Tag: cardiomyopathy
Cardiomyopathy: Heart muscle damage that can result in cardiac dysfunction and congestive heart failure. Chemotherapy drugs known to induce cardiomyopathy include anthracyclines such as Adriamycin and epirubicin, as well as 5-fluorouracil, and cisplatin.
Articles
- BRCA1 and BRCA2 mutation carriers
- Factors influencing Adriamycin (doxorubicin) effectiveness
- Influence of BMI, metabolic syndrome and diabetes on TN prognosis
News
- 09/26/17
- Black cumin enhances Adriamycin toxicity and reduces cardiomyopathy
- 08/09/16
- Quercetin could interfere with Adriamycin treatment
- 05/30/12
- Fish oil might promote Adriamycin-induced heart damage
- 03/08/12
- Heart drug digoxin (digitalis) increases risk of breast cancer
- 02/15/12
- Grapes might help protect against Adriamycin-induced heart damage
- 12/01/11
- Herceptin + anthracycline chemo increases risk of cardiomyopathy
Studies
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Abstract 4147821: Physical Activity Impacts Cardiac Tissue Mitochondrial Respiration During Anthracycline Chemotherapy
Cite
Riojas A, Harbert S, Lacy J, Piloso J, Kramer P, Weis J, et al. Abstract 4147821: Physical Activity Impacts Cardiac Tissue Mitochondrial Respiration During Anthracycline Chemotherapy. Circulation. Ovid Technologies (Wolters Kluwer Health); 2024; 150 10.1161/circ.150.suppl_1.4147821
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Chamomile Extract Reduces Cardiac Toxicity in Female Mice with Ehrlich Solid Carcinoma
Cite
Abosharaf HA, Farag AM, Abdel Allem AAH, El-Sayed IET, Akela MA, Tousson E, et al. Chamomile Extract Reduces Cardiac Toxicity in Female Mice with Ehrlich Solid Carcinoma. Cell Biochemistry and Biophysics. Springer Science and Business Media LLC; 2024; 10.1007/s12013-024-01476-6
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Possible protective effect of rosuvastatin in chemotherapy-induced cardiotoxicity in HER2 positive breast cancer patients: a randomized controlled trial
Cite
Kettana KM, El‑Haggar SM, Alm El-Din MA, El‑Afify DR. Possible protective effect of rosuvastatin in chemotherapy-induced cardiotoxicity in HER2 positive breast cancer patients: a randomized controlled trial. Medical Oncology. Springer Science and Business Media LLC; 2024; 41 10.1007/s12032-024-02426-1
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Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis
Cite
Bucci T, Gue Y, Dobson R, Palmieri C, Pignatelli P, Lip GYH. Statin use is associated with a lower risk of all-cause death in patients with breast cancer treated with anthracycline containing regimens: a global federated health database analysis. Clinical and Experimental Medicine. Springer Science and Business Media LLC; 2024; 24 10.1007/s10238-024-01395-z
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Beta-blocker use and breast cancer outcomes: a meta-analysis
Cite
Scott OW, TinTin S, Cavadino A, Elwood JM. Beta-blocker use and breast cancer outcomes: a meta-analysis. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2024; 10.1007/s10549-024-07263-4
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Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study
Cite
Strell C, Smith DR, Valachis A, Woldeyesus H, Wadsten C, Micke P, et al. Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2024; 10.1007/s10549-024-07358-y
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Heart Failure Post-Myocardial Infarction Promotes Mammary Tumor Growth Through the NGF-TRKA Pathway
Cite
Tani T, Oikawa M, Misaka T, Ishida T, Takeishi Y. Heart Failure Post-Myocardial Infarction Promotes Mammary Tumor Growth Through the NGF-TRKA Pathway. JACC: CardioOncology. Elsevier BV; 2024; 6:55-66 10.1016/j.jaccao.2023.10.002
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Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
Cite
Li C, Stražar M, Mohamed AM, Pacheco JA, Walker RL, Lebar T, et al. Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria. Cell. Elsevier BV; 2024; 10.1016/j.cell.2024.03.014
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The efficacy and safety of exercise regimens to mitigate chemotherapy cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials
Cite
Amin AM, Khlidj Y, Abuelazm M, Ibrahim AA, Tanashat M, Imran M, et al. The efficacy and safety of exercise regimens to mitigate chemotherapy cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials. Cardio-Oncology. Springer Science and Business Media LLC; 2024; 10 10.1186/s40959-024-00208-2
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Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab
Cite
Zhou S, Cirne F, Chow J, Zereshkian A, Bordeleau L, Dhesy-Thind S, et al. Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab. The Oncologist. Oxford University Press (OUP); 2023; 28:e712-e722 10.1093/oncolo/oyad086
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The Impact of Chemotherapy on Cardiovascular Mortality across Breast Cancer Subtypes
Cite
