Tag: radiosensitizer

Articles

• Foods to eat and avoid during radiation treatment

News

01/23/18

Resveratrol sensitizes ER+/PR+ cells to radiation treatment

11/02/16

Enterolactone increases radiation-induced breast cancer cell death

05/27/13

Calorie restriction heightens effects of radiotherapy in TN tumors

11/18/11

Metformin may increase the effectiveness of radiation treatment

Studies

• Enhancement of Radiation therapy for Breast Cancer through Combined Treatment with Indole-3-Carbinol in combination with Resveratrol: Assessment of EMT Biomarkers and Effects on Cell Proliferation Cite
  Essa z, Rady M, Abdraboh M, Khalifa M. Enhancement of Radiation therapy for Breast Cancer through Combined Treatment with Indole-3-Carbinol in combination with Resveratrol: Assessment of EMT Biomarkers and Effects on Cell Proliferation. Journal of Environmental Sciences. Mansoura University. Egyptian Knowledge Bank; 2024; 0:0-0 10.21608/joese.2024.262215.1039
• Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect Cite
  Zhu L, Yang K, Ren Z, Yin D, Zhou Y. Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect. Translational Oncology. Elsevier BV; 2024; 44:101945 10.1016/j.tranon.2024.101945
• Abstract 707: Calorie restriction to augment radiation response in models of Black women with breast cancer Cite
  Francois NB, Shastri AA, Harding S, DeAngelis T, Adekeye A, Simone N. Abstract 707: Calorie restriction to augment radiation response in models of Black women with breast cancer. Cancer Research. American Association for Cancer Research (AACR); 2024; 84:707-707 10.1158/1538-7445.am2024-707
• Effect of bisphosphonates and statins on the in vitro radiosensitivity of breast cancer cell lines Cite
  Bodgi L, Bou-Gharios J, Azzi J, Challita R, Feghaly C, Baalbaki K, et al. Effect of bisphosphonates and statins on the in vitro radiosensitivity of breast cancer cell lines. Pharmacological Reports. Springer Science and Business Media LLC; 2023; 10.1007/s43440-023-00560-7
• Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy Cite
  Klement RJ, Figueroa J, Weigel M, Champ CE, Ok S, Sweeney RA. Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy. Holistic Integrative Oncology. Springer Science and Business Media LLC; 2023; 2 10.1007/s44178-023-00058-5
• Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK Cite
  Shaheer K, Prabhu BS, Ali HS, Lakshmanan-M D. Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK. Phytomedicine. Elsevier BV; 2023;:155126 10.1016/j.phymed.2023.155126
• Low‐dose aspirin can inhibit exosomal release induced by radiotherapy in breast cancer and attenuate its inhibitory effect on NK cell proliferation Cite
  Wang L, Hu Z, Chen C, Chen T, Yao Z, Li W, et al. Low‐dose aspirin can inhibit exosomal release induced by radiotherapy in breast cancer and attenuate its inhibitory effect on NK cell proliferation. Cancer Medicine. Wiley; 2023; 10.1002/cam4.6274
• Synergistic effect of chrysin and radiotherapy against triple-negative breast cancer (TNBC) cell lines Cite
  Jafari S, Dabiri S, Mehdizadeh Aghdam E, Fathi E, Saeedi N, Montazersaheb S, et al. Synergistic effect of chrysin and radiotherapy against triple-negative breast cancer (TNBC) cell lines. Clinical and Translational Oncology. Springer Science and Business Media LLC; 2023; 10.1007/s12094-023-03141-5
• Estrogen Receptor-positive Breast Cancer Cells are Sensitized by Piperine to Chemo/Radio Therapy through Lowering the expression of a NHEJ repair protein DNA-PK Cite
  Shaheer K, Prabhu S, Ali HS, Lakshmanan D. Estrogen Receptor-positive Breast Cancer Cells are Sensitized by Piperine to Chemo/Radio Therapy through Lowering the expression of a NHEJ repair protein DNA-PK. Research Square Platform LLC; 2022; 10.21203/rs.3.rs-2401099/v1
• Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells Cite
  Khozooei S, Lettau K, Barletta F, Jost T, Rebholz S, Veerappan S, et al. Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells. Journal of Experimental & Clinical Cancer Research. Springer Science and Business Media LLC; 2022; 41 10.1186/s13046-022-02442-x
• Melatonin Modulation of Radiation-Induced Molecular Changes in MCF-7 Human Breast Cancer Cells Cite
  Alonso-González C, González-Abalde C, Menéndez-Menéndez J, González-González A, Álvarez-García V, González-Cabeza A, et al. Melatonin Modulation of Radiation-Induced Molecular Changes in MCF-7 Human Breast Cancer Cells. Biomedicines. MDPI AG; 2022; 10:1088 10.3390/biomedicines10051088
• Radiomitigation by Melatonin in C57BL/6 Mice: Possible Implications as Adjuvant in Radiotherapy and Chemotherapy Cite
  TRIPATHI AM, KHAN S, CHAUDHURY NK. Radiomitigation by Melatonin in C57BL/6 Mice: Possible Implications as Adjuvant in Radiotherapy and Chemotherapy. In Vivo. Anticancer Research USA Inc.; 2022; 36:1203-1221 10.21873/invivo.12820
• Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models Cite
  Michmerhuizen AR, Lerner LM, Pesch AM, Ward C, Schwartz R, Wilder-Romans K, et al. Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models. npj Breast Cancer. Springer Science and Business Media LLC; 2022; 8 10.1038/s41523-022-00397-y
• Modulation of the Tumor Microenvironment with Trastuzumab Enables Radiosensitization in HER2+ Breast Cancer Cite
  Song PN, Mansur A, Lu Y, Della Manna D, Burns A, Samuel S, et al. Modulation of the Tumor Microenvironment with Trastuzumab Enables Radiosensitization in HER2+ Breast Cancer. Cancers. MDPI AG; 2022; 14:1015 10.3390/cancers14041015
• Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment Cite
  Xue P, Zhang G, Zhang J, Ren L. Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment. Phytomedicine. Elsevier BV; 2022; 99:153998 10.1016/j.phymed.2022.153998
• Polyphenols, Luteolin and Pelargonidin, Modulate Radio- and Chemo-Sensitivity on Breast Cancer Cite
  El-Sheikh MM, Abdel-Naby DH, EL-Hamoly T. Polyphenols, Luteolin and Pelargonidin, Modulate Radio- and Chemo-Sensitivity on Breast Cancer. Egyptian Journal of Radiation Sciences and Applications. Egypts Presidential Specialized Council for Education and Scientific Research; 2022; 0:0-0 10.21608/ejrsa.2022.113425.1127
• Radiosensitizing Effect of Bromelain Using Tumor Mice Model via Ki-67 and PARP-1 Inhibition Cite
  Mekkawy MH, Fahmy HA, Nada AS, Ali OS. Radiosensitizing Effect of Bromelain Using Tumor Mice Model via Ki-67 and PARP-1 Inhibition. Integrative Cancer Therapies. SAGE Publications; 2021; 20:153473542110603 10.1177/15347354211060369
• Curcumin Administered in Combination with Glu-GNPs Induces Radiosensitivity in Transplanted Tumor MDA-MB-231-luc Cells in Nude Mice Cite
  Li M, Lin L, Guo T, Wu Y, Lin J, Liu Y, et al. Curcumin Administered in Combination with Glu-GNPs Induces Radiosensitivity in Transplanted Tumor MDA-MB-231-luc Cells in Nude Mice. BioMed Research International. Hindawi Limited; 2021; 2021:1-11 10.1155/2021/9262453
• Inhibition of Estrogen Receptor Signaling as a Strategy for Radiosensitization of ER+ Breast Cancers Cite
  Michmerhuizen A, Pesch A, Schwartz R, Wilder-Romans K, Liu M, Harold A, et al. Inhibition of Estrogen Receptor Signaling as a Strategy for Radiosensitization of ER+ Breast Cancers. International Journal of Radiation Oncology*Biology*Physics. Elsevier BV; 2021; 111:e253 10.1016/j.ijrobp.2021.07.842
• Does omega-3 PUFA-enriched oral nutritional intervention benefit cancer patients receiving chemo (radio) therapy? A systematic review and meta-analysis of randomized controlled trials Cite
