin use contributes to favorable outcomes in patients with early breast cancer. Cancer Epidemiology. Elsevier BV; 2024; 90:102573 10.1016/j.canep.2024.102573
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The association between oxidized low-density lipoprotein and cancer: An emerging targeted therapeutic approach?
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Moghadam SG, Pour ME, Alavizadeh SH, Kesharwani P, Sahebkar A. The association between oxidized low-density lipoprotein and cancer: An emerging targeted therapeutic approach?. Bioorganic & Medicinal Chemistry Letters. Elsevier BV; 2024;:129762 10.1016/j.bmcl.2024.129762
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Possible interactions between selected food processing and medications
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Poli G, Bologna E, Saguy IS. Possible interactions between selected food processing and medications. Frontiers in Nutrition. Frontiers Media SA; 2024; 11 10.3389/fnut.2024.1380010
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Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
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Li C, Stražar M, Mohamed AM, Pacheco JA, Walker RL, Lebar T, et al. Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria. Cell. Elsevier BV; 2024; 10.1016/j.cell.2024.03.014
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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis
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Freitas FP, Alborzinia H, dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, et al. 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis. Nature. Springer Science and Business Media LLC; 2024; 626:401-410 10.1038/s41586-023-06878-9
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Regulating Cholesterol in Tumorigenesis: A Novel Paradigm for Tumor Nanotherapeutics
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Wu H, Wu X, Zhao M, Yan J, Li C, Zhang Z, et al. Regulating Cholesterol in Tumorigenesis: A Novel Paradigm for Tumor Nanotherapeutics. International Journal of Nanomedicine. Informa UK Limited; 2024; Volume 19:1055-1076 10.2147/ijn.s439828
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Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer
Cite
Hillis AL, Martin TD, Manchester HE, Hogstrom JM, Zhang N, Lecky E, et al. Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer. Cold Spring Harbor Laboratory; 2024; 10.1101/2024.01.16.575899
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Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer
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Li L, Wang H, Zhang S, Gao S, Lu X, Pan Y, et al. Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer. International Journal of Surgery. Ovid Technologies (Wolters Kluwer Health); 2024; 10.1097/js9.0000000000001582
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Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer
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Murto MO, Simolin N, Arponen O, Siltari A, Artama M, Visvanathan K, et al. Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer. JAMA Network Open. American Medical Association (AMA); 2023; 6:e2343861 10.1001/jamanetworkopen.2023.43861
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Circulating levels of biomarkers and risk of ductal carcinoma in situ of the breast in the UK Biobank study
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Peila R, Rohan TE. Circulating levels of biomarkers and risk of ductal carcinoma in situ of the breast in the UK Biobank study. International Journal of Cancer. Wiley; 2023; 10.1002/ijc.34795
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Statin use is associated with a lower risk of mortality in patients with malignant breast cancer treated with anthracyclines. A global federated health database analysis
Cite
Bucci T, Gue Y, Dobson R, Palmieri C, Pignatelli P, Cross M, et al. Statin use is associated with a lower risk of mortality in patients with malignant breast cancer treated with anthracyclines. A global federated health database analysis. European Heart Journal. Oxford University Press (OUP); 2023; 44 10.1093/eurheartj/ehad655.2876
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Phytosterols activating nuclear receptors are involving in steroid hormone-dependent cancers: Myth or fact?
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Bakrim S, El Omari N, Khan EJ, Khalid A, Abdalla AN, Chook JB, et al. Phytosterols activating nuclear receptors are involving in steroid hormone-dependent cancers: Myth or fact?. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 169:115783 10.1016/j.biopha.2023.115783
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Icosapent ethyl supplementation rapidly reduces cardiovascular disease risk markers and improves plasma and lipoprotein lipidome reducing their atherogenicity in humans
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Äikäs L, Hermansson M, Kovanen P, Öörni K. Icosapent ethyl supplementation rapidly reduces cardiovascular disease risk markers and improves plasma and lipoprotein lipidome reducing their atherogenicity in humans. Atherosclerosis. Elsevier BV; 2023; 379:S54 10.1016/j.atherosclerosis.2023.06.224
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Circulating 27-hydroxycholesterol, lipids, and steroid hormones in breast cancer risk: a nested case–control study of the Multiethnic Cohort Study
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DeRouen MC, Yang J, Li Y, Franke AA, Tome AN, White KK, et al. Circulating 27-hydroxycholesterol, lipids, and steroid hormones in breast cancer risk: a nested case–control study of the Multiethnic Cohort Study. Breast Cancer Research. Springer Science and Business Media LLC; 2023; 25 10.1186/s13058-023-01693-6
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Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins
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Stouth DW, Lebeau PF, Austin RC. Repurposing Two Old Friends to Fight Cancer: Caffeine and Statins. Cancer Research. American Association for Cancer Research (AACR); 2023; 83:2091-2092 10.1158/0008-5472.can-23-1066
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Association of statin use and increase in lipoprotein(a): a real-world database research
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Feng T, Li Y, Xue X, Yang W, Li Q, Huang Y, et al. Association of statin use and increase in lipoprotein(a): a real-world database research. European Journal of Medical Research. Springer Science and Business Media LLC; 2023; 28 10.1186/s40001-023-01155-x
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Is cholesterol a risk factor for breast cancer incidence and outcome?
