Tag: myricetin

News

10/09/25

Myricetin reduces doxorubicin-induced heart damage in rats

Foods

• • cranberries
  • currants
  • fennel
  • parsley

Studies

• In-silico and In-vivo Investigations Reveal Ameliorative Potential of Myricetin Against Doxorubicin-induced Myocardial Damage via Modulation of NF-κB Signaling Pathway Cite
  Barote PG, Pawar HD, Sayyed M, Awathale SN, Nakhate KT, Rathod SS, et al. In-silico and In-vivo Investigations Reveal Ameliorative Potential of Myricetin Against Doxorubicin-induced Myocardial Damage via Modulation of NF-κB Signaling Pathway. Current Protein & Peptide Science. Bentham Science Publishers Ltd.; 2025; 26 10.2174/0113892037383576250909075917
• Myricetin Prevents Doxorubicin-Induced Oxidative Stress and Mitochondrial Apoptotic Pathway in H9C2 Cardiac Cells Cite
  Aminzadeh A. Myricetin Prevents Doxorubicin-Induced Oxidative Stress and Mitochondrial Apoptotic Pathway in H9C2 Cardiac Cells. Springer Science and Business Media LLC; 2025; 10.21203/rs.3.rs-7226100/v1
• Mechanistic Insights into Flavonoid Subclasses as Cardioprotective Agents Against Doxorubicin-Induced Cardiotoxicity: A Comprehensive Review Cite
  Shang W, Li X, Zeng L, Li Z, Hu Y, Wen H, et al. Mechanistic Insights into Flavonoid Subclasses as Cardioprotective Agents Against Doxorubicin-Induced Cardiotoxicity: A Comprehensive Review. Drug Design, Development and Therapy. Informa UK Limited; 2025; Volume 19:5553-5596 10.2147/dddt.s535517
• Nanoemulsion of myricetin enhances its anti-tumor activity in nude mice of triple-negative breast cancer xenografts Cite
  Sharma P, Rai Y, Khan MA, Bhatt AN, Najmi AK, Chaturvedi S, et al. Nanoemulsion of myricetin enhances its anti-tumor activity in nude mice of triple-negative breast cancer xenografts. Frontiers in Oncology. Frontiers Media SA; 2025; 15 10.3389/fonc.2025.1563076
• Myricetin protects against doxorubicin-induced acute kidney injury in rats by mitigating oxidative damage and apoptotic response Cite
  Karadogan MT, Cicek B, Cinisli KT, Mendil AS, Ozkaraca M, Yilmaz F, et al. Myricetin protects against doxorubicin-induced acute kidney injury in rats by mitigating oxidative damage and apoptotic response. Frontiers in Pharmacology. Frontiers Media SA; 2025; 16 10.3389/fphar.2025.1601628
• Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin Cite
  Milliana A, Sari RA, Miranda SA, Mutiah R. Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin. Biomedical and Pharmacology Journal. Oriental Scientific Publishing Company; 2025; 18:835-847 10.13005/bpj/3133
• Myricetin, a natural inhibitor of CD147, increases sensitivity of cisplatin in ovarian cancer Cite
  Chen L, Fan T, Wang M, Zhu C, Feng W, Li Y, et al. Myricetin, a natural inhibitor of CD147, increases sensitivity of cisplatin in ovarian cancer. Expert Opinion on Therapeutic Targets. Informa UK Limited; 2024; 28:83-95 10.1080/14728222.2024.2306345
• Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin Cite
  Milliana A, Sari RA, Miranda SA, Mutiah R. Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin. Biomedical and Pharmacology Journal. Oriental Scientific Publishing Company; 2025; 18:835-847 10.13005/bpj/3133
• Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer Cite
  Casari G, Romaldi B, Scirè A, Minnelli C, Marzioni D, Ferretti G, et al. Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer. Biomolecules. MDPI AG; 2024; 15:15 10.3390/biom15010015