  Wang Y, Liu R, Chang M, Wei W, Guo Y, Jin Q, et al. Does omega-3 PUFA-enriched oral nutritional intervention benefit cancer patients receiving chemo (radio) therapy? A systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2021;:1-16 10.1080/10408398.2021.1984199
• Abstract 737: Estrogen receptor inhibition with tamoxifen mediates radiosensitization of ER+ breast cancer models Cite
  Michmerhuizen AR, Pesch AM, Schwartz R, Wilder-Romans K, Liu M, Azaria R, et al. Abstract 737: Estrogen receptor inhibition with tamoxifen mediates radiosensitization of ER+ breast cancer models. Endocrinology. American Association for Cancer Research; 2021; 10.1158/1538-7445.am2021-737
• Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation Cite
  Yang K, Hou Y, Zhang Y, Liang H, Sharma A, Zheng W, et al. Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation. Journal of Experimental Medicine. Rockefeller University Press; 2021; 218 10.1084/jem.20201915
• Simvastatin treatment varies the radiation response of human breast cells in 2D or 3D culture Cite
  Manda K, Juerß D, Fischer P, Schröder A, Koenen A, Hildebrandt G. Simvastatin treatment varies the radiation response of human breast cells in 2D or 3D culture. Investigational New Drugs. Springer Science and Business Media LLC; 2020; 10.1007/s10637-020-01046-6
• Berberine can amplify cytotoxic effect of radiotherapy by targeting cancer stem cells Cite
  El-Benhawy SA, El-Sheredy HG, Ghanem HB, Abo El-Soud AA. Berberine can amplify cytotoxic effect of radiotherapy by targeting cancer stem cells. Breast Cancer Management. Future Medicine Ltd; 2020; 9:BMT41 10.2217/bmt-2020-0007
• The impact on clinical outcomes of post-operative radiation therapy delay after neoadjuvant chemotherapy in patients with breast cancer: A multicentric international study Cite
  Marta GN, AlBeesh R, Pereira AAL, Oliveira LJ, Mano MS, Hijal T. The impact on clinical outcomes of post-operative radiation therapy delay after neoadjuvant chemotherapy in patients with breast cancer: A multicentric international study. The Breast. Elsevier BV; 2020; 54:46-51 10.1016/j.breast.2020.08.013
• Melatonin as a Radio-Sensitizer in Cancer Cite
  Alonso-González C, González A, Menéndez-Menéndez J, Martínez-Campa C, Cos S. Melatonin as a Radio-Sensitizer in Cancer. Biomedicines. MDPI AG; 2020; 8:247 10.3390/biomedicines8080247
• Resveratrol induces apoptosis and attenuates proliferation of MCF-7 cells in combination with radiation and hyperthermia. Cite
  Amini P, Nodooshan SJ, Ashrafizadeh M, Eftekhari S, Aryafar T, Khalafi L, et al. Resveratrol induces apoptosis and attenuates proliferation of MCF-7 cells in combination with radiation and hyperthermia.. Current Molecular Medicine. Bentham Science Publishers Ltd.; 2020; 20 10.2174/1566524020666200521080953
• Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin Cite
  Nguyen YT, Moon JY, Ediriweera MK, Cho SK. Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin. Cancers. MDPI AG; 2020; 12:268 10.3390/cancers12020268
• Radiosensitizing effect of curcumin-loaded lipid nanoparticles in breast cancer cells Cite
  Minafra L, Porcino N, Bravatà V, Gaglio D, Bonanomi M, Amore E, et al. Radiosensitizing effect of curcumin-loaded lipid nanoparticles in breast cancer cells. Scientific Reports. Springer Science and Business Media LLC; 2019; 9 10.1038/s41598-019-47553-2
• Effect of resveratrol on the radiosensitivity of 5‐FU in human breast cancer MCF‐7 cells Cite
  Aghamiri S, Jafarpour A, Zandsalimi F, Aghemiri M, Shoja M. Effect of resveratrol on the radiosensitivity of 5‐FU in human breast cancer MCF‐7 cells. Journal of Cellular Biochemistry. Wiley; 2019; 120:15671-15677 10.1002/jcb.28836
• Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation Cite