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Ben Hassen C, Goupille C, Vigor C, Durand T, Guéraud F, Silvente-Poirot S, et al. Is cholesterol a risk factor for breast cancer incidence and outcome?. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2023;:106346 10.1016/j.jsbmb.2023.106346
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Association of serum lipid levels and clinical outcomes in early breast cancer patients
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Dong S, Yu J, Chen X, Shen K. Association of serum lipid levels and clinical outcomes in early breast cancer patients. Therapeutic Advances in Medical Oncology. SAGE Publications; 2023; 15:175883592311770 10.1177/17588359231177004
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Abstract 743: Association between physical activity and lipid profile among breast cancer survivors
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Cho HJ, Kang M, Kim Z, Youn HJ, Cho J, Min JW, et al. Abstract 743: Association between physical activity and lipid profile among breast cancer survivors. Cancer Research. American Association for Cancer Research (AACR); 2023; 83:743-743 10.1158/1538-7445.am2023-743
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Cholesterol and breast cancer risk: a cohort study using health insurance claims and health checkup databases
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Narii N, Zha L, Komatsu M, Kitamura T, Sobue T, Ogawa T. Cholesterol and breast cancer risk: a cohort study using health insurance claims and health checkup databases. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2023; 10.1007/s10549-023-06917-z
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The Effect of Cholesterol in MCF7 Human Breast Cancer Cells
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Albi E, Mandarano M, Cataldi S, Ceccarini MR, Fiorani F, Beccari T, et al. The Effect of Cholesterol in MCF7 Human Breast Cancer Cells. International Journal of Molecular Sciences. MDPI AG; 2023; 24:5935 10.3390/ijms24065935
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Effects of β-caryophyllene and oxygen availability on cholesterol and fatty acids in breast cancer cells
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Frost CJ, Ramirez-Mata A, Khattri RB, Merritt ME, Frost SC. Effects of β-caryophyllene and oxygen availability on cholesterol and fatty acids in breast cancer cells. PLOS ONE. Public Library of Science (PLoS); 2023; 18:e0281396 10.1371/journal.pone.0281396
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Dyslipidemia is associated with a poor prognosis of breast cancer in patients receiving neoadjuvant chemotherapy
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Ma Y, Lv M, Yuan P, Chen X, Liu Z. Dyslipidemia is associated with a poor prognosis of breast cancer in patients receiving neoadjuvant chemotherapy. BMC Cancer. Springer Science and Business Media LLC; 2023; 23 10.1186/s12885-023-10683-y
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Post-diagnostic statin use and breast cancer-specific mortality: a population-based cohort study
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Scott OW, TinTin S, Harborg S, Kuper-Hommel MJJ, Lawrenson R, Elwood JM. Post-diagnostic statin use and breast cancer-specific mortality: a population-based cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2023; 10.1007/s10549-022-06815-w
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Role of Serum Lipids, Blood Glucose and Blood Pressure in Breast Cancer Risk for Women with Type 2 Diabetes Mellitus
Cite
Zhang F, de Bock GH, Denig P, Landman GW, Zhang Q, Sidorenkov G. Role of Serum Lipids, Blood Glucose and Blood Pressure in Breast Cancer Risk for Women with Type 2 Diabetes Mellitus. Clinical Epidemiology. Informa UK Limited; 2023; Volume 15:109-121 10.2147/clep.s386471
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Association between human blood metabolome and the risk of breast cancer
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Wang Y, Liu F, Sun L, Jia Y, Yang P, Guo D, et al. Association between human blood metabolome and the risk of breast cancer. Breast Cancer Research. Springer Science and Business Media LLC; 2023; 25 10.1186/s13058-023-01609-4
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Metabolic abnormalities and survival among patients with non-metastatic breast cancer
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Zimbalist AS, Caan BJ, Chen WY, Mittendorf EA, Dillon DAR, Quesenberry C, et al. Metabolic abnormalities and survival among patients with non-metastatic breast cancer. BMC Cancer. Springer Science and Business Media LLC; 2022; 22 10.1186/s12885-022-10430-9
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The Link Between Statins and Breast Cancer in Mouse Models: A Systematic Review
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Watson R, Tulk A, Erdrich J. The Link Between Statins and Breast Cancer in Mouse Models: A Systematic Review. Cureus. Cureus, Inc.; 2022; 10.7759/cureus.31893
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Serum cholesterol and the risk of developing hormonally driven cancers: A narrative review
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Murdock DJ, Sanchez RJ, Mohammadi KA, Fazio S, Geba GP. Serum cholesterol and the risk of developing hormonally driven cancers: A narrative review. Cancer Medicine. Wiley; 2022; 10.1002/cam4.5463
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Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion
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Kim HY, Bae SJ, Choi J, Han S, Bae S, Cheong J, et al. Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion. Biomedicines. MDPI AG; 2022; 10:1908 10.3390/biomedicines10081908
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Atorvastatin Improves Cisplatin Sensitivity Through Modulation of Cholesteryl Ester Homeostasis in Breast Cancer Cells
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Santos DZd, Guimaraes IdS, Hakeem-Sanni M, Cochran B, Rye K, Grewal T, et al. Atorvastatin Improves Cisplatin Sensitivity Through Modulation of Cholesteryl Ester Homeostasis in Breast Cancer Cells. Research Square Platform LLC; 2022; 10.21203/rs.3.rs-1907209/v1
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The Role of Cholesterol in the Interaction of the Lipid Monolayer with the Endocrine Disruptor Bisphenol-A
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Katata VM, Maximino MD, Silva CY, Alessio P. The Role of Cholesterol in the Interaction of the Lipid Monolayer with the Endocrine Disruptor Bisphenol-A. Membranes. MDPI AG; 2022; 12:729 10.3390/membranes12080729
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Hypercholesterolemia promotes the intravasation of breast tumor cells through an LDL-LDLR axis
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Dias S, Magalhaes A, Cesário V, Coutinho D, Matias I, Domingues G, et al. Hypercholesterolemia promotes the intravasation of breast tumor cells through an LDL-LDLR axis. Research Square Platform LLC; 2022; 10.21203/rs.3.rs-1760715/v1
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Lipid metabolism in tumor microenvironment: novel therapeutic targets
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Liu X, Zhang P, Xu J, Lv G, Li Y. Lipid metabolism in tumor microenvironment: novel therapeutic targets. Cancer Cell International. Springer Science and Business Media LLC; 2022; 22 10.1186/s12935-022-02645-4
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Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies
Cite
Darooghegi Mofrad M, Naghshi S, Lotfi K, Beyene J, Hypponen E, Pirouzi A, et al. Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies. Frontiers in Nutrition. Frontiers Media SA; 2022; 9 10.3389/fnut.2022.878979
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Availability of bioactive flax lignan from foods and supplements
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Tse TJ, Guo Y, Shim YY, Purdy SK, Kim JH, Cho JY, et al. Availability of bioactive flax lignan from foods and supplements. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2022;:1-16 10.1080/10408398.2022.2072807
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The influence of metabolic factors and ethnicity on breast cancer risk, treatment and survival: The Oslo ethnic breast cancer study
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Lofterød T, Frydenberg H, Veierød MB, Jenum AK, Reitan JB, Wist EA, et al. The influence of metabolic factors and ethnicity on breast cancer risk, treatment and survival: The Oslo ethnic breast cancer study. Acta Oncologica. Informa UK Limited; 2022;:1-9 10.1080/0284186x.2022.2053573
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Abstract P1-15-01: Effect of concomitant statin treatment in postmenopausal patients with hormone-receptor positive early-stage breast cancer receiving adjuvant denosumab or placebo: A post-hoc analysis of ABCSG-18
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Minichsdorfer C, Fuereder T, Leutner M, Singer CF, Kacerovsky-Strobl S, Egle D, et al. Abstract P1-15-01: Effect of concomitant statin treatment in postmenopausal patients with hormone-receptor positive early-stage breast cancer receiving adjuvant denosumab or placebo: A post-hoc analysis of ABCSG-18. Cancer Research. American Association for Cancer Research (AACR); 2022; 82:P1-15-01-P1-15-01 10.1158/1538-7445.sabcs21-p1-15-01
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Metabolic syndrome and breast cancer survivors: a follow-up analysis after completion of chemotherapy
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Dieli-Conwright CM, Wong L, Waliany S, Mortimer JE. Metabolic syndrome and breast cancer survivors: a follow-up analysis after completion of chemotherapy. Diabetology & Metabolic Syndrome. Springer Science and Business Media LLC; 2022; 14 10.1186/s13098-022-00807-y
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Mitochondrial metabolism drives hypercholesterolemia-induced breast cancer cell migration
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Nobrega-Pereira S, Serafim T, Lopes AP, Santos M, Carvalho F, de Jesus BB, et al. Mitochondrial metabolism drives hypercholesterolemia-induced breast cancer cell migration. Research Square Platform LLC; 2022; 10.21203/rs.3.rs-1338648/v1
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Attenuation of obesity-induced hyperlipidemia reduces tumor growth
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Hussain A, Lian J, Watts R, Gutiérrez T, Nelson R, Goping IS, et al. Attenuation of obesity-induced hyperlipidemia reduces tumor growth. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. Elsevier BV; 2022; 1867:159124 10.1016/j.bbalip.2022.159124
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Diet, lipids, and antitumor immunity
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Prendeville H, Lynch L. Diet, lipids, and antitumor immunity. Cellular & Molecular Immunology. Springer Science and Business Media LLC; 2022; 10.1038/s41423-021-00781-x
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Cholesterol Depletion Modulates Drug Resistance Pathways to Sensitize Resistant Breast Cancer Cells to Tamoxifen
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HENRIQUES PALMA GB, KAUR M. Cholesterol Depletion Modulates Drug Resistance Pathways to Sensitize Resistant Breast Cancer Cells to Tamoxifen. Anticancer Research. Anticancer Research USA Inc.; 2021; 42:565-579 10.21873/anticanres.15514
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The effect of tamoxifen on the lipid profile in women: A systematic review and meta-analysis of randomized controlled trials
Cite
Alomar SA, Găman M, Prabahar K, Arafah OA, Almarshood F, Baradwan S, et al. The effect of tamoxifen on the lipid profile in women: A systematic review and meta-analysis of randomized controlled trials. Experimental Gerontology. Elsevier BV; 2022; 159:111680 10.1016/j.exger.2021.111680
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Deep mining and quantification of oxidized cholesteryl esters discovers potential biomarkers involved in breast cancer by liquid chromatography-mass spectrometry
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Wang X, Li H, Zou X, Yan X, Cong P, Li H, et al. Deep mining and quantification of oxidized cholesteryl esters discovers potential biomarkers involved in breast cancer by liquid chromatography-mass spectrometry. Journal of Chromatography A. Elsevier BV; 2022; 1663:462764 10.1016/j.chroma.2021.462764
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Insights into estrogen receptor alpha modulation by cholestenoic acids
Cite
Dansey MV, Palavecino Ruiz MD, Ogara MF, Pecci A, Burton G, Alvarez LD. Insights into estrogen receptor alpha modulation by cholestenoic acids. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2022; 217:106046 10.1016/j.jsbmb.2021.106046
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Association between serum lipids and breast cancer risk in premenopausal women: systematic review and meta-analysis
Cite
Wu J, Lei X, Pan X, Zeng X, Li W. Association between serum lipids and breast cancer risk in premenopausal women: systematic review and meta-analysis. Journal of International Medical Research. SAGE Publications; 2021; 49:030006052110610 10.1177/03000605211061033
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Circulating lipids and breast cancer prognosis in the Malmö diet and cancer study
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Harborg S, Ahern TP, Feldt M, Rosendahl AH, Cronin-Fenton D, Melander O, et al. Circulating lipids and breast cancer prognosis in the Malmö diet and cancer study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-021-06462-7
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Statin use and incidence and mortality of breast and gynecology cancer: A cohort study using the National Health Insurance claims database
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Kim D, Ahn HS, Kim HJ. Statin use and incidence and mortality of breast and gynecology cancer: A cohort study using the National Health Insurance claims database. International Journal of Cancer. Wiley; 2021; 10.1002/ijc.33869
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Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux
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Shapira KE, Shapira G, Schmukler E, Pasmanik-Chor M, Shomron N, Pinkas-Kramarski R, et al. Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux. Cell Death Discovery. Springer Science and Business Media LLC; 2021; 7 10.1038/s41420-021-00718-3
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High density lipoproteins and oxidative stress in breast cancer
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Mazzuferi G, Bacchetti T, Islam MO, Ferretti G. High density lipoproteins and oxidative stress in breast cancer. Lipids in Health and Disease. Springer Science and Business Media LLC; 2021; 20 10.1186/s12944-021-01562-1
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Is it necessary to measure basal serum lipid levels in cancer patients prior to tamoxifen treatment?
Cite
Sütcüoğlu O, Yazıcı O, Özet A. Is it necessary to measure basal serum lipid levels in cancer patients prior to tamoxifen treatment?. Future Oncology. Future Medicine Ltd; 2021; 10.2217/fon-2021-1107
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Investigation of the interplay between circulating lipids and IGF-I and relevance to breast cancer risk: an observational and Mendelian randomization study
Cite
Tan VY, Bull CJ, Biernacka KM, Teumer A, Richardson TG, Sanderson E, et al. Investigation of the interplay between circulating lipids and IGF-I and relevance to breast cancer risk: an observational and Mendelian randomization study. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2021;:cebp.0315.2021 10.1158/1055-9965.epi-21-0315
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Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling
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Scully T, Kase N, Gallagher EJ, LeRoith D. Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling. Scientific Reports. Springer Science and Business Media LLC; 2021; 11 10.1038/s41598-021-97327-y
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Egg Consumption in the Context of Plant-Based Diets and Cardiometabolic Risk Factors in Adults at Risk of Type 2 Diabetes
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Njike VY, Treu JA, Kela GCM, Ayettey RG, Comerford BP, Siddiqui WT. Egg Consumption in the Context of Plant-Based Diets and Cardiometabolic Risk Factors in Adults at Risk of Type 2 Diabetes. The Journal of Nutrition. Oxford University Press (OUP); 2021; 10.1093/jn/nxab283
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Association Between Metabolic Syndrome and Immunohistochemical Profile at Breast Cancer Diagnosis in Postmenopausal Women
Cite
Motoki AH, Buttros DA, Gaspar AL, Almeida-Filho BS, Carvalho-Pessoa E, Vespoli HD, et al. Association Between Metabolic Syndrome and Immunohistochemical Profile at Breast Cancer Diagnosis in Postmenopausal Women. Clinical Breast Cancer. Elsevier BV; 2021; 10.1016/j.clbc.2021.07.009
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Cholesterol lowering drug use and breast cancer survival: the Multiethnic Cohort Study
Cite
Moksud N, Loo LWM, Yang J, Huang C, Haiman CA, Le Marchand L, et al. Cholesterol lowering drug use and breast cancer survival: the Multiethnic Cohort Study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-021-06360-y
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Association of statin use with clinical outcomes in patients with triple‐negative breast cancer
Cite
Nowakowska MK, Lei X, Thompson MT, Shaitelman SF, Wehner MR, Woodward WA, et al. Association of statin use with clinical outcomes in patients with triple‐negative breast cancer. Cancer. Wiley; 2021; 10.1002/cncr.33797
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Biomarkers of mammographic density in premenopausal women
Cite
His M, Lajous M, Gómez-Flores-Ramos L, Monge A, Dossus L, Viallon V, et al. Biomarkers of mammographic density in premenopausal women. Breast Cancer Research. Springer Science and Business Media LLC; 2021; 23 10.1186/s13058-021-01454-3
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Selective estrogen receptor modulators (SERMs) affect cholesterol homeostasis through the master regulators SREBP and LXR
Cite
Fernández-Suárez ME, Daimiel L, Villa-Turégano G, Pavón MV, Busto R, Escolà-Gil JC, et al. Selective estrogen receptor modulators (SERMs) affect cholesterol homeostasis through the master regulators SREBP and LXR. Biomedicine & Pharmacotherapy. Elsevier BV; 2021; 141:111871 10.1016/j.biopha.2021.111871
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Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