• Myricetin inhibits 4 T1 breast tumor growth in mice via induction of Nrf-2/GPX4 pathway-mediated Ferroptosis Cite
  Niu X, Ding X, Tong Q, Huang X, Ma X, Li Z, et al. Myricetin inhibits 4 T1 breast tumor growth in mice via induction of Nrf-2/GPX4 pathway-mediated Ferroptosis. Toxicology and Applied Pharmacology. Elsevier BV; 2024;:116990 10.1016/j.taap.2024.116990
• Nanoemulsion potentiates the anti-cancer activity of Myricetin by effective inhibition of PI3K/AKT/mTOR pathway in triple-negative breast cancer cells Cite
  Sharma P, Chaturvedi S, Khan MA, Rai Y, Bhatt AN, Najmi AK, et al. Nanoemulsion potentiates the anti-cancer activity of Myricetin by effective inhibition of PI3K/AKT/mTOR pathway in triple-negative breast cancer cells. Medical Oncology. Springer Science and Business Media LLC; 2024; 41 10.1007/s12032-023-02274-5
• Myricetin 3-rhamnoside retards the proliferation of hormone-independent breast cancer cells by targeting hyaluronidase Cite
  Singh S, Maurya AK, Meena A, Mishra N, Luqman S. Myricetin 3-rhamnoside retards the proliferation of hormone-independent breast cancer cells by targeting hyaluronidase. Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2023;:1-12 10.1080/07391102.2023.2256872
• Enhanced Drug Delivery, G2/M Cell Cycle Arrest and Apoptosis Induced by Myricetin-Loaded Nanogels in MCF-7 Breast Cancer Cells Cite
  Kumar NSD, Rejeeth C, Ragunathan SCB, Muthusamy G, Ramesh T, Palvannan T. Enhanced Drug Delivery, G2/M Cell Cycle Arrest and Apoptosis Induced by Myricetin-Loaded Nanogels in MCF-7 Breast Cancer Cells. Journal of Cluster Science. Springer Science and Business Media LLC; 2023; 10.1007/s10876-023-02497-6
• Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review Cite
  Asnaashari S, Amjad E, Sokouti B. Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review. Cancer Cell International. Springer Science and Business Media LLC; 2023; 23 10.1186/s12935-023-03052-z
• Profiling of phenolic acids, flavonoids, terpenoids, and steroid derivatives in coconut (Cocos nucifera L.) haustorium Cite
  Kim RH, Lee SJ, Lee K, Hwang KT, Kim J. Profiling of phenolic acids, flavonoids, terpenoids, and steroid derivatives in coconut (Cocos nucifera L.) haustorium. Food Science and Biotechnology. Springer Science and Business Media LLC; 2023; 10.1007/s10068-023-01300-6
• Insights on the Role of Polyphenols in Combating Cancer Drug Resistance Cite
  Farhan M. Insights on the Role of Polyphenols in Combating Cancer Drug Resistance. Biomedicines. MDPI AG; 2023; 11:1709 10.3390/biomedicines11061709
• Nanoemulsion Myricetin preparation increases the anticancer efficacy against Triple-negative Breast Cancer cells Cite
  SHARMA P, CHATURVEDI S, KHAN M, RAI Y, Bhatt A, Najmi A, et al. Nanoemulsion Myricetin preparation increases the anticancer efficacy against Triple-negative Breast Cancer cells. Authorea, Inc.; 2023; 10.22541/au.167939853.32039231/v1
• Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities Cite
  Holland TM, Agarwal P, Wang Y, Dhana K, Leurgans SE, Shea K, et al. Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities. Neurology. Ovid Technologies (Wolters Kluwer Health); 2022;:10.1212/WNL.0000000000201541 10.1212/wnl.0000000000201541
• Myricetin: targeting signaling networks in cancer and its implication in chemotherapy Cite
  Javed Z, Khan K, Herrera-Bravo J, Naeem S, Iqbal MJ, Raza Q, et al. Myricetin: targeting signaling networks in cancer and its implication in chemotherapy. Cancer Cell International. Springer Science and Business Media LLC; 2022; 22 10.1186/s12935-022-02663-2