Ngô TM, Lê ÁN, Đinh DPH. The Impact of Chemotherapy on Cardiovascular Mortality across Breast Cancer Subtypes. Current Oncology. MDPI AG; 2024; 31:649-659 10.3390/curroncol31020047
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Impact of Beta Blockers on Breast Cancer Incidence and Prognosis
Cite
Yang J, Zhang S, Jiang W. Impact of Beta Blockers on Breast Cancer Incidence and Prognosis. Clinical Breast Cancer. Elsevier BV; 2023; 23:664-671.e21 10.1016/j.clbc.2023.05.014
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Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions
Cite
Liu C, Chen H, Guo S, Liu Q, Chen Z, Huang H, et al. Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions. Biomedicine & Pharmacotherapy. Elsevier BV; 2023; 166:115373 10.1016/j.biopha.2023.115373
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Racial Disparity in Anthracycline-induced Cardiotoxicity in Breast Cancer Patients
Cite
Balaji S, Antony AK, Tonchev H, Scichilone G, Morsy M, Deen H, et al. Racial Disparity in Anthracycline-induced Cardiotoxicity in Breast Cancer Patients. Biomedicines. MDPI AG; 2023; 11:2286 10.3390/biomedicines11082286
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Use of calcium channel blockers does not increase breast cancer risk: findings from a nationwide population-based cohort study in Taiwan
Cite
Minegishi S. Use of calcium channel blockers does not increase breast cancer risk: findings from a nationwide population-based cohort study in Taiwan. Hypertension Research. Springer Science and Business Media LLC; 2023; 10.1038/s41440-023-01382-z
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Association between insulin resistance and cardiac remodeling in HER2-positive breast cancer patients: a real-world study
Cite
Shi Y, Qiu Z, Yu J, Li Z, Hua S, Chen Y, et al. Association between insulin resistance and cardiac remodeling in HER2-positive breast cancer patients: a real-world study. BMC Cancer. Springer Science and Business Media LLC; 2023; 23 10.1186/s12885-023-11102-y
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Survival outcomes of beta-blocker usage in HER2-positive advanced breast cancer patients: a retrospective cohort study
Cite
Hsieh H, Wu T, Chen C, Kuo Y, Hour M. Survival outcomes of beta-blocker usage in HER2-positive advanced breast cancer patients: a retrospective cohort study. Therapeutic Advances in Drug Safety. SAGE Publications; 2023; 14 10.1177/20420986231181338
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Use of calcium channel blockers and risk of breast cancer among women aged 55 years and older: a nationwide population-based cohort study
Cite
Lin S, Huang H, Chiang L, Huang L, Wang C. Use of calcium channel blockers and risk of breast cancer among women aged 55 years and older: a nationwide population-based cohort study. Hypertension Research. Springer Science and Business Media LLC; 2023; 10.1038/s41440-023-01321-y
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Mechanism of Saffron Extract against Cardiotoxicity Induced by Doxorubicin: 4D Label-Free Quantitative proteomics Analysis and Bioinformatic Study
Cite
Sa R, Lin Z, Huang J, Wang Y, Lv J, Zhang X, et al. Mechanism of Saffron Extract against Cardiotoxicity Induced by Doxorubicin: 4D Label-Free Quantitative proteomics Analysis and Bioinformatic Study. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2580481/v1
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Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010
Cite
Larsen CM, Garcia Arango M, Dasari H, Arciniegas Calle M, Adjei E, Rico Mesa J, et al. Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010. JAMA Network Open. American Medical Association (AMA); 2023; 6:e2254669 10.1001/jamanetworkopen.2022.54669
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An Olive Oil Mill Wastewater Extract Improves Chemotherapeutic Activity Against Breast Cancer Cells While Protecting From Cardiotoxicity
Cite
Benedetto N, Calabrone L, Gutmańska K, Macrì N, Cerrito MG, Ricotta R, et al. An Olive Oil Mill Wastewater Extract Improves Chemotherapeutic Activity Against Breast Cancer Cells While Protecting From Cardiotoxicity. Frontiers in Cardiovascular Medicine. Frontiers Media SA; 2022; 9 10.3389/fcvm.2022.867867
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Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy
Cite
Arinno A, Maneechote C, Khuanjing T, Prathumsap N, Chunchai T, Arunsak B, et al. Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Elsevier BV; 2023; 1869:166618 10.1016/j.bbadis.2022.166618
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Exercise for the Prevention of Anthracycline-induced Functional Disability and Cardiac Dysfunction: The BReast Cancer Randomized EXercise InTervention (BREXIT) Study
Cite
Foulkes SJ, Howden EJ, Haykowsky MJ, Antill Y, Salim A, Nightingale SS, et al. Exercise for the Prevention of Anthracycline-induced Functional Disability and Cardiac Dysfunction: The BReast Cancer Randomized EXercise InTervention (BREXIT) Study. Circulation. Ovid Technologies (Wolters Kluwer Health); 2022; 10.1161/circulationaha.122.062814
