Tag: pumpkin

Pumpkin: The fruit of a type of winter squash vine (Cucurbita maxima). Like watermelon, cucumber, zucchini and other types of squash, pumpkin belongs to the cucurbitaceae (gourd) family.

Foods

- pumpkins

Studies

In-vitro assessment of anti-breast cancer potential of pumpkin seed oil nanoemulsion with mechanistic insights into cytotoxicity and apoptosis Cite
Ghosh R, Fatima N, Vafa A, Rizvi SAR, Wajid S. In-vitro assessment of anti-breast cancer potential of pumpkin seed oil nanoemulsion with mechanistic insights into cytotoxicity and apoptosis. Scientific Reports. Springer Science and Business Media LLC; 2025; 15 10.1038/s41598-025-12532-3
Green-synthesized silver nanoparticles from peel extract of pumpkin as a potent radiosensitizer against triple-negative breast cancer (TNBC) Cite
Montazersaheb S, Eftekhari A, Shafaroodi A, Tavakoli S, Jafari S, Baran A, et al. Green-synthesized silver nanoparticles from peel extract of pumpkin as a potent radiosensitizer against triple-negative breast cancer (TNBC). Cancer Nanotechnology. Springer Science and Business Media LLC; 2024; 15 10.1186/s12645-024-00285-z
Anti-Cancer Potency of Cucurbitacin D through PI3K and AKT1: A Molecular Docking Studies Cite
Suprahman NY, Al-Bari R, Putri RA, Saputra MY, Sarmoko . Anti-Cancer Potency of Cucurbitacin D through PI3K and AKT1: A Molecular Docking Studies. Advances in Biological Sciences Research. Atlantis Press International BV; 2024;:4-10 10.2991/978-94-6463-431-0_2
Synthetic Modifications of Therapeutically Relevant Pre-assembled Cucurbitacins: Synthetic Strategies and Structure-Activity Relationships Cite
Sharma R, Thakur S, Natish , Kumar M, Vamsi K, Jachak S, et al. Synthetic Modifications of Therapeutically Relevant Pre-assembled Cucurbitacins: Synthetic Strategies and Structure-Activity Relationships. Journal of Molecular Structure. Elsevier BV; 2024;:138321 10.1016/j.molstruc.2024.138321
Beyond Insoluble Dietary Fiber: Bioactive Compounds in Plant Foods Cite
Timm M, Offringa LC, Van Klinken BJ, Slavin J. Beyond Insoluble Dietary Fiber: Bioactive Compounds in Plant Foods. Nutrients. MDPI AG; 2023; 15:4138 10.3390/nu15194138
Recent Advances in the Application of Cucurbitacins as Anticancer Agents Cite
Zieniuk B, Pawełkowicz M. Recent Advances in the Application of Cucurbitacins as Anticancer Agents. Metabolites. MDPI AG; 2023; 13:1081 10.3390/metabo13101081
Pumpkin seed oil: A comprehensive review of extraction methods, nutritional constituents and health benefits Cite
Hu Z, Hu C, Li Y, Jiang Q, Li Q, Fang C. Pumpkin seed oil: A comprehensive review of extraction methods, nutritional constituents and health benefits. Journal of the Science of Food and Agriculture. Wiley; 2023; 10.1002/jsfa.12952
Supplementation with extract of pumpkin seeds exerts estrogenic effects upon the uterine, serum lipids, mammary glands, and bone density in ovariectomized rats Cite
Lestari B, Walidah Z, Utomo RY, Murwanti R, Meiyanto E. Supplementation with extract of pumpkin seeds exerts estrogenic effects upon the uterine, serum lipids, mammary glands, and bone density in ovariectomized rats. Phytotherapy Research. Wiley; 2019; 33:891-900 10.1002/ptr.6280
Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells Cite
Richter D, Abarzua S, Chrobak M, Vrekoussis T, Weissenbacher T, Kuhn C, et al. Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells. Nutrition and Cancer. Informa UK Limited; 2013; 65:739-745 10.1080/01635581.2013.797000
Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells Cite
Saeed ME, Boulos JC, Elhaboub G, Rigano D, Saab A, Loizzo MR, et al. Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells. Phytomedicine. Elsevier BV; 2019; 62:152945 10.1016/j.phymed.2019.152945
Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein Cite
Lu J, Zhang Y, Sun M, Liu M, Wang X. Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein. Phytomedicine. Elsevier BV; 2017; 26:1-10 10.1016/j.phymed.2017.01.004
Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery Cite
Hall JA, Seedarala S, Rice N, Kopel L, Halaweish F, Blagg BSJ. Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery. Journal of Natural Products. American Chemical Society (ACS); 2015; 78:873-879 10.1021/acs.jnatprod.5b00054
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cite
Kong Y, Chen J, Zhou Z, Xia H, Qiu M, Chen C. Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e103760 10.1371/journal.pone.0103760
Comparison of the chemical compositions and nutritive values of various pumpkin (Cucurbitaceae) species and parts Cite
Kim MY, Kim EJ, Kim Y, Choi C, Lee B. Comparison of the chemical compositions and nutritive values of various pumpkin (Cucurbitaceae) species and parts. Nutrition Research and Practice. The Korean Nutrition Society and The Korean Society of Community Nutrition; 2012; 6:21 10.4162/nrp.2012.6.1.21
Physicochemical, technological properties, and health-benefits of Cucurbita moschata Duchense vs. Cehualca Cite
Jacobo-Valenzuela N, Maróstica-Junior MR, Zazueta-Morales JdJ, Gallegos-Infante JA. Physicochemical, technological properties, and health-benefits of Cucurbita moschata Duchense vs. Cehualca. Food Research International. Elsevier BV; 2011; 44:2587-2593 10.1016/j.foodres.2011.04.039
Chemical composition and profile characterisation of pumpkin (Cucurbita maxima) seed oil Cite
Rezig L, Chouaibi M, Msaada K, Hamdi S. Chemical composition and profile characterisation of pumpkin (Cucurbita maxima) seed oil. Industrial Crops and Products. Elsevier BV; 2012; 37:82-87 10.1016/j.indcrop.2011.12.004
Influence of Pumpkin Seed Oil Supplementation on Cardiovascular and Histological Outcomes in Female Non‐ovariectomized and Ovariectomized Rats Cite
Lyttle KA, Gossell‐Williams MD, Clarke T, Gardner M, Simon O. Influence of Pumpkin Seed Oil Supplementation on Cardiovascular and Histological Outcomes in Female Non‐ovariectomized and Ovariectomized Rats. The FASEB Journal. Wiley; 2008; 22 10.1096/fasebj.22.1_supplement.719.12