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Xu S, Chaudhary O, Rodríguez-Morales P, Sun X, Chen D, Zappasodi R, et al. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors. Immunity. Elsevier BV; 2021; 10.1016/j.immuni.2021.05.003
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The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression
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Baek AE, Krawczynska N, Das Gupta A, Dvoretskiy SV, You S, Park J, et al. The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression. Endocrinology. The Endocrine Society; 2021; 162 10.1210/endocr/bqab095
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Health Benefits Related to Tree Nut Consumption and Their Bioactive Compounds
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Gervasi T, Barreca D, Laganà G, Mandalari G. Health Benefits Related to Tree Nut Consumption and Their Bioactive Compounds. International Journal of Molecular Sciences. MDPI AG; 2021; 22:5960 10.3390/ijms22115960
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Impact of cholesterol-pathways on breast cancer development, a metabolic landscape
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González-Ortiz A, Galindo-Hernández O, Hernández-Acevedo GN, Hurtado-Ureta G, García-González V. Impact of cholesterol-pathways on breast cancer development, a metabolic landscape. Journal of Cancer. Ivyspring International Publisher; 2021; 12:4307-4321 10.7150/jca.54637
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Statin as a Potential Chemotherapeutic Agent: Current Updates as a Monotherapy, Combination Therapy, and Treatment for Anti-Cancer Drug Resistance
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Tilija Pun N, Jeong C. Statin as a Potential Chemotherapeutic Agent: Current Updates as a Monotherapy, Combination Therapy, and Treatment for Anti-Cancer Drug Resistance. Pharmaceuticals. MDPI AG; 2021; 14:470 10.3390/ph14050470
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Identification of a Positive Association between Mammary Adipose Cholesterol Content and Indicators of Breast Cancer Aggressiveness in a French Population
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Goupille C, Ouldamer L, Pinault M, Guimares C, Arbion F, Jourdan ML, et al. Identification of a Positive Association between Mammary Adipose Cholesterol Content and Indicators of Breast Cancer Aggressiveness in a French Population. The Journal of Nutrition. Oxford University Press (OUP); 2021; 10.1093/jn/nxaa432
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Distribution of dyslipidemia in Chinese early breast cancer patients at diagnosis and comparison of dyslipidemia incidence following different endocrine therapies: a population-based cohort study
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Wang J, Yin J, Qiu J, Jiang J, Hu Y, Zheng H, et al. Distribution of dyslipidemia in Chinese early breast cancer patients at diagnosis and comparison of dyslipidemia incidence following different endocrine therapies: a population-based cohort study. Research Square; 2021; 10.21203/rs.3.rs-298866/v1
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Association of Lipid Profile Biomarkers with Breast Cancer by Molecular Subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Women of African Descent (MEND) study
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Akinyemiju T, Gupta A, Saraiya V, Deveaux A, Oyekunle T, Salako O, et al. Association of Lipid Profile Biomarkers with Breast Cancer by Molecular Subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Women of African Descent (MEND) study. Research Square; 2021; 10.21203/rs.3.rs-271970/v1
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Metabolic syndrome risk components and mortality after triple‐negative breast cancer diagnosis in postmenopausal women in the Women's Health Initiative
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Yuan Y, Pan K, Mortimer J, Chlebowski RT, Luo J, Yan JE, et al. Metabolic syndrome risk components and mortality after triple‐negative breast cancer diagnosis in postmenopausal women in the Women's Health Initiative. Cancer. Wiley; 2021; 10.1002/cncr.33407
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Metabolic Syndrome: does this influence breast cancer outcomes in the triple-negative population?
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Kennard K, Buckley ME, Sizer LM, Larson S, Carter WB, Frazier TG, et al. Metabolic Syndrome: does this influence breast cancer outcomes in the triple-negative population?. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-020-06034-1
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The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study
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Johnson KE, Siewert KM, Klarin D, Damrauer SM, Chang K, Tsao PS, et al. The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study. PLOS Medicine. Public Library of Science (PLoS); 2020; 17:e1003302 10.1371/journal.pmed.1003302
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Insulin-Induced Gene 2 Expression Is Associated with Breast Cancer Metastasis
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Lu N, Zhang M, Lu L, Liu Y, Liu X, Zhang H. Insulin-Induced Gene 2 Expression Is Associated with Breast Cancer Metastasis. The American Journal of Pathology. Elsevier BV; 2020; 10.1016/j.ajpath.2020.11.013
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LDL, HDL and endocrine-related cancer: From pathogenic mechanisms to therapies
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Revilla G, Cedó L, Tondo M, Moral A, Pérez JI, Corcoy R, et al. LDL, HDL and endocrine-related cancer: From pathogenic mechanisms to therapies. Seminars in Cancer Biology. Elsevier BV; 2020; 10.1016/j.semcancer.2020.11.012
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CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients
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Kimbung S, Inasu M, Stålhammar T, Nodin B, Elebro K, Tryggvadottir H, et al. CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients. Breast Cancer Research. Springer Science and Business Media LLC; 2020; 22 10.1186/s13058-020-01347-x
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Does adherence to lipid‐lowering medications improve cancer survival? A nationwide study of breast and colorectal cancer, and melanoma
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Feng J, Qin X. Does adherence to lipid‐lowering medications improve cancer survival? A nationwide study of breast and colorectal cancer, and melanoma. British Journal of Clinical Pharmacology. Wiley; 2020; 10.1111/bcp.14573
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Black, pinto and white beans lower hepatic lipids in hamsters fed high fat diets by excretion of bile acids
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Alves PLS, Berrios JDJ, Pan J, Yokoyama WH. Black, pinto and white beans lower hepatic lipids in hamsters fed high fat diets by excretion of bile acids. Food Production, Processing and Nutrition. Springer Science and Business Media LLC; 2020; 2 10.1186/s43014-020-00039-5
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The effect of cranberry consumption on lipid metabolism and inflammation in human apo A-I transgenic mice fed a high-fat and high-cholesterol diet
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Caceres C, Kim M, Bae M, Pham TX, Lee Y, Hu S, et al. The effect of cranberry consumption on lipid metabolism and inflammation in human apo A-I transgenic mice fed a high-fat and high-cholesterol diet. British Journal of Nutrition. Cambridge University Press (CUP); 2020;:1-8 10.1017/s0007114520004080
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Association between statin use and second cancer risk in breast cancer patients: a nationwide population-based cohort study
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Lu Y, Huang D, Chen P, Tsai C, Lin M, Lin C, et al. Association between statin use and second cancer risk in breast cancer patients: a nationwide population-based cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 10.1007/s10549-020-05969-9
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The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study
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Johnson KE, Siewert KM, Klarin D, Damrauer SM, Chang K, Tsao PS, et al. The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study. PLOS Medicine. Public Library of Science (PLoS); 2020; 17:e1003302 10.1371/journal.pmed.1003302
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27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression
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Ma L, Wang L, Nelson AT, Han C, He S, Henn MA, et al. 27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression. Cancer Letters. Elsevier BV; 2020; 493:266-283 10.1016/j.canlet.2020.08.020
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Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells
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Ghanbari F, Mader S, Philip A. Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells. Cells. MDPI AG; 2020; 9:1765 10.3390/cells9081765
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Obesity and related conditions and risk of inflammatory breast cancer: a nested case–control study
