Tag: seaweed

News

11/17/11

Brown seaweed compound fucoidan induces breast cancer cell death

Foods

• • seaweed

Studies

• Fucoidan extract from brown seaweed (Sargassum echinocarpum): molecular weight, elemental composition, selectivity and anticancer activity against breast cancer cells Cite
  Yunianta Y, Laeliocattleya RA, Wulan SN, Risjani Y. Fucoidan extract from brown seaweed (Sargassum echinocarpum): molecular weight, elemental composition, selectivity and anticancer activity against breast cancer cells. Natural Product Research. Informa UK Limited; 2024;:1-9 10.1080/14786419.2024.2326978
• Development of a novel method for the extraction of phycocyanin pigment from Spirulina platensis and assessment of its antioxidant, antimicrobial, and anticancer activities Cite
  Bougatef H, Hadrich F, Gazbar M, Sila A, Chamkha M, Bougatef A. Development of a novel method for the extraction of phycocyanin pigment from Spirulina platensis and assessment of its antioxidant, antimicrobial, and anticancer activities. Biomass Conversion and Biorefinery. Springer Science and Business Media LLC; 2024; 10.1007/s13399-024-05540-2
• Abstract 7303: The algal carotenoid diatoxanthin shows anti-cancer and cardio-protective properties: RNA seq analysis of potential targets Cite
  Noonan DM, Calabrone L, Pistelli L, Brunet C, Sansone C, Morelli D, et al. Abstract 7303: The algal carotenoid diatoxanthin shows anti-cancer and cardio-protective properties: RNA seq analysis of potential targets. Cancer Research. American Association for Cancer Research (AACR); 2024; 84:7303-7303 10.1158/1538-7445.am2024-7303
• Algae-derived bioactive compounds as potential nutraceuticals for cancer therapy: A comprehensive review Cite
  Minhas LA, Kaleem M, Farooqi HMU, Kausar F, Waqar R, Bhatti T, et al. Algae-derived bioactive compounds as potential nutraceuticals for cancer therapy: A comprehensive review. Algal Research. Elsevier BV; 2024;:103396 10.1016/j.algal.2024.103396
• Fucoidan’s Molecular Targets: A Comprehensive Review of Its Unique and Multiple Targets Accounting for Promising Bioactivities Supported by In Silico Studies Cite
  Zayed A, Al-Saedi DA, Mensah EO, Kanwugu ON, Adadi P, Ulber R. Fucoidan’s Molecular Targets: A Comprehensive Review of Its Unique and Multiple Targets Accounting for Promising Bioactivities Supported by In Silico Studies. Marine Drugs. MDPI AG; 2023; 22:29 10.3390/md22010029
• Brown seaweed phenolics and photosynthetic pigments: Bioavailability, challenges, and potential applications in food industries Cite
  Pangestuti R, Susanto E, Siahaan EA, Munarwoh HSH, Ningrum A, Purnamayati L. Brown seaweed phenolics and photosynthetic pigments: Bioavailability, challenges, and potential applications in food industries. Journal of Applied Pharmaceutical Science. Open Science Publishers LLP; 2024; 10.7324/japs.2024.121531
• The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells Cite
  Ahmed SA, Mendonca P, Messeha SS, Oriaku ET, Soliman KFA. The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells. Molecules. MDPI AG; 2023; 29:61 10.3390/molecules29010061
• Opportunities and challenges of fucoidan for tumors therapy Cite
  Yu H, Zhang Q, Farooqi AA, Wang J, Yue Y, Geng L, et al. Opportunities and challenges of fucoidan for tumors therapy. Carbohydrate Polymers. Elsevier BV; 2023;:121555 10.1016/j.carbpol.2023.121555
• In silico molecular docking, molecular dynamics, ADMET analysis of fucoidan against receptor frizzled-8 and coreceptor LRP6 in Wnt/β-Catenin pathway and in vitro analysis of fucoidan extract from Sargassum echinocarpum as β-catenin inhibitor in breast cancer cell line (MCF-7) Cite
  Laeliocattleya RA, Yunianta Y, Risjani Y, Wulan SN. In silico molecular docking, molecular dynamics, ADMET analysis of fucoidan against receptor frizzled-8 and coreceptor LRP6 in Wnt/β-Catenin pathway and in vitro analysis of fucoidan extract from Sargassum echinocarpum as β-catenin inhibitor in breast cancer cell line (MCF-7). Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2023;:1-16 10.1080/07391102.2023.2265488
• Advances in oligosaccharides production from brown seaweeds: extraction, characterization, antimetabolic syndrome, and other potential applications Cite
  Krishna Perumal P, Huang C, Chen C, Anisha GS, Singhania RR, Dong C, et al. Advances in oligosaccharides production from brown seaweeds: extraction, characterization, antimetabolic syndrome, and other potential applications. Bioengineered. Informa UK Limited; 2023; 14 10.1080/21655979.2023.2252659
• Structure and Metabolically Oriented Efficacy of Fucoidan from Brown Alga Sargassum muticum in the Model of Colony Formation of Melanoma and Breast Cancer Cells Cite
  Usoltseva RV, Zueva AO, Malyarenko OS, Anastyuk SD, Moiseenko OP, Isakov VV, et al. Structure and Metabolically Oriented Efficacy of Fucoidan from Brown Alga Sargassum muticum in the Model of Colony Formation of Melanoma and Breast Cancer Cells. Marine Drugs. MDPI AG; 2023; 21:486 10.3390/md21090486
• Recent advances in marine oligosaccharides: A review of bioactivities and application Cite
  Luan T, Hu S, Nie W, Liu J, Wang S, Jia L, et al. Recent advances in marine oligosaccharides: A review of bioactivities and application. Journal of Functional Foods. Elsevier BV; 2023; 108:105754 10.1016/j.jff.2023.105754
• Therapeutic Potential of Haematococcus pluvialis in the Field of Drug Delivery Cite
  Kumar TS, Josephine A, Dharani G. Therapeutic Potential of Haematococcus pluvialis in the Field of Drug Delivery. Haematococcus. Springer Nature Singapore; 2023;:181-210 10.1007/978-981-99-2901-6_12
• Novel Fucoidan Pharmaceutical Formulations and Their Potential Application in Oncology—A Review Cite
  Zahariev N, Katsarov P, Lukova P, Pilicheva B. Novel Fucoidan Pharmaceutical Formulations and Their Potential Application in Oncology—A Review. Polymers. MDPI AG; 2023; 15:3242 10.3390/polym15153242
• Effective Isolation of Brown Seaweed Flavonoids with Their Potential to Inhibit Free Radicals and Proliferative Cells Cite
  Vinodkumar M, Packirisamy ASB. Effective Isolation of Brown Seaweed Flavonoids with Their Potential to Inhibit Free Radicals and Proliferative Cells. Journal of Inorganic and Organometallic Polymers and Materials. Springer Science and Business Media LLC; 2023; 10.1007/s10904-023-02738-1
• Production of high- and low-molecular weight fucoidan fragments with defined sulfation patterns and heightened in vitro anticancer activity against TNBC cells using novel endo-fucanases of the GH107 family Cite
  Zueva AO, Silchenko AS, Rasin AB, Malyarenko OS, Kusaykin MI, Kalinovsky AI, et al. Production of high- and low-molecular weight fucoidan fragments with defined sulfation patterns and heightened in vitro anticancer activity against TNBC cells using novel endo-fucanases of the GH107 family. Carbohydrate Polymers. Elsevier BV; 2023;:121128 10.1016/j.carbpol.2023.121128
• Therapeutic Potential of Polyphenols and Other Micronutrients of Marine Origin Cite
  Pereira L, Cotas J. Therapeutic Potential of Polyphenols and Other Micronutrients of Marine Origin. Marine Drugs. MDPI AG; 2023; 21:323 10.3390/md21060323
• Marine Carotenoid Fucoxanthin as a Promising Anticancer Therapeutic Against Triple-Negative Breast Cancer (TNBC) Cite
  Ahmed S, Mendonca P, Messeha SS, Soliman KF. Marine Carotenoid Fucoxanthin as a Promising Anticancer Therapeutic Against Triple-Negative Breast Cancer (TNBC). ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development. American Society for Pharmacology and Experimental Therapeutics; 2023; 10.1124/jpet.122.176370
• Green seaweed Caulerpa racemosa - Chemical constituents, cytotoxicity in breast cancer cells and molecular docking simulation Cite
  Sanger G, Wonggo D, Taher N, Dotulong V, Setiawan AA, Permatasari HK, et al. Green seaweed Caulerpa racemosa - Chemical constituents, cytotoxicity in breast cancer cells and molecular docking simulation. Journal of Agriculture and Food Research. Elsevier BV; 2023; 12:100621 10.1016/j.jafr.2023.100621
• Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry Cite
  Mensah EO, Kanwugu ON, Panda PK, Adadi P. Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry. Food Hydrocolloids. Elsevier BV; 2023;:108784 10.1016/j.foodhyd.2023.108784
• An extensive review of marine pigments: sources, biotechnological applications, and sustainability Cite
  Muñoz-Miranda LA, Iñiguez-Moreno M. An extensive review of marine pigments: sources, biotechnological applications, and sustainability. Aquatic Sciences. Springer Science and Business Media LLC; 2023; 85 10.1007/s00027-023-00966-8
• Biological activity of algal derived carrageenan: A comprehensive review in light of human health and disease Cite
  Pradhan B, Ki J. Biological activity of algal derived carrageenan: A comprehensive review in light of human health and disease. International Journal of Biological Macromolecules. Elsevier BV; 2023; 238:124085 10.1016/j.ijbiomac.2023.124085
• An overview on the nutritional and bioactive components of green seaweeds Cite
  Xu J, Liao W, Liu Y, Guo Y, Jiang S, Zhao C. An overview on the nutritional and bioactive components of green seaweeds. Food Production, Processing and Nutrition. Springer Science and Business Media LLC; 2023; 5 10.1186/s43014-023-00132-5
• In vitro Anticancer potential of Laminarin and Fucoidan from Brown seaweeds Cite
  Sanniyasi E, G RK, Damotharan R, A A, S M, S N, et al. In vitro Anticancer potential of Laminarin and Fucoidan from Brown seaweeds. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2444953/v1
• A Review on Fucoidan Structure, Extraction Techniques, and Its Role as an Immunomodulatory Agent Cite
  Jayawardena TU, Nagahawatta DP, Fernando IPS, Kim Y, Kim J, Kim W, et al. A Review on Fucoidan Structure, Extraction Techniques, and Its Role as an Immunomodulatory Agent. Marine Drugs. MDPI AG; 2022; 20:755 10.3390/md20120755
• Chemical characterization, antiproliferative activity and molecular docking of bioactive compounds from brown algae Fucus spiralis Cite
  Imane B, Laila B, Fouzia H, Ismail G, Ahmed E, Kaoutar B, et al. Chemical characterization, antiproliferative activity and molecular docking of bioactive compounds from brown algae Fucus spiralis. Algal Research. Elsevier BV; 2022; 68:102887 10.1016/j.algal.2022.102887
• Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets Cite
  Mumu M, Das A, Emran TB, Mitra S, Islam F, Roy A, et al. Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets. Frontiers in Pharmacology. Frontiers Media SA; 2022; 13 10.3389/fphar.2022.929442
• Alternative proteins for meat and dairy replacers: Food safety and future trends Cite
  Banach JL, van der Berg JP, Kleter G, van Bokhorst-van de Veen H, Bastiaan-Net S, Pouvreau L, et al. Alternative proteins for meat and dairy replacers: Food safety and future trends. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2022;:1-18 10.1080/10408398.2022.2089625
• Fucoxanthinol Promotes Apoptosis in MCF-7 and MDA-MB-231 Cells by Attenuating Laminins–Integrins Axis Cite
  Yasuda A, Wagatsuma M, Murase W, Kubota A, Kojima H, Ohta T, et al. Fucoxanthinol Promotes Apoptosis in MCF-7 and MDA-MB-231 Cells by Attenuating Laminins–Integrins Axis. Onco. MDPI AG; 2022; 2:145-163 10.3390/onco2030010
• Fucoxanthin Is a Potential Therapeutic Agent for the Treatment of Breast Cancer Cite
  Lau T, Kwan H. Fucoxanthin Is a Potential Therapeutic Agent for the Treatment of Breast Cancer. Marine Drugs. MDPI AG; 2022; 20:370 10.3390/md20060370
• Anticancer effects of the Xanthophyll Fucoxanthin on Genetically Different Triple‐Negative Breast Cancer Cells Cite
  Ahmed S, Mendonca P, Badisa R, Messeha SS, Soliman KFA. Anticancer effects of the Xanthophyll Fucoxanthin on Genetically Different Triple‐Negative Breast Cancer Cells. The FASEB Journal. Wiley; 2022; 36 10.1096/fasebj.2022.36.s1.r2303
• Isolation, Characterization, and Biological Activities of Fucoidan Derived from Ceratophyllum Submersum L. Cite
  Hoang NN, Nguyen TK, Vo TH, Nguyen NH, Nguyen DH, Tran DL. Isolation, Characterization, and Biological Activities of Fucoidan Derived from Ceratophyllum Submersum L.. Macromolecular Research. Springer Science and Business Media LLC; 2022; 30:136-145 10.1007/s13233-022-0010-3
• Algae as an emerging source of bioactive pigments Cite
  Patel AK, Albarico FPJB, Perumal PK, Vadrale AP, Ntan CT, Chau HTB, et al. Algae as an emerging source of bioactive pigments. Bioresource Technology. Elsevier BV; 2022;:126910 10.1016/j.biortech.2022.126910
• Antitumor activity of fucoidan: a systematic review and meta-analysis Cite
  Cao L, Sun Z, Makale EC, Du G, Long W, Huang H. Antitumor activity of fucoidan: a systematic review and meta-analysis. Translational Cancer Research. AME Publishing Company; 2021; 10:5390-5405 10.21037/tcr-21-1733
• Immunomodulatory effects of polysaccharides from marine algae for treating cancer, infectious disease, and inflammation Cite
  Hwang J, Yadav D, Lee PC, Jin J. Immunomodulatory effects of polysaccharides from marine algae for treating cancer, infectious disease, and inflammation. Phytotherapy Research. Wiley; 2021; 10.1002/ptr.7348
• Tumor preventive properties of selected marine pigments against colon and breast cancer Cite
  Manochkumar J, Doss CGP, Efferth T, Ramamoorthy S. Tumor preventive properties of selected marine pigments against colon and breast cancer. Algal Research. Elsevier BV; 2022; 61:102594 10.1016/j.algal.2021.102594
• Inhibition of fucoidan on breast cancer cells and potential enhancement of their sensitivity to chemotherapy by regulating autophagy Cite
  Zhang N, Xue M, Wang Q, Liang H, Yang J, Pei Z, et al. Inhibition of fucoidan on breast cancer cells and potential enhancement of their sensitivity to chemotherapy by regulating autophagy. Phytotherapy Research. Wiley; 2021; 10.1002/ptr.7303
• Fungi and Algae as Sources of Medicinal and Other Biologically Active Compounds: A Review Cite
  Ślusarczyk J, Adamska E, Czerwik-Marcinkowska J. Fungi and Algae as Sources of Medicinal and Other Biologically Active Compounds: A Review. Nutrients. MDPI AG; 2021; 13:3178 10.3390/nu13093178
• The Therapeutic Potential of the Anticancer Activity of Fucoidan: Current Advances and Hurdles Cite
  Jin J, Chauhan PS, Arukha AP, Chavda V, Dubey A, Yadav D. The Therapeutic Potential of the Anticancer Activity of Fucoidan: Current Advances and Hurdles. Marine Drugs. MDPI AG; 2021; 19:265 10.3390/md19050265
• Are Cyanotoxins the Only Toxic Compound Potentially Present in Microalgae Supplements? Results from a Study of Ecological and Non-Ecological Products Cite
  Sánchez-Parra E, Boutarfa S, Aboal M. Are Cyanotoxins the Only Toxic Compound Potentially Present in Microalgae Supplements? Results from a Study of Ecological and Non-Ecological Products. Toxins. MDPI AG; 2020; 12:552 10.3390/toxins12090552
• On a Beam of Light: Photoprotective Activities of the Marine Carotenoids Astaxanthin and Fucoxanthin in Suppression of Inflammation and Cancer Cite
  Catanzaro E, Bishayee A, Fimognari C. On a Beam of Light: Photoprotective Activities of the Marine Carotenoids Astaxanthin and Fucoxanthin in Suppression of Inflammation and Cancer. Marine Drugs. MDPI AG; 2020; 18:544 10.3390/md18110544
• Fucoidan-Doxorubicin Nanoparticles Targeting P-Selectin for Effective Breast Cancer Therapy Cite
  Jafari M, Sriram V, Xu Z, Harris GM, Lee J. Fucoidan-Doxorubicin Nanoparticles Targeting P-Selectin for Effective Breast Cancer Therapy. Carbohydrate Polymers. Elsevier BV; 2020; 249:116837 10.1016/j.carbpol.2020.116837
• The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes Cite
  Eid SY, Althubiti MA, Abdallah ME, Wink M, El-Readi MZ. The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. Phytomedicine. Elsevier BV; 2020; 77:153280 10.1016/j.phymed.2020.153280
• A review on fucoidan antitumor strategies: From a biological active agent to a structural component of fucoidan-based systems Cite
  Oliveira C, Neves NM, Reis RL, Martins A, Silva TH. A review on fucoidan antitumor strategies: From a biological active agent to a structural component of fucoidan-based systems. Carbohydrate Polymers. Elsevier BV; 2020; 239:116131 10.1016/j.carbpol.2020.116131
• Fucoidan from Laminaria japonica exerts antitumor effects on angiogenesis and micrometastasis in triple-negative breast cancer cells Cite
  Hsu W, Lin M, Kuo T, Chou C, Mi F, Cheng C, et al. Fucoidan from Laminaria japonica exerts antitumor effects on angiogenesis and micrometastasis in triple-negative breast cancer cells. International Journal of Biological Macromolecules. Elsevier BV; 2020; 149:600-608 10.1016/j.ijbiomac.2020.01.256
• “Fucoidan, a natural biopolymer in cancer combating: From edible algae to nanocarrier tailoring” Cite
  Etman SM, Elnaggar YS, Abdallah OY. “Fucoidan, a natural biopolymer in cancer combating: From edible algae to nanocarrier tailoring”. International Journal of Biological Macromolecules. Elsevier BV; 2020; 147:799-808 10.1016/j.ijbiomac.2019.11.191
• Fucoidan Promotes Apoptosis and Inhibits EMT of Breast Cancer Cells Cite
  He X, Xue M, Jiang S, Li W, Yu J, Xiang S. Fucoidan Promotes Apoptosis and Inhibits EMT of Breast Cancer Cells. Biological and Pharmaceutical Bulletin. Pharmaceutical Society of Japan; 2019; 42:442-447 10.1248/bpb.b18-00777
• Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin Cite
  Pawar VK, Singh Y, Sharma K, Shrivastav A, Sharma A, Singh A, et al. Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin. International Journal of Biological Macromolecules. Elsevier BV; 2019; 122:1100-1114 10.1016/j.ijbiomac.2018.09.059
• Structural characterization and anticancer activity (MCF7 and MDA-MB-231) of polysaccharides fractionated from brown seaweed Sargassum wightii Cite
  Vaikundamoorthy R, Krishnamoorthy V, Vilwanathan R, Rajendran R. Structural characterization and anticancer activity (MCF7 and MDA-MB-231) of polysaccharides fractionated from brown seaweed Sargassum wightii. International Journal of Biological Macromolecules. Elsevier BV; 2018; 111:1229-1237 10.1016/j.ijbiomac.2018.01.125
• The effect of fucoidan on intestinal flora and intestinal barrier function in rats with breast cancer Cite
  Xue M, Ji X, Liang H, Liu Y, Wang B, Sun L, et al. The effect of fucoidan on intestinal flora and intestinal barrier function in rats with breast cancer. Food & Function. Royal Society of Chemistry (RSC); 2018; 9:1214-1223 10.1039/c7fo01677h
• In vitro investigating of anticancer activity of focuxanthin from marine brown seaweed species Cite
