Tag: sweetPotato

News

06/09/25

Purple sweet potato extract inhibits carcinogen-induced breast cancer

Foods

• • sweet potatoes

Studies

• Protective effect of purple sweet potatoes (Ipomoea batatas L.) against rat breast cancer Cite
  Silva-Correa CR, Hilario‑Vargas J, Calderón-Peña AA, Torre VEV, Aspajo-Villalaz CL, Bailon-Moscoso N, et al. Protective effect of purple sweet potatoes (Ipomoea batatas L.) against rat breast cancer. Veterinary World. Veterinary World; 2025;:1137-1146 10.14202/vetworld.2025.1137-1146
• Antiproliferative potential of sweetpotato in breast (BT549) and lung (A549) cancer cell lines Cite
  Nwosisi S, Nandwani D, Myles EL. Antiproliferative potential of sweetpotato in breast (BT549) and lung (A549) cancer cell lines. BMC Complementary Medicine and Therapies. Springer Science and Business Media LLC; 2025; 25 10.1186/s12906-025-04770-9
• Prodelphinidin from Purple Sweet Potato Induces Apoptosis in Human Triple-Negative Breast Cancer Cells via Reactive Oxygen Species and Endoplasmic Reticulum Stress Through the Mitochondrial Apoptosis Pathways Cite
  Zhang J, Chen Z, Wang S, Kong L, Liu J. Prodelphinidin from Purple Sweet Potato Induces Apoptosis in Human Triple-Negative Breast Cancer Cells via Reactive Oxygen Species and Endoplasmic Reticulum Stress Through the Mitochondrial Apoptosis Pathways. Springer Science and Business Media LLC; 2025; 10.21203/rs.3.rs-5738324/v1
• Sweetpotatoes [Ipomoea batatas (L.) lam]: the super food of the Next Century? An intensive review on their potential as a sustainable and versatile food source for future generations Cite
  Islam S. Sweetpotatoes [Ipomoea batatas (L.) lam]: the super food of the Next Century? An intensive review on their potential as a sustainable and versatile food source for future generations. CyTA - Journal of Food. Informa UK Limited; 2024; 22 10.1080/19476337.2024.2397553
• Advances in valorization of sweet potato peels: A comprehensive review on the nutritional compositions, phytochemical profiles, nutraceutical properties, and potential industrial applications Cite
  Jiang H, Wang F, Ma R, Yang T, Liu C, Shen W, et al. Advances in valorization of sweet potato peels: A comprehensive review on the nutritional compositions, phytochemical profiles, nutraceutical properties, and potential industrial applications. Comprehensive Reviews in Food Science and Food Safety. Wiley; 2024; 23 10.1111/1541-4337.13400
• Harnessing the health benefits of purple and yellow-fleshed sweet potatoes: Phytochemical composition, stabilization methods, and industrial utilization- A review Cite
  Ivane NMA, Wang W, Ma Q, Wang J, Sun J. Harnessing the health benefits of purple and yellow-fleshed sweet potatoes: Phytochemical composition, stabilization methods, and industrial utilization- A review. Food Chemistry: X. Elsevier BV; 2024;:101462 10.1016/j.fochx.2024.101462
• Dioscorea Alata Extract as Anti-Cancer Agent by Regulating Genetic Mutations, Apoptosis, and Cell Proliferation: In Vitro and in Silico Studies Cite
  Makiyah SNN, Christina YI, Ahkam AH. Dioscorea Alata Extract as Anti-Cancer Agent by Regulating Genetic Mutations, Apoptosis, and Cell Proliferation: In Vitro and in Silico Studies. Sains Malaysiana. Penerbit Universiti Kebangsaan Malaysia (UKM Press); 2023; 52:2657-2671 10.17576/jsm-2023-5209-15
• High β-Sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals Cite
  Zhang J, Huang L, Tang X, Pan M, Ye X, Li X, et al. High β-Sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals. Food Science and Human Wellness. Tsinghua University Press; 2023; 10.26599/fshw.2022.9250225
