Tag: carvacrol
Carvacrol: A phenolic monoterpene found in herbs such as black cumin, Mexican oregano, and oregano.
Foods
Studies
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Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells
Cite
Mari A, Mani G, Nagabhishek SN, Balaraman G, Subramanian N, Mirza FB, et al. Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells. Chinese Journal of Integrative Medicine. Springer Science and Business Media LLC; 2020; 27:680-687 10.1007/s11655-020-3193-5
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Metabolic and Cytotoxic Effects of Mexican oregano (Lippia graveolens Kunth) Infusion and Carvacrol on Breast Cancer Cell Lines
Cite
Rojo-Ruvalcaba BE, Maldonado-González M, Cálix-Rodríguez G, Valdés-Miramontes E, Gómez-Leyva J, García-Cobián T, et al. Metabolic and Cytotoxic Effects of Mexican oregano (Lippia graveolens Kunth) Infusion and Carvacrol on Breast Cancer Cell Lines. MDPI AG; 2025; 10.20944/preprints202505.1378.v1
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An updated review on the phytochemistry and pharmacological activity of black cumin (Nigella sativa L.)
Cite
Pandey R, Pandey B, Bhargava A. An updated review on the phytochemistry and pharmacological activity of black cumin (Nigella sativa L.). Advanced Chinese Medicine. Wiley; 2025; 10.1002/acm4.33
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In vitro evaluation of Hyphaene thebaica honey as a multitarget therapeutic product
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Abu-Farich B, Masalha M, Hamarshi H, El Ghouizi A, Aboulghazi A, El Ouassete M, et al. In vitro evaluation of Hyphaene thebaica honey as a multitarget therapeutic product. Microbes; Immunity. AccScience Publishing; 2025; 2:78 10.36922/mi.4994
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Nigella sativa (Black Seed) and Breast Cancer: A Systematic Review
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Esmaeli M, Ghanbari A, Barazesh M, Dehabadi MD. Nigella sativa (Black Seed) and Breast Cancer: A Systematic Review. Indian Journal of Gynecologic Oncology. Springer Science and Business Media LLC; 2024; 22 10.1007/s40944-024-00920-y
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Nano-enabled thermo-responsive local delivery of tamoxifen and carvacrol for enhanced anticancer action
Cite
Walke N, Aalhate M, Mahajan S, Singh H, Maji I, Gupta U, et al. Nano-enabled thermo-responsive local delivery of tamoxifen and carvacrol for enhanced anticancer action. Journal of Drug Delivery Science and Technology. Elsevier BV; 2024; 100:106013 10.1016/j.jddst.2024.106013
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Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines
Cite
Taibi M, Elbouzidi A, Haddou M, Baraich A, Ou-Yahia D, Bellaouchi R, et al. Evaluation of the Interaction between Carvacrol and Thymol, Major Compounds of Ptychotis verticillata Essential Oil: Antioxidant, Anti-Inflammatory and Anticancer Activities against Breast Cancer Lines. Life. MDPI AG; 2024; 14:1037 10.3390/life14081037
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Nano-enabled thermo-responsive local delivery of tamoxifen and carvacrol for enhanced anticancer action
Cite
Walke N, Aalhate M, Mahajan S, Singh H, Maji I, Gupta U, et al. Nano-enabled thermo-responsive local delivery of tamoxifen and carvacrol for enhanced anticancer action. Journal of Drug Delivery Science and Technology. Elsevier BV; 2024; 100:106013 10.1016/j.jddst.2024.106013
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Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway
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Chen H, Zhou J, Fong SY. Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway. Pakistan Journal of Zoology. ResearchersLinks Ltd; 2024; 56 10.17582/journal.pjz/20220421100442
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Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways
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Singh J, Luqman S, Meena A. Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways. Current Molecular Pharmacology. Elsevier BV; 2023; 16 10.2174/1874467215666220705142954
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Exploring the anti-cancer properties of essential oils from some Lamiaceae species against human cancer cells with multivariate analysis
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Gezici S, Turkmen M, Karahan F. Exploring the anti-cancer properties of essential oils from some Lamiaceae species against human cancer cells with multivariate analysis. South African Journal of Botany. Elsevier BV; 2024; 166:287-296 10.1016/j.sajb.2023.10.057
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Synthesis and biological evaluation of several new heterocyclic carvacrol esters