• The Anti-Cancer Effects of Red-Pigmented Foods: Biomarker Modulation and Mechanisms Underlying Cancer Progression Cite
  Chung M, Hwang J, Lee J, Choi H. The Anti-Cancer Effects of Red-Pigmented Foods: Biomarker Modulation and Mechanisms Underlying Cancer Progression. Applied Sciences. MDPI AG; 2022; 12:2584 10.3390/app12052584
• Myricetin induces apoptosis through the MAPK pathway and regulates JNK‑mediated autophagy in SK‑BR‑3 cells Cite
  Han S, Lee J, Woo J, Jung G, Jung S, Han E, et al. Myricetin induces apoptosis through the MAPK pathway and regulates JNK‑mediated autophagy in SK‑BR‑3 cells. International Journal of Molecular Medicine. Spandidos Publications; 2022; 49 10.3892/ijmm.2022.5110
• Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics Cite
  Meerson A, Khatib S, Mahajna J. Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics. International Journal of Molecular Sciences. MDPI AG; 2021; 22:13044 10.3390/ijms222313044
• Myricetin inhibits breast and lung cancer cells proliferation via inhibiting MARK4 Cite
  Anwar S, Khan S, Anjum F, Shamsi A, Khan P, Fatima H, et al. Myricetin inhibits breast and lung cancer cells proliferation via inhibiting MARK4. Journal of Cellular Biochemistry. Wiley; 2021; 10.1002/jcb.30176
• Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA Cite
  Gacche RN. Role of Dietary Ingredients on Expression of Oncogenic and Tumour Suppressor miRNA. Dietary Research and Cancer. Springer Singapore; 2021;:69-76 10.1007/978-981-16-6050-4_7
• Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice Cite
  Hassan SM, Khalaf MM, Sadek SA, Abo-Youssef AM. Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice. Pharmaceutical Biology. Informa UK Limited; 2017; 55:766-774 10.1080/13880209.2016.1275704
• Myricetin: A comprehensive review on its biological potentials Cite
  Imran M, Saeed F, Hussain G, Imran A, Mehmood Z, Gondal TA, et al. Myricetin: A comprehensive review on its biological potentials. Food Science & Nutrition. Wiley; 2021; 10.1002/fsn3.2513
• Myricetin: A review of the most recent research Cite
  Song X, Tan L, Wang M, Ren C, Guo C, Yang B, et al. Myricetin: A review of the most recent research. Biomedicine & Pharmacotherapy. Elsevier BV; 2020; 134:111017 10.1016/j.biopha.2020.111017
• Flavonoids in Cancer Metastasis Cite
  Liskova A, Koklesova L, Samec M, Smejkal K, Samuel SM, Varghese E, et al. Flavonoids in Cancer Metastasis. Cancers. MDPI AG; 2020; 12:1498 10.3390/cancers12061498
• Myricetin induces apoptosis mediated by oxidative stress in 4T1 and E0771 mammary cancer cells Cite
  Knickle A, Rasmussen A, Hoskin DW. Myricetin induces apoptosis mediated by oxidative stress in 4T1 and E0771 mammary cancer cells. Molecular & Cellular Toxicology. Springer Science and Business Media LLC; 2020; 16:283-289 10.1007/s13273-020-00089-3
• Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China Cite
  Feng X, Ho SC, Mo X, Lin F, Zhang N, Luo H, et al. Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2019; 29:493-500 10.1097/cej.0000000000000561
• Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide Cite
  Knickle A, Fernando W, Greenshields AL, Rupasinghe HV, Hoskin DW. Myricetin-induced apoptosis of triple-negative breast cancer cells is mediated by the iron-dependent generation of reactive oxygen species from hydrogen peroxide. Food and Chemical Toxicology. Elsevier BV; 2018; 118:154-167 10.1016/j.fct.2018.05.005