• Recent advances on the biological activities of purple sweet potato anthocyanins Cite
  Tang C, Han J, Chen D, Zong S, Liu J, Kan J, et al. Recent advances on the biological activities of purple sweet potato anthocyanins. Food Bioscience. Elsevier BV; 2023;:102670 10.1016/j.fbio.2023.102670
• Sweet Potato Is Not Simply an Abundant Food Crop: A Comprehensive Review of Its Phytochemical Constituents, Biological Activities, and the Effects of Processing Cite
  Laveriano-Santos EP, López-Yerena A, Jaime-Rodríguez C, González-Coria J, Lamuela-Raventós RM, Vallverdú-Queralt A, et al. Sweet Potato Is Not Simply an Abundant Food Crop: A Comprehensive Review of Its Phytochemical Constituents, Biological Activities, and the Effects of Processing. Antioxidants. MDPI AG; 2022; 11:1648 10.3390/antiox11091648
• A Comparative Study on Inhibition of Breast Cancer Cells and Tumors in Mice by Carotenoid Extract and Nanoemulsion Prepared from Sweet Potato (Ipomoea batatas L.) Peel Cite
  Hsu H, Chen B. A Comparative Study on Inhibition of Breast Cancer Cells and Tumors in Mice by Carotenoid Extract and Nanoemulsion Prepared from Sweet Potato (Ipomoea batatas L.) Peel. Pharmaceutics. MDPI AG; 2022; 14:980 10.3390/pharmaceutics14050980
• In vitro digestion, absorption and biological activities of acylated anthocyanins from purple sweet potatoes (Ipomoea batatas) Cite
  de Aguiar Cipriano P, Kim H, Fang C, Paula Venancio V, Mertens-Talcott SU, Talcott ST. In vitro digestion, absorption and biological activities of acylated anthocyanins from purple sweet potatoes (Ipomoea batatas). Food Chemistry. Elsevier BV; 2021;:131076 10.1016/j.foodchem.2021.131076
• Untargeted metabolomics of purple and orange-fleshed sweet potatoes reveals a large structural diversity of anthocyanins and flavonoids Cite
  Bennett AA, Mahood EH, Fan K, Moghe GD. Untargeted metabolomics of purple and orange-fleshed sweet potatoes reveals a large structural diversity of anthocyanins and flavonoids. Scientific Reports. Springer Science and Business Media LLC; 2021; 11 10.1038/s41598-021-95901-y
• Purple Sweet Potato Phytochemicals: Potential Chemo-preventive and Anticancer Activities Cite
  Rizki Budiman M, Lina Wiraswati H, Rezano A. Purple Sweet Potato Phytochemicals: Potential Chemo-preventive and Anticancer Activities. Open Access Macedonian Journal of Medical Sciences. Scientific Foundation SPIROSKI; 2021; 9:288-298 10.3889/oamjms.2021.6784
• Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo Cite
  Tang S, Kan J, Sun R, Cai H, Hong J, Jin C, et al. Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo. Journal of Food Biochemistry. Wiley; 2021; 10.1111/jfbc.13869
• A comprehensive review of sweet potato (Ipomoea batatas [L.] Lam): Revisiting the associated health benefits Cite
  Alam MK. A comprehensive review of sweet potato (Ipomoea batatas [L.] Lam): Revisiting the associated health benefits. Trends in Food Science & Technology. Elsevier BV; 2021; 115:512-529 10.1016/j.tifs.2021.07.001
• Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion Cite
  Han B, Jiang P, Jiang L, Li X, Ye X. Three phytosterols from sweet potato inhibit MCF7-xenograft-tumor growth through modulating gut microbiota homeostasis and SCFAs secretion. Food Research International. Elsevier BV; 2021;:110147 10.1016/j.foodres.2021.110147
• Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway Cite
  Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, et al. Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway. Planta Medica. Georg Thieme Verlag KG; 2020; 86:767-775 10.1055/a-1176-1884
• Simultaneous separation and quantitation of three phytosterols from the sweet potato, and determination of their anti-breast cancer activity Cite
  Jiang P, Han B, Jiang L, Li Y, Yu Y, Xu H, et al. Simultaneous separation and quantitation of three phytosterols from the sweet potato, and determination of their anti-breast cancer activity. Journal of Pharmaceutical and Biomedical Analysis. Elsevier BV; 2019; 174:718-727 10.1016/j.jpba.2019.06.048
• Phytochemical Characterization of Five Edible Purple-Reddish Vegetables: Anthocyanins, Flavonoids, and Phenolic Acid Derivatives Cite
  Frond AD, Iuhas CI, Stirbu I, Leopold L, Socaci S, Andreea S, et al. Phytochemical Characterization of Five Edible Purple-Reddish Vegetables: Anthocyanins, Flavonoids, and Phenolic Acid Derivatives. Molecules. MDPI AG; 2019; 24:1536 10.3390/molecules24081536
• Comparative Study on the Chemical Structure and In Vitro Antiproliferative Activity of Anthocyanins in Purple Root Tubers and Leaves of Sweet Potato (Ipomoea batatas) Cite
  Vishnu VR, Renjith RS, Mukherjee A, Anil SR, Sreekumar J, Jyothi AN. Comparative Study on the Chemical Structure and In Vitro Antiproliferative Activity of Anthocyanins in Purple Root Tubers and Leaves of Sweet Potato (Ipomoea batatas). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2019; 67:2467-2475 10.1021/acs.jafc.8b05473
• Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis Cite
  Li Z, Yu Y, Wang M, Xu H, Han B, Jiang P, et al. Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis. Scientific Reports. Springer Science and Business Media LLC; 2019; 9 10.1038/s41598-018-29099-x
• Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K–Akt Signaling Pathway Cite
  Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, et al. Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K–Akt Signaling Pathway. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2018; 66:9704-9718 10.1021/acs.jafc.8b03305
• The inhibitory activity of peonidin purple sweet potato in human epidermal receptor-2 receptor (her-2) expression by in silico study Cite
  Laksmiani NPL, Widiastari MI, Reynaldi KR. The inhibitory activity of peonidin purple sweet potato in human epidermal receptor-2 receptor (her-2) expression by in silico study. Journal of Physics: Conference Series. IOP Publishing; 2018; 1040:012010 10.1088/1742-6596/1040/1/012010
• Estrogenic Effects of the Extracts from the Chinese Yam (Dioscorea opposite Thunb.) and Its Effective Compounds in Vitro and in Vivo Cite
  Zeng M, Zhang L, Li M, Zhang B, Zhou N, Ke Y, et al. Estrogenic Effects of the Extracts from the Chinese Yam (Dioscorea opposite Thunb.) and Its Effective Compounds in Vitro and in Vivo. Molecules. MDPI AG; 2018; 23:11 10.3390/molecules23020011
• A review of therapeutic potentials of sweet potato: Pharmacological activities and influence of the cultivar Cite
  Ayeleso TB, Ramachela K, Mukwevho E. A review of therapeutic potentials of sweet potato: Pharmacological activities and influence of the cultivar. Tropical Journal of Pharmaceutical Research. African Journals Online (AJOL); 2017; 15:2751 10.4314/tjpr.v15i12.31
• Roots and Tuber Crops as Functional Foods: A Review on Phytochemical Constituents and Their Potential Health Benefits Cite
  Chandrasekara A, Josheph Kumar T. Roots and Tuber Crops as Functional Foods: A Review on Phytochemical Constituents and Their Potential Health Benefits. International Journal of Food Science. Hindawi Limited; 2016; 2016:1-15 10.1155/2016/3631647
