Tag: rhubarb
Rhubarb: The red or green stalk of the rhubarb plant (Rheum rhabarbarum). Rhubarb leaves are poisonous and should not be eaten.
Foods
Studies
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Rhein and hesperidin nanoparticles remodel tumor immune microenvironment by reducing CAFs and CCL2 secreted by CAAs for efficient triple-negative breast cancer therapy
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Huang J, Zhang H, Ma L, Ma N, Luo N, Jin W, et al. Rhein and hesperidin nanoparticles remodel tumor immune microenvironment by reducing CAFs and CCL2 secreted by CAAs for efficient triple-negative breast cancer therapy. International Immunopharmacology. Elsevier BV; 2024; 141:113001 10.1016/j.intimp.2024.113001
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Phytochemical‐mediated modulation of autophagy and endoplasmic reticulum stress as a cancer therapeutic approach
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Al Azzani M, Nizami ZN, Magramane R, Sekkal MN, Eid AH, Al Dhaheri Y, et al. Phytochemical‐mediated modulation of autophagy and endoplasmic reticulum stress as a cancer therapeutic approach. Phytotherapy Research. Wiley; 2024; 10.1002/ptr.8283
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The Himalayan rhubarb (Rheum australe D. Don.): an endangered medicinal herb with immense ethnobotanical ‘use-value’
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Hussain A, Aslam M, Masoodi TH, Bhat MA, Kongala PR, Husaini AM. The Himalayan rhubarb (Rheum australe D. Don.): an endangered medicinal herb with immense ethnobotanical ‘use-value’. Vegetos. Springer Science and Business Media LLC; 2024; 10.1007/s42535-024-00877-5
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Rhein potentiates doxorubicin in treating triple negative breast cancer by inhibiting cancer-associated fibroblasts
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Xu S, Zheng S, Ma N, Zhang H, Shi J, Huang J, et al. Rhein potentiates doxorubicin in treating triple negative breast cancer by inhibiting cancer-associated fibroblasts. Biochemical Pharmacology. Elsevier BV; 2024;:116139 10.1016/j.bcp.2024.116139
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Evaluation of the anthraquinone drug rhein at IC50 on T-47D breast cancer cell lines based on analytical methods
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Heidari P, Shekardasht MB, Alipour A, Mehraei N. Evaluation of the anthraquinone drug rhein at IC50 on T-47D breast cancer cell lines based on analytical methods. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3166253/v1
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Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe?
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López-Moreno M, Garcés-Rimón M, Miguel M. Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe?. Journal of Functional Foods. Elsevier BV; 2022; 89:104938 10.1016/j.jff.2022.104938
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Advances in the study of emodin: an update on pharmacological properties and mechanistic basis
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Zheng Q, Li S, Li X, Liu R. Advances in the study of emodin: an update on pharmacological properties and mechanistic basis. Chinese Medicine. Springer Science and Business Media LLC; 2021; 16 10.1186/s13020-021-00509-z
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A Water-Soluble Antibiotic in Rhubarb Stalk Shows an Unusual Pattern of Multiple Zones of Inhibition and Preferentially Kills Slow-Growing Bacteria
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Bhattacharjee MK, Bommareddy PK, DePass AL. A Water-Soluble Antibiotic in Rhubarb Stalk Shows an Unusual Pattern of Multiple Zones of Inhibition and Preferentially Kills Slow-Growing Bacteria. Antibiotics. MDPI AG; 2021; 10:951 10.3390/antibiotics10080951
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Emodin - A natural anthraquinone derivative with diverse pharmacological activities
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Semwal RB, Semwal DK, Combrinck S, Viljoen A. Emodin - A natural anthraquinone derivative with diverse pharmacological activities. Phytochemistry. Elsevier BV; 2021; 190:112854 10.1016/j.phytochem.2021.112854
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Identification of rhein as the metabolite responsible for toxicity of rhubarb anthraquinones
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Cheng Y, Zhang H, Qu L, He Y, Routledge MN, Yun Gong Y, et al. Identification of rhein as the metabolite responsible for toxicity of rhubarb anthraquinones. Food Chemistry. Elsevier BV; 2020; 331:127363 10.1016/j.foodchem.2020.127363
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Rheum rhaponticum and Rheum rhabarbarum: a review of phytochemistry, biological activities and therapeutic potential
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Kolodziejczyk-Czepas J, Liudvytska O. Rheum rhaponticum and Rheum rhabarbarum: a review of phytochemistry, biological activities and therapeutic potential. Phytochemistry Reviews. Springer Science and Business Media LLC; 2020; 10.1007/s11101-020-09715-3
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Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer
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Bhattacharjee M, Upadhyay P, Sarker S, Basu A, Das S, Ghosh A, et al. Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer. Biochimica et Biophysica Acta (BBA) - General Subjects. Elsevier BV; 2020; 1864:129695 10.1016/j.bbagen.2020.129695
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A Stilbenoid Isorhapontigenin as a Potential Anti-Cancer Agent against Breast Cancer through Inhibiting Sphingosine Kinases/Tubulin Stabilization
