Tag: doxorubicinAdriamycin

Articles

• Exercise and breast cancer survival
• Factors influencing Adriamycin (doxorubicin) effectiveness
• Foods to eat and avoid during Adriamycin chemotherapy
• Fruit and Adriamycin chemotherapy for breast cancer

News

03/23/25

Cherry anthocyanins potentiate Adriamycin in triple negative cells

04/22/24

EGFR inhibition enhances treatment effects of Adriamycin

10/04/21

Melatonin enhances the treatment effects of Adriamycin in breast cancer cells

01/25/21

Ursolic acid enhances Adriamycin treatment in TN breast cancer

06/12/19

Resveratrol increases effectiveness of Adriamycin chemotherapy

05/06/19

Metformin reduces resistance to Adriamycin chemotherapy

04/21/18

Quercetin can reverse chemotherapy resistance in ER+/PR+ BC cells

03/11/18

Flaxseed lignans increase treatment effects of Adriamycin & Taxotere

09/26/17

Black cumin enhances Adriamycin toxicity and reduces cardiomyopathy

08/09/16

Quercetin could interfere with Adriamycin treatment

04/08/16

Genistein could reduce treatment effects of Adriamycin in ER+/PR+ BC

09/19/15

Ferritin can protect breast cancer cells from treatment by Adriamycin

06/16/13

Resveratrol enhances the effectiveness of Adriamycin in ER+/PR+ cells

05/31/13

Black pepper compound increases effectiveness of Taxol in HER2+ BC

10/14/12

Fatty fish compound DHA increases Adriamycin efficacy in TN cells

05/30/12

Fish oil might promote Adriamycin-induced heart damage

02/15/12

Grapes might help protect against Adriamycin-induced heart damage

12/15/11

Kaempferol protects against Adriamycin-induced heart damage

12/07/11

Modern chemotherapy reduces BC death by about a third

12/01/11

Herceptin + anthracycline chemo increases risk of cardiomyopathy

11/09/11

Curcumin reduces breast cancer resistance to Adriamycin

09/24/11

Caffeine may reduce the effectiveness of Adriamycin chemotherapy

07/11/11

Taking Celebrex might reduce effectiveness of chemotherapy

11/03/10

Chemotherapy resistance is accompanied by more BC stem cells

Studies

• Enhanced antitumour efficacy of ferulic acid nanoparticles in combination with doxorubicin – a promising strategy for breast cancer treatment Cite
  Salama AF, Omran G, Salahuddin AM, Abd-El-Azim HM, Noreldin A, M. Okda T. Enhanced antitumour efficacy of ferulic acid nanoparticles in combination with doxorubicin – a promising strategy for breast cancer treatment. Współczesna Onkologia. Termedia Sp. z.o.o.; 2025; 10.5114/wo.2025.151917
• Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions Cite
  Ali MA, Kaleem N, Ali A, Khan N, Khaliq M, Arif N, et al. Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions. Medical Oncology. Springer Science and Business Media LLC; 2025; 42 10.1007/s12032-025-02721-5
• Anticancer efficacy of dual-loaded SLNs with Doxorubicin (DOX) and Pterostilbene (PTS): formulation, characterization, and evaluation for breast cancer Cite
  Marwah H, Pant J, Shah K, Alam P, Dewangan HK. Anticancer efficacy of dual-loaded SLNs with Doxorubicin (DOX) and Pterostilbene (PTS): formulation, characterization, and evaluation for breast cancer. Nanomedicine. Informa UK Limited; 2025; 20:1249-1265 10.1080/17435889.2025.2501526
• Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin Cite
  Milliana A, Sari RA, Miranda SA, Mutiah R. Evaluation of Anticancer Activity and Mechanism of Action of Myricetin on HeLa, T47D, and Vero Cells: Comparative Analysis with Cisplatin and Doxorubicin. Biomedical and Pharmacology Journal. Oriental Scientific Publishing Company; 2025; 18:835-847 10.13005/bpj/3133
• Astragalus Injection Modulates the Pharmacokinetics of Doxorubicin and CYP450 Enzymes Cite
  Shi W, Liu T, Wang K, Mu L, Ji L, Li Y, et al. Astragalus Injection Modulates the Pharmacokinetics of Doxorubicin and CYP450 Enzymes. Current Pharmaceutical Design. Bentham Science Publishers Ltd.; 2025; 31 10.2174/0113816128362829250527023843
• Exploring the effects of exercise on immune cell function and tumour infiltration in patients with breast cancer receiving neoadjuvant chemotherapy – a feasibility trial Cite
  Ubink A, ten Tusscher MR, van der Vliet HJ, Douma JA, de Gruijl TD, Bontkes H, et al. Exploring the effects of exercise on immune cell function and tumour infiltration in patients with breast cancer receiving neoadjuvant chemotherapy – a feasibility trial. Brain, Behavior, & Immunity - Health. Elsevier BV; 2025; 46:101021 10.1016/j.bbih.2025.101021
• Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial Cite
  Munhoz J, Newell M, Goruk S, Ghosh S, Patel D, Joy AA, et al. Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial. Breast Cancer Research. Springer Science and Business Media LLC; 2025; 27 10.1186/s13058-025-02048-z
• Abstract 4240: Combining belinostat with red grape seed extract effectively inhibits cell proliferation, induces apoptosis, and reduces tumor resistance to doxorubicin by targeting mutant KRAS and p-ERK in human breast cancer Cite
  Kerema MS, Deghedy SH, Khalil S, Sultan AS. Abstract 4240: Combining belinostat with red grape seed extract effectively inhibits cell proliferation, induces apoptosis, and reduces tumor resistance to doxorubicin by targeting mutant KRAS and p-ERK in human breast cancer. Cancer Research. American Association for Cancer Research (AACR); 2025; 85:4240-4240 10.1158/1538-7445.am2025-4240
• Dark Sweet Cherry (Prunus avium L.) Juice Phenolics Rich in Anthocyanins Exhibit Potential to Inhibit Drug Resistance Mechanisms in 4T1 Breast Cancer Cells via the Drug Metabolism Pathway Cite
  Nava-Ochoa A, Mertens-Talcott SU, Talcott ST, Noratto GD. Dark Sweet Cherry (Prunus avium L.) Juice Phenolics Rich in Anthocyanins Exhibit Potential to Inhibit Drug Resistance Mechanisms in 4T1 Breast Cancer Cells via the Drug Metabolism Pathway. Current Issues in Molecular Biology. MDPI AG; 2025; 47:213 10.3390/cimb47030213
• Omega-3 fatty acids: molecular weapons against chemoresistance in breast cancer Cite
  Marchio V, Augimeri G, Morelli C, Vivacqua A, Giordano C, Catalano S, et al. Omega-3 fatty acids: molecular weapons against chemoresistance in breast cancer. Cellular & Molecular Biology Letters. Springer Science and Business Media LLC; 2025; 30 10.1186/s11658-025-00694-x
• Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export Cite
  Choi H, Gupta M, Sengupta A, Furth EE, Hensley C, Weljie AM, et al. Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export. Neoplasia. Elsevier BV; 2025; 61:101136 10.1016/j.neo.2025.101136
• Cardioprotective effect of crocin in patients with breast cancer receiving anthracycline-based chemotherapy: A randomized, double-blind, placebo-controlled study Cite
  Li X, Su X, Liang W, Wang L, Yuan C, Xu J, et al. Cardioprotective effect of crocin in patients with breast cancer receiving anthracycline-based chemotherapy: A randomized, double-blind, placebo-controlled study. Pharmacological Research. Elsevier BV; 2025; 213:107630 10.1016/j.phrs.2025.107630
• In Silico and In Vitro Verification of the Effects of Chemotherapeutic Doxorubicin and 5‐Fluorouracil in Combination With Curcumin and Vitamin C on MCF‐7 Cells Cite
  Akyüz A, Şirin DY. In Silico and In Vitro Verification of the Effects of Chemotherapeutic Doxorubicin and 5‐Fluorouracil in Combination With Curcumin and Vitamin C on MCF‐7 Cells. Journal of Cellular Biochemistry. Wiley; 2024; 10.1002/jcb.30688
• FRUCTOSE EXACERBATES ANTHRACYCLINE AND HER-2 BLOCKING AGENT MEDIATED CARDIOTOXICITY THROUGH NLRP3 AND MYD88 MEDIATED PATHWAYS: NEW ROLES OF SWEETENERS IN CARDIO-ONCOLOGY Cite
  Maurea N, bisceglia i, Iovine M, Giordano V, GIACOBBE I, Arianna R, et al. FRUCTOSE EXACERBATES ANTHRACYCLINE AND HER-2 BLOCKING AGENT MEDIATED CARDIOTOXICITY THROUGH NLRP3 AND MYD88 MEDIATED PATHWAYS: NEW ROLES OF SWEETENERS IN CARDIO-ONCOLOGY. Journal of the American College of Cardiology. Elsevier BV; 2024; 83:2563 10.1016/s0735-1097(24)04553-4
• CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity Cite
  Liu C, Shen M, Liu Y, Manhas A, Zhao SR, Zhang M, et al. CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. Cell Stem Cell. Elsevier BV; 2024; 31:1760-1776.e9 10.1016/j.stem.2024.10.007
• Zerumbone And Doxorubicin Combination Induces MAPK3 Dependent Apoptosis in Triple Negative Breast Cancer Cells Cite
  Mehraj U, Sofi S, Wani NA, Mir MA. Zerumbone And Doxorubicin Combination Induces MAPK3 Dependent Apoptosis in Triple Negative Breast Cancer Cells. Springer Science and Business Media LLC; 2024; 10.21203/rs.3.rs-5457453/v1
• Cyclophosphamide- and doxorubicin-induced impairment of high affinity choline uptake and spatial memory can be prevented by dietary choline supplementation in breast tumor bearing mice Cite
  Botelho R, Kirstein CL, Philpot RM. Cyclophosphamide- and doxorubicin-induced impairment of high affinity choline uptake and spatial memory can be prevented by dietary choline supplementation in breast tumor bearing mice. PLOS ONE. Public Library of Science (PLoS); 2024; 19:e0305365 10.1371/journal.pone.0305365
• The Effect of High-Intensity Interval Training on Quality of Life and Incidence of Chemotherapy Side Effects in Women With Breast Cancer Cite
  Klavina A, Ceseiko R, Campa M, Jermolenko GF, Eglitis K, Llorente A, et al. The Effect of High-Intensity Interval Training on Quality of Life and Incidence of Chemotherapy Side Effects in Women With Breast Cancer. Integrative Cancer Therapies. SAGE Publications; 2024; 23 10.1177/15347354241297385
• Abstract 4147821: Physical Activity Impacts Cardiac Tissue Mitochondrial Respiration During Anthracycline Chemotherapy Cite
  Riojas A, Harbert S, Lacy J, Piloso J, Kramer P, Weis J, et al. Abstract 4147821: Physical Activity Impacts Cardiac Tissue Mitochondrial Respiration During Anthracycline Chemotherapy. Circulation. Ovid Technologies (Wolters Kluwer Health); 2024; 150 10.1161/circ.150.suppl_1.4147821
• Tyrosine kinase inhibitors versus thymoquinone in management of cancer: A mechanistic approach Cite
  Nath SK, Garg M, Babbar R. Tyrosine kinase inhibitors versus thymoquinone in management of cancer: A mechanistic approach. AIP Conference Proceedings. AIP Publishing; 2024; 3232:060014 10.1063/5.0227771
• Melatonin mitigates doxorubicin induced chemo brain in a rat model in a NRF2/p53–SIRT1 dependent pathway Cite
  Ebrahim NA, Elnagar MR, El-Gamal R, Habotta OA, Albadawi EA, Albadrani M, et al. Melatonin mitigates doxorubicin induced chemo brain in a rat model in a NRF2/p53–SIRT1 dependent pathway. Heliyon. Elsevier BV; 2024; 10:e38081 10.1016/j.heliyon.2024.e38081
• Effects of exercise therapy on chemotherapy delivery and response in primary breast cancer: A secondary analysis of a randomized trial Cite
  Iyengar NM, Scott JM, Lee J, Lavery JA, Foug KL, Lee CP, et al. Effects of exercise therapy on chemotherapy delivery and response in primary breast cancer: A secondary analysis of a randomized trial. Cancer. Wiley; 2024; 10.1002/cncr.35575
• Dark Sweet Cherry Phenolics Enriched in Anthocyanins Suppressed Breast Cancer Lung Metastasis, Inhibited Tumor Growth, and Enhanced Doxorubicin Anticancer Activity In Vivo Cite
  Nava-Ochoa AE, Noratto G, Talcott S. Dark Sweet Cherry Phenolics Enriched in Anthocyanins Suppressed Breast Cancer Lung Metastasis, Inhibited Tumor Growth, and Enhanced Doxorubicin Anticancer Activity In Vivo. Current Developments in Nutrition. Elsevier BV; 2024; 8:102589 10.1016/j.cdnut.2024.102589
• Systemic Codelivery of Thymoquinone and Doxorubicin by Targeted Mesoporous Silica Nanoparticle Sensitizes Doxorubicin-Resistant Breast Cancer by Interfering between the MDR1/P-gp and miR 298 Crosstalk Cite
  Bhattacharjee M, Ghosh A, Das S, Sarker S, Bhattacharya S, Das A, et al. Systemic Codelivery of Thymoquinone and Doxorubicin by Targeted Mesoporous Silica Nanoparticle Sensitizes Doxorubicin-Resistant Breast Cancer by Interfering between the MDR1/P-gp and miR 298 Crosstalk. ACS Biomaterials Science & Engineering. American Chemical Society (ACS); 2024; 10.1021/acsbiomaterials.4c01081
• Low Sucrose Diets Protect Long-Term Memory and EPA & DHA Enriched Diets Alter Insulin Resistance in a Mouse Model of Chemotherapy Cite
  Ormiston K, Fitzgerald J, Andridge R, Lustberg MB, DeVries AC, Orchard TS. Low Sucrose Diets Protect Long-Term Memory and EPA & DHA Enriched Diets Alter Insulin Resistance in a Mouse Model of Chemotherapy. Nutrition Research. Elsevier BV; 2024; 10.1016/j.nutres.2024.09.004
• The protective effect of nano curcumin supplementation on doxorubicin induced cardiotoxicity in breast cancer patients; a randomized, double-blind clinical trial Cite
  Tohidi M, Allahyari A, Ataei Azimi S, Alimi H, Elyasi S, Qoorchi Moheb Seraj F, et al. The protective effect of nano curcumin supplementation on doxorubicin induced cardiotoxicity in breast cancer patients; a randomized, double-blind clinical trial. Journal of Oncology Pharmacy Practice. SAGE Publications; 2024; 10.1177/10781552241277958
• Continuous exposure to doxorubicin induces stem cell-like characteristics and plasticity in MDA-MB-231 breast cancer cells identified with the SORE6 reporter Cite
  Salinas-Jazmín N, Medina-Mondragón MA, Jiménez-López J, Guerrero-Rodríguez SL, Cuautle-Rodríguez P, Velasco-Velázquez MA. Continuous exposure to doxorubicin induces stem cell-like characteristics and plasticity in MDA-MB-231 breast cancer cells identified with the SORE6 reporter. Cancer Chemotherapy and Pharmacology. Springer Science and Business Media LLC; 2024; 10.1007/s00280-024-04701-4
• Combination of resveratrol and piperine to target doxorubicin resistance in breast cancer: An in vitro and in vivo study Cite
  AlHur MJ, Barakova N, Talib WH. Combination of resveratrol and piperine to target doxorubicin resistance in breast cancer: An in vitro and in vivo study. Pharmacia. Pensoft Publishers; 2024; 71:1-10 10.3897/pharmacia.71.e122171
• Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells Cite
  Hakeem AN, El-Kersh DM, Hammam O, Elhosseiny A, Zaki A, Kamel K, et al. Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells. Scientific Reports. Springer Science and Business Media LLC; 2024; 14 10.1038/s41598-024-65508-0
• Therapeutic Applications of Rosmarinic Acid in Cancer-Chemotherapy-Associated Resistance and Toxicity Cite
  Villegas C, Cortez N, Ogundele AV, Burgos V, Pardi PC, Cabrera-Pardo JR, et al. Therapeutic Applications of Rosmarinic Acid in Cancer-Chemotherapy-Associated Resistance and Toxicity. Biomolecules. MDPI AG; 2024; 14:867 10.3390/biom14070867
• Possible protective effect of rosuvastatin in chemotherapy-induced cardiotoxicity in HER2 positive breast cancer patients: a randomized controlled trial Cite
  Kettana KM, El‑Haggar SM, Alm El-Din MA, El‑Afify DR. Possible protective effect of rosuvastatin in chemotherapy-induced cardiotoxicity in HER2 positive breast cancer patients: a randomized controlled trial. Medical Oncology. Springer Science and Business Media LLC; 2024; 41 10.1007/s12032-024-02426-1
• Outcomes of older adults with early-stage triple-negative breast cancer (TNBC) receiving chemotherapy: a single-institution experience Cite