• Anti-Inflammatory and Anticancer Activities of Taiwanese Purple-Fleshed Sweet Potatoes (Ipomoea batatas L. Lam) Extracts Cite
  Sugata M, Lin C, Shih Y. Anti-Inflammatory and Anticancer Activities of Taiwanese Purple-Fleshed Sweet Potatoes (Ipomoea batatas L. Lam) Extracts. BioMed Research International. Hindawi Limited; 2015; 2015:1-10 10.1155/2015/768093
• In vitroantioxidant, antimicrobial and anti-proliferative activities of purple potato extracts (Solanum tuberosumcv Vitelotte noire) following simulated gastro-intestinal digestion Cite
  Ombra MN, Fratianni F, Granese T, Cardinale F, Cozzolino A, Nazzaro F. In vitroantioxidant, antimicrobial and anti-proliferative activities of purple potato extracts (Solanum tuberosumcv Vitelotte noire) following simulated gastro-intestinal digestion. Natural Product Research. Informa UK Limited; 2014; 29:1087-1091 10.1080/14786419.2014.981183
• Ipomoea batatas (L.) Lam.: A Rich Source of Lipophilic Phytochemicals Cite
  Cordeiro N, Freitas N, Faria M, Gouveia M. Ipomoea batatas (L.) Lam.: A Rich Source of Lipophilic Phytochemicals. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2013; 61:12380-12384 10.1021/jf404230z
• Functional Characterization of Dihydroflavonol-4-Reductase in Anthocyanin Biosynthesis of Purple Sweet Potato Underlies the Direct Evidence of Anthocyanins Function against Abiotic Stresses Cite
  Wang H, Fan W, Li H, Yang J, Huang J, Zhang P. Functional Characterization of Dihydroflavonol-4-Reductase in Anthocyanin Biosynthesis of Purple Sweet Potato Underlies the Direct Evidence of Anthocyanins Function against Abiotic Stresses. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e78484 10.1371/journal.pone.0078484
• Antioxidant Activity of Flavonoids from Sweet Potato Vines In Vitro Cite
  Li YC. Antioxidant Activity of Flavonoids from Sweet Potato Vines In Vitro. Advanced Materials Research. Trans Tech Publications, Ltd.; 2011; 236-238:2634-2638 10.4028/www.scientific.net/amr.236-238.2634
• Distribution of phenolic compounds and antioxidative activities in parts of sweet potato (Ipomoea batata L.) plants and in home processed roots Cite
  Jung J, Lee S, Kozukue N, Levin CE, Friedman M. Distribution of phenolic compounds and antioxidative activities in parts of sweet potato (Ipomoea batata L.) plants and in home processed roots. Journal of Food Composition and Analysis. Elsevier BV; 2011; 24:29-37 10.1016/j.jfca.2010.03.025
• Anthocyanin changes in the Korean purple-fleshed sweet potato, Shinzami, as affected by steaming and baking Cite
  Kim HW, Kim JB, Cho SM, Chung MN, Lee YM, Chu SM, et al. Anthocyanin changes in the Korean purple-fleshed sweet potato, Shinzami, as affected by steaming and baking. Food Chemistry. Elsevier BV; 2012; 130:966-972 10.1016/j.foodchem.2011.08.031
• Phenolic compound profile of selected vegetables frequently consumed by African Americans in the southeast United States Cite
  Huang Z, Wang B, Eaves DH, Shikany JM, Pace RD. Phenolic compound profile of selected vegetables frequently consumed by African Americans in the southeast United States. Food Chemistry. Elsevier BV; 2007; 103:1395-1402 10.1016/j.foodchem.2006.10.077
• Potential Chemopreventive Properties of Extract from Baked Sweet Potato (Ipomoea batatasLam. Cv. Koganesengan) Cite
  Rabah IO, Hou D, Komine S, Fujii M. Potential Chemopreventive Properties of Extract from Baked Sweet Potato (Ipomoea batatasLam. Cv. Koganesengan). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2004; 52:7152-7157 10.1021/jf049368w