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Schairer C, Laurent CA, Moy LM, Gierach GL, Caporaso NE, Pfeiffer RM, et al. Obesity and related conditions and risk of inflammatory breast cancer: a nested case–control study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 183:467-478 10.1007/s10549-020-05785-1
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Statin use and breast cancer recurrence in postmenopausal women treated with adjuvant aromatase inhibitors: a Danish population-based cohort study
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Harborg S, Heide-Jørgensen U, Ahern TP, Ewertz M, Cronin-Fenton D, Borgquist S. Statin use and breast cancer recurrence in postmenopausal women treated with adjuvant aromatase inhibitors: a Danish population-based cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 183:153-160 10.1007/s10549-020-05749-5
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SAT-145 Cholesterol Uptake as a Critical Vulnerability in Triple Negative Breast Cancer
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O’Neill K. SAT-145 Cholesterol Uptake as a Critical Vulnerability in Triple Negative Breast Cancer. Journal of the Endocrine Society. The Endocrine Society; 2020; 4 10.1210/jendso/bvaa046.1368
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Abstract P3-11-17: Statins suppress the aggressive phenotype of triple negative breast cancer cells via modulation of EGFR signalling
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Smith C, Alim S, Kadi A, Lawati RA, Miles M, Hiscox S. Abstract P3-11-17: Statins suppress the aggressive phenotype of triple negative breast cancer cells via modulation of EGFR signalling. Poster Session Abstracts. American Association for Cancer Research; 2020; 10.1158/1538-7445.sabcs19-p3-11-17
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Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study
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Bjarnadottir O, Feldt M, Inasu M, Bendahl P, Elebro K, Kimbung S, et al. Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study. Scientific Reports. Springer Science and Business Media LLC; 2020; 10 10.1038/s41598-019-57323-9
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Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells
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Lupien LE, Bloch K, Dehairs J, Traphagen NA, Feng WW, Davis WL, et al. Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells. Journal of Lipid Research. American Society for Biochemistry & Molecular Biology (ASBMB); 2019; 61:205-218 10.1194/jlr.ra119000327
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Air pollution, noise exposure, and metabolic syndrome – A cohort study in elderly Mexican-Americans in Sacramento area
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Yu Y, Paul K, Arah OA, Mayeda ER, Wu J, Lee E, et al. Air pollution, noise exposure, and metabolic syndrome – A cohort study in elderly Mexican-Americans in Sacramento area. Environment International. Elsevier BV; 2020; 134:105269 10.1016/j.envint.2019.105269
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ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling
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Hutchinson SA, Lianto P, Roberg-Larsen H, Battaglia S, Hughes TA, Thorne JL. ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling. Nutrients. MDPI AG; 2019; 11:2618 10.3390/nu11112618
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Circulating lipids, mammographic density, and risk of breast cancer in the Nurses’ Health Study and Nurses’ Health Study II
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Lucht SA, Eliassen AH, Bertrand KA, Ahern TP, Borgquist S, Rosner B, et al. Circulating lipids, mammographic density, and risk of breast cancer in the Nurses’ Health Study and Nurses’ Health Study II. Cancer Causes & Control. Springer Science and Business Media LLC; 2019; 30:943-953 10.1007/s10552-019-01201-2
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In utero exposure to poly− and perfluoroalkyl substances (PFASs) and subsequent breast cancer
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Cohn BA, La Merrill MA, Krigbaum NY, Wang M, Park J, Petreas M, et al. In utero exposure to poly− and perfluoroalkyl substances (PFASs) and subsequent breast cancer. Reproductive Toxicology. Elsevier BV; 2020; 92:112-119 10.1016/j.reprotox.2019.06.012
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Abstract 1893: Consumption of oil derived from frying bacon increases breast cancer metastasis
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Chen C, Chen JJ, Ma L, Helferich WG, Nelson ER. Abstract 1893: Consumption of oil derived from frying bacon increases breast cancer metastasis. Tumor Biology. American Association for Cancer Research; 2019; 10.1158/1538-7445.am2019-1893
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Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome
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Ehmsen S, Pedersen MH, Wang G, Terp MG, Arslanagic A, Hood BL, et al. Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome. Cell Reports. Elsevier BV; 2019; 27:3927-3938.e6 10.1016/j.celrep.2019.05.104
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Effects of tea consumption and the interactions with lipids on breast cancer survival
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Zhang J, Liao Y, Lin Y, Liu Q, Xie X, Tang L, et al. Effects of tea consumption and the interactions with lipids on breast cancer survival. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2019; 176:679-686 10.1007/s10549-019-05253-5
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Impact of long-term lipid-lowering therapy on clinical outcomes in breast cancer
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Li YR, Ro V, Steel L, Carrigan E, Nguyen J, Williams A, et al. Impact of long-term lipid-lowering therapy on clinical outcomes in breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2019; 176:669-677 10.1007/s10549-019-05267-z
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Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells
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Sharma A, Bandyopadhayaya S, Chowdhury K, Sharma T, Maheshwari R, Das A, et al. Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells. PLOS ONE. Public Library of Science (PLoS); 2019; 14:e0209435 10.1371/journal.pone.0209435
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Statin use and breast cancer survival – a Swedish nationwide study
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Borgquist S, Broberg P, Tojjar J, Olsson H. Statin use and breast cancer survival – a Swedish nationwide study. BMC Cancer. Springer Science and Business Media LLC; 2019; 19 10.1186/s12885-018-5263-z
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Cardioprotective Effect of Statins in Patients With HER2-Positive Breast Cancer Receiving Trastuzumab Therapy
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Calvillo-Argüelles O, Abdel-Qadir H, Michalowska M, Billia F, Suntheralingam S, Amir E, et al. Cardioprotective Effect of Statins in Patients With HER2-Positive Breast Cancer Receiving Trastuzumab Therapy. Canadian Journal of Cardiology. Elsevier BV; 2018; 35:153-159 10.1016/j.cjca.2018.11.028
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Statin use and risk of contralateral breast cancer: a nationwide cohort study
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Langballe R, Cronin-Fenton D, Dehlendorff C, Jensen M, Ejlertsen B, Andersson M, et al. Statin use and risk of contralateral breast cancer: a nationwide cohort study. British Journal of Cancer. Springer Science and Business Media LLC; 2018; 119:1297-1305 10.1038/s41416-018-0252-1
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Therapeutic effect of simvastatin on DMBA-induced breast cancer in mice
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Karimi B, Ashrafi M, Shomali T, Yektaseresht A. Therapeutic effect of simvastatin on DMBA-induced breast cancer in mice. Fundamental & Clinical Pharmacology. Wiley; 2018; 33:84-93 10.1111/fcp.12397
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Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes
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Lofterød T, Mortensen ES, Nalwoga H, Wilsgaard T, Frydenberg H, Risberg T, et al. Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4568-2
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Lipid-lowering drugs, dyslipidemia, and breast cancer risk in a Medicare population
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Schairer C, Freedman DM, Gadalla SM, Pfeiffer RM. Lipid-lowering drugs, dyslipidemia, and breast cancer risk in a Medicare population. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2018; 169:607-614 10.1007/s10549-018-4680-7
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Metabolic Obesity Phenotypes and Risk of Breast Cancer in Postmenopausal Women
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Kabat GC, Kim MY, Lee JS, Ho GY, Going SB, Beebe-Dimmer J, et al. Metabolic Obesity Phenotypes and Risk of Breast Cancer in Postmenopausal Women. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2017; 26:1730-1735 10.1158/1055-9965.epi-17-0495
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Dietary Factors and Female Breast Cancer Risk: A Prospective Cohort Study
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Kim J, Lee J, Jung S, Kim J. Dietary Factors and Female Breast Cancer Risk: A Prospective Cohort Study. Nutrients. MDPI AG; 2017; 9:1331 10.3390/nu9121331