  Giallourou NS, Rowland IR, Rothwell SD, Packham G, Commane DM, Swann JR. Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation. European Journal of Nutrition. Springer Science and Business Media LLC; 2018; 58:2377-2391 10.1007/s00394-018-1789-8
• The in vitro radiosensitizer potential of resveratrol on MCF-7 breast cancer cells Cite
  da Costa Araldi IC, Bordin FPR, Cadoná FC, Barbisan F, Azzolin VF, Teixeira CF, et al. The in vitro radiosensitizer potential of resveratrol on MCF-7 breast cancer cells. Chemico-Biological Interactions. Elsevier BV; 2018; 282:85-92 10.1016/j.cbi.2018.01.013
• Response to Radiotherapy After Breast-Conserving Surgery in Different Breast Cancer Subtypes in the Swedish Breast Cancer Group 91 Radiotherapy Randomized Clinical Trial Cite
  Sjöström M, Lundstedt D, Hartman L, Holmberg E, Killander F, Kovács A, et al. Response to Radiotherapy After Breast-Conserving Surgery in Different Breast Cancer Subtypes in the Swedish Breast Cancer Group 91 Radiotherapy Randomized Clinical Trial. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2017; 35:3222-3229 10.1200/jco.2017.72.7263
• Pharmacology of natural radioprotectors Cite
  Mun G, Kim S, Choi E, Kim CS, Lee Y. Pharmacology of natural radioprotectors. Archives of Pharmacal Research. Springer Science and Business Media LLC; 2018; 41:1033-1050 10.1007/s12272-018-1083-6
• Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma Cite
  Su Z, Tian W, Li J, Wang C, Pan Z, Li D, et al. Biological evaluation and molecular docking of Rhein as a multi-targeted radiotherapy sensitization agent of nasopharyngeal carcinoma. Journal of Molecular Structure. Elsevier BV; 2017; 1147:462-468 10.1016/j.molstruc.2017.06.123
• Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis Cite
  Bigdeli B, Goliaei B, Masoudi-Khoram N, Jooyan N, Nikoofar A, Rouhani M, et al. Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. Toxicology and Applied Pharmacology. Elsevier BV; 2016; 313:180-194 10.1016/j.taap.2016.10.021
• HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo Cite
  Hou J, Zhou Z, Chen X, Zhao R, Yang Z, Wei N, et al. HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo. Oncotarget. Impact Journals, LLC; 2016; 7:45186-45198 10.18632/oncotarget.9870
• Melatonin: Antiproliferative Actions and Protection of Normal Tissue and Enhancement of Radiosensitivity of Breast Cancer Cells Cite
  Martinez Campa C. Melatonin: Antiproliferative Actions and Protection of Normal Tissue and Enhancement of Radiosensitivity of Breast Cancer Cells. Journal of Cell Science & Therapy. OMICS Publishing Group; 2016; 07 10.4172/2157-7013.1000241
• Caffeic Acid Phenethyl Ester Increases Radiosensitivity of Estrogen Receptor-Positive and -Negative Breast Cancer Cells by Prolonging Radiation-Induced DNA Damage Cite
  Khoram NM, Bigdeli B, Nikoofar A, Goliaei B. Caffeic Acid Phenethyl Ester Increases Radiosensitivity of Estrogen Receptor-Positive and -Negative Breast Cancer Cells by Prolonging Radiation-Induced DNA Damage. Journal of Breast Cancer. Korean Breast Cancer Society; 2016; 19:18 10.4048/jbc.2016.19.1.18
• Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis Cite
  Velho‑Pereira R, Kumar A, Pandey BN, Jagtap AG, Mishra KP. Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis. Cell Biology International. Wiley; 2011; 35:1025-1029 10.1042/cbi20100701
• Melatonin enhancement of the radiosensitivity of human breast cancer cells is associated with the modulation of proteins involved in estrogen biosynthesis Cite
  Alonso-González C, González A, Martínez-Campa C, Menéndez-Menéndez J, Gómez-Arozamena J, García-Vidal A, et al. Melatonin enhancement of the radiosensitivity of human breast cancer cells is associated with the modulation of proteins involved in estrogen biosynthesis. Cancer Letters. Elsevier BV; 2016; 370:145-152 10.1016/j.canlet.2015.10.015
• Radioprotective effects of genistein on HL-7702 cells via the inhibition of apoptosis and DNA damage Cite
  Song L, Ma L, Cong F, Shen X, Jing P, Ying X, et al. Radioprotective effects of genistein on HL-7702 cells via the inhibition of apoptosis and DNA damage. Cancer Letters. Elsevier BV; 2015; 366:100-111 10.1016/j.canlet.2015.06.008
• Piperine inhibits the growth and motility of triple-negative breast cancer cells Cite
  Greenshields AL, Doucette CD, Sutton KM, Madera L, Annan H, Yaffe PB, et al. Piperine inhibits the growth and motility of triple-negative breast cancer cells. Cancer Letters. Elsevier BV; 2015; 357:129-140 10.1016/j.canlet.2014.11.017
• Caloric restriction augments radiation efficacy in breast cancer Cite
  Saleh A, Simone B, Palazzo J, Savage JE, Sano Y, Dan T, et al. Caloric restriction augments radiation efficacy in breast cancer. Cell Cycle. Informa UK Limited; 2013; 12:1955-1963 10.4161/cc.25016
• Nutrient Restriction and Radiation Therapy for Cancer Treatment: When Less Is More Cite
  Champ CE, Baserga R, Mishra MV, Jin L, Sotgia F, Lisanti MP, et al. Nutrient Restriction and Radiation Therapy for Cancer Treatment: When Less Is More. The Oncologist. Wiley; 2013; 18:97-103 10.1634/theoncologist.2012-0164
• Breast Cancer Stem Cell-Like Cells Are More Sensitive to Ionizing Radiation than Non-Stem Cells: Role of ATM Cite
  Kim S, Rhee JG, Song X, Prochownik EV, Spitz DR, Lee YJ. Breast Cancer Stem Cell-Like Cells Are More Sensitive to Ionizing Radiation than Non-Stem Cells: Role of ATM. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e50423 10.1371/journal.pone.0050423
• Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo Cite
  Lin C, Yu Y, Zhao H, Yang A, Yan H, Cui Y. Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo. Radiotherapy and Oncology. Elsevier BV; 2012; 104:395-400 10.1016/j.radonc.2011.10.023
• Abstract C74: Eradicating cancer stem cells by targeting mTOR pathway with metformin. Cite
  Park HJ, Lee H, Williams B, Song CW. Abstract C74: Eradicating cancer stem cells by targeting mTOR pathway with metformin.. mTOR / PI3-Kinase. American Association for Cancer Research; 2011; 10.1158/1535-7163.targ-11-c74
• Abstract 1405: Radiosensitization of breast cancer cells by Vitamin D3 and Vitamin D analogs Cite
  Wilson E. Abstract 1405: Radiosensitization of breast cancer cells by Vitamin D3 and Vitamin D analogs. Tumor Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-1405
• Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB–regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis Cite
  Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M, et al. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB–regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis. Blood. American Society of Hematology; 2008; 111:4880-4891 10.1182/blood-2007-10-117994
• The Chemopreventive Flavonoid Apigenin Confers Radiosensitizing Effect in Human Tumor Cells Grown as Monolayers and Spheroids Cite
  WATANABE N, HIRAYAMA R, KUBOTA N. The Chemopreventive Flavonoid Apigenin Confers Radiosensitizing Effect in Human Tumor Cells Grown as Monolayers and Spheroids. Journal of Radiation Research. Oxford University Press (OUP); 2007; 48:45-50 10.1269/jrr.0635
• Resveratrol Imparts Photoprotection of Normal Cells and Enhances the Efficacy of Radiation Therapy in Cancer Cells Cite
  Reagan-Shaw S, Mukhtar H, Ahmad N. Resveratrol Imparts Photoprotection of Normal Cells and Enhances the Efficacy of Radiation Therapy in Cancer Cells. Photochemistry and Photobiology. Wiley; 2008; 84:415-421 10.1111/j.1751-1097.2007.00279.x
• Do Antioxidants Interfere With Radiation Therapy for Cancer? Cite
  Moss RW. Do Antioxidants Interfere With Radiation Therapy for Cancer?. Integrative Cancer Therapies. SAGE Publications; 2007; 6:281-292 10.1177/1534735407305655