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Subedi L, Teli MK, Lee JH, Gaire BP, Kim M, Kim SY. A Stilbenoid Isorhapontigenin as a Potential Anti-Cancer Agent against Breast Cancer through Inhibiting Sphingosine Kinases/Tubulin Stabilization. Cancers. MDPI AG; 2019; 11:1947 10.3390/cancers11121947
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Anti-proliferative and apoptotic effects of Rheum emodi on human breast adenocarcinoma, MCF-7 Cells, and antimicrobial effectiveness against selected bacterial strains
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Rais J, Arshad M, Jafri A, Bano S, Shivnath N, Tripathi M. Anti-proliferative and apoptotic effects of Rheum emodi on human breast adenocarcinoma, MCF-7 Cells, and antimicrobial effectiveness against selected bacterial strains. Pharmacognosy Magazine. Medknow; 2019; 15:237 10.4103/pm.pm_674_18
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Antioxidant, Antibacterial and Antiproliferative Activities of Turkish Rhubarb (Rheum palmatum L.) Leaf Extracts
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Berköz M, Yıldırım M, Allahverdiyev O, Krośniak M, Francik R, Bozan N, et al. Antioxidant, Antibacterial and Antiproliferative Activities of Turkish Rhubarb (Rheum palmatum L.) Leaf Extracts. Proceedings. MDPI AG; 2017; 1:1032 10.3390/proceedings1101032
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Effect of Emodin on Expression of VEGF-A and VEGFR_2 Genes in Human Breast Carcinoma MCF-7 Cell
Cite
Cheshmi F, Kazerouni F, Omrani MD, Rahimipour A, Shanaki M, Dehghan -Nayeri N, et al. Effect of Emodin on Expression of VEGF-A and VEGFR_2 Genes in Human Breast Carcinoma MCF-7 Cell. International Journal of Cancer Management. Kowsar Medical Institute; 2017; 10 10.5812/ijcm.8095
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Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma
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Su Z, Tian W, Li J, Wang C, Pan Z, Li D, et al. Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma. Journal of Molecular Structure. Elsevier BV; 2017; 1147:462-468 10.1016/j.molstruc.2017.06.123
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Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells
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Tseng H, Wang Y, Tzeng Y, Chen D, Liao Y, Chiu H, et al. Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells. The American Journal of Chinese Medicine. World Scientific Pub Co Pte Lt; 2017; 45:337-350 10.1142/s0192415x17500215
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Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells
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Ma J, Hung C, Lin Y, Ho C, Kao J, Way T. Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. Oncotarget. Impact Journals, LLC; 2016; 7:58915-58930 10.18632/oncotarget.10410
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Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages
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Iwanowycz S, Wang J, Hodge J, Wang Y, Yu F, Fan D. Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages. Molecular Cancer Therapeutics. American Association for Cancer Research (AACR); 2016; 15:1931-1942 10.1158/1535-7163.mct-15-0987
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Essiac® and Flor-Essence® herbal tonics stimulate the in vitro growth of human breast cancer cells
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Kulp KS, Montgomery JL, Nelson DO, Cutter B, Latham ER, Shattuck DL, et al. Essiac® and Flor-Essence® herbal tonics stimulate the in vitro growth of human breast cancer cells. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2006; 98:249-259 10.1007/s10549-005-9156-x
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Synergy of Taxol and rhein lysinate associated with the downregulation of ERK activation in lung carcinoma cells
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ZHEN Y, HU G, ZHAO Y, YAN F, LI R, GAO J, et al. Synergy of Taxol and rhein lysinate associated with the downregulation of ERK activation in lung carcinoma cells. Oncology Letters. Spandidos Publications; 2013; 6:525-528 10.3892/ol.2013.1398
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Piceatannol Suppresses Breast Cancer Cell Invasion through the Inhibition of MMP-9: Involvement of PI3K/AKT and NF-κB Pathways
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Ko HS, Lee H, Kim S, Lee E. Piceatannol Suppresses Breast Cancer Cell Invasion through the Inhibition of MMP-9: Involvement of PI3K/AKT and NF-κB Pathways. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2012; 60:4083-4089 10.1021/jf205171g
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Emodin inhibits TNF-α-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis
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Heo S, Yun H, Park W, Park S. Emodin inhibits TNF-α-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis. Journal of Cellular Biochemistry. Wiley; 2008; 105:70-80 10.1002/jcb.21805
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Anti-angiogenic effects of rhubarb and its anthraquinone derivatives
Cite
He Z, He M, Ma S, But PP. Anti-angiogenic effects of rhubarb and its anthraquinone derivatives. Journal of Ethnopharmacology. Elsevier BV; 2009; 121:313-317 10.1016/j.jep.2008.11.008
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Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC)
Cite
Zick SM, Sen A, Feng Y, Green J, Olatunde S, Boon H. Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC). The Journal of Alternative and Complementary Medicine. Mary Ann Liebert Inc; 2006; 12:971-980 10.1089/acm.2006.12.971