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Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial
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Going CC, Alexandrova L, Lau K, Yeh CY, Feldman D, Pitteri SJ. Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 167:797-802 10.1007/s10549-017-4562-4
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The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells
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Baek AE, Yu YA, He S, Wardell SE, Chang C, Kwon S, et al. The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells. Nature Communications. Springer Science and Business Media LLC; 2017; 8 10.1038/s41467-017-00910-z
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Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines
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Karlic H, Haider F, Thaler R, Spitzer S, Klaushofer K, Varga F. Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines. International Journal of Molecular Sciences. MDPI AG; 2017; 18:1982 10.3390/ijms18091982
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The impact of cranberry (Vaccinium macrocarpon) and cranberry products on each component of the metabolic syndrome: a review
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Thimóteo NSB, Scavuzzi BM, Simão ANC, Dichi I. The impact of cranberry (Vaccinium macrocarpon) and cranberry products on each component of the metabolic syndrome: a review. Nutrire. Springer Science and Business Media LLC; 2017; 42 10.1186/s41110-017-0048-8
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Metabolic conditions and breast cancer risk among Los Angeles County Filipina Americans compared with Chinese and Japanese Americans
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Wu AH, Vigen C, Butler LM, Tseng C. Metabolic conditions and breast cancer risk among Los Angeles County Filipina Americans compared with Chinese and Japanese Americans. International Journal of Cancer. Wiley; 2017; 141:2450-2461 10.1002/ijc.31018
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Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy
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Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia
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Gallagher EJ, Zelenko Z, Neel BA, Antoniou IM, Rajan L, Kase N, et al. Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia. Oncogene. Springer Science and Business Media LLC; 2017; 36:6462-6471 10.1038/onc.2017.247
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Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death
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Leignadier J, Dalenc F, Poirot M, Silvente-Poirot S. Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death. Biochemical Pharmacology. Elsevier BV; 2017; 144:18-28 10.1016/j.bcp.2017.06.120
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Different patterns in the risk of newly developed fatty liver and lipid changes with tamoxifen versus aromatase inhibitors in postmenopausal women with early breast cancer: A propensity score–matched cohort study
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Hong N, Yoon HG, Seo DH, Park S, Kim SI, Sohn JH, et al. Different patterns in the risk of newly developed fatty liver and lipid changes with tamoxifen versus aromatase inhibitors in postmenopausal women with early breast cancer: A propensity score–matched cohort study. European Journal of Cancer. Elsevier BV; 2017; 82:103-114 10.1016/j.ejca.2017.05.002
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The relationship between statins and breast cancer prognosis varies by statin type and exposure time: a meta-analysis
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Liu B, Yi Z, Guan X, Zeng Y, Ma F. The relationship between statins and breast cancer prognosis varies by statin type and exposure time: a meta-analysis. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 164:1-11 10.1007/s10549-017-4246-0
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Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer
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Metabolic factors, anthropometric measures, diet, and physical activity in long-term breast cancer survivors: change from diagnosis and comparison to non-breast cancer controls
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Lohmann AE, Ennis M, Taylor SK, Goodwin PJ. Metabolic factors, anthropometric measures, diet, and physical activity in long-term breast cancer survivors: change from diagnosis and comparison to non-breast cancer controls. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 164:451-460 10.1007/s10549-017-4263-z
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Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study
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Borgquist S, Giobbie-Hurder A, Ahern TP, Garber JE, Colleoni M, Láng I, et al. Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2017; 35:1179-1188 10.1200/jco.2016.70.3116
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Glucose and lipoprotein biomarkers and breast cancer severity using data from the Swedish AMORIS cohort
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27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3
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Shen Z, Zhu D, Liu J, Chen J, Liu Y, Hu C, et al. 27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3. Environmental Toxicology and Pharmacology. Elsevier BV; 2017; 51:1-8 10.1016/j.etap.2017.02.001
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Antihyperglycemic Effect of Quercetin in Ovariectomized Rats Treated with Tamoxifen
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Silva FC, Bramatti IC, Toledo AG, Salles FM, Itinose AM, Marek CB. Antihyperglycemic Effect of Quercetin in Ovariectomized Rats Treated with Tamoxifen. Journal of Medicinal Food. Mary Ann Liebert Inc; 2017; 20:235-242 10.1089/jmf.2016.0078
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Diabetes, Abnormal Glucose, Dyslipidemia, Hypertension, and Risk of Inflammatory and Other Breast Cancer
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Schairer C, Gadalla SM, Pfeiffer RM, Moore SC, Engels EA. Diabetes, Abnormal Glucose, Dyslipidemia, Hypertension, and Risk of Inflammatory and Other Breast Cancer. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2017; 26:862-868 10.1158/1055-9965.epi-16-0647
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VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis
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Lu C, Lo Y, Chen C, Lin C, Tsai C, Chen P, et al. VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis. Cancer Letters. Elsevier BV; 2017; 388:130-138 10.1016/j.canlet.2016.11.033
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Membrane cholesterol depletion reduces breast tumor cell migration by a mechanism that involves non-canonical Wnt signaling and IL-10 secretion
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Guerra FS, Sampaio LdS, Konig S, Bonamino M, Rossi MID, Costa ML, et al. Membrane cholesterol depletion reduces breast tumor cell migration by a mechanism that involves non-canonical Wnt signaling and IL-10 secretion. Translational Medicine Communications. Springer Science and Business Media LLC; 2016; 1 10.1186/s41231-016-0002-4
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De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I–III breast cancer
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Smith A, Murphy L, Sharp L, O'Connor D, Gallagher WM, Bennett K, et al. De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I–III breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2016; 115:592-598 10.1038/bjc.2016.232
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Statin use and all-cancer survival: prospective results from the Women’s Health Initiative
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Wang A, Aragaki AK, Tang JY, Kurian AW, Manson JE, Chlebowski RT, et al. Statin use and all-cancer survival: prospective results from the Women’s Health Initiative. British Journal of Cancer. Springer Science and Business Media LLC; 2016; 115:129-135 10.1038/bjc.2016.149
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Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
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Simigdala N, Gao Q, Pancholi S, Roberg-Larsen H, Zvelebil M, Ribas R, et al. Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer. Breast Cancer Research. Springer Science and Business Media LLC; 2016; 18 10.1186/s13058-016-0713-5
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Impact of statin use on cancer recurrence and mortality in breast cancer: A systematic review and meta-analysis
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Manthravadi S, Shrestha A, Madhusudhana S. Impact of statin use on cancer recurrence and mortality in breast cancer: A systematic review and meta-analysis. International Journal of Cancer. Wiley; 2016; 139:1281-1288 10.1002/ijc.30185
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Systematic review and meta-analysis suggest that dietary cholesterol intake increases risk of breast cancer