  Karkhane Yousefi M, Seyed Hashtroudi M, Mashinchian Moradi A, Ghasempour A. In vitro investigating of anticancer activity of focuxanthin from marine brown seaweed species. Global Journal of Environmental Science and Management. ISWA Society; 2018; 4 10.22034/gjesm.2018.04.01.008
• Oral administration of lyophilizedDunaliella salina, a carotenoid-rich marine alga, reduces tumor progression in mammary cancer induced rats Cite
  Srinivasan R, Chaitanyakumar A, Mageswari A, Gomathi A, Pavan Kumar JGS, Jayasindu M, et al. Oral administration of lyophilizedDunaliella salina, a carotenoid-rich marine alga, reduces tumor progression in mammary cancer induced rats. Food & Function. Royal Society of Chemistry (RSC); 2017; 8:4517-4527 10.1039/c7fo01328k
• Isolation, Structural characterization, and antiproliferative activity of phycocolloids from the red seaweed Laurencia papillosa on MCF-7 human breast cancer cells Cite
  Ghannam A, Murad H, Jazzara M, Odeh A, Allaf AW. Isolation, Structural characterization, and antiproliferative activity of phycocolloids from the red seaweed Laurencia papillosa on MCF-7 human breast cancer cells. International Journal of Biological Macromolecules. Elsevier BV; 2018; 108:916-926 10.1016/j.ijbiomac.2017.11.001
• Cytotoxicity of Fucoidan from Three Tropical Brown Algae Against Breast and Colon Cancer Cell Lines Cite
  Isnansetyo A, Laili Lutfia FN, Nursid M, T T, Susidarti RA. Cytotoxicity of Fucoidan from Three Tropical Brown Algae Against Breast and Colon Cancer Cell Lines. Pharmacognosy Journal. EManuscript Services; 2016; 9:14-20 10.5530/pj.2017.1.3
• Brown Seaweed Fucoidan Inhibits Cancer Progression by Dual Regulation of mir-29c/ADAM12 and miR-17-5p/PTEN Axes in Human Breast Cancer Cells Cite
  Wu S, Yan M, Wu AT, Yuan KS, Liu SH. Brown Seaweed Fucoidan Inhibits Cancer Progression by Dual Regulation of mir-29c/ADAM12 and miR-17-5p/PTEN Axes in Human Breast Cancer Cells. Journal of Cancer. Ivyspring International Publisher; 2016; 7:2408-2419 10.7150/jca.15703
• Cytoprotective effect of seaweeds with high antioxidant activity from the Peniche coast (Portugal) Cite
  Pinteus S, Silva J, Alves C, Horta A, Fino N, Rodrigues AI, et al. Cytoprotective effect of seaweeds with high antioxidant activity from the Peniche coast (Portugal). Food Chemistry. Elsevier BV; 2017; 218:591-599 10.1016/j.foodchem.2016.09.067
• Structure and cytotoxic activity of ulvan extracted from green seaweed Ulva lactuca Cite
  Thanh TTT, Quach TMT, Nguyen TN, Vu Luong D, Bui ML, Tran TTV. Structure and cytotoxic activity of ulvan extracted from green seaweed Ulva lactuca. International Journal of Biological Macromolecules. Elsevier BV; 2016; 93:695-702 10.1016/j.ijbiomac.2016.09.040
• Changes in rats' breast tumor ultrastructure and immune and messenger RNA responses caused by dietary Seaweed (Kappaphycus alvarezii) extract Cite
  Mohamed S, Bakar N, Tengku Ibrahim T, Mohamad Shalan N. Changes in rats' breast tumor ultrastructure and immune and messenger RNA responses caused by dietary Seaweed (Kappaphycus alvarezii) extract. Journal of Microscopy and Ultrastructure. Medknow; 2017; 5:70 10.1016/j.jmau.2016.08.001
• Lipids, Fatty Acids, and Fucoxanthin Content from Temperate and Tropical Brown Seaweeds Cite
  Susanto E, Fahmi AS, Abe M, Hosokawa M, Miyashita K. Lipids, Fatty Acids, and Fucoxanthin Content from Temperate and Tropical Brown Seaweeds. Aquatic Procedia. Elsevier BV; 2016; 7:66-75 10.1016/j.aqpro.2016.07.009
• A microalga, Euglena tuba induces apoptosis and suppresses metastasis in human lung and breast carcinoma cells through ROS-mediated regulation of MAPKs Cite
  Panja S, Ghate NB, Mandal N. A microalga, Euglena tuba induces apoptosis and suppresses metastasis in human lung and breast carcinoma cells through ROS-mediated regulation of MAPKs. Cancer Cell International. Springer Science and Business Media LLC; 2016; 16 10.1186/s12935-016-0330-5
• Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum Cite
  Senthilkumar D, Jayanthi S. Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum. Journal of Functional Foods. Elsevier BV; 2016; 25:323-332 10.1016/j.jff.2016.06.010
• Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer Cite
  Pádua D, Rocha E, Gargiulo D, Ramos A. Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer. Phytochemistry Letters. Elsevier BV; 2015; 14:91-98 10.1016/j.phytol.2015.09.007
• Toxic elements and speciation in seafood samples from different contaminated sites in Europe Cite
  Maulvault A, Anacleto P, Barbosa V, Sloth JJ, Rasmussen R, Tediosi A, et al. Toxic elements and speciation in seafood samples from different contaminated sites in Europe. Environmental Research. Elsevier BV; 2015; 143:72-81 10.1016/j.envres.2015.09.016
• Fucoidan Induces Cancer Cell Apoptosis by Modulating the Endoplasmic Reticulum Stress Cascades Cite
  Chen S, Zhao Y, Zhang Y, Zhang D. Fucoidan Induces Cancer Cell Apoptosis by Modulating the Endoplasmic Reticulum Stress Cascades. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e108157 10.1371/journal.pone.0108157
• Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in breast cancer cells Cite
  Shirahata S, Zhang Z, Yoshida T, Eto H, Teruya K. Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in breast cancer cells. BMC Proceedings. Springer Science and Business Media LLC; 2013; 7 10.1186/1753-6561-7-s6-p70
• Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer Cite
  Senthilkumar K, Manivasagan P, Venkatesan J, Kim S. Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer. International Journal of Biological Macromolecules. Elsevier BV; 2013; 60:366-374 10.1016/j.ijbiomac.2013.06.030
• The fucoidans from brown algae of Far-Eastern seas: Anti-tumor activity and structure–function relationship Cite
  Vishchuk OS, Ermakova SP, Zvyagintseva TN. The fucoidans from brown algae of Far-Eastern seas: Anti-tumor activity and structure–function relationship. Food Chemistry. Elsevier BV; 2013; 141:1211-1217 10.1016/j.foodchem.2013.03.065
• Anti-inflammatory activity of edible brown alga Saccharina japonica and its constituents pheophorbide a and pheophytin a in LPS-stimulated RAW 264.7 macrophage cells Cite
  Islam MN, Ishita IJ, Jin SE, Choi RJ, Lee CM, Kim YS, et al. Anti-inflammatory activity of edible brown alga Saccharina japonica and its constituents pheophorbide a and pheophytin a in LPS-stimulated RAW 264.7 macrophage cells. Food and Chemical Toxicology. Elsevier BV; 2013; 55:541-548 10.1016/j.fct.2013.01.054
• Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2–ARE pathway Cite
  Wang R, Paul VJ, Luesch H. Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2–ARE pathway. Free Radical Biology and Medicine. Elsevier BV; 2013; 57:141-153 10.1016/j.freeradbiomed.2012.12.019
• Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo Cite
  Xue M, Ge Y, Zhang J, Wang Q, Hou L, Liu Y, et al. Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e43483 10.1371/journal.pone.0043483
• Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cells Cite
  Jeong B, Ko E, Joo H. Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cells. Food and Chemical Toxicology. Elsevier BV; 2012; 50:1480-1484 10.1016/j.fct.2012.01.034
• Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways Cite
  Zhang Z, Teruya K, Eto H, Shirahata S. Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways. PLoS ONE. Public Library of Science (PLoS); 2011; 6:e27441 10.1371/journal.pone.0027441
• Fucoidan Induces Apoptosis through Activation of Caspase-8 on Human Breast Cancer MCF-7 Cells Cite
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