• Evaluation of protective effect of myricetin, a bioflavonoid in dimethyl benzanthracene-induced breast cancer in female Wistar rats Cite
  Jayakumar J, Nirmala P, Praveen Kumar B, Kumar A. Evaluation of protective effect of myricetin, a bioflavonoid in dimethyl benzanthracene-induced breast cancer in female Wistar rats. South Asian Journal of Cancer. Georg Thieme Verlag KG; 2014; 3:107 10.4103/2278-330x.130443
• Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9 Cite
  Ci Y, Zhang Y, Liu Y, Lu S, Cao J, Li H, et al. Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9. Phytotherapy Research. Wiley; 2018; 32:1373-1381 10.1002/ptr.6071
• Myricetin Inhibits Angiogenesis by Inducing Apoptosis and Suppressing PI3K/Akt/mTOR Signaling in Endothelial Cells Cite
  Kim GD. Myricetin Inhibits Angiogenesis by Inducing Apoptosis and Suppressing PI3K/Akt/mTOR Signaling in Endothelial Cells. Journal of Cancer Prevention. Korean Society of Cancer Prevention; 2017; 22:219-227 10.15430/jcp.2017.22.4.219
• Enhanced oral bioavailability of docetaxel in rats combined with myricetin: In situ and in vivo evidences Cite
  Hao T, Ling Y, Wu M, Shen Y, Gao Y, Liang S, et al. Enhanced oral bioavailability of docetaxel in rats combined with myricetin: In situ and in vivo evidences. European Journal of Pharmaceutical Sciences. Elsevier BV; 2017; 101:71-79 10.1016/j.ejps.2017.02.009
• Myricetin arrests human telomeric G-quadruplex structure: a new mechanistic approach as an anticancer agent Cite
  Mondal S, Jana J, Sengupta P, Jana S, Chatterjee S. Myricetin arrests human telomeric G-quadruplex structure: a new mechanistic approach as an anticancer agent. Molecular BioSystems. Royal Society of Chemistry (RSC); 2016; 12:2506-2518 10.1039/c6mb00218h
• Myricetin suppresses p21-activated kinase 1 in human breast cancer MCF-7 cells through downstream signaling of the β-catenin pathway Cite
  JIAO D, ZHANG XD. Myricetin suppresses p21-activated kinase 1 in human breast cancer MCF-7 cells through downstream signaling of the β-catenin pathway. Oncology Reports. Spandidos Publications; 2016; 36:342-348 10.3892/or.2016.4777
• Myricetin: biological activity related to human health Cite
  Park K, Chong Y, Kim MK. Myricetin: biological activity related to human health. Applied Biological Chemistry. Springer Science and Business Media LLC; 2016; 59:259-269 10.1007/s13765-016-0150-2
• Myricetin induces apoptosis and enhances chemosensitivity in ovarian cancer cells Cite
  Zheng A, Chen Y, Zhao L, Feng J. Myricetin induces apoptosis and enhances chemosensitivity in ovarian cancer cells. Oncology Letters. Spandidos Publications; 2017; 13:4974-4978 10.3892/ol.2017.6031
• Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2) Cite
  Tan KW, Li Y, Paxton JW, Birch NP, Scheepens A. Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2). Food Chemistry. Elsevier BV; 2013; 138:2267-2274 10.1016/j.foodchem.2012.12.021
• Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin Cite
  Choi S, Shin S, Choi J. Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin. Archives of Pharmacal Research. Springer Science and Business Media LLC; 2011; 34:309-315 10.1007/s12272-011-0217-x
• Influence of Domestic Processing and Storage on Flavonol Contents in Berries Cite
  Häkkinen SH, Kärenlampi SO, Mykkänen HM, Törrönen AR. Influence of Domestic Processing and Storage on Flavonol Contents in Berries. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2000; 48:2960-2965 10.1021/jf991274c