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Li C, Yang L, Zhang D, Jiang W. Systematic review and meta-analysis suggest that dietary cholesterol intake increases risk of breast cancer. Nutrition Research. Elsevier BV; 2016; 36:627-635 10.1016/j.nutres.2016.04.009
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Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer
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Flote VG, Vettukattil R, Bathen TF, Egeland T, McTiernan A, Frydenberg H, et al. Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer. Lipids in Health and Disease. Springer Science and Business Media LLC; 2016; 15 10.1186/s12944-016-0225-4
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High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation
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Huang X, He D, Ming J, He Y, Zhou C, Ren H, et al. High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 155:441-455 10.1007/s10549-016-3696-0
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Associations between Metabolic Syndrome and Three-dimensional Breast Density Using Digital Mammography
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Bhang S, Lee H, Kang J, Yu B. Associations between Metabolic Syndrome and Three-dimensional Breast Density Using Digital Mammography. Korean Journal of Health Promotion. Korean Society of Health Promotion and Disease Prevention (KAMJE); 2015; 15:168 10.15384/kjhp.2015.15.4.168
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Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells
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Sharma M, Tuaine J, McLaren B, Waters DL, Black K, Jones LM, et al. Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells. PLOS ONE. Public Library of Science (PLoS); 2016; 11:e0148049 10.1371/journal.pone.0148049
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Evidence of pomegranate methanolic extract in antagonizing the endogenous SERM, 27-hydroxycholesterol
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Vini R, Juberiya AM, Sreeja S. Evidence of pomegranate methanolic extract in antagonizing the endogenous SERM, 27-hydroxycholesterol. IUBMB Life. Wiley; 2016; 68:116-121 10.1002/iub.1465
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Statin Use and Breast Cancer Risk in the Nurses' Health Study
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Borgquist S, Tamimi RM, Chen WY, Garber JE, Eliassen AH, Ahern TP. Statin Use and Breast Cancer Risk in the Nurses' Health Study. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2016; 25:201-206 10.1158/1055-9965.epi-15-0654
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Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer
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Iyengar NM, Zhou XK, Gucalp A, Morris PG, Howe LR, Giri DD, et al. Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer. Clinical Cancer Research. American Association for Cancer Research (AACR); 2015; 22:2283-2289 10.1158/1078-0432.ccr-15-2239
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Could Low Hdl-Cholesterol Levels Be an Unvalued Predictor of Cancer Risk?: A Retrospective Case Study
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Vílchez JA, Sancho-Rodríguez N, Martínez-Ruiz A, Martínez-Sánchez E, Ruiz-Espejo F, Tovar-Zapata I, et al. Could Low Hdl-Cholesterol Levels Be an Unvalued Predictor of Cancer Risk?: A Retrospective Case Study. International Journal of Clinical Medicine. Scientific Research Publishing, Inc.; 2015; 06:984-992 10.4236/ijcm.2015.612129
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Associations between Medical Conditions and Breast Cancer Risk in Asians: A Nationwide Population-Based Study in Taiwan
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Chuang S, Wu G, Lu Y, Lin C, Hsiung CA. Associations between Medical Conditions and Breast Cancer Risk in Asians: A Nationwide Population-Based Study in Taiwan. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0143410 10.1371/journal.pone.0143410
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Prediagnostic serum glucose and lipids in relation to survival in breast cancer patients: a competing risk analysis
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Wulaningsih W, Vahdaninia M, Rowley M, Holmberg L, Garmo H, Malmstrom H, et al. Prediagnostic serum glucose and lipids in relation to survival in breast cancer patients: a competing risk analysis. BMC Cancer. Springer Science and Business Media LLC; 2015; 15 10.1186/s12885-015-1928-z
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Serum Lipids and Breast Cancer Risk: A Meta-Analysis of Prospective Cohort Studies
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Ni H, Liu H, Gao R. Serum Lipids and Breast Cancer Risk: A Meta-Analysis of Prospective Cohort Studies. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0142669 10.1371/journal.pone.0142669
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Abstract A82: The cholesterol metabolite, 27-hydroxycholesterol, promotes breast cancer metastasis
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Nelson ER, Wardell SE, McDonnell DP. Abstract A82: The cholesterol metabolite, 27-hydroxycholesterol, promotes breast cancer metastasis. Tumor Microenvironment. American Association for Cancer Research; 2015; 10.1158/2326-6074.tumimm14-a82
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Metabolic and anthropometric changes in early breast cancer patients receiving adjuvant therapy
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Arpino G, De Angelis C, Buono G, Colao A, Giuliano M, Malgieri S, et al. Metabolic and anthropometric changes in early breast cancer patients receiving adjuvant therapy. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2015; 154:127-132 10.1007/s10549-015-3586-x
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Cholesterol and breast cancer risk: a systematic review and meta-analysis of prospective studies
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Touvier M, Fassier P, His M, Norat T, Chan DSM, Blacher J, et al. Cholesterol and breast cancer risk: a systematic review and meta-analysis of prospective studies. British Journal of Nutrition. Cambridge University Press (CUP); 2015; 114:347-357 10.1017/s000711451500183x
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Serum Lipids, Lipoproteins, and Risk of Breast Cancer: A Nested Case-Control Study Using Multiple Time Points
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Martin LJ, Melnichouk O, Huszti E, Connelly PW, Greenberg CV, Minkin S, et al. Serum Lipids, Lipoproteins, and Risk of Breast Cancer: A Nested Case-Control Study Using Multiple Time Points. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2015; 107:djv032-djv032 10.1093/jnci/djv032
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Tamoxifen Treatment and the Reduced Risk of Hyperlipidemia in Asian Patients With Breast Cancer: A Population-Based Cohort Study
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Lim Y, Lin C, Lin Y, Ma W, Hung D, Kao C. Tamoxifen Treatment and the Reduced Risk of Hyperlipidemia in Asian Patients With Breast Cancer: A Population-Based Cohort Study. Clinical Breast Cancer. Elsevier BV; 2015; 15:294-300 10.1016/j.clbc.2015.03.005
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High-Density and Very-Low-Density Lipoprotein Have Opposing Roles in Regulating Tumor-Initiating Cells and Sensitivity to Radiation in Inflammatory Breast Cancer
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Wolfe AR, Atkinson RL, Reddy JP, Debeb BG, Larson R, Li L, et al. High-Density and Very-Low-Density Lipoprotein Have Opposing Roles in Regulating Tumor-Initiating Cells and Sensitivity to Radiation in Inflammatory Breast Cancer. International Journal of Radiation Oncology*Biology*Physics. Elsevier BV; 2015; 91:1072-1080 10.1016/j.ijrobp.2014.12.039
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Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism
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Shim JS, Li R, Lv J, Head SA, Yang EJ, Liu JO. Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism. Cancer Letters. Elsevier BV; 2015; 362:106-115 10.1016/j.canlet.2015.03.022
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Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis
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McDonnell DP, Park S, Goulet MT, Jasper J, Wardell SE, Chang C, et al. Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis. Cancer Research. American Association for Cancer Research (AACR); 2014; 74:4976-4982 10.1158/0008-5472.can-14-1756
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Metabolic syndrome and breast cancer prognosis
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Berrino F, Villarini A, Traina A, Bonanni B, Panico S, Mano MP, et al. Metabolic syndrome and breast cancer prognosis. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2014; 147:159-165 10.1007/s10549-014-3076-6
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Hypercholesterolemia Induces Angiogenesis and Accelerates Growth of Breast Tumors in Vivo
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Pelton K, Coticchia CM, Curatolo AS, Schaffner CP, Zurakowski D, Solomon KR, et al. Hypercholesterolemia Induces Angiogenesis and Accelerates Growth of Breast Tumors in Vivo. The American Journal of Pathology. Elsevier BV; 2014; 184:2099-2110 10.1016/j.ajpath.2014.03.006
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Premenopausal dietary fat in relation to pre- and post-menopausal breast cancer
