Tag: CLA

CLA (conjugated linoleic acid): A mixture of isomers of the omega-6 fatty acid linoleic acid. Found naturally primarily in dairy foods and meat derived from ruminants such as cattle.

Articles

News

03/09/20: Milk is linked to increased breast cancer risk
03/18/13: Full fat dairy linked to increased risk of breast cancer recurrence
10/25/11: Milk increases proliferation of estrogen-sensitive BC cells
01/20/10: Conjugated linoleic acid (CLA) inhibits the growth of BC cells

Foods

- beef
- butter
- cheese
- milk
- yogurt

Studies

Gut microbial fatty acid isomerization modulates intraepithelial T cells Cite
Song X, Zhang H, Zhang Y, Goh B, Bao B, Mello SS, et al. Gut microbial fatty acid isomerization modulates intraepithelial T cells. Nature. Springer Science and Business Media LLC; 2023; 10.1038/s41586-023-06265-4
Abstract P3-12-35: Industrial and ruminant trans fatty acid intakes and cancer risk: Results from the NutriNet-Santé cohort Cite
Wendeu-Foyet G, Chajes V, Huybrechts I, Bard J, Debras C, Chazelas E, et al. Abstract P3-12-35: Industrial and ruminant trans fatty acid intakes and cancer risk: Results from the NutriNet-Santé cohort. Cancer Research. American Association for Cancer Research (AACR); 2022; 82:P3-12-35-P3-12-35 10.1158/1538-7445.sabcs21-p3-12-35
Dietary trans fatty acid intakes and cancer risk: results from the NutriNet-Santé cohort Cite
Wendeu-Foyet G, Chajes V, Huybrechts I, Debras C, Chazelas E, Srour B, et al. Dietary trans fatty acid intakes and cancer risk: results from the NutriNet-Santé cohort. European Journal of Public Health. Oxford University Press (OUP); 2021; 31 10.1093/eurpub/ckab164.415
The Effect of Trans Fatty Acids on Human Health: Regulation and Consumption Patterns Cite
Pipoyan D, Stepanyan S, Stepanyan S, Beglaryan M, Costantini L, Molinari R, et al. The Effect of Trans Fatty Acids on Human Health: Regulation and Consumption Patterns. Foods. MDPI AG; 2021; 10:2452 10.3390/foods10102452
In Utero Exposure to trans-10, cis-12 Conjugated Linoleic Acid Modifies Postnatal Development of the Mammary Gland and its Hormone Responsiveness Cite
Berryhill GE, Gloviczki JM, Trott JF, Kraft J, Lock AL, Hovey RC. In Utero Exposure to trans-10, cis-12 Conjugated Linoleic Acid Modifies Postnatal Development of the Mammary Gland and its Hormone Responsiveness. Journal of Mammary Gland Biology and Neoplasia. Springer Science and Business Media LLC; 2021; 10.1007/s10911-021-09499-y
Conjugated Linoleic Acid and Its Beneficial Effects in Obesity, Cardiovascular Disease, and Cancer Cite
Basak S, Duttaroy AK. Conjugated Linoleic Acid and Its Beneficial Effects in Obesity, Cardiovascular Disease, and Cancer. Nutrients. MDPI AG; 2020; 12:1913 10.3390/nu12071913
Maternal and Early Postnatal Diet Supplemented with Conjugated Linoleic Acid Isomers Affect Lipid Profile in Hearts of Offspring Rats with Mammary Tumors Cite
Białek M, Białek A, Czauderna M. Maternal and Early Postnatal Diet Supplemented with Conjugated Linoleic Acid Isomers Affect Lipid Profile in Hearts of Offspring Rats with Mammary Tumors. Animals. MDPI AG; 2020; 10:464 10.3390/ani10030464
Fatty Acids of CLA-Enriched Egg Yolks Can Induce Transcriptional Activation of Peroxisome Proliferator-Activated Receptors in MCF-7 Breast Cancer Cells Cite
Koronowicz AA, Banks P, Master A, Domagała D, Piasna-Słupecka E, Drozdowska M, et al. Fatty Acids of CLA-Enriched Egg Yolks Can Induce Transcriptional Activation of Peroxisome Proliferator-Activated Receptors in MCF-7 Breast Cancer Cells. PPAR Research. Hindawi Limited; 2017; 2017:1-12 10.1155/2017/2865283