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Bsharat I, Abdalla L, Sawafta A, Abu-Reidah IM, Al-Nuri MA. Synthesis and biological evaluation of several new heterocyclic carvacrol esters. Journal of Molecular Structure. Elsevier BV; 2024; 1295:136599 10.1016/j.molstruc.2023.136599
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Impact of fractional distillation on physicochemical and biological properties of oregano essential oil of Lippia graveolens H.B.K. grown wild in Mexico
Cite
Castillo Herrera GA, Espinosa ME, Haro González JN, García Fajardo JA, Andrews HE, Velázquez MM. Impact of fractional distillation on physicochemical and biological properties of oregano essential oil of Lippia graveolens H.B.K. grown wild in Mexico. Journal of Essential Oil Bearing Plants. Informa UK Limited; 2023; 26:1515-1525 10.1080/0972060x.2023.2295418
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Carvacrol-Fabricated Chitosan Nanoparticle Synergistic Potential with Topoisomerase Inhibitors on Breast and Cervical Cancer Cells
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Akhlaq A, Ashraf M, Omer MO, Altaf I. Carvacrol-Fabricated Chitosan Nanoparticle Synergistic Potential with Topoisomerase Inhibitors on Breast and Cervical Cancer Cells. ACS Omega. American Chemical Society (ACS); 2023; 10.1021/acsomega.3c03337
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Exploring the Potent Anticancer Activity of Essential Oils and Their Bioactive Compounds: Mechanisms and Prospects for Future Cancer Therapy
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Mohamed Abdoul-Latif F, Ainane A, Houmed Aboubaker I, Mohamed J, Ainane T. Exploring the Potent Anticancer Activity of Essential Oils and Their Bioactive Compounds: Mechanisms and Prospects for Future Cancer Therapy. Pharmaceuticals. MDPI AG; 2023; 16:1086 10.3390/ph16081086
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A mechanistic insight into the potential anti-cancerous property of Nigella sativa on breast cancer through micro-RNA regulation: An in vitro & in vivo study
Cite
Das S, Ghosh A, Upadhyay P, Sarker S, Bhattacharjee M, Gupta P, et al. A mechanistic insight into the potential anti-cancerous property of Nigella sativa on breast cancer through micro-RNA regulation: An in vitro & in vivo study. Fitoterapia. Elsevier BV; 2023;:105601 10.1016/j.fitote.2023.105601
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Dietary flavonoid carvacrol triggers the apoptosis of human breast cancer MCF-7 cells via the p53/Bax/Bcl-2 axis
Cite
Moradipour A, Dariushnejad H, Ahmadizadeh C, Lashgarian HE. Dietary flavonoid carvacrol triggers the apoptosis of human breast cancer MCF-7 cells via the p53/Bax/Bcl-2 axis. Medical Oncology. Springer Science and Business Media LLC; 2022; 40 10.1007/s12032-022-01918-2
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A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update
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Machado TQ, da Fonseca ACC, Duarte ABS, Robbs BK, de Sousa DP. A Narrative Review of the Antitumor Activity of Monoterpenes from Essential Oils: An Update. BioMed Research International. Hindawi Limited; 2022; 2022:1-20 10.1155/2022/6317201
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Carvacrol Enhance Apoptotic Effect of 5-FU on MCF-7 Cell Line via inhibiting P-glycoprotein: An In-silco and In-vitro Study
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Ghorbanzadeh V, Aljaf KAH, Wasman HM, Pirzeh L, Azimi S, Dariushnejad H. Carvacrol Enhance Apoptotic Effect of 5-FU on MCF-7 Cell Line via inhibiting P-glycoprotein: An In-silco and In-vitro Study. Drug Research. Georg Thieme Verlag KG; 2022; 10.1055/a-1766-5491
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Therapeutic Potential of Certain Terpenoids as Anticancer Agents: A Scoping Review
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Kamran S, Sinniah A, Abdulghani MAM, Alshawsh MA. Therapeutic Potential of Certain Terpenoids as Anticancer Agents: A Scoping Review. Cancers. MDPI AG; 2022; 14:1100 10.3390/cancers14051100
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Carvacrol Promotes Cisplatin-induced Apoptosis of Triple-negative Breast Cancer Through TRPM7 Channels
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Li J, Ye H, Wang J, Qin J, Chen L. Carvacrol Promotes Cisplatin-induced Apoptosis of Triple-negative Breast Cancer Through TRPM7 Channels. Research Square; 2021; 10.21203/rs.3.rs-291089/v1
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Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB 231
Cite
Arunasree K. Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB 231. Phytomedicine. Elsevier BV; 2010; 17:581-588 10.1016/j.phymed.2009.12.008