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Farvid MS, Cho E, Chen WY, Eliassen AH, Willett WC. Premenopausal dietary fat in relation to pre- and post-menopausal breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2014; 145:255-265 10.1007/s10549-014-2895-9
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Adjuvant Tamoxifen Influences the Lipid Profile in Breast Cancer Patients
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Lin C, Chen L, Kuo S, Chen D. Adjuvant Tamoxifen Influences the Lipid Profile in Breast Cancer Patients. Breast Care. S. Karger AG; 2014; 9:1-1 10.1159/000358752
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LDL-cholesterol signaling induces breast cancer proliferation and invasion
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Rodrigues dos Santos C, Domingues G, Matias I, Matos J, Fonseca I, de Almeida J, et al. LDL-cholesterol signaling induces breast cancer proliferation and invasion. Lipids in Health and Disease. Springer Science and Business Media LLC; 2014; 13:16 10.1186/1476-511x-13-16
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27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth
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Wu Q, Ishikawa T, Sirianni R, Tang H, McDonald J, Yuhanna I, et al. 27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth. Cell Reports. Elsevier BV; 2013; 5:637-645 10.1016/j.celrep.2013.10.006
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Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women
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Botteri E, Munzone E, Rotmensz N, Cipolla C, De Giorgi V, Santillo B, et al. Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 140:567-575 10.1007/s10549-013-2654-3
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The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA.17L)
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Wasan K, Goss P, Pritchard P, Shepherd L, Palmer M, Liu S, et al. The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA.17L). Annals of Oncology. Elsevier BV; 2005; 16:707-715 10.1093/annonc/mdi158
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Lipid concentrations in postmenopausal women on letrozole after 5 years of tamoxifen: an NCIC CTG MA.17 sub-study
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Wasan KM, Goss PE, Pritchard PH, Shepherd L, Tu D, Ingle JN. Lipid concentrations in postmenopausal women on letrozole after 5 years of tamoxifen: an NCIC CTG MA.17 sub-study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 136:769-776 10.1007/s10549-012-2294-z
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Chemical–Physical Changes in Cell Membrane Microdomains of Breast Cancer Cells After Omega-3 PUFA Incorporation
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Corsetto PA, Cremona A, Montorfano G, Jovenitti IE, Orsini F, Arosio P, et al. Chemical–Physical Changes in Cell Membrane Microdomains of Breast Cancer Cells After Omega-3 PUFA Incorporation. Cell Biochemistry and Biophysics. Springer Science and Business Media LLC; 2012; 64:45-59 10.1007/s12013-012-9365-y
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Total Serum Cholesterol and Cancer Incidence in the Metabolic Syndrome and Cancer Project (Me-Can)
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Strohmaier S, Edlinger M, Manjer J, Stocks T, Bjørge T, Borena W, et al. Total Serum Cholesterol and Cancer Incidence in the Metabolic Syndrome and Cancer Project (Me-Can). PLoS ONE. Public Library of Science (PLoS); 2013; 8:e54242 10.1371/journal.pone.0054242
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The statin-low cholesterol-cancer conundrum
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Ravnskov U, McCully KS, Rosch PJ. The statin-low cholesterol-cancer conundrum. QJM. Oxford University Press (OUP); 2011; 105:383-388 10.1093/qjmed/hcr243
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Chemical–Physical Changes in Cell Membrane Microdomains of Breast Cancer Cells After Omega-3 PUFA Incorporation
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Corsetto PA, Cremona A, Montorfano G, Jovenitti IE, Orsini F, Arosio P, et al. Chemical–Physical Changes in Cell Membrane Microdomains of Breast Cancer Cells After Omega-3 PUFA Incorporation. Cell Biochemistry and Biophysics. Springer Science and Business Media LLC; 2012; 64:45-59 10.1007/s12013-012-9365-y
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Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden
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Attner B, Landin-Olsson M, Lithman T, Noreen D, Olsson H. Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden. Cancer Causes & Control. Springer Science and Business Media LLC; 2012; 23:769-777 10.1007/s10552-012-9946-5
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Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification
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Antalis CJ, Uchida A, Buhman KK, Siddiqui RA. Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification. Clinical & Experimental Metastasis. Springer Science and Business Media LLC; 2011; 28:733-741 10.1007/s10585-011-9405-9
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Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
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Freed-Pastor W, Mizuno H, Zhao X, Langerød A, Moon S, Rodriguez-Barrueco R, et al. Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway. Cell. Elsevier BV; 2012; 148:244-258 10.1016/j.cell.2011.12.017
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Role of Cholesterol in the Development and Progression of Breast Cancer
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Llaverias G, Danilo C, Mercier I, Daumer K, Capozza F, Williams TM, et al. Role of Cholesterol in the Development and Progression of Breast Cancer. The American Journal of Pathology. Elsevier BV; 2011; 178:402-412 10.1016/j.ajpath.2010.11.005
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Metabolic Syndrome and Breast Cancer in the Me-Can (Metabolic Syndrome and Cancer) Project
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Bjørge T, Lukanova A, Jonsson H, Tretli S, Ulmer H, Manjer J, et al. Metabolic Syndrome and Breast Cancer in the Me-Can (Metabolic Syndrome and Cancer) Project. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2010; 19:1737-1745 10.1158/1055-9965.epi-10-0230
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The association of metabolic syndrome with triple-negative breast cancer
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Maiti B, Kundranda MN, Spiro TP, Daw HA. The association of metabolic syndrome with triple-negative breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2009; 121:479-483 10.1007/s10549-009-0591-y
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Health effect of vegetable-based diet: lettuce consumption improves cholesterol metabolism and antioxidant status in the rat
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Nicolle C, Cardinault N, Gueux E, Jaffrelo L, Rock E, Mazur A, et al. Health effect of vegetable-based diet: lettuce consumption improves cholesterol metabolism and antioxidant status in the rat. Clinical Nutrition. Elsevier BV; 2004; 23:605-614 10.1016/j.clnu.2003.10.009
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Lipid-lowering action of pectin from Cucumis sativus
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Sudheesh S, Vijayalakshmi N. Lipid-lowering action of pectin from Cucumis sativus. Food Chemistry. Elsevier BV; 1999; 67:281-286 10.1016/s0308-8146(99)00135-1
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Antidiabetic Activity of Mung Bean Extracts in Diabetic KK-AyMice
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Yao Y, Chen F, Wang M, Wang J, Ren G. Antidiabetic Activity of Mung Bean Extracts in Diabetic KK-AyMice. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2008; 56:8869-8873 10.1021/jf8009238
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Effects of kiwifruit consumption on serum lipid profiles and antioxidative status in hyperlipidemic subjects
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Chang W, Liu J. Effects of kiwifruit consumption on serum lipid profiles and antioxidative status in hyperlipidemic subjects. International Journal of Food Sciences and Nutrition. Informa UK Limited; 2009; 60:709-716 10.3109/09637480802063517
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Steam cooking significantly improves in vitro bile acid binding of beets, eggplant, asparagus, carrots, green beans, and cauliflower
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Kahlon TS, Chiu MM, Chapman MH. Steam cooking significantly improves in vitro bile acid binding of beets, eggplant, asparagus, carrots, green beans, and cauliflower. Nutrition Research. Elsevier BV; 2007; 27:750-755 10.1016/j.nutres.2007.09.011
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3-(4′-Hydroxyl-3′,5′-dimethoxyphenyl)propionic Acid, an Active Principle of Kimchi, Inhibits Development of Atherosclerosis in Rabbits
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Kim HJ, Lee JS, Chung HY, Song SH, Suh H, Noh JS, et al. 3-(4′-Hydroxyl-3′,5′-dimethoxyphenyl)propionic Acid, an Active Principle of Kimchi, Inhibits Development of Atherosclerosis in Rabbits. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2007; 55:10486-10492 10.1021/jf072454m