Abstract LB-A02:trans,trans-Conjugated linoleic acid induces apoptosis by enhancing gap junctional intercellular communication inhuman breast cancer MCF-7 cells Cite
Ha YL, Rakib A, Kim JO. Abstract LB-A02:trans,trans-Conjugated linoleic acid induces apoptosis by enhancing gap junctional intercellular communication inhuman breast cancer MCF-7 cells. Natural Products. American Association for Cancer Research; 2015; 10.1158/1535-7163.targ-15-lb-a02
Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks Cite
Florence ACR, Béal C, Silva RC, Bogsan CS, Pilleggi ALO, Gioielli LA, et al. Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks. Food Chemistry. Elsevier BV; 2012; 135:2207-2214 10.1016/j.foodchem.2012.07.026
Organic milk improves Bifidobacterium lactis counts and bioactive fatty acids contents in fermented milk Cite
Florence ACR, Oliveira RP, Silva RC, Soares FA, Gioielli LA, Oliveira MN. Organic milk improves Bifidobacterium lactis counts and bioactive fatty acids contents in fermented milk. LWT. Elsevier BV; 2012; 49:89-95 10.1016/j.lwt.2012.04.023
Chemical characteristics, fatty acid composition and conjugated linoleic acid (CLA) content of traditional Greek yogurts Cite
Serafeimidou A, Zlatanos S, Laskaridis K, Sagredos A. Chemical characteristics, fatty acid composition and conjugated linoleic acid (CLA) content of traditional Greek yogurts. Food Chemistry. Elsevier BV; 2012; 134:1839-1846 10.1016/j.foodchem.2012.03.102
CLA reduces breast cancer cell growth and invasion through ERα and PI3K/Akt pathways Cite
Bocca C, Bozzo F, Cannito S, Colombatto S, Miglietta A. CLA reduces breast cancer cell growth and invasion through ERα and PI3K/Akt pathways. Chemico-Biological Interactions. Elsevier BV; 2010; 183:187-193 10.1016/j.cbi.2009.09.022
Conjugated linoleic acid intake and breast cancer risk in a prospective cohort of Swedish women Cite
Larsson SC, Bergkvist L, Wolk A. Conjugated linoleic acid intake and breast cancer risk in a prospective cohort of Swedish women. The American Journal of Clinical Nutrition. Oxford University Press (OUP); 2009; 90:556-560 10.3945/ajcn.2009.27480
Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus bisporus) Cite
Chen S, Oh S, Phung S, Hur G, Ye JJ, Kwok SL, et al. Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus bisporus). Cancer Research. American Association for Cancer Research (AACR); 2006; 66:12026-12034 10.1158/0008-5472.can-06-2206
Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue Cite
Wang L, Huang Y, Liu S, Yan P, Lin YC. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC Cancer. Springer Science and Business Media LLC; 2008; 8 10.1186/1471-2407-8-208
Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer Cite
Voorrips LE, Brants HA, Kardinaal AF, Hiddink GJ, van den Brandt PA, Goldbohm RA. Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer. The American Journal of Clinical Nutrition. Oxford University Press (OUP); 2002; 76:873-882 10.1093/ajcn/76.4.873
The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium Cite
Ip MM, McGee SO, Masso-Welch PA, Ip C, Meng X, Ou L, et al. The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis. Oxford University Press (OUP); 2007; 28:1269-1276 10.1093/carcin/bgm018
Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism Cite
Roberts CG, Gurisik E, Biden TJ, Sutherland RL, Butt AJ. Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism. Molecular Cancer Therapeutics. American Association for Cancer Research (AACR); 2007; 6:2777-2785 10.1158/1535-7163.mct-07-0374