  Singareeka Raghavendra A, Liu D, Shen Y, Barcenas CH, Ueno NT, Giordano S, et al. Outcomes of older adults with early-stage triple-negative breast cancer (TNBC) receiving chemotherapy: a single-institution experience. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2024; 10.1007/s10549-024-07309-7
• The combination of Curcumin and Doxorubicin on targeting PI3K/AKT/mTOR signaling pathway: an in vitro and molecular docking study for inhibiting the survival of MDA-MB-231 Cite
  Sarkar E, Kotiya A, Khan A, Bhuyan R, Raza ST, Misra A, et al. The combination of Curcumin and Doxorubicin on targeting PI3K/AKT/mTOR signaling pathway: an in vitro and molecular docking study for inhibiting the survival of MDA-MB-231. In Silico Pharmacology. Springer Science and Business Media LLC; 2024; 12 10.1007/s40203-024-00231-2
• Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma Cite
  Neppelenbroek SI, Geurts YM, Aleman BM, Lugtenburg PJ, Rademakers SE, de Weijer RJ, et al. Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2024; 42:1903-1913 10.1200/jco.23.01386
• Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis Cite
  Bucci T, Gue Y, Dobson R, Palmieri C, Pignatelli P, Lip GYH. Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis. Clinical and Experimental Medicine. Springer Science and Business Media LLC; 2024; 24 10.1007/s10238-024-01395-z
• Exosome-sheathed porous silica nanoparticle-mediated co-delivery of 3,3′-diindolylmethane and doxorubicin attenuates cancer stem cell-driven EMT in triple negative breast cancer Cite
  Sarkar R, Biswas S, Ghosh R, Samanta P, Pakhira S, Mondal M, et al. Exosome-sheathed porous silica nanoparticle-mediated co-delivery of 3,3′-diindolylmethane and doxorubicin attenuates cancer stem cell-driven EMT in triple negative breast cancer. Journal of Nanobiotechnology. Springer Science and Business Media LLC; 2024; 22 10.1186/s12951-024-02518-0
• Potential of Natural Phenolic Compounds against Doxorubicin-Induced Chemobrain: Biological and Molecular Mechanisms Involved Cite
  Serini S, Calviello G. Potential of Natural Phenolic Compounds against Doxorubicin-Induced Chemobrain: Biological and Molecular Mechanisms Involved. Antioxidants. MDPI AG; 2024; 13:486 10.3390/antiox13040486
• Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects Cite
  Mirzadeh MA, Eslami M, Ghanbari A, Zarbakhsh S, Yosefi S, Pakdel A. Coadministration of doxorubicin with vitamin D3, Lactobacillus acidophilus, and Lactobacillus casei in the 4T1 mouse model of breast cancer: anticancer and enteroprotective effects. Medical Oncology. Springer Science and Business Media LLC; 2024; 41 10.1007/s12032-024-02346-0
• The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity Cite
  Helvacioglu S, Charehsaz M, Bankoglu EE, Stopper H, Aydin A. The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity. Drug and Chemical Toxicology. Informa UK Limited; 2024;:1-13 10.1080/01480545.2024.2332790
• Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect Cite
  Zhu L, Yang K, Ren Z, Yin D, Zhou Y. Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect. Translational Oncology. Elsevier BV; 2024; 44:101945 10.1016/j.tranon.2024.101945
• Epidermal growth factor receptor inhibition potentiates chemotherapeutics‐mediated sensitization of metastatic breast cancer stem cells Cite
  Kar T, Dugam P, Shivhare S, Shetty SR, Choudhury S, Sen D, et al. Epidermal growth factor receptor inhibition potentiates chemotherapeutics‐mediated sensitization of metastatic breast cancer stem cells. Cancer Reports. Wiley; 2024; 7 10.1002/cnr2.2049
• Rhein potentiates doxorubicin in treating triple negative breast cancer by inhibiting cancer-associated fibroblasts Cite
  Xu S, Zheng S, Ma N, Zhang H, Shi J, Huang J, et al. Rhein potentiates doxorubicin in treating triple negative breast cancer by inhibiting cancer-associated fibroblasts. Biochemical Pharmacology. Elsevier BV; 2024;:116139 10.1016/j.bcp.2024.116139
• Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway Cite
  Chen H, Zhou J, Fong SY. Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway. Pakistan Journal of Zoology. ResearchersLinks Ltd; 2024; 56 10.17582/journal.pjz/20220421100442
• Thymoquinone Nanoparticle Induces Apoptosis and Cell Migration Retardation through Modulating of SUMOylation Process Genes in Breast Cancer Cell Line Cite
  Sabouni F, Hamta A, Sohrabi B, Qadbeigi M. Thymoquinone Nanoparticle Induces Apoptosis and Cell Migration Retardation through Modulating of SUMOylation Process Genes in Breast Cancer Cell Line. Iranian Journal of Biotechnology. National Institute of Genetic Engineering and Biotechnology of Iran; 2024; 22 10.30498/ijb.2024.390400.3676
• Allicin Overcomes Doxorubicin Resistance of Breast Cancer Cells by Targeting the Nrf2 Pathway Cite
  Shi G, Li X, Wang W, Hou L, Yin L, Wang L. Allicin Overcomes Doxorubicin Resistance of Breast Cancer Cells by Targeting the Nrf2 Pathway. Cell Biochemistry and Biophysics. Springer Science and Business Media LLC; 2024; 10.1007/s12013-024-01215-x
• The efficacy and safety of exercise regimens to mitigate chemotherapy cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials Cite
  Amin AM, Khlidj Y, Abuelazm M, Ibrahim AA, Tanashat M, Imran M, et al. The efficacy and safety of exercise regimens to mitigate chemotherapy cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials. Cardio-Oncology. Springer Science and Business Media LLC; 2024; 10 10.1186/s40959-024-00208-2
• Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma Cite
  Neppelenbroek SI, Geurts YM, Aleman BM, Lugtenburg PJ, Rademakers SE, de Weijer RJ, et al. Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2024; 10.1200/jco.23.01386
• Effect of quercetin on doxorubicin cytotoxicity in sensitive and resistant human MCF7 breast cancer cell lines Cite
  Almohammad Aljabr B, Zihlif M, Abu‑Dahab R, Zalloum H. Effect of quercetin on doxorubicin cytotoxicity in sensitive and resistant human MCF7 breast cancer cell lines. Biomedical Reports. Spandidos Publications; 2024; 20 10.3892/br.2024.1745
• Antitumoral and chemoprotective evaluation of isolated Bromelain and in combination with Doxorubicin Cite
  Sousa AA, Nobre TA, Martins JA, Miranda KL, Avelino YS, Pereira ARS, et al. Antitumoral and chemoprotective evaluation of isolated Bromelain and in combination with Doxorubicin. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3569568/v1
• Wnt3a/GSK3β/β-catenin Signalling Modulates Doxorubicin-associated Memory Deficits in Breast Cancer Cite
  Li W, Gan C, Yu S, Xu J, Tang L, Cheng H. Wnt3a/GSK3β/β-catenin Signalling Modulates Doxorubicin-associated Memory Deficits in Breast Cancer. Molecular Neurobiology. Springer Science and Business Media LLC; 2024; 10.1007/s12035-023-03910-x
• Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review Cite
  Sailo BL, Liu L, Chauhan S, Girisa S, Hegde M, Liang L, et al. Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review. Cancers. MDPI AG; 2024; 16:244 10.3390/cancers16020244
• PP171 Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in chemosensitivity of cytotoxic drugs Cite
  Parmar HS. PP171 Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in chemosensitivity of cytotoxic drugs. ESMO Open. Elsevier BV; 2023; 8:102166 10.1016/j.esmoop.2023.102166
• Dietary approaches for exploiting metabolic vulnerabilities in cancer Cite
  Menyhárt O, Győrffy B. Dietary approaches for exploiting metabolic vulnerabilities in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. Elsevier BV; 2023;:189062 10.1016/j.bbcan.2023.189062
• Diosmin alleviates Doxorubicin-induced chemobrain in rats via inhibition of oxido-inflammation, apoptosis and modulation of autophagy Cite
  Mega OO, Faith FY, Ejiro OP, Uchechukwu JG, Temitope OG, Oghenetega OB, et al. Diosmin alleviates Doxorubicin-induced chemobrain in rats via inhibition of oxido-inflammation, apoptosis and modulation of autophagy. Brain Disorders. Elsevier BV; 2023;:100111 10.1016/j.dscb.2023.100111
• Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer Cite
  Sudhakaran M, Navarrete TG, Mejía-Guerra K, Mukundi E, Eubank TD, Grotewold E, et al. Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer. Cell Death & Disease. Springer Science and Business Media LLC; 2023; 14 10.1038/s41419-023-06342-6
• Effectiveness of Nigella sativa Addition against TNF-Alpha in Stage III and IV Breast Cancer Undergoing Doxorubicin and Cyclophosphamide Chemotherapy at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Cite
  Friyoga Syahril , Wirdah A, Nur Qodir , Irfanuddin , Irsan Saleh , Yenny Dian Andayani , et al. Effectiveness of Nigella sativa Addition against TNF-Alpha in Stage III and IV Breast Cancer Undergoing Doxorubicin and Cyclophosphamide Chemotherapy at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Bioscientia Medicina : Journal of Biomedicine and Translational Research. Hanif Medisiana Publisher; 2023; 8:4009-4014 10.37275/bsm.v8i2.924
• Statin use is associated with a lower risk of mortality in patients with malignant breast cancer treated with anthracyclines. A global federated health database analysis Cite
  Bucci T, Gue Y, Dobson R, Palmieri C, Pignatelli P, Cross M, et al. Statin use is associated with a lower risk of mortality in patients with malignant breast cancer treated with anthracyclines. A global federated health database analysis. European Heart Journal. Oxford University Press (OUP); 2023; 44 10.1093/eurheartj/ehad655.2876
• Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer Cite
  Wang Y, Ronckers CM, van Leeuwen FE, Moskowitz CS, Leisenring W, Armstrong GT, et al. Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer. Nature Medicine. Springer Science and Business Media LLC; 2023; 29:2268-2277 10.1038/s41591-023-02514-1
• Protective effect of grape seed extract and exercise training on tissues toxicities in doxorubicin-treated healthy rat Cite
  Belhadjali F, Ghrir S, Ksia F, Limam F, Aouani E, Mokni M. Protective effect of grape seed extract and exercise training on tissues toxicities in doxorubicin-treated healthy rat. Biomarkers. Informa UK Limited; 2023;:1-11 10.1080/1354750x.2023.2246698
• Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer Cite
  Shakiba E, Bazi A, Ghasemi H, Eshaghi‐Gorji R, Mehdipour SA, Nikfar B, et al. Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer. Journal of Cellular and Molecular Medicine. Wiley; 2023; 10.1111/jcmm.17902
• Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions Cite
  Liu C, Chen H, Guo S, Liu Q, Chen Z, Huang H, et al. Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 166:115373 10.1016/j.biopha.2023.115373
• Racial Disparity in Anthracycline-induced Cardiotoxicity in Breast Cancer Patients Cite
  Balaji S, Antony AK, Tonchev H, Scichilone G, Morsy M, Deen H, et al. Racial Disparity in Anthracycline-induced Cardiotoxicity in Breast Cancer Patients. Biomedicines. MDPI AG; 2023; 11:2286 10.3390/biomedicines11082286
• Assessment of thyme honey oral gel for the prevention of adriamycin and cyclophosphamide chemotherapy-induced oral mucositis in patients with breast cancer Cite
  Jahanbani Mazraeh E, Sadighi S, Manifar S, Bakhshandeh H, Rajabi M. Assessment of thyme honey oral gel for the prevention of adriamycin and cyclophosphamide chemotherapy-induced oral mucositis in patients with breast cancer. Supportive Care in Cancer. Springer Science and Business Media LLC; 2023; 31 10.1007/s00520-023-07943-9
• Metabolomics Analysis Reveals Altered Metabolic Pathways and Response to Doxorubicin in Drug-Resistant Triple-Negative Breast Cancer Cells Cite
  Rushing BR, Molina S, Sumner S. Metabolomics Analysis Reveals Altered Metabolic Pathways and Response to Doxorubicin in Drug-Resistant Triple-Negative Breast Cancer Cells. Metabolites. MDPI AG; 2023; 13:865 10.3390/metabo13070865
• Synergism of Curcumin and Doxorubicin Proves an Effective Anticancer Therapeutics Against Breast Cancer: An in vitro Study Cite
  Sarkar E, Khan A, Ahmad R, Misra A, Dua K, Mahdi AA, et al. Synergism of Curcumin and Doxorubicin Proves an Effective Anticancer Therapeutics Against Breast Cancer: An in vitro Study. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3147856/v1
• A comprehensive review of the health benefits of flaxseed oil in relation to its chemical composition and comparison with other omega-3-rich oils Cite
  Al-Madhagy S, Ashmawy NS, Mamdouh A, Eldahshan OA, Farag MA. A comprehensive review of the health benefits of flaxseed oil in relation to its chemical composition and comparison with other omega-3-rich oils. European Journal of Medical Research. Springer Science and Business Media LLC; 2023; 28 10.1186/s40001-023-01203-6
• Short-term fasting and fasting mimicking diets combined with chemotherapy: a narrative review Cite
  Kikomeko J, Schutte T, van Velzen MJ, Seefat R, van Laarhoven HW. Short-term fasting and fasting mimicking diets combined with chemotherapy: a narrative review. Therapeutic Advances in Medical Oncology. SAGE Publications; 2023; 15:175883592311614 10.1177/17588359231161418
• Bovine milk‐derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling Cite
  Sanwlani R, Kang T, Gummadi S, Nedeva C, Ang C, Mathivanan S. Bovine milk‐derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling. PROTEOMICS. Wiley; 2023; 10.1002/pmic.202200482
• Human Papillomavirus maybe is a critical player in the Regulation of Chemoresistance related Factors (P53, Rb, TWIST, Bcl-2, Bcl-XL, c-IAP2, cytochrome C, and caspase 3) in Breast Cancer Cite
  Haghighi ZMS, Tabatabaei T, Rafigh M, Karampour R, Babaei F, Amjad ZS, et al. Human Papillomavirus maybe is a critical player in the Regulation of Chemoresistance related Factors (P53, Rb, TWIST, Bcl-2, Bcl-XL, c-IAP2, cytochrome C, and caspase 3) in Breast Cancer. Pathology - Research and Practice. Elsevier BV; 2023;:154653 10.1016/j.prp.2023.154653
• Does insulin make breast cancer cells resistant to doxorubicin toxicity? Cite
  Lykhova O, Zavelevich M, Philchenkov A, Vidasov N, Kozak T, Lozovska Y, et al. Does insulin make breast cancer cells resistant to doxorubicin toxicity?. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2023; 10.1007/s00210-023-02516-3
• Redefining the “crown”: Approaching chemotherapy‐induced alopecia among Black patients with breast cancer Cite
  Pleasant VA, Purkiss AS, Merjaver SD. Redefining the “crown”: Approaching chemotherapy‐induced alopecia among Black patients with breast cancer. Cancer. Wiley; 2023; 129:1629-1633 10.1002/cncr.34732
• Crocin-loaded liposomes sensitize MDA-MB 231 breast cancer cells to doxorubicin by inducing apoptosis Cite
  Chavoshi H, Taheri M, Wan MLY, Sabzichi M. Crocin-loaded liposomes sensitize MDA-MB 231 breast cancer cells to doxorubicin by inducing apoptosis. Process Biochemistry. Elsevier BV; 2023; 10.1016/j.procbio.2023.04.012
• Alpha-Lipoic Acid Ameliorates Doxorubicin-Induced Cognitive Impairments by Modulating Neuroinflammation and Oxidative Stress via NRF-2/HO-1 Signaling Pathway in the Rat Hippocampus Cite
  Lal R, Dharavath RN, Chopra K. Alpha-Lipoic Acid Ameliorates Doxorubicin-Induced Cognitive Impairments by Modulating Neuroinflammation and Oxidative Stress via NRF-2/HO-1 Signaling Pathway in the Rat Hippocampus. Neurochemical Research. Springer Science and Business Media LLC; 2023; 10.1007/s11064-023-03914-y
• Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway Cite