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Potential Cardioprotective Effects and Lipid Mediator Differences in Long-Chain Omega-3 Polyunsaturated Fatty Acid Supplemented Mice Given Chemotherapy
Cite
Angelotti A, Snoke DB, Ormiston K, Cole RM, Borkowski K, Newman JW, et al. Potential Cardioprotective Effects and Lipid Mediator Differences in Long-Chain Omega-3 Polyunsaturated Fatty Acid Supplemented Mice Given Chemotherapy. Metabolites. MDPI AG; 2022; 12:782 10.3390/metabo12090782
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Cardioprotective effects of Ferulic acid against various drugs and toxic agents
Cite
Pandi A, Raghu MH, Chandrashekar N, Kalappan VM. Cardioprotective effects of Ferulic acid against various drugs and toxic agents. Beni-Suef University Journal of Basic and Applied Sciences. Springer Science and Business Media LLC; 2022; 11 10.1186/s43088-022-00273-5
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β-blockers and breast cancer survival by molecular subtypes: a population-based cohort study and meta-analysis
Cite
Løfling LL, Støer NC, Sloan EK, Chang A, Gandini S, Ursin G, et al. β-blockers and breast cancer survival by molecular subtypes: a population-based cohort study and meta-analysis. British Journal of Cancer. Springer Science and Business Media LLC; 2022; 10.1038/s41416-022-01891-7
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Effects of exercise during adjuvant chemotherapy for breast cancer on long-term cardiotoxicity.
Cite
Naaktgeboren W, Stuiver MM, van Harten WH, Aaronson NK, Scott J, Sonke GS, et al. Effects of exercise during adjuvant chemotherapy for breast cancer on long-term cardiotoxicity.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2022; 40:12081-12081 10.1200/jco.2022.40.16_suppl.12081
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Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients
Cite
Werida RH, Elshafiey RA, Ghoneim A, Elzawawy S, Mostafa TM. Role of alpha-lipoic acid in counteracting paclitaxel- and doxorubicin-induced toxicities: a randomized controlled trial in breast cancer patients. Supportive Care in Cancer. Springer Science and Business Media LLC; 2022; 10.1007/s00520-022-07124-0
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Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors
Cite
Nijhof AVO-, Jacobse JN, Steggink LC, Lefrandt JD, Gietema JA, Leeuwen FEV, et al. Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors. Research Square Platform LLC; 2022; 10.21203/rs.3.rs-1626546/v1
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Protective Effect of Curcumin, Chrysin and Thymoquinone Injection on Trastuzumab-Induced Cardiotoxicity via Mitochondrial Protection
Cite
Shirmard LR, Shabani M, Moghadam AA, Zamani N, Ghanbari H, Salimi A. Protective Effect of Curcumin, Chrysin and Thymoquinone Injection on Trastuzumab-Induced Cardiotoxicity via Mitochondrial Protection. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2022; 10.1007/s12012-022-09750-w
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Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats
Cite
Patil C, Wagh S, Patil K, Mahajan U, Bagal P, Wadkar A, et al. Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats. Asian Pacific Journal of Tropical Biomedicine. Medknow; 2022; 12:124 10.4103/2221-1691.338921
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Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice
Cite
Eekhoudt CR, Bortoluzzi T, Varghese SS, Cheung DYC, Christie S, Eastman S, et al. Comparing Flaxseed and Perindopril in the Prevention of Doxorubicin and Trastuzumab-Induced Cardiotoxicity in C57Bl/6 Mice. Current Oncology. MDPI AG; 2022; 29:2941-2953 10.3390/curroncol29050241
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Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways
Cite
Li S, Liu H, Lin Z, Li Z, Chen Y, Chen B, et al. Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways. Phytomedicine. Elsevier BV; 2022; 101:154105 10.1016/j.phymed.2022.154105
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Diet impacts triple‐negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin‐mediated cardiac dysfunction
Cite
Ramirez MU, Clear KYJ, Cornelius Z, Bawaneh A, Feliz‐Mosquea YR, Wilson AS, et al. Diet impacts triple‐negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin‐mediated cardiac dysfunction. Physiological Reports. Wiley; 2022; 10 10.14814/phy2.15192
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Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study
Cite
Greenlee H, Iribarren C, Rana JS, Cheng R, Nguyen-Huynh M, Rillamas-Sun E, et al. Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2022; 10.1200/jco.21.01736
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Abstract P5-18-12: Cardioprotective effects of walnuts against aromatase inhibitor: Pilot study in a zebrafish model
Cite
Hilakivi-Clarke L, Da Silva JL, Blaes A, Hoeppner L. