Tag: cucumber

News

02/25/18

Cucumber has anti-cancer activities in ER+, HER2+ and TN cells

Foods

• • cucumbers

Studies

• Synthetic Modifications of Therapeutically Relevant Pre-assembled Cucurbitacins: Synthetic Strategies and Structure-Activity Relationships Cite
  Sharma R, Thakur S, Natish , Kumar M, Vamsi K, Jachak S, et al. Synthetic Modifications of Therapeutically Relevant Pre-assembled Cucurbitacins: Synthetic Strategies and Structure-Activity Relationships. Journal of Molecular Structure. Elsevier BV; 2024;:138321 10.1016/j.molstruc.2024.138321
• Potential of cucurbitacin as an anticancer drug Cite
  Li Y, Li Y, Yao Y, Li H, Gao C, Sun C, et al. Potential of cucurbitacin as an anticancer drug. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 168:115707 10.1016/j.biopha.2023.115707
• Recent Advances in the Application of Cucurbitacins as Anticancer Agents Cite
  Zieniuk B, Pawełkowicz M. Recent Advances in the Application of Cucurbitacins as Anticancer Agents. Metabolites. MDPI AG; 2023; 13:1081 10.3390/metabo13101081
• Cucurbitacin B: A Review of its Pharmacology, Toxicity, and Pharmacokinetics Cite
  Dai S, Wang C, Zhao X, Ma C, Fu K, Liu Y, et al. Cucurbitacin B: A Review of its Pharmacology, Toxicity, and Pharmacokinetics. Pharmacological Research. Elsevier BV; 2022;:106587 10.1016/j.phrs.2022.106587
• Nanoparticle-based toxicity in perishable vegetable crops: Molecular insights, impact on human health and mitigation strategies for sustainable cultivation Cite
  Sharma S, Shree B, Aditika , Sharma A, Irfan M, Kumar P. Nanoparticle-based toxicity in perishable vegetable crops: Molecular insights, impact on human health and mitigation strategies for sustainable cultivation. Environmental Research. Elsevier BV; 2022; 212:113168 10.1016/j.envres.2022.113168
• Fate of Bioactive Compounds during Lactic Acid Fermentation of Fruits and Vegetables Cite
  Paramithiotis S, Das G, Shin H, Patra JK. Fate of Bioactive Compounds during Lactic Acid Fermentation of Fruits and Vegetables. Foods. MDPI AG; 2022; 11:733 10.3390/foods11050733
• Identification of seven undescribed cucurbitacins in Cucumis sativus (cucumber) and their cytotoxic activity Cite
  Qing Z, Shi Y, Han L, Li P, Zha Z, Liu C, et al. Identification of seven undescribed cucurbitacins in Cucumis sativus (cucumber) and their cytotoxic activity. Phytochemistry. Elsevier BV; 2022; 197:113123 10.1016/j.phytochem.2022.113123
• Antioxidant and cytotoxic activity of isoindole compounds in breast cancer cells (MCF-7) Cite
  Mesci S, Gül M, Eryılmaz S, Lis T, Szafert S, Yıldırım T. Antioxidant and cytotoxic activity of isoindole compounds in breast cancer cells (MCF-7). Journal of Molecular Structure. Elsevier BV; 2020; 1217:128366 10.1016/j.molstruc.2020.128366
• Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage Cite
  Bakar-Ates F, Ozkan E, Sengel-Turk CT. Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage. International Journal of Pharmaceutics. Elsevier BV; 2020; 586:119565 10.1016/j.ijpharm.2020.119565
• Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells Cite
  Saeed ME, Boulos JC, Elhaboub G, Rigano D, Saab A, Loizzo MR, et al. Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells. Phytomedicine. Elsevier BV; 2019; 62:152945 10.1016/j.phymed.2019.152945
• Cucurbitacin B Induces Hypermethylation of Oncogenes in Breast Cancer Cells Cite
  Dittharot K, Dakeng S, Suebsakwong P, Suksamrarn A, Patmasiriwat P, Promkan M. Cucurbitacin B Induces Hypermethylation of Oncogenes in Breast Cancer Cells. Planta Medica. Georg Thieme Verlag KG; 2018; 85:370-378 10.1055/a-0791-1591
• Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells Cite
  Ku JM, Kim SR, Hong SH, Choi H, Seo HS, Shin YC, et al. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. Molecular and Cellular Biochemistry. Springer Science and Business Media LLC; 2015; 409:33-43 10.1007/s11010-015-2509-9
• Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Cite
  Ren G, Sha T, Guo J, Li W, Lu J, Chen X. Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells. Journal of Natural Medicines. Springer Science and Business Media LLC; 2015; 69:522-530 10.1007/s11418-015-0918-4
• Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery Cite
  Hall JA, Seedarala S, Rice N, Kopel L, Halaweish F, Blagg BSJ. Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery. Journal of Natural Products. American Chemical Society (ACS); 2015; 78:873-879 10.1021/acs.jnatprod.5b00054
• Review on anti-tumor effect of triterpene acid compounds Cite
  Lei P, Zhang W, Men X. Review on anti-tumor effect of triterpene acid compounds. Journal of Cancer Research and Therapeutics. Medknow; 2014; 10:14 10.4103/0973-1482.139746
• Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer Cite
  Kong Y, Chen J, Zhou Z, Xia H, Qiu M, Chen C. Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e103760 10.1371/journal.pone.0103760
• Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB Cite
  Goh FY, Upton N, Guan S, Cheng C, Shanmugam MK, Sethi G, et al. Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB. European Journal of Pharmacology. Elsevier BV; 2012; 679:109-116 10.1016/j.ejphar.2012.01.002
• Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy Cite
  Chiu S. Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy. International Journal of Oncology. Spandidos Publications; 2011; 10.3892/ijo.2011.1203
• Lipid-lowering action of pectin from Cucumis sativus Cite
  Sudheesh S, Vijayalakshmi N. Lipid-lowering action of pectin from Cucumis sativus. Food Chemistry. Elsevier BV; 1999; 67:281-286 10.1016/s0308-8146(99)00135-1
• Brassinosteroids Promote Metabolism of Pesticides in Cucumber Cite
  Xia XJ, Zhang Y, Wu JX, Wang JT, Zhou YH, Shi K, et al. Brassinosteroids Promote Metabolism of Pesticides in Cucumber. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2009; 57:8406-8413 10.1021/jf901915a
• A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF- B-signaling pathways Cite
  Suh Y, Afaq F, Johnson JJ, Mukhtar H. A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF- B-signaling pathways. Carcinogenesis. Oxford University Press (OUP); 2008; 30:300-307 10.1093/carcin/bgn269
• Comparisons of food intake between breast cancer patients and controls in Korean women Cite
  Kim E, Hong Y, Jeon H, Sung M, Sung C. Comparisons of food intake between breast cancer patients and controls in Korean women. Nutrition Research and Practice. The Korean Nutrition Society and The Korean Society of Community Nutrition; 2007; 1:237 10.4162/nrp.2007.1.3.237
• Antioxidant and Antiproliferative Activities of Common Vegetables Cite
  Chu Y, Sun J, Wu X, Liu RH. Antioxidant and Antiproliferative Activities of Common Vegetables. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2002; 50:6910-6916 10.1021/jf020665f