  Liang L, Zhao L, Yu B, Hu H, He X, Zhang Y. Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway. The Kaohsiung Journal of Medical Sciences. Wiley; 2023; 10.1002/kjm2.12675
• The Effect of the Synergistic Combination of Vitamin D and Doxorubicin on the MCF-7 Line Breast Cancer Cells Cite
  Sobczak K, Mlicka A, Niewiadomski P, Abramczyk O, Zielińska W, Hałas-Wiśniewska M, et al. The Effect of the Synergistic Combination of Vitamin D and Doxorubicin on the MCF-7 Line Breast Cancer Cells. Cells 2023. MDPI; 2023; 10.3390/blsf2023021020
• Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model Cite
  Pogorzelska A, Mazur M, Świtalska M, Wietrzyk J, Sigorski D, Fronczyk K, et al. Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 161:114490 10.1016/j.biopha.2023.114490
• Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming Cite
  Pateras IS, Williams C, Gianniou DD, Margetis AT, Avgeris M, Rousakis P, et al. Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming. Journal of Translational Medicine. Springer Science and Business Media LLC; 2023; 21 10.1186/s12967-023-03935-9
• Metabolomics Analysis Reveals Novel Targets of Chemosensitizing Polyphenols and Omega-3 Polyunsaturated Fatty Acids in Triple Negative Breast Cancer Cells Cite
  Rushing BR, Wiggs A, Molina S, Schroder M, Sumner S. Metabolomics Analysis Reveals Novel Targets of Chemosensitizing Polyphenols and Omega-3 Polyunsaturated Fatty Acids in Triple Negative Breast Cancer Cells. International Journal of Molecular Sciences. MDPI AG; 2023; 24:4406 10.3390/ijms24054406
• Combinatorial Assessment of Doxorubicin with Chlorogenic acid by in silico studies and development of its polymeric-nanoparticle against breast cancer Cite
  Jindal D, Sinha S, Agarwal V, Sisodia V, Singh M. Combinatorial Assessment of Doxorubicin with Chlorogenic acid by in silico studies and development of its polymeric-nanoparticle against breast cancer. Materials Today: Proceedings. Elsevier BV; 2023; 10.1016/j.matpr.2023.02.131
• Mechanism of Saffron Extract against Cardiotoxicity Induced by Doxorubicin: 4D Label-Free Quantitative proteomics Analysis and Bioinformatic Study Cite
  Sa R, Lin Z, Huang J, Wang Y, Lv J, Zhang X, et al. Mechanism of Saffron Extract against Cardiotoxicity Induced by Doxorubicin: 4D Label-Free Quantitative proteomics Analysis and Bioinformatic Study. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2580481/v1
• Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010 Cite
  Larsen CM, Garcia Arango M, Dasari H, Arciniegas Calle M, Adjei E, Rico Mesa J, et al. Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010. JAMA Network Open. American Medical Association (AMA); 2023; 6:e2254669 10.1001/jamanetworkopen.2022.54669
• Quercetin Effects on Cell Cycle Arrest and Apoptosis and Doxorubicin Activity in T47D Cancer Stem Cells Cite
  Azizi E, Fouladdel S, Komeili Movahhed T, Modaresi F, Barzegar E, Ghahremani MH, et al. Quercetin Effects on Cell Cycle Arrest and Apoptosis and Doxorubicin Activity in T47D Cancer Stem Cells. Asian Pacific Journal of Cancer Prevention. EpiSmart Science Vector Ltd; 2022; 23:4145-4154 10.31557/apjcp.2022.23.12.4145
• A review of the pharmacodynamic effect of chemo-herbal drug combinations therapy for cancer treatment Cite
  Okem A, Henstra C, Lambert M, Hayeshi R. A review of the pharmacodynamic effect of chemo-herbal drug combinations therapy for cancer treatment. Medicine in Drug Discovery. Elsevier BV; 2023; 17:100147 10.1016/j.medidd.2022.100147
• The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2—A Systematic Review Cite
  Krejbich P, Birringer M. The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2—A Systematic Review. Antioxidants. MDPI AG; 2022; 11:2149 10.3390/antiox11112149
• The anti-proliferative effect of β-carotene against a triple-negative breast cancer cell line is cancer cell-specific and JNK-dependent Cite
  Antunes A, Carmo F, Pinto S, Andrade N, Martel F. The anti-proliferative effect of β-carotene against a triple-negative breast cancer cell line is cancer cell-specific and JNK-dependent. PharmaNutrition. Elsevier BV; 2022; 22:100320 10.1016/j.phanu.2022.100320
• pH-responsive co-delivery of Doxorubicin and Saffron via Cross-linked Chitosan/Laponite RD Nanoparticles for Enhanced-Chemotherapy Cite
  Heragh BK, Taherinezhad H, Mahdavinia GR, Javanshir S, Labib P, Ghasemsolb S. pH-responsive co-delivery of Doxorubicin and Saffron via Cross-linked Chitosan/Laponite RD Nanoparticles for Enhanced-Chemotherapy. Materials Today Communications. Elsevier BV; 2022;:104956 10.1016/j.mtcomm.2022.104956
• Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction Cite
  Luo F, Zhao J, Liu S, Xue Y, Tang D, Yang J, et al. Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction. Biochemical Pharmacology. Elsevier BV; 2022; 205:115278 10.1016/j.bcp.2022.115278
• Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro Cite
  Khajah MA, Khushaish S, Luqmani YA. Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro. PLOS ONE. Public Library of Science (PLoS); 2022; 17:e0272449 10.1371/journal.pone.0272449
• Cardioprotective effects of Ferulic acid against various drugs and toxic agents Cite
  Pandi A, Raghu MH, Chandrashekar N, Kalappan VM. Cardioprotective effects of Ferulic acid against various drugs and toxic agents. Beni-Suef University Journal of Basic and Applied Sciences. Springer Science and Business Media LLC; 2022; 11 10.1186/s43088-022-00273-5
• Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells Cite
  O’Grady S, Crown J, Duffy MJ. Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells. Medical Oncology. Springer Science and Business Media LLC; 2022; 39 10.1007/s12032-022-01733-9
• Apigenin alleviates resistance to doxorubicin in breast cancer cells by acting on the JAK/STAT signaling pathway Cite
  Maashi MS, Al-Mualm M, Al-Awsi GRL, Opulencia MJC, Al-Gazally ME, Abdullaev B, et al. Apigenin alleviates resistance to doxorubicin in breast cancer cells by acting on the JAK/STAT signaling pathway. Molecular Biology Reports. Springer Science and Business Media LLC; 2022; 10.1007/s11033-022-07727-0
• In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin Cite
  Shadyro O, Sosnovskaya A, Edimecheva I, Ihnatovich L, Dubovik B, Krasny S, et al. In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin. Frontiers in Pharmacology. Frontiers Media SA; 2022; 13 10.3389/fphar.2022.882197
• Vitamin D status in breast cancer cases following chemotherapy: A pre and post observational study in a tertiary hospital in Yogyakarta, Indonesia Cite
  Puspitaningtyas H, Sulistyoningrum DC, Witaningrum R, Widodo I, Hardianti MS, Taroeno-Hariadi KW, et al. Vitamin D status in breast cancer cases following chemotherapy: A pre and post observational study in a tertiary hospital in Yogyakarta, Indonesia. PLOS ONE. Public Library of Science (PLoS); 2022; 17:e0270507 10.1371/journal.pone.0270507
• Synergistic effects of natural compounds and conventional chemotherapeutic agents: recent insights for the development of cancer treatment strategies Cite
  Castañeda AM, Meléndez CM, Uribe D, Pedroza-Díaz J. Synergistic effects of natural compounds and conventional chemotherapeutic agents: recent insights for the development of cancer treatment strategies. Heliyon. Elsevier BV; 2022; 8:e09519 10.1016/j.heliyon.2022.e09519
• Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients Cite
  Werida RH, Elshafiey RA, Ghoneim A, Elzawawy S, Mostafa TM. Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients. Supportive Care in Cancer. Springer Science and Business Media LLC; 2022; 10.1007/s00520-022-07124-0
• Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats Cite
  Patil C, Wagh S, Patil K, Mahajan U, Bagal P, Wadkar A, et al. Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats. Asian Pacific Journal of Tropical Biomedicine. Medknow; 2022; 12:124 10.4103/2221-1691.338921
• Melatonin as an adjuvant treatment modality with doxorubicin Cite
  Dana PM, Sadoughi F, Reiter RJ, Mohammadi S, Heidar Z, Mirzamoradi M, et al. Melatonin as an adjuvant treatment modality with doxorubicin. Biochimie. Elsevier BV; 2022; 10.1016/j.biochi.2022.05.005
• Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice Cite
  Eekhoudt CR, Bortoluzzi T, Varghese SS, Cheung DYC, Christie S, Eastman S, et al. Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice. Current Oncology. MDPI AG; 2022; 29:2941-2953 10.3390/curroncol29050241
• Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways Cite
  Li S, Liu H, Lin Z, Li Z, Chen Y, Chen B, et al. Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways. Phytomedicine. Elsevier BV; 2022; 101:154105 10.1016/j.phymed.2022.154105
• Synergistic anti-cancer effects of Nigella sativa seed oil and conventional cytotoxic agent against human breast cancer Cite
  Baig WA, Alwosaibai K, Al-Jubran KM, Chaudhry TM, Al-Dowish N, Alsaffar F, et al. Synergistic anti-cancer effects of Nigella sativa seed oil and conventional cytotoxic agent against human breast cancer. Drug Metabolism and Personalized Therapy. Walter de Gruyter GmbH; 2022; 0 10.1515/dmpt-2021-0229
• Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study Cite
  Greenlee H, Iribarren C, Rana JS, Cheng R, Nguyen-Huynh M, Rillamas-Sun E, et al. Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2022; 10.1200/jco.21.01736
• Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation Cite
  Li D, Liu X, Pi W, Zhang Y, Yu L, Xu C, et al. Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation. Frontiers in Pharmacology. Frontiers Media SA; 2022; 12 10.3389/fphar.2021.808480
• Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection Cite
  Adham AN, Abdelfatah S, Naqishbandi A, Sugimoto Y, Fleischer E, Efferth T. Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection. Phytomedicine. Elsevier BV; 2022; 100:154064 10.1016/j.phymed.2022.154064
• Natural Polysaccharide β-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress Cite
  Wang X, Ji Y, Jin D, Qi J, Hou X, Zhao W, et al. Natural Polysaccharide β-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress. Nutrients. MDPI AG; 2022; 14:906 10.3390/nu14040906
• Inhibitory Effect of Ursolic Acid on the Migration and Invasion of Doxorubicin-Resistant Breast Cancer Cite
  Zong L, Cheng G, Zhao J, Zhuang X, Zheng Z, Liu Z, et al. Inhibitory Effect of Ursolic Acid on the Migration and Invasion of Doxorubicin-Resistant Breast Cancer. Molecules. MDPI AG; 2022; 27:1282 10.3390/molecules27041282
• Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients? Cite
  Lagunas-Rangel FA, Liu W, Schiöth HB. Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?. International Journal of Environmental Research and Public Health. MDPI AG; 2022; 19:2064 10.3390/ijerph19042064
• Lupeol synergizes with doxorubicin to induce anti-proliferative and apoptotic effects on breast cancer cells Cite
  Malekinejad F, Kheradmand F, Khadem-Ansari MH, Malekinejad H. Lupeol synergizes with doxorubicin to induce anti-proliferative and apoptotic effects on breast cancer cells. DARU Journal of Pharmaceutical Sciences. Springer Science and Business Media LLC; 2022; 10.1007/s40199-022-00436-w
• Prevention of doxorubicin-induced experimental cardiotoxicity by Nigella sativa in rats Cite
  Adıyaman MŞ, Adıyaman ÖA, Dağlı AF, Karahan MZ, Dağlı MN. Prevention of doxorubicin-induced experimental cardiotoxicity by Nigella sativa in rats. Revista Portuguesa de Cardiologia. Elsevier BV; 2022; 10.1016/j.repc.2020.12.015
• Kaempferol attenuates doxorubicin-mediated nephropathy in rats by activating SIRT1 signaling Cite
  Alagal RI, AlFaris NA, Alshammari GM, ALTamimi JZ, AlMousa LA, Yahya MA. Kaempferol attenuates doxorubicin-mediated nephropathy in rats by activating SIRT1 signaling. Journal of Functional Foods. Elsevier BV; 2022; 89:104918 10.1016/j.jff.2021.104918
• Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents Cite
  Farooq J, Sultana R, Taj T, Asdaq SMB, Alsalman AJ, Mohaini MA, et al. Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents. Molecules. MDPI AG; 2021; 27:226 10.3390/molecules27010226
• Overexpression of Neuron-Derived Orphan Receptor 1 (NOR-1) Rescues Cardiomyocytes from Cell Death and Improves Viability after Doxorubicin Induced Stress Cite
  Berg P, Hansson ÅML, Røsand Ø, Marwarha G, Høydal MA. Overexpression of Neuron-Derived Orphan Receptor 1 (NOR-1) Rescues Cardiomyocytes from Cell Death and Improves Viability after Doxorubicin Induced Stress. Biomedicines. MDPI AG; 2021; 9:1233 10.3390/biomedicines9091233
• Coenzyme Q10 protects against doxorubicin-induced cardiomyopathy via antioxidant and anti-apoptotic pathway Cite
  Shabaan DA, Mostafa N, El-Desoky MM, Arafat EA. Coenzyme Q10 protects against doxorubicin-induced cardiomyopathy via antioxidant and anti-apoptotic pathway. Tissue Barriers. Informa UK Limited; 2021; 10.1080/21688370.2021.2019504
• Caffeic acid phenethyl ester protects against doxorubicin-induced cardiotoxicity and increases chemotherapeutic efficacy by regulating the unfolded protein response Cite
  Zhang Y, Kong D, Han H, Cao Y, Zhu H, Cui G. Caffeic acid phenethyl ester protects against doxorubicin-induced cardiotoxicity and increases chemotherapeutic efficacy by regulating the unfolded protein response. Food and Chemical Toxicology. Elsevier BV; 2022; 159:112770 10.1016/j.fct.2021.112770
• Quercetin Alleviates the Immunotoxic Impact Mediated by Oxidative Stress and Inflammation Induced by Doxorubicin Exposure in Rats Cite
  Farag MR, Moselhy AAA, El-Mleeh A, Aljuaydi SH, Ismail TA, Di Cerbo A, et al. Quercetin Alleviates the Immunotoxic Impact Mediated by Oxidative Stress and Inflammation Induced by Doxorubicin Exposure in Rats. Antioxidants. MDPI AG; 2021; 10:1906 10.3390/antiox10121906
• Quercetin Enhances the Suppressive Effects of Doxorubicin on the Migration of MDA-MB-231 Breast Cancer Cell Line Cite
  Roshanazadeh M, Babaahmadi Rezaei H, Rashidi M. Quercetin Enhances the Suppressive Effects of Doxorubicin on the Migration of MDA-MB-231 Breast Cancer Cell Line. International Journal of Cancer Management. Briefland; 2021; 14 10.5812/ijcm.119049
• DEHP mediates drug resistance by directly targeting AhR in human breast cancer Cite
  Hsieh T, Hsu C, Yang P, Chiu C, Liang S, Ou-Yang F, et al. DEHP mediates drug resistance by directly targeting AhR in human breast cancer. Biomedicine & Pharmacotherapy. Elsevier BV; 2022; 145:112400 10.1016/j.biopha.2021.112400
• Curcumin Ameliorates Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity Via Suppressing Oxidative Stress and Modulating iNOS, NF-κB, and TNF-α in Rats Cite
  Ibrahim Fouad G, Ahmed KA. Curcumin Ameliorates Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity Via Suppressing Oxidative Stress and Modulating iNOS, NF-κB, and TNF-α in Rats. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2021; 10.1007/s12012-021-09710-w
• Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Cite
  Wakefield ZR, Tanaka M, Pampo C, Lepler S, Rice L, Guingab-Cagmat J, et al. Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice. Oncotarget. Impact Journals, LLC; 2021; 12:1737-1748 10.18632/oncotarget.28057
• Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy Cite
  Ormiston K, Gaudier-Diaz MM, TinKai T, Fitzgerald J, Cole RM, Andridge R, et al. Effects of plant-based versus marine-based omega-3 fatty acids and sucrose on brain and liver fatty acids in a mouse model of chemotherapy. Nutritional Neuroscience. Informa UK Limited; 2021;:1-9 10.1080/1028415x.2021.1998296
• Revisiting the Anticancer Drug–Food Interactions Cite
  Gacche RN. Revisiting the Anticancer Drug–Food Interactions. Dietary Research and Cancer. Springer Singapore; 2021;:113-120 10.1007/978-981-16-6050-4_11
• The diuretic amiloride attenuates doxorubicin-induced chemobrain in rats: Behavioral and mechanistic study Cite
  Ali AE, Elsherbiny DM, Azab SS, El-Demerdash E. The diuretic amiloride attenuates doxorubicin-induced chemobrain in rats: Behavioral and mechanistic study. NeuroToxicology. Elsevier BV; 2021; 10.1016/j.neuro.2021.10.002
• Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors Cite
  Varghese SS, Johnston WJ, Eekhoudt CR, Keats MR, Jassal DS, Grandy SA. Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors. Current Oncology. MDPI AG; 2021; 28:4139-4156 10.3390/curroncol28050351
• Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity Cite
  Waz S, Matouk AI. Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity. Toxicology Mechanisms and Methods. Informa UK Limited; 2021;:1-25 10.1080/15376516.2021.1992064
• The beneficial efficacy of liposomal resveratrol against doxorubicin-induced hepatotoxicity in rats: Role of TGF-β1 and SIRT1 Cite
  Alhusaini AM, Alanazi AM, Fadda LM, Alqahtani QH, Sarawi WS, Hasan IH. The beneficial efficacy of liposomal resveratrol against doxorubicin-induced hepatotoxicity in rats: Role of TGF-β1 and SIRT1. Journal of King Saud University - Science. Elsevier BV; 2021;:101640 10.1016/j.jksus.2021.101640
• A careful reassessment of anthracycline use in curable breast cancer Cite
  Hurvitz SA, McAndrew NP, Bardia A, Press MF, Pegram M, Crown JP, et al. A careful reassessment of anthracycline use in curable breast cancer. npj Breast Cancer. Springer Science and Business Media LLC; 2021; 7 10.1038/s41523-021-00342-5
• Thymoquinone upregulates miR‐125a‐5p, attenuates STAT3 activation, and potentiates doxorubicin antitumor activity in murine solid Ehrlich carcinoma Cite
  Atteia HH, Arafa MH, Mohammad NS, Amin DM, Sakr AT. Thymoquinone upregulates miR‐125a‐5p, attenuates STAT3 activation, and potentiates doxorubicin antitumor activity in murine solid Ehrlich carcinoma. Journal of Biochemical and Molecular Toxicology. Wiley; 2021; 10.1002/jbt.22924
• The Potential protective role of astaxanthin on doxorubicin-induced cardiac toxicity in rats Cite
  Derias MSM, Sabaa AERFA, Osman AEMMA, Mohamed AEA, Abou-bakr Darwish DA. The Potential protective role of astaxanthin on doxorubicin-induced cardiac toxicity in rats. QJM: An International Journal of Medicine. Oxford University Press (OUP); 2021; 114 10.1093/qjmed/hcab117.003
• Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells Cite
  Tran QH, Hoang DH, Song M, Choe W, Kang I, Kim SS, et al. Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells. Experimental & Molecular Medicine. Springer Science and Business Media LLC; 2021; 10.1038/s12276-021-00675-y
• Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating Nuclear factor - like 2 and Sirtuin 2 signaling pathways Cite
  Deng J, Huang M, Wu H. Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating Nuclear factor - like 2 and Sirtuin 2 signaling pathways. Bioengineered. Informa UK Limited; 2021; 10.1080/21655979.2021.1985299
• Pharmacodynamics Interaction of Quercetin and Captopril on Doxorubicin Induced Myocardial Toxic Rats Cite
  . Pharmacodynamics Interaction of Quercetin and Captopril on Doxorubicin Induced Myocardial Toxic Rats. Biointerface Research in Applied Chemistry. AMG Transcend Association; 2021; 12:3002-3011 10.33263/briac123.30023011
• 188P Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy of breast cancer: A double blind, randomized clinical trial Cite
  Javadinia S, Salek R, Dehghani M, Mohajeri S, Talaei A, Fanipakdel A. 188P Amelioration of anxiety, depression, and chemotherapy related toxicity after crocin administration during chemotherapy of breast cancer: A double blind, randomized clinical trial. Annals of Oncology. Elsevier BV; 2021; 32:S439-S440 10.1016/j.annonc.2021.08.469
• Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats Cite
  Patel P, Shah J. Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats. Life Sciences. Elsevier BV; 2021; 285:119957 10.1016/j.lfs.2021.119957
• Atorvastatin facilitates chemotherapy effects in metastatic triple-negative breast cancer Cite
  Marti JLG, Beckwitt CH, Clark AM, Wells A. Atorvastatin facilitates chemotherapy effects in metastatic triple-negative breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2021; 10.1038/s41416-021-01529-0
• Nanonutraceuticals: Anti-Cancer Activity and Improved Safety of Chemotherapy by Costunolide and Its Nanoformulation against Colon and Breast Cancer Cite
  El-Far AH, Godugu K, Salaheldin TA, Darwish NHE, Saddiq AA, Mousa SA. Nanonutraceuticals: Anti-Cancer Activity and Improved Safety of Chemotherapy by Costunolide and Its Nanoformulation against Colon and Breast Cancer. Biomedicines. MDPI AG; 2021; 9:990 10.3390/biomedicines9080990
• Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats Cite
  Abdulkareem Aljumaily SA, Demir M, Elbe H, Yigitturk G, Bicer Y, Altinoz E. Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats. Environmental Science and Pollution Research. Springer Science and Business Media LLC; 2021; 10.1007/s11356-021-15409-w
• Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo Cite
  Tang S, Kan J, Sun R, Cai H, Hong J, Jin C, et al. Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo. Journal of Food Biochemistry. Wiley; 2021; 10.1111/jfbc.13869
• Enhanced antitumor activity of doxorubicin by naringenin and metformin in breast carcinoma: an experimental study Cite
  Pateliya B, Burade V, Goswami S. Enhanced antitumor activity of doxorubicin by naringenin and metformin in breast carcinoma: an experimental study. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2021; 10.1007/s00210-021-02104-3
• Cinnamon oil as a co-chemotherapy agent through inhibition of cell migration and MMP-9 expression on 4T1 cells Cite
  Aliyah AN, Lintangsari G, Maran GG, Hermawan A, Meiyanto E. Cinnamon oil as a co-chemotherapy agent through inhibition of cell migration and MMP-9 expression on 4T1 cells. Journal of Complementary and Integrative Medicine. Walter de Gruyter GmbH; 2021; 0 10.1515/jcim-2020-0165
• In Vivo and In Vitro Protective Effects of Rosmarinic Acid against Doxorubicin-Induced Cardiotoxicity Cite
  Rahbardar MG, Eisvand F, Rameshrad M, Razavi BM, Hosseinzadeh H. In Vivo and In Vitro Protective Effects of Rosmarinic Acid against Doxorubicin-Induced Cardiotoxicity. Nutrition and Cancer. Informa UK Limited; 2021;:1-15 10.1080/01635581.2021.1931362
• Antioxidant, anti-inflammatory and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats Cite
  ALJUMAILY SAA, Demir M, Elbe H, Yigitturk G, Bicer Y, Altinoz E. Antioxidant, anti-inflammatory and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats. Research Square Platform LLC; 2021; 10.21203/rs.3.rs-418902/v1
• Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis Cite
  Owumi S, Lewu D, Arunsi U, Oyelere A. Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis. Human & Experimental Toxicology. SAGE Publications; 2021;:096032712110061 10.1177/09603271211006171
• Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase Cite
  Wang CJ, Li D, Danielson JA, Zhang EH, Dong Z, Miller KD, et al. Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase. Cancer Letters. Elsevier BV; 2021; 509:1-12 10.1016/j.canlet.2021.03.026
• Effects of kefir on doxorubicin-induced multidrug resistance in human colorectal cancer cells Cite
  Kim DH, Jeong CH, Cheng WN, Kwon HC, Kim D, Seo K, et al. Effects of kefir on doxorubicin-induced multidrug resistance in human colorectal cancer cells. Journal of Functional Foods. Elsevier BV; 2021; 78:104371 10.1016/j.jff.2021.104371
• Cognitive Impairment Resulting from Treatment with Docetaxel, Doxorubicin, and Cyclophosphamide Cite
  Brown T, McElroy T, Simmons P, Walters H, Ntagwabira F, Wang J, et al. Cognitive Impairment Resulting from Treatment with Docetaxel, Doxorubicin, and Cyclophosphamide. Brain Research. Elsevier BV; 2021;:147397 10.1016/j.brainres.2021.147397
• Resveratrol as Chemosensitizer Agent: State of Art and Future Perspectives Cite
  Cocetta V, Quagliariello V, Fiorica F, Berretta M, Montopoli M. Resveratrol as Chemosensitizer Agent: State of Art and Future Perspectives. International Journal of Molecular Sciences. MDPI AG; 2021; 22:2049 10.3390/ijms22042049
• CAN ANTIOXIDANT VITAMINS AVOID THE DOXORUBICIN CARDIOTOXICITY IN THE BREAST CANCER TREATMENT? Cite
  Lima Cavalcanti ID, Santos Soares JC, de Fátima Ramos dos Santos Medeiros SM, Ferro Cavalcanti IM, de Britto Lira Nogueira MC. CAN ANTIOXIDANT VITAMINS AVOID THE DOXORUBICIN CARDIOTOXICITY IN THE BREAST CANCER TREATMENT?. PharmaNutrition. Elsevier BV; 2021;:100259 10.1016/j.phanu.2021.100259
• Antioxidant and Anti-Inflammatory Effects of Crocin Ameliorate Doxorubicin-Induced Nephrotoxicity in Rats Cite
  Hussain MA, Abogresha NM, AbdelKader G, Hassan R, Abdelaziz EZ, Greish SM. Antioxidant and Anti-Inflammatory Effects of Crocin Ameliorate Doxorubicin-Induced Nephrotoxicity in Rats. Oxidative Medicine and Cellular Longevity. Hindawi Limited; 2021; 2021:1-12 10.1155/2021/8841726
• Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation Cite
  Wu Q, Li W, Zhao J, Sun W, Yang Q, Chen C, et al. Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation. Biomedicine & Pharmacotherapy. Elsevier BV; 2021; 137:111308 10.1016/j.biopha.2021.111308
• Ursolic Acid Enhances Cytotoxicity of Doxorubicin-Resistant Triple-Negative Breast Cancer Cells via ZEB1-AS1/miR-186-5p/ABCC1 Axis Cite
  Lu Q, Chen W, Ji Y, Liu Y, Xue X. Ursolic Acid Enhances Cytotoxicity of Doxorubicin-Resistant Triple-Negative Breast Cancer Cells via ZEB1-AS1/miR-186-5p/ABCC1 Axis. Cancer Biotherapy and Radiopharmaceuticals. Mary Ann Liebert Inc; 2021; 10.1089/cbr.2020.4147
• Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study Cite
  Abdel‐Qadir H, Bobrowski D, Zhou L, Austin PC, Calvillo‐Argüelles O, Amir E, et al. Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study. Journal of the American Heart Association. Ovid Technologies (Wolters Kluwer Health); 2021; 10.1161/jaha.119.018393
• Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage Cite
  Yang G, Song M, Hoang DH, Tran QH, Choe W, Kang I, et al. Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage. Experimental & Molecular Medicine. Springer Science and Business Media LLC; 2020; 10.1038/s12276-020-00541-3
• Impact of Exercise on Chemotherapy Tolerance and Survival in Early-Stage Breast Cancer: A Nonrandomized Controlled Trial Cite
  Kirkham AA, Gelmon KA, Van Patten CL, Bland KA, Wollmann H, McKenzie DC, et al. Impact of Exercise on Chemotherapy Tolerance and Survival in Early-Stage Breast Cancer: A Nonrandomized Controlled Trial. Journal of the National Comprehensive Cancer Network. Harborside Press, LLC; 2020; 18:1670-1677 10.6004/jnccn.2020.7603
• The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy Cite
  Chen M, Gowd V, Wang M, Chen F, Cheng K. The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy. Food & Function. Royal Society of Chemistry (RSC); 2020; 10.1039/d0fo02362k
• Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter Cite
  Singh SV, Chaube B, Mayengbam SS, Singh A, Malvi P, Mohammad N, et al. Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Elsevier BV; 2020;:166011 10.1016/j.bbadis.2020.166011
• Toxicity Reduction and Efficacy Promotion of Doxorubicin in the Treatment of Breast Tumors Assisted by Enhanced Oral Absorption of Curcumin-Loaded Lipid–Polyester Mixed Nanoparticles Cite
  Wang N, Zhang Y, Liu H, Wang A, Ren T, Gou J, et al. Toxicity Reduction and Efficacy Promotion of Doxorubicin in the Treatment of Breast Tumors Assisted by Enhanced Oral Absorption of Curcumin-Loaded Lipid–Polyester Mixed Nanoparticles. Molecular Pharmaceutics. American Chemical Society (ACS); 2020; 17:4533-4547 10.1021/acs.molpharmaceut.0c00718
• Kaempferol protects mitochondria and alleviates damages against endotheliotoxicity induced by doxorubicin Cite
  Wu W, Yang B, Qiao Y, Zhou Q, He H, He M. Kaempferol protects mitochondria and alleviates damages against endotheliotoxicity induced by doxorubicin. Biomedicine & Pharmacotherapy. Elsevier BV; 2020; 126:110040 10.1016/j.biopha.2020.110040
• The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy Cite
  Chen M, Gowd V, Wang M, Chen F, Cheng K. The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy. Food & Function. Royal Society of Chemistry (RSC); 2021; 12:177-190 10.1039/d0fo02362k
• Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor Cite
  Shi J, Li J, Li J, Li R, Wu X, Gao F, et al. Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor. Phytomedicine. Elsevier BV; 2020;:153408 10.1016/j.phymed.2020.153408
• Combining naringenin and metformin with doxorubicin enhances anticancer activity against triple-negative breast cancer in vitro and in vivo Cite
  Pateliya B, Burade V, Goswami S. Combining naringenin and metformin with doxorubicin enhances anticancer activity against triple-negative breast cancer in vitro and in vivo. European Journal of Pharmacology. Elsevier BV; 2020; 891:173725 10.1016/j.ejphar.2020.173725
• Cellular Mechanisms Triggered by the Cotreatment of Resveratrol and Doxorubicin in Breast Cancer: A Translational In Vitro–In Silico Model Cite
  Vargas JE, Puga R, Lenz G, Trindade C, Filippi-Chiela E. Cellular Mechanisms Triggered by the Cotreatment of Resveratrol and Doxorubicin in Breast Cancer: A Translational In Vitro–In Silico Model. Oxidative Medicine and Cellular Longevity. Hindawi Limited; 2020; 2020:1-23 10.1155/2020/5432651
• Doxorubicin and Crocin Co-delivery by Polymeric Nanoparticles for Enhanced Anticancer Potential In Vitro and In Vivo Cite
  Khan I, Joshi G, Sarkar B, Nakhate KT, Ajazuddin , Mantha AK, et al. Doxorubicin and Crocin Co-delivery by Polymeric Nanoparticles for Enhanced Anticancer Potential In Vitro and In Vivo. ACS Applied Bio Materials. American Chemical Society (ACS); 2020; 3:7789-7799 10.1021/acsabm.0c00974
• Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation Cite
  Ali MA, Menze ET, Tadros MG, Tolba MF. Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation. Neuropharmacology. Elsevier BV; 2020; 181:108334 10.1016/j.neuropharm.2020.108334
• Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters Cite
  Sudhakaran M, Parra MR, Stoub H, Gallo KA, Doseff AI. Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters. Biochemical Pharmacology. Elsevier BV; 2020; 182:114259 10.1016/j.bcp.2020.114259
• Risk of heart failure after systemic treatment for early breast cancer: results of a cohort study Cite
  Jacobse JN, Schaapveld M, Boekel NB, Hooning MJ, Jager A, Baaijens MHA, et al. Risk of heart failure after systemic treatment for early breast cancer: results of a cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 10.1007/s10549-020-05930-w
• Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner Cite
  Yu W, Qin X, Zhang Y, Qiu P, Wang L, Zha W, et al. Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner. Cardiovascular Diagnosis and Therapy. AME Publishing Company; 2020; 10:752-769 10.21037/cdt-19-707
• Nutritional supplements in combination with chemotherapy or targeted therapy reduces tumor progression in mice bearing triple-negative breast cancer Cite
  Guo C, Hsia S, Chung C, Lin Y, Shih M, Chen P, et al. Nutritional supplements in combination with chemotherapy or targeted therapy reduces tumor progression in mice bearing triple-negative breast cancer. The Journal of Nutritional Biochemistry. Elsevier BV; 2021; 87:108504 10.1016/j.jnutbio.2020.108504
• Cardioprotective effect of grape polyphenol extract against doxorubicin induced cardiotoxicity Cite
  Sergazy S, Shulgau Z, Fedotovskikh G, Chulenbayeva L, Nurgozhina A, Nurgaziyev M, et al. Cardioprotective effect of grape polyphenol extract against doxorubicin induced cardiotoxicity. Scientific Reports. Springer Science and Business Media LLC; 2020; 10 10.1038/s41598-020-71827-9
• Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells Cite
  Rong Y, Huang L, Yi K, Chen H, Liu S, Zhang W, et al. Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells. Cancer Letters. Elsevier BV; 2020; 493:189-196 10.1016/j.canlet.2020.08.041
• The combined effect of creatine and resistance training on doxorubicin-induced muscle dysfunction Cite
  Bredahl EC, Busekrus RB, Hydock DS. The combined effect of creatine and resistance training on doxorubicin-induced muscle dysfunction. Nutrition and Cancer. Informa UK Limited; 2019; 72:939-947 10.1080/01635581.2019.1670852
• Abstract 2965: Aerobic exercise delays intraductal breast cancer growth and suppresses doxorubicin-induced skeletal and cardiac muscle toxicities Cite
  Wakefield Z, Bundy A, Lepler S, Pampo C, Rice L, Siemann D. Abstract 2965: Aerobic exercise delays intraductal breast cancer growth and suppresses doxorubicin-induced skeletal and cardiac muscle toxicities. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2020; 10.1158/1538-7445.am2020-2965
• [10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models Cite
  Baptista Moreno Martin AC, Tomasin R, Luna-Dulcey L, Graminha AE, Araújo Naves M, Teles RHG, et al. [10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models. Cellular Oncology. Springer Science and Business Media LLC; 2020; 43:915-929 10.1007/s13402-020-00539-z
• Fucoidan-Doxorubicin Nanoparticles Targeting P-Selectin for Effective Breast Cancer Therapy Cite
  Jafari M, Sriram V, Xu Z, Harris GM, Lee J. Fucoidan-Doxorubicin Nanoparticles Targeting P-Selectin for Effective Breast Cancer Therapy. Carbohydrate Polymers. Elsevier BV; 2020; 249:116837 10.1016/j.carbpol.2020.116837
• Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma: Role of Notch signaling Cite
  Elsherbiny NM, El-Sherbiny M, Zaitone SA. Diallyl trisulfide potentiates chemotherapeutic efficacy of doxorubicin in experimentally induced mammary carcinoma: Role of Notch signaling. Pathology - Research and Practice. Elsevier BV; 2020; 216:153139 10.1016/j.prp.2020.153139
• PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades Cite
  Liu D, Ma Z, Xu L, Zhang X, Qiao S, Yuan J. PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades. Aging. Impact Journals, LLC; 2019; 11:10061-10073 10.18632/aging.102418
• The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes Cite
  Eid SY, Althubiti MA, Abdallah ME, Wink M, El-Readi MZ. The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. Phytomedicine. Elsevier BV; 2020; 77:153280 10.1016/j.phymed.2020.153280
• Vitamin D-Induced Molecular Mechanisms to Potentiate Cancer Therapy and to Reverse Drug-Resistance in Cancer Cells Cite
  Negri M, Gentile A, de Angelis C, Montò T, Patalano R, Colao A, et al. Vitamin D-Induced Molecular Mechanisms to Potentiate Cancer Therapy and to Reverse Drug-Resistance in Cancer Cells. Nutrients. MDPI AG; 2020; 12:1798 10.3390/nu12061798
• The Cardioprotective Role of Flaxseed in the Prevention of Doxorubicin- and Trastuzumab-Mediated Cardiotoxicity in C57BL/6 Mice Cite
  Asselin CY, Lam A, Cheung DYC, Eekhoudt CR, Zhu A, Mittal I, et al. The Cardioprotective Role of Flaxseed in the Prevention of Doxorubicin- and Trastuzumab-Mediated Cardiotoxicity in C57BL/6 Mice. The Journal of Nutrition. Oxford University Press (OUP); 2020; 150:2353-2363 10.1093/jn/nxaa144
• Cumulative incidence of chemotherapy-induced cardiotoxicity during a 2-year follow-up period in breast cancer patients Cite
  Cho H, Lee S, Sim SH, Park IH, Lee KS, Kwak MH, et al. Cumulative incidence of chemotherapy-induced cardiotoxicity during a 2-year follow-up period in breast cancer patients. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 182:333-343 10.1007/s10549-020-05703-5
• Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects Cite
  Calcabrini C, Maffei F, Turrini E, Fimognari C. Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects. Frontiers in Pharmacology. Frontiers Media SA; 2020; 11 10.3389/fphar.2020.00567
• Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro Cite
  Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, et al. Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro. International Immunopharmacology. Elsevier BV; 2020; 84:106548 10.1016/j.intimp.2020.106548
• Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles Cite
  Liu S, Li R, Qian J, Sun J, Li G, Shen J, et al. Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles. Molecular Pharmaceutics. American Chemical Society (ACS); 2020; 17:1415-1427 10.1021/acs.molpharmaceut.0c00138
• Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone Cite
  El-Far AH, Darwish NHE, Mousa SA. Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone. Integrative Cancer Therapies. SAGE Publications; 2020; 19:153473541990116 10.1177/1534735419901160
• Exogenous Vitamin C-Triggered Surface Charge Conversion of pH/Reduction-Responsive Micelles for the Enhanced Tumor-Specific Activity of Loaded Doxorubicin Cite
  Wu Z, Chen B, Gan Z, Chen F, Luo X. Exogenous Vitamin C-Triggered Surface Charge Conversion of pH/Reduction-Responsive Micelles for the Enhanced Tumor-Specific Activity of Loaded Doxorubicin. Molecular Pharmaceutics. American Chemical Society (ACS); 2020; 17:954-964 10.1021/acs.molpharmaceut.9b01183
• Exercise Intolerance in Anthracycline‐Treated Breast Cancer Survivors: The Role of Skeletal Muscle Bioenergetics, Oxygenation, and Composition Cite
  Beaudry RI, Kirkham AA, Thompson RB, Grenier JG, Mackey JR, Haykowsky MJ. Exercise Intolerance in Anthracycline‐Treated Breast Cancer Survivors: The Role of Skeletal Muscle Bioenergetics, Oxygenation, and Composition. The Oncologist. Wiley; 2020; 25 10.1634/theoncologist.2019-0777
• Association of body mass index and cardiotoxicity related to anthracyclines and trastuzumab in early breast cancer: French CANTO cohort study Cite
  Kaboré EG, Guenancia C, Vaz-Luis I, Di Meglio A, Pistilli B, Coutant C, et al. Association of body mass index and cardiotoxicity related to anthracyclines and trastuzumab in early breast cancer: French CANTO cohort study. PLOS Medicine. Public Library of Science (PLoS); 2019; 16:e1002989 10.1371/journal.pmed.1002989
• The role of melatonin on doxorubicin-induced cardiotoxicity: A systematic review Cite
  Najafi M, Hooshangi Shayesteh MR, Mortezaee K, Farhood B, Haghi-Aminjan H. The role of melatonin on doxorubicin-induced cardiotoxicity: A systematic review. Life Sciences. Elsevier BV; 2020; 241:117173 10.1016/j.lfs.2019.117173
• Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin Cite
  Delort L, Bougaret L, Cholet J, Vermerie M, Billard H, Decombat C, et al. Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin. Nutrients. MDPI AG; 2019; 11:2839 10.3390/nu11122839
• Doxorubicin and cisplatin induced cognitive impairment: The possible mechanisms and interventions Cite
  Ongnok B, Chattipakorn N, Chattipakorn SC. Doxorubicin and cisplatin induced cognitive impairment: The possible mechanisms and interventions. Experimental Neurology. Elsevier BV; 2020; 324:113118 10.1016/j.expneurol.2019.113118
• Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways Cite
  Zhao Y, Zhang L, Zhao G, Chen Y, Sun K, Wang B. Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways. Journal of Functional Foods. Elsevier BV; 2019; 62:103542 10.1016/j.jff.2019.103542
• Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models Cite
  Gupta P, Srivastava SK. Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models. BMC Medicine. Springer Science and Business Media LLC; 2012; 10 10.1186/1741-7015-10-80
• Coenzyme Q10 Cardioprotective Effects Against Doxorubicin-Induced Cardiotoxicity in Wistar Rat Cite
  Botelho AFM, Lempek MR, Branco SEMT, Nogueira MM, de Almeida ME, Costa AG, et al. Coenzyme Q10 Cardioprotective Effects Against Doxorubicin-Induced Cardiotoxicity in Wistar Rat. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2019; 20:222-234 10.1007/s12012-019-09547-4
• Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p Cite
  Zhang W, Jiang H, Chen Y, Ren F. Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p. Journal of Cellular Biochemistry. Wiley; 2019; 120:16283-16292 10.1002/jcb.28910
• Obesity: an heavyweight player in breast cancer’s chemoresistance Cite
  Vaysse C, Muller C, Fallone F. Obesity: an heavyweight player in breast cancer’s chemoresistance. Oncotarget. Impact Journals, LLC; 2019; 10:3207-3208 10.18632/oncotarget.26905
• Cardioprotective Effect of Marine Astaxanthin on Doxorubicin-Induced Cardiotoxicity in Normal Rats Cite
  AlQahtani AA, Osman AM, Damanhouri ZA, Al-Kreathy HM, Al-Malky HS, Ramadan WS, et al. Cardioprotective Effect of Marine Astaxanthin on Doxorubicin-Induced Cardiotoxicity in Normal Rats. Journal of Pharmaceutical Research International. Sciencedomain International; 2019;:1-11 10.9734/jpri/2019/v27i330170
• Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes Cite
  Marinello PC, Panis C, Silva TNX, Binato R, Abdelhay E, Rodrigues JA, et al. Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes. Scientific Reports. Springer Science and Business Media LLC; 2019; 9 10.1038/s41598-019-42357-w
• Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives Cite
  Ahmed S, Khan H, Fratantonio D, Hasan MM, Sharifi S, Fathi N, et al. Apoptosis induced by luteolin in breast cancer: Mechanistic and therapeutic perspectives. Phytomedicine. Elsevier BV; 2019; 59:152883 10.1016/j.phymed.2019.152883
• Abstract P6-21-05: Concurrent exercise and chemotherapy in preclinical breast cancer models Cite
  Wahlroos S, Wilkinson A, Gallego-Ortega D, Febbraio M, Lim E. Abstract P6-21-05: Concurrent exercise and chemotherapy in preclinical breast cancer models. Poster Session Abstracts. American Association for Cancer Research; 2019; 10.1158/1538-7445.sabcs18-p6-21-05
• Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats Cite
  Aswar U, Mahajan U, Kandhare A, Aswar M. Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2019; 392:659-668 10.1007/s00210-019-01623-4
• Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin Cite
  Sawant AV, Srivastava S, Prassanawar SS, Bhattacharyya B, Panda D. Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin. Biochemical Pharmacology. Elsevier BV; 2019; 163:32-45 10.1016/j.bcp.2019.01.023
• Milk and kefir maintain aspects of health during doxorubicin treatment in rats Cite
  Stewart L, Smoak P, Hydock D, Hayward R, O'Brien K, Lisano J, et al. Milk and kefir maintain aspects of health during doxorubicin treatment in rats. Journal of Dairy Science. American Dairy Science Association; 2019; 102:1910-1917 10.3168/jds.2018-15576
• Rutin Protects against Doxorubicin-Induced Cognitive Dysfunction While Retaining the Anticancer Potential of Dox in a Murine Model of N-Methyl-N-Nitrosourea – Induced Mammary Carcinoma Cite
  Ramalingayya GV, Gourishetti K, Nayak PG, Rao CM, Kishore A, Alnaseer SM, et al. Rutin Protects against Doxorubicin-Induced Cognitive Dysfunction While Retaining the Anticancer Potential of Dox in a Murine Model of N-Methyl-N-Nitrosourea – Induced Mammary Carcinoma. Journal of Environmental Pathology, Toxicology and Oncology. Begell House; 2019; 38:153-163 10.1615/jenvironpatholtoxicoloncol.2019028294
• Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP) Cite
  Lehuédé C, Li X, Dauvillier S, Vaysse C, Franchet C, Clement E, et al. Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP). Breast Cancer Research. Springer Science and Business Media LLC; 2019; 21 10.1186/s13058-018-1088-6
• In the triple-negative breast cancer MDA-MB-231 cell line, sulforaphane enhances the intracellular accumulation and anticancer action of doxorubicin encapsulated in liposomes Cite
  Mielczarek L, Krug P, Mazur M, Milczarek M, Chilmonczyk Z, Wiktorska K. In the triple-negative breast cancer MDA-MB-231 cell line, sulforaphane enhances the intracellular accumulation and anticancer action of doxorubicin encapsulated in liposomes. International Journal of Pharmaceutics. Elsevier BV; 2019; 558:311-318 10.1016/j.ijpharm.2019.01.008
• Codelivery of Adriamycin and P-gp Inhibitor Quercetin Using PEGylated Liposomes to Overcome Cancer Drug Resistance Cite
  Yu J, Chen H, Jiang L, Wang J, Dai J, Wang J. Codelivery of Adriamycin and P-gp Inhibitor Quercetin Using PEGylated Liposomes to Overcome Cancer Drug Resistance. Journal of Pharmaceutical Sciences. Elsevier BV; 2019; 108:1788-1799 10.1016/j.xphs.2018.12.016
• Treatment with DHA Modifies the Response of MDA-MB-231 Breast Cancer Cells and Tumors from nu/nu Mice to Doxorubicin through Apoptosis and Cell Cycle Arrest Cite
  Newell M, Brun M, Field CJ. Treatment with DHA Modifies the Response of MDA-MB-231 Breast Cancer Cells and Tumors from nu/nu Mice to Doxorubicin through Apoptosis and Cell Cycle Arrest. The Journal of Nutrition. Oxford University Press (OUP); 2019; 149:46-56 10.1093/jn/nxy224
• Reversal of multidrug resistance in breast cancer cells by a combination of ursolic acid with doxorubicin Cite
  Zong L, Cheng G, Liu S, Pi Z, Liu Z, Song F. Reversal of multidrug resistance in breast cancer cells by a combination of ursolic acid with doxorubicin. Journal of Pharmaceutical and Biomedical Analysis. Elsevier BV; 2019; 165:268-275 10.1016/j.jpba.2018.11.057
• AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis Cite
  Liu D, Ma Z, Di S, Yang Y, Yang J, Xu L, et al. AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis. Free Radical Biology and Medicine. Elsevier BV; 2018; 129:59-72 10.1016/j.freeradbiomed.2018.08.032
• Naringenin prevents doxorubicin-induced toxicity in kidney tissues by regulating the oxidative and inflammatory insult in Wistar rats Cite
  Khan TH, Ganaie MA, Alharthy KM, Madkhali H, Jan BL, Sheikh IA. Naringenin prevents doxorubicin-induced toxicity in kidney tissues by regulating the oxidative and inflammatory insult in Wistar rats. Archives of Physiology and Biochemistry. Informa UK Limited; 2018; 126:300-307 10.1080/13813455.2018.1529799
• Fabrication of 6-gingerol, doxorubicin and alginate hydroxyapatite into a bio-compatible formulation: enhanced anti-proliferative effect on breast and liver cancer cells Cite
  Manatunga DC, de Silva RM, de Silva KMN, Wijeratne DT, Malavige GN, Williams G. Fabrication of 6-gingerol, doxorubicin and alginate hydroxyapatite into a bio-compatible formulation: enhanced anti-proliferative effect on breast and liver cancer cells. Chemistry Central Journal. Springer Science and Business Media LLC; 2018; 12 10.1186/s13065-018-0482-6
• Wild edible onions — Allium flavum and Allium carinatum — successfully prevent adverse effects of chemotherapeutic drug doxorubicin Cite
  Aleksandar P, Dragana M, Nebojša J, Biljana N, Nataša S, Branka V, et al. Wild edible onions — Allium flavum and Allium carinatum — successfully prevent adverse effects of chemotherapeutic drug doxorubicin. Biomedicine & Pharmacotherapy. Elsevier BV; 2019; 109:2482-2491 10.1016/j.biopha.2018.11.106
• Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells Cite
  Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, et al. Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Life Sciences. Elsevier BV; 2018; 213:149-157 10.1016/j.lfs.2018.10.034
• Fisetin, a plant flavonoid ameliorates doxorubicin-induced cardiotoxicity in experimental rats: the decisive role of caspase-3, COX-II, cTn-I, iNOs and TNF-α Cite
  Ma T, Kandhare AD, Mukherjee-Kandhare AA, Bodhankar SL. Fisetin, a plant flavonoid ameliorates doxorubicin-induced cardiotoxicity in experimental rats: the decisive role of caspase-3, COX-II, cTn-I, iNOs and TNF-α. Molecular Biology Reports. Springer Science and Business Media LLC; 2018; 46:105-118 10.1007/s11033-018-4450-y
• Antiproliferative activity of the combination of doxorubicin/quercetin on MCF7 breast cancer cell line: A combined study using colorimetric assay and synchrotron infrared microspectroscopy Cite
  Elmadany N, Khalil E, Vaccari L, Birarda G, Yousef I, Abu-Dahab R. Antiproliferative activity of the combination of doxorubicin/quercetin on MCF7 breast cancer cell line: A combined study using colorimetric assay and synchrotron infrared microspectroscopy. Infrared Physics & Technology. Elsevier BV; 2018; 95:141-147 10.1016/j.infrared.2018.10.014
• Expression of genes modulated by epigallocatechin-3-gallate in breast cancer cells Cite
  Bogacz A, Wolek M, Juskowiak B, Karasiewicz M, Kamiński A, Uzar I, et al. Expression of genes modulated by epigallocatechin-3-gallate in breast cancer cells. Herba Polonica. Walter de Gruyter GmbH; 2018; 64:31-37 10.2478/hepo-2018-0016
• Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin Cite
  Pawar VK, Singh Y, Sharma K, Shrivastav A, Sharma A, Singh A, et al. Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin. International Journal of Biological Macromolecules. Elsevier BV; 2019; 122:1100-1114 10.1016/j.ijbiomac.2018.09.059
• Silymarin increases the sensitivity of breast cancer cells to doxorubicin in doxorubicin-induced MCF-7 cells by inhibiting breast cancer resistance protein expression Cite
  Permana MY, Soediro TM, Louisa M. Silymarin increases the sensitivity of breast cancer cells to doxorubicin in doxorubicin-induced MCF-7 cells by inhibiting breast cancer resistance protein expression. Journal of Physics: Conference Series. IOP Publishing; 2018; 1073:032055 10.1088/1742-6596/1073/3/032055
• Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity? Cite
  Govender J, Loos B, Marais E, Engelbrecht A. Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?. Toxicology and Applied Pharmacology. Elsevier BV; 2018; 358:86-101 10.1016/j.taap.2018.06.031
• Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells Cite
  Vijay K, Sowmya PR, Arathi BP, Shilpa S, Shwetha HJ, Raju M, et al. Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells. Food and Chemical Toxicology. Elsevier BV; 2018; 118:675-690 10.1016/j.fct.2018.06.027
• Nicotine reduces effectiveness of doxorubicin chemotherapy and promotes CD44+CD24‑ cancer stem cells in MCF‑7 cell populations Cite
  T�rker Şener L, G�ven C, Şener A, Adin �inar S, Solakoğlu S, Albeniz I. Nicotine reduces effectiveness of doxorubicin chemotherapy and promotes CD44+CD24‑ cancer stem cells in MCF‑7 cell populations. Experimental and Therapeutic Medicine. Spandidos Publications; 2018; 10.3892/etm.2018.6149
• Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway Cite
  Hajra S, Patra AR, Basu A, Saha P, Bhattacharya S. Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway. Chemico-Biological Interactions. Elsevier BV; 2018; 290:19-36 10.1016/j.cbi.2018.05.005
• Loading of doxorubicin and thymoquinone with F2 gel nanofibers improves the antitumor activity and ameliorates doxorubicin-associated nephrotoxicity Cite
  Zidan AA, El-Ashmawy NE, Khedr EG, Ebeid EM, Salem ML, Mosalam EM. Loading of doxorubicin and thymoquinone with F2 gel nanofibers improves the antitumor activity and ameliorates doxorubicin-associated nephrotoxicity. Life Sciences. Elsevier BV; 2018; 207:461-470 10.1016/j.lfs.2018.06.008
• Incidence and risk factors for congestive heart failure in patients with early breast cancer who received anthracycline and/or trastuzumab: a big data analysis of the Korean Health Insurance Review and Assessment service database Cite
  Choi JY, Cho EY, Choi YJ, Lee JH, Jung SP, Cho KR, et al. Incidence and risk factors for congestive heart failure in patients with early breast cancer who received anthracycline and/or trastuzumab: a big data analysis of the Korean Health Insurance Review and Assessment service database. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2018; 171:181-188 10.1007/s10549-018-4809-8
• Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation Cite
  Li S, Zhao Q, Wang B, Yuan S, Wang X, Li K. Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation. Phytotherapy Research. Wiley; 2018; 32:1530-1536 10.1002/ptr.6081
• Effect of resveratrol on doxorubicin resistance in breast neoplasm cells by modulating PI3K/Akt signaling pathway Cite
  Chen J, Bai J, Yang K. Effect of resveratrol on doxorubicin resistance in breast neoplasm cells by modulating PI3K/Akt signaling pathway. IUBMB Life. Wiley; 2018; 70:491-500 10.1002/iub.1749
• Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model Cite
  Bose C, Awasthi S, Sharma R, Beneš H, Hauer-Jensen M, Boerma M, et al. Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model. PLOS ONE. Public Library of Science (PLoS); 2018; 13:e0193918 10.1371/journal.pone.0193918
• Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain Cite
  Park H, Kim C, Kwak H, No M, Heo J, Kim T. Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain. Neuropharmacology. Elsevier BV; 2018; 133:451-461 10.1016/j.neuropharm.2018.02.013
• Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin Cite
  Li H, Krstin S, Wang S, Wink M. Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin. Molecules. MDPI AG; 2018; 23:557 10.3390/molecules23030557
• Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity Cite
  Avila MS, Ayub-Ferreira SM, de Barros Wanderley MR, das Dores Cruz F, Gonçalves Brandão SM, Rigaud VOC, et al. Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity. Journal of the American College of Cardiology. Elsevier BV; 2018; 71:2281-2290 10.1016/j.jacc.2018.02.049
• Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3 Cite
  Di Y, De Silva F, Krol ES, Alcorn J. Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3. Nutrition and Cancer. Informa UK Limited; 2018; 70:306-315 10.1080/01635581.2018.1421677
• Quercetin enhances chemotherapeutic effect of doxorubicin against human breast cancer cells while reducing toxic side effects of it Cite
  Li S, Yuan S, Zhao Q, Wang B, Wang X, Li K. Quercetin enhances chemotherapeutic effect of doxorubicin against human breast cancer cells while reducing toxic side effects of it. Biomedicine & Pharmacotherapy. Elsevier BV; 2018; 100:441-447 10.1016/j.biopha.2018.02.055
• Effects of polyphenols on doxorubicin-induced oral keratinocyte cytotoxicity and anticancer potency against oral cancer cells Cite
  Sheng H, Ogawa T, Niwano Y, Sasaki K, Tachibana K. Effects of polyphenols on doxorubicin-induced oral keratinocyte cytotoxicity and anticancer potency against oral cancer cells. Journal of Oral Pathology & Medicine. Wiley; 2018; 47:368-374 10.1111/jop.12685
• Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling Cite
  Ku JM, Hong SH, Kim HI, Lim YS, Lee SJ, Kim M, et al. Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling. European Journal of Inflammation. SAGE Publications; 2018; 16:1721727X1775180 10.1177/1721727x17751809
• Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly- N -acetyl glucosamine nanomatrix in mice bearing solid Ehrlish carcinoma Cite
  El-Ashmawy NE, Khedr EG, Ebeid EM, Salem ML, Zidan AA, Mosalam EM. Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly- N -acetyl glucosamine nanomatrix in mice bearing solid Ehrlish carcinoma. European Journal of Pharmaceutical Sciences. Elsevier BV; 2017; 109:525-532 10.1016/j.ejps.2017.09.012
• Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats Cite
  Rizk HA, Masoud MA, Maher OW. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. Journal of Biochemical and Molecular Toxicology. Wiley; 2017; 31:e21977 10.1002/jbt.21977
• Protective effects of acute exercise prior to doxorubicin on cardiac function of breast cancer patients: A proof-of-concept RCT Cite
  Kirkham A, Shave R, Bland K, Bovard J, Eves N, Gelmon K, et al. Protective effects of acute exercise prior to doxorubicin on cardiac function of breast cancer patients: A proof-of-concept RCT. International Journal of Cardiology. Elsevier BV; 2017; 245:263-270 10.1016/j.ijcard.2017.07.037
• Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway Cite
  El-Ashmawy NE, Khedr NF, El-Bahrawy HA, Abo Mansour HE. Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway. Tumor Biology. SAGE Publications; 2017; 39:101042831769223 10.1177/1010428317692235
• Liposomal curcumin alters chemosensitivity of breast cancer cells to Adriamycin via regulating microRNA expression Cite
  Zhou S, Li J, Xu H, Zhang S, Chen X, Chen W, et al. Liposomal curcumin alters chemosensitivity of breast cancer cells to Adriamycin via regulating microRNA expression. Gene. Elsevier BV; 2017; 622:1-12 10.1016/j.gene.2017.04.026
• Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats Cite
  Ramalingayya GV, Cheruku SP, Nayak P, Kishore A, Shenoy R, Rao CM, et al. Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats. Drug Design, Development and Therapy. Informa UK Limited; 2017; Volume11:1011-1026 10.2147/dddt.s103511
• Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy Cite
  Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, et al. Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy. PLOS Biology. Public Library of Science (PLoS); 2017; 15:e2001951 10.1371/journal.pbio.2001951
• Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis Cite
  Abdel-Qadir H, Ong G, Fazelzad R, Amir E, Lee D, Thavendiranathan P, et al. Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis. Annals of Oncology. Elsevier BV; 2017; 28:628-633 10.1093/annonc/mdw671
• Inhibitory Effect of Fruit Juices on the Doxorubicin Metabolizing Activity of Carbonyl Reductase 1 Cite
  Miura T, Nagai K, Kaneshiro S, Taketomi A, Nakabayashi T, Konishi H, et al. Inhibitory Effect of Fruit Juices on the Doxorubicin Metabolizing Activity of Carbonyl Reductase 1. Drug Metabolism Letters. Bentham Science Publishers Ltd.; 2017; 11 10.2174/1872312811666170309153025
• Ginger extract adjuvant to doxorubicin in mammary carcinoma: study of some molecular mechanisms Cite
  El-Ashmawy NE, Khedr NF, El-Bahrawy HA, Abo Mansour HE. Ginger extract adjuvant to doxorubicin in mammary carcinoma: study of some molecular mechanisms. European Journal of Nutrition. Springer Science and Business Media LLC; 2017; 57:981-989 10.1007/s00394-017-1382-6
• Time-of-Day Dictates Transcriptional Inflammatory Responses to Cytotoxic Chemotherapy Cite
  Borniger JC, Walker II WH, Gaudier-Diaz MM, Stegman CJ, Zhang N, Hollyfield JL, et al. Time-of-Day Dictates Transcriptional Inflammatory Responses to Cytotoxic Chemotherapy. Scientific Reports. Springer Science and Business Media LLC; 2017; 7 10.1038/srep41220
• Rutin attenuates doxorubicin-induced cardiotoxicity via regulating autophagy and apoptosis Cite
  Ma Y, Yang L, Ma J, Lu L, Wang X, Ren J, et al. Rutin attenuates doxorubicin-induced cardiotoxicity via regulating autophagy and apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Elsevier BV; 2017; 1863:1904-1911 10.1016/j.bbadis.2016.12.021
• Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines Cite
  Guerriero E, Sorice A, Capone F, Storti G, Colonna G, Ciliberto G, et al. Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines. International Journal of Oncology. Spandidos Publications; 2017; 50:468-476 10.3892/ijo.2017.3835
• (−)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice Cite
  Yao Y, Liu X, Li W, Shi Z, Yan Y, Wang L, et al. (−)-Epigallocatechin-3-gallate alleviates doxorubicin-induced cardiotoxicity in sarcoma 180 tumor-bearing mice. Life Sciences. Elsevier BV; 2017; 180:151-159 10.1016/j.lfs.2016.12.004
• Effect of crocin and doxorubicin / radiation on the breast cancer cell line, Michigan Cancer Foundation-7 Cite
  Fanayi AR, Changizi V, Safa M. Effect of crocin and doxorubicin / radiation on the breast cancer cell line, Michigan Cancer Foundation-7. Bioscience Biotechnology Research Communications. Society for Science and Nature; 2016; 9:428-434 10.21786/bbrc/9.3/13
• Melissa officinalis Protects against Doxorubicin-Induced Cardiotoxicity in Rats and Potentiates Its Anticancer Activity on MCF-7 Cells Cite
  Hamza AA, Ahmed MM, Elwey HM, Amin A. Melissa officinalis Protects against Doxorubicin-Induced Cardiotoxicity in Rats and Potentiates Its Anticancer Activity on MCF-7 Cells. PLOS ONE. Public Library of Science (PLoS); 2016; 11:e0167049 10.1371/journal.pone.0167049
• Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin Cite
  Ding Y, Peng Y, Deng L, Fan J, Huang B. Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2017; 167:67-77 10.1016/j.jsbmb.2016.11.009
• Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study Cite
  Thamlikitkul L, Srimuninnimit V, Akewanlop C, Ithimakin S, Techawathanawanna S, Korphaisarn K, et al. Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study. Supportive Care in Cancer. Springer Science and Business Media LLC; 2016; 25:459-464 10.1007/s00520-016-3423-8
• P05.03 Morphine enhances doxorubicin uptake in an in vitro model of blood-brain barrier Cite
  Iorio A, da Ros M. P05.03 Morphine enhances doxorubicin uptake in an in vitro model of blood-brain barrier. Neuro-Oncology. Oxford University Press (OUP); 2016; 18:iv27-iv27 10.1093/neuonc/now188.090
• Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line Cite
  Bober P, Alexovic M, Talian I, Tomkova Z, Viscorova Z, Benckova M, et al. Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line. Journal of Cancer Research and Clinical Oncology. Springer Science and Business Media LLC; 2016; 143:35-42 10.1007/s00432-016-2259-4
• Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway Cite
  Huang P, Kuo W, Shen C, Chen Y, Lin Y, Ho T, et al. Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway. International Journal of Molecular Sciences. MDPI AG; 2016; 17:1588 10.3390/ijms17091588
• β-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function Cite
  Teng Y, Sheu M, Hsieh Y, Wang R, Chiang Y, Hung C. β-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function. Phytomedicine. Elsevier BV; 2016; 23:316-323 10.1016/j.phymed.2016.01.008
• Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line Cite
  Bober P, Alexovic M, Talian I, Tomkova Z, Viscorova Z, Benckova M, et al. Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line. Journal of Cancer Research and Clinical Oncology. Springer Science and Business Media LLC; 2016; 143:35-42 10.1007/s00432-016-2259-4
• Obesity As a Risk Factor for Anthracyclines and Trastuzumab Cardiotoxicity in Breast Cancer: A Systematic Review and Meta-Analysis Cite
  Guenancia C, Lefebvre A, Cardinale D, Yu AF, Ladoire S, Ghiringhelli F, et al. Obesity As a Risk Factor for Anthracyclines and Trastuzumab Cardiotoxicity in Breast Cancer: A Systematic Review and Meta-Analysis. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2016; 34:3157-3165 10.1200/jco.2016.67.4846
• Diverse Effects of the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Combination with Tamoxifen Citrate and Doxorubicin in MCF-7 Breast Cancer Cells Cite
  Atay S, Ak H, Kalmis E, Kayalar H, Aydin HH. Diverse Effects of the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Combination with Tamoxifen Citrate and Doxorubicin in MCF-7 Breast Cancer Cells. International Journal of Medicinal Mushrooms. Begell House; 2016; 18:489-499 10.1615/intjmedmushrooms.v18.i6.30
• Beet root juice protects against doxorubicin toxicity in cardiomyocytes while enhancing apoptosis in breast cancer cells Cite
  Das S, Filippone SM, Williams DS, Das A, Kukreja RC. Beet root juice protects against doxorubicin toxicity in cardiomyocytes while enhancing apoptosis in breast cancer cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2016; 421:89-101 10.1007/s11010-016-2789-8
• Ameliorative Influence of Dietary Dates on Doxorubicin-Induced Cardiac Toxicity Cite
  Abdalla AN, Hassan Almaliki W, Hasan Mukhtar M, Anwar F, Shahid I, Menshawi SA, et al. Ameliorative Influence of Dietary Dates on Doxorubicin-Induced Cardiac Toxicity. Pharmacology & Pharmacy. Scientific Research Publishing, Inc.; 2016; 07:343-353 10.4236/pp.2016.78042
• Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression Cite
  Dong Q, Chen L, Lu Q, Sharma S, Li L, Morimoto S, et al. Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression. British Journal of Pharmacology. Wiley; 2014; 171:4440-4454 10.1111/bph.12795
• Abstract 260: Quercetin protects from doxorubicin induced vascular toxicity but impairs its cytotoxic profile in breast cancer cells Cite
  Assiri HA, Al-Abbasi FA, El-Bassossy HM, El-Moselhy MA, Al-Abd AM. Abstract 260: Quercetin protects from doxorubicin induced vascular toxicity but impairs its cytotoxic profile in breast cancer cells. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-260
• The Effect of Caffeine and chk2 Inhibitor on Doxorubicin-Induced Cellular Senescence in MCF-7 Cells Cite
  Mohammadrezaei F, Movaghar A, Gharghabi M. The Effect of Caffeine and chk2 Inhibitor on Doxorubicin-Induced Cellular Senescence in MCF-7 Cells. Drug Research. Georg Thieme Verlag KG; 2016; 66:450-454 10.1055/s-0042-109390
• Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice Cite
  Montales MTE, Melnyk SB, Liu SJ, Simmen FA, Liu YL, Simmen RCM. Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice. Endocrine-Related Cancer. Bioscientifica; 2016; 23:677-690 10.1530/erc-16-0136
• Novel triterpenoids isolated from raisins exert potent antiproliferative activities by targeting mitochondrial and Ras/Raf/ERK signaling in human breast cancer cells Cite
  Liu J, Wang Y, Liu RH, He X. Novel triterpenoids isolated from raisins exert potent antiproliferative activities by targeting mitochondrial and Ras/Raf/ERK signaling in human breast cancer cells. Food & Function. Royal Society of Chemistry (RSC); 2016; 7:3244-3251 10.1039/c6fo00768f
• Consumption of Fresh Yellow Onion Ameliorates Hyperglycemia and Insulin Resistance in Breast Cancer Patients During Doxorubicin-Based Chemotherapy: A Randomized Controlled Clinical Trial Cite
  Jafarpour-Sadegh F, Montazeri V, Adili A, Esfehani A, Rashidi M, Pirouzpanah S. Consumption of Fresh Yellow Onion Ameliorates Hyperglycemia and Insulin Resistance in Breast Cancer Patients During Doxorubicin-Based Chemotherapy: A Randomized Controlled Clinical Trial. Integrative Cancer Therapies. SAGE Publications; 2016; 16:276-289 10.1177/1534735416656915
• Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats Cite
  Razmaraii N, Babaei H, Mohajjel Nayebi A, Assadnassab G, Ashrafi Helan J, Azarmi Y. Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats. Life Sciences. Elsevier BV; 2016; 157:145-151 10.1016/j.lfs.2016.06.012
• Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines Cite
  Pilco-Ferreto N, Calaf GM. Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines. International Journal of Oncology. Spandidos Publications; 2016; 49:753-762 10.3892/ijo.2016.3558
• Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts Cite
  Chen P, Hou C, Shibu MA, Day CH, Pai P, Liu Z, et al. Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts. Environmental Toxicology. Wiley; 2016; 32:679-689 10.1002/tox.22270
• The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters Cite
  Rigalli JP, Tocchetti GN, Arana MR, Villanueva SSM, Catania VA, Theile D, et al. The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters. Cancer Letters. Elsevier BV; 2016; 376:165-172 10.1016/j.canlet.2016.03.040
• Resveratrol improves the anticancer effects of doxorubicin in vitro and in vivo models: A mechanistic insight Cite
  Rai G, Mishra S, Suman S, Shukla Y. Resveratrol improves the anticancer effects of doxorubicin in vitro and in vivo models: A mechanistic insight. Phytomedicine. Elsevier BV; 2016; 23:233-242 10.1016/j.phymed.2015.12.020
• Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells Cite
  Sharma M, Tuaine J, McLaren B, Waters DL, Black K, Jones LM, et al. Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells. PLOS ONE. Public Library of Science (PLoS); 2016; 11:e0148049 10.1371/journal.pone.0148049
• Co-delivery with nano-quercetin enhances doxorubicin-mediated cytotoxicity against MCF-7 cells Cite
  Minaei A, Sabzichi M, Ramezani F, Hamishehkar H, Samadi N. Co-delivery with nano-quercetin enhances doxorubicin-mediated cytotoxicity against MCF-7 cells. Molecular Biology Reports. Springer Science and Business Media LLC; 2016; 43:99-105 10.1007/s11033-016-3942-x
• Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice Cite
  Adwas AA, Elkhoely AA, Kabel AM, Abdel-Rahman MN, Eissa AA. Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice. Journal of Infection and Chemotherapy. Elsevier BV; 2016; 22:36-43 10.1016/j.jiac.2015.10.001
• Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin Cite
  Effenberger-Neidnicht K, Schobert R. Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin. Cancer Chemotherapy and Pharmacology. Springer Science and Business Media LLC; 2010; 67:867-874 10.1007/s00280-010-1386-x
• Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway Cite
  Woo CC, Loo SY, Gee V, Yap CW, Sethi G, Kumar AP, et al. Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway. Biochemical Pharmacology. Elsevier BV; 2011; 82:464-475 10.1016/j.bcp.2011.05.030
• Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS Cite
  Woo CC, Hsu A, Kumar AP, Sethi G, Tan KHB. Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e75356 10.1371/journal.pone.0075356
• Abstract PR13: Circadian/melatonin disruption by dim light at night drive chemotherapy resistance in breast cancer Cite
  Hill SM, Xiang S, Dauchy RT, Mao L, Hauch A, Brimmer S, et al. Abstract PR13: Circadian/melatonin disruption by dim light at night drive chemotherapy resistance in breast cancer. Chemoprevention and Biological Therapies. American Association for Cancer Research; 2015; 10.1158/1940-6215.prev-14-pr13
• The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study Cite
  de Groot S, Vreeswijk MP, Welters MJ, Gravesteijn G, Boei JJ, Jochems A, et al. The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study. BMC Cancer. Springer Science and Business Media LLC; 2015; 15 10.1186/s12885-015-1663-5
• Benzyl butyl phthalate increases the chemoresistance to doxorubicin/cyclophosphamide by increasing breast cancer-associated dendritic cell-derived CXCL1/GROα and S100A8/A9 Cite
  HSU Y, HUNG J, TSAI E, WU C, HO Y, JIAN S, et al. Benzyl butyl phthalate increases the chemoresistance to doxorubicin/cyclophosphamide by increasing breast cancer-associated dendritic cell-derived CXCL1/GROα and S100A8/A9. Oncology Reports. Spandidos Publications; 2015; 34:2889-2900 10.3892/or.2015.4307
• Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death Cite
  BURANRAT B, CONNOR JR. Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death. Oncology Reports. Spandidos Publications; 2015; 34:2790-2796 10.3892/or.2015.4250
• Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells Cite
  Ku JM, Kim SR, Hong SH, Choi H, Seo HS, Shin YC, et al. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2015; 409:33-43 10.1007/s11010-015-2509-9
• Resveratrol, a polyphenol phytoalexin, protects against doxorubicin‐induced cardiotoxicity Cite
  Gu J, Hu W, Zhang D. Resveratrol, a polyphenol phytoalexin, protects against doxorubicin‐induced cardiotoxicity. Journal of Cellular and Molecular Medicine. Wiley; 2015; 19:2324-2328 10.1111/jcmm.12633
• Body Mass Index, PAM50 Subtype, and Outcomes in Node-Positive Breast Cancer: CALGB 9741 (Alliance) Cite
  Ligibel JA, Cirrincione CT, Liu M, Citron M, Ingle JN, Gradishar W, et al. Body Mass Index, PAM50 Subtype, and Outcomes in Node-Positive Breast Cancer: CALGB 9741 (Alliance). JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2015; 107 10.1093/jnci/djv179
• Doxorubicin and cyclophosphamide treatment produces anxiety-like behavior and spatial cognition impairment in rats: Possible involvement of hippocampal neurogenesis via brain-derived neurotrophic factor and cyclin D1 regulation Cite
  Kitamura Y, Hattori S, Yoneda S, Watanabe S, Kanemoto E, Sugimoto M, et al. Doxorubicin and cyclophosphamide treatment produces anxiety-like behavior and spatial cognition impairment in rats: Possible involvement of hippocampal neurogenesis via brain-derived neurotrophic factor and cyclin D1 regulation. Behavioural Brain Research. Elsevier BV; 2015; 292:184-193 10.1016/j.bbr.2015.06.007
• Saffron extracts alleviate cardiomyocytes injury induced by doxorubicin and ischemia-reperfusionin vitro Cite
  Chahine N, Nader M, Duca L, Martiny L, Chahine R. Saffron extracts alleviate cardiomyocytes injury induced by doxorubicin and ischemia-reperfusionin vitro. Drug and Chemical Toxicology. Informa UK Limited; 2015; 39:87-96 10.3109/01480545.2015.1036281
• The flavonoid quercetin: Possible solution for anthracycline-induced cardiotoxicity and multidrug resistance Cite
  Czepas J, Gwoździński K. The flavonoid quercetin: Possible solution for anthracycline-induced cardiotoxicity and multidrug resistance. Biomedicine & Pharmacotherapy. Elsevier BV; 2014; 68:1149-1159 10.1016/j.biopha.2014.10.013
• Chronic heart damage following doxorubicin treatment is alleviated by lovastatin Cite
  Henninger C, Huelsenbeck S, Wenzel P, Brand M, Huelsenbeck J, Schad A, et al. Chronic heart damage following doxorubicin treatment is alleviated by lovastatin. Pharmacological Research. Elsevier BV; 2015; 91:47-56 10.1016/j.phrs.2014.11.003
• Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin Cite
  Govender J, Loos B, Marais E, Engelbrecht A. Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin. Journal of Pineal Research. Wiley; 2014; 57:367-380 10.1111/jpi.12176
• Can short-term fasting protect against doxorubicin-induced cardiotoxicity? Cite
  Dirks-Naylor AJ. Can short-term fasting protect against doxorubicin-induced cardiotoxicity?. World Journal of Biological Chemistry. Baishideng Publishing Group Inc.; 2014; 5:269 10.4331/wjbc.v5.i3.269
• Risk of Hospitalization According to Chemotherapy Regimen in Early-Stage Breast Cancer Cite
  Barcenas CH, Niu J, Zhang N, Zhang Y, Buchholz TA, Elting LS, et al. Risk of Hospitalization According to Chemotherapy Regimen in Early-Stage Breast Cancer. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2014; 32:2010-2017 10.1200/jco.2013.49.3676
• Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation Cite
  Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Prasad SVN, et al. Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation. Journal of Clinical Investigation. American Society for Clinical Investigation; 2014; 124:617-630 10.1172/jci72931
• Doxorubicin-Induced Oxidative Stress in Rats Is Efficiently Counteracted by Dietary Anthocyanin Differently Enriched Strawberry (Fragaria × ananassa Duch.) Cite
  Diamanti J, Mezzetti B, Giampieri F, Alvarez-Suarez JM, Quiles JL, Gonzalez-Alonso A, et al. Doxorubicin-Induced Oxidative Stress in Rats Is Efficiently Counteracted by Dietary Anthocyanin Differently Enriched Strawberry (Fragaria × ananassa Duch.). Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2014; 62:3935-3943 10.1021/jf405721d
• Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin Cite
  Kim TH, Shin YJ, Won AJ, Lee BM, Choi WS, Jung JH, et al. Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin. Biochimica et Biophysica Acta (BBA) - General Subjects. Elsevier BV; 2014; 1840:615-625 10.1016/j.bbagen.2013.10.023
• Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells Cite
  Qu C, Zhang W, Zheng G, Zhang Z, Yin J, He Z. Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2013; 386:63-71 10.1007/s11010-013-1845-x
• DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA Cite
  Rahman MM, Veigas JM, Williams PJ, Fernandes G. DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 141:341-352 10.1007/s10549-013-2703-y
• Dietary Trans Fats Enhance Doxorubicin-Induced Cardiotoxicity in Mice Cite
  Mong M, Hsia T, Yin M. Dietary Trans Fats Enhance Doxorubicin-Induced Cardiotoxicity in Mice. Journal of Food Science. Wiley; 2013; 78:H1621-H1628 10.1111/1750-3841.12257
• Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin Cite
  CHEKHUN VF, LUKYANOVA NY, BURLAKA AP, BEZDENEZHNYKH NA, SHPYLEVA SI, TRYNDYAK VP, et al. Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin. International Journal of Oncology. Spandidos Publications; 2013; 43:1481-1486 10.3892/ijo.2013.2063
• Protective effect of melatonin against Adriamycin-induced cardiotoxicity Cite
  ZHANG Y, LI L, XIANG C, MA Z, MA T, ZHU S. Protective effect of melatonin against Adriamycin-induced cardiotoxicity. Experimental and Therapeutic Medicine. Spandidos Publications; 2013; 5:1496-1500 10.3892/etm.2013.989
• Proteomic Profiling Reveals That Resveratrol Inhibits HSP27 Expression and Sensitizes Breast Cancer Cells to Doxorubicin Therapy Cite
  Díaz-Chávez J, Fonseca-Sánchez MA, Arechaga-Ocampo E, Flores-Pérez A, Palacios-Rodríguez Y, Domínguez-Gómez G, et al. Proteomic Profiling Reveals That Resveratrol Inhibits HSP27 Expression and Sensitizes Breast Cancer Cells to Doxorubicin Therapy. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e64378 10.1371/journal.pone.0064378
• Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice Cite
  Dolinsky VW, Rogan KJ, Sung MM, Zordoky BN, Haykowsky MJ, Young ME, et al. Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice. American Journal of Physiology-Endocrinology and Metabolism. American Physiological Society; 2013; 305:E243-E253 10.1152/ajpendo.00044.2013
• Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts Cite
  Nayak PG, Paul P, Bansal P, Kutty NG, Pai KSR. Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts. Journal of Pharmacy and Pharmacology. Wiley; 2013; 65:1083-1093 10.1111/jphp.12073
• 3,3′-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway Cite
  Yao Z, Hu W, Yin S, Huang Z, Zhu Q, Chen J, et al. 3,3′-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway. Pharmacological Research. Elsevier BV; 2013; 70:139-146 10.1016/j.phrs.2013.01.006
• Preventive Effects of Ellagic Acid Against Doxorubicin-Induced Cardio-Toxicity in Mice Cite
  Lin M, Yin M. Preventive Effects of Ellagic Acid Against Doxorubicin-Induced Cardio-Toxicity in Mice. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2013; 13:185-193 10.1007/s12012-013-9197-z
• Docosahexanoic Acid Improves Chemotherapy Efficacy by Inducing CD95 Translocation to Lipid Rafts in ER− Breast Cancer Cells Cite
  Ewaschuk JB, Newell M, Field CJ. Docosahexanoic Acid Improves Chemotherapy Efficacy by Inducing CD95 Translocation to Lipid Rafts in ER− Breast Cancer Cells. Lipids. Wiley; 2012; 47:1019-1030 10.1007/s11745-012-3717-7
• Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study Cite
  Bowles EJA, Wellman R, Feigelson HS, Onitilo AA, Freedman AN, Delate T, et al. Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2012; 104:1293-1305 10.1093/jnci/djs317
• The Effect of Quercetin on Doxorubicin Cytotoxicity in Human Breast Cancer Cells Cite
  Li S, Li K, Zhang J, Dong Z. The Effect of Quercetin on Doxorubicin Cytotoxicity in Human Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry. Bentham Science Publishers Ltd.; 2013; 13:352-355 10.2174/1871520611313020020
• Diindolilmethane (DIM) selectively inhibits cancer stem cells Cite
  Semov A, Iourtchenco L, Lin Fang L, Shengmin L, Xu Y, Su X, et al. Diindolilmethane (DIM) selectively inhibits cancer stem cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2012; 424:45-51 10.1016/j.bbrc.2012.06.062
• Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin Cite
  Choi S, Shin S, Choi J. Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin. Archives of Pharmacal Research. Springer Science and Business Media LLC; 2011; 34:309-315 10.1007/s12272-011-0217-x
• Longer Therapy, Iatrogenic Amenorrhea, and Survival in Early Breast Cancer Cite
  Swain SM, Jeong J, Geyer CE, Costantino JP, Pajon ER, Fehrenbacher L, et al. Longer Therapy, Iatrogenic Amenorrhea, and Survival in Early Breast Cancer. New England Journal of Medicine. Massachusetts Medical Society; 2010; 362:2053-2065 10.1056/nejmoa0909638
• Antioxidant and anti-apoptotic effects of onion (Allium cepa) extract on doxorubicin-induced cardiotoxicity in rats Cite
  Alpsoy S, Aktas C, Uygur R, Topcu B, Kanter M, Erboga M, et al. Antioxidant and anti-apoptotic effects of onion (Allium cepa) extract on doxorubicin-induced cardiotoxicity in rats. Journal of Applied Toxicology. Wiley; 2011; 33:202-208 10.1002/jat.1738
• Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity Cite
  El-Demerdash E, Ali AA, El-Taher DE, Hamada FM. Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity. Journal of Pharmacy and Pharmacology. Wiley; 2011; 64:344-352 10.1111/j.2042-7158.2011.01413.x
• Cardioprotective activity of melatonin and its novel synthesized derivatives on doxorubicin-induced cardiotoxicity Cite
  Ahmed HH, Mannaa F, Elmegeed GA, Doss SH. Cardioprotective activity of melatonin and its novel synthesized derivatives on doxorubicin-induced cardiotoxicity. Bioorganic & Medicinal Chemistry. Elsevier BV; 2005; 13:1847-1857 10.1016/j.bmc.2004.10.066
• Grape Seed and Skin Extract Protects Against Acute Chemotherapy Toxicity induced by Doxorubicin in Rat Heart Cite
  Mokni M, Hamlaoui-Guesmi S, Amri M, Marzouki L, Limam F, Aouani E. Grape Seed and Skin Extract Protects Against Acute Chemotherapy Toxicity induced by Doxorubicin in Rat Heart. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2012; 12:158-165 10.1007/s12012-012-9155-1
• Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats Cite
  Swamy A, Gulliaya S, Thippeswamy A, Koti B, Manjula D. Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats. Indian Journal of Pharmacology. Medknow; 2012; 44:73 10.4103/0253-7613.91871
• Reversion of multidrug resistance by co-encapsulation of doxorubicin and curcumin in chitosan/poly(butyl cyanoacrylate) nanoparticles Cite
  Duan J, Mansour HM, Zhang Y, Deng X, Chen Y, Wang J, et al. Reversion of multidrug resistance by co-encapsulation of doxorubicin and curcumin in chitosan/poly(butyl cyanoacrylate) nanoparticles. International Journal of Pharmaceutics. Elsevier BV; 2012; 426:193-201 10.1016/j.ijpharm.2012.01.020
• Modulation by Melatonin of the Cardiotoxic and Antitumor Activities of Adriamycin Cite
  Kim C, Kim N, Joo H, Youm JB, Park WS, Cuong DV, et al. Modulation by Melatonin of the Cardiotoxic and Antitumor Activities of Adriamycin. Journal of Cardiovascular Pharmacology. Ovid Technologies (Wolters Kluwer Health); 2005; 46:200-210 10.1097/01.fjc.0000171750.97822.a2
• New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals Cite
  Souček P, Kondrová E, Heřmánek J, Stopka P, Boumendjel A, Ueng Y, et al. New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anti-Cancer Drugs. Ovid Technologies (Wolters Kluwer Health); 2011; 22:176-184 10.1097/cad.0b013e328341a17b
• Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro Cite
  Xiao J, Sun G, Sun B, Wu Y, He L, Wang X, et al. Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. Toxicology. Elsevier BV; 2012; 292:53-62 10.1016/j.tox.2011.11.018
• Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats Cite
  Elberry AA, Abdel-Naim AB, Abdel-Sattar EA, Nagy AA, Mosli HA, Mohamadin AM, et al. Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats. Food and Chemical Toxicology. Elsevier BV; 2010; 48:1178-1184 10.1016/j.fct.2010.02.008
• Trastuzumab Adjuvant Chemotherapy and Cardiotoxicity in Real-World Women With Breast Cancer Cite
  Tarantini L, Cioffi G, Gori S, Tuccia F, Boccardi L, Bovelli D, et al. Trastuzumab Adjuvant Chemotherapy and Cardiotoxicity in Real-World Women With Breast Cancer. Journal of Cardiac Failure. Elsevier BV; 2012; 18:113-119 10.1016/j.cardfail.2011.10.015
• Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials Cite
  Early Breast Cancer Trialists' Collaborative Group (EBCTCG) . Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials. The Lancet. Elsevier BV; 2012; 379:432-444 10.1016/s0140-6736(11)61625-5
• C-B2-01: Cardiotoxic Chemotherapy is Associated with Increased Heart Failure Risk Among Women with Breast Cancer in the Cancer Research Network Cite
  Bowles EA, Wellman R, Delate T, Allen L, Feigelson HS, Yood MU, et al. C-B2-01: Cardiotoxic Chemotherapy is Associated with Increased Heart Failure Risk Among Women with Breast Cancer in the Cancer Research Network. Clinical Medicine & Research. Marshfield Clinic Research Foundation; 2011; 9:148-148 10.3121/cmr.2011.1020.c-b2-01
• Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro Cite
  Al-Abd AM, Mahmoud AM, El-Sherbiny GA, El-Moselhy MA, Nofal SM, El-Latif HA, et al. Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro. Cell Proliferation. Wiley; 2011; 44:591-601 10.1111/j.1365-2184.2011.00783.x
• Curcumin Enhances the Efficacy of Chemotherapy by Tailoring p65NFκB-p300 Cross-talk in Favor of p53-p300 in Breast Cancer Cite
  Sen GS, Mohanty S, Hossain DMS, Bhattacharyya S, Banerjee S, Chakraborty J, et al. Curcumin Enhances the Efficacy of Chemotherapy by Tailoring p65NFκB-p300 Cross-talk in Favor of p53-p300 in Breast Cancer. Journal of Biological Chemistry. American Society for Biochemistry & Molecular Biology (ASBMB); 2011; 286:42232-42247 10.1074/jbc.m111.262295
• Adjuvant Trastuzumab in HER2-Positive Breast Cancer Cite
  Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M, et al. Adjuvant Trastuzumab in HER2-Positive Breast Cancer. New England Journal of Medicine. Massachusetts Medical Society; 2011; 365:1273-1283 10.1056/nejmoa0910383
• Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine Cite
  Hill GM. Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine. Scientia Pharmaceutica. MDPI AG; 2011; 79:729-747 10.3797/scipharm.1107-19
• Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells Cite
  Li S, Lei Y, Jia Y, Li N, Wink M, Ma Y. Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells. Phytomedicine. Elsevier BV; 2011; 19:83-87 10.1016/j.phymed.2011.06.031
• Interaction of celecoxib with different anti-cancer drugs is antagonistic in breast but not in other cancer cells Cite
  El-Awady RA, Saleh EM, Ezz M, Elsayed AM. Interaction of celecoxib with different anti-cancer drugs is antagonistic in breast but not in other cancer cells. Toxicology and Applied Pharmacology. Elsevier BV; 2011; 255:271-286 10.1016/j.taap.2011.06.019
• Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin Cite
  Choi J, Piao Y, Kang KW. Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin. Archives of Pharmacal Research. Springer Science and Business Media LLC; 2011; 34:607-613 10.1007/s12272-011-0411-x
• Pathology of late-onset anthracycline cardiomyopathy Cite
  Bernaba BN, Chan JB, Lai CK, Fishbein MC. Pathology of late-onset anthracycline cardiomyopathy. Cardiovascular Pathology. Elsevier BV; 2010; 19:308-311 10.1016/j.carpath.2009.07.004
• Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology Cite
  Eschenhagen T, Force T, Ewer MS, de Keulenaer GW, Suter TM, Anker SD, et al. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure. Wiley; 2011; 13:1-10 10.1093/eurjhf/hfq213
• Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics Cite
  Calcagno AM, Salcido CD, Gillet J, Wu C, Fostel JM, Mumau MD, et al. Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics. JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2010; 102:1637-1652 10.1093/jnci/djq361
• Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage Cite
  Tatlidede E, Şehirli Ö, Velioğlu-Öğünç A, Çetinel Ş, Yeğen BÇ, Yarat A, et al. Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage. Free Radical Research. Informa UK Limited; 2009; 43:195-205 10.1080/10715760802673008
• Early identification of trastuzumab-related cardiotoxicity with speckle-tracking echocardiography. Cite
  Maurea N, De Lorenzo C, Coppola C, Ragone G, Di Pietro E, Schiattarella G, et al. Early identification of trastuzumab-related cardiotoxicity with speckle-tracking echocardiography.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2010; 28:e11096-e11096 10.1200/jco.2010.28.15_suppl.e11096
• Hematologic toxicity with adjuvant docetaxel and cyclophosphamide in early breast cancer. Cite
  Santos FN, Cruz MR, Cezana L, Costa LA, de Azevedo CA, De Barros E Silva MJ, et al. Hematologic toxicity with adjuvant docetaxel and cyclophosphamide in early breast cancer.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2010; 28:e11081-e11081 10.1200/jco.2010.28.15_suppl.e11081
• Late pancreatic toxicity in patients with breast cancer after taxane-anthracycline–based neoadjuvant and adjuvant chemotherapy. Cite
  Kopp MV, Koroleva I, Kasulin AN, Kucheryavyy JA, Byakhov MJ. Late pancreatic toxicity in patients with breast cancer after taxane-anthracycline–based neoadjuvant and adjuvant chemotherapy.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2010; 28:e11043-e11043 10.1200/jco.2010.28.15_suppl.e11043
• Hepatotoxicity in breast cancer patients post-chemotherapy with docetaxel, doxorubucin, and cyclophosphamide. Cite
  Wills SM, Reid R, Jaiyesimi IA, Margolis JH. Hepatotoxicity in breast cancer patients post-chemotherapy with docetaxel, doxorubucin, and cyclophosphamide.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2010; 28:e11031-e11031 10.1200/jco.2010.28.15_suppl.e11031
• Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells Cite
  Du G, Song Z, Lin H, Han X, Zhang S, Yang Y. Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2008; 372:497-502 10.1016/j.bbrc.2008.05.080
• Effects of Exercise Training on Antitumor Efficacy of Doxorubicin in MDA-MB-231 Breast Cancer Xenografts Cite
  Jones LW, Eves ND, Courneya KS, Chiu BK, Baracos VE, Hanson J, et al. Effects of Exercise Training on Antitumor Efficacy of Doxorubicin in MDA-MB-231 Breast Cancer Xenografts. Clinical Cancer Research. American Association for Cancer Research (AACR); 2005; 11:6695-6698 10.1158/1078-0432.ccr-05-0844
• Abstract 3223: Severe dietary restriction enhances cancer treatment: Protecting normal cells and sensitizing malignant cells to chemotherapy by fasting Cite
  Lee C, Safdie F, Raffaghello L, Wei M, Longo V. Abstract 3223: Severe dietary restriction enhances cancer treatment: Protecting normal cells and sensitizing malignant cells to chemotherapy by fasting. Cellular and Molecular Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-3223
• Decrease in Breast Density in the Contralateral Normal Breast of Patients Receiving Neoadjuvant Chemotherapy: MR Imaging Evaluation Cite
  Chen J, Nie K, Bahri S, Hsu C, Hsu F, Shih H, et al. Decrease in Breast Density in the Contralateral Normal Breast of Patients Receiving Neoadjuvant Chemotherapy: MR Imaging Evaluation. Radiology. Radiological Society of North America (RSNA); 2010; 255:44-52 10.1148/radiol.09091090
• Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats Cite
  Alkreathy H, Damanhouri ZA, Ahmed N, Slevin M, Ali SS, Osman AM. Aged garlic extract protects against doxorubicin-induced cardiotoxicity in rats. Food and Chemical Toxicology. Elsevier BV; 2010; 48:951-956 10.1016/j.fct.2010.01.005
• Patterns of Local and Distant Disease Relapse in Patients with Breast Cancer Treated with Primary Chemotherapy: Do Patients with a Complete Pathological Response Differ from Those with Residual Tumour in the Breast? Cite
  Chaturvedi S, McLaren C, Schofield AC, Ogston KN, Sarkar TK, Hutcheon AW, et al. Patterns of Local and Distant Disease Relapse in Patients with Breast Cancer Treated with Primary Chemotherapy: Do Patients with a Complete Pathological Response Differ from Those with Residual Tumour in the Breast?. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2005; 93:151-158 10.1007/s10549-005-4615-y
• Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission Cite
  Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission. Cancer Research. American Association for Cancer Research (AACR); 2009; 69:7507-7511 10.1158/0008-5472.can-09-2994
• Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids Cite
  Čipák L, Novotný L, Čipáková I, Rauko P. Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids. Nutrition Research. Elsevier BV; 2003; 23:1045-1057 10.1016/s0271-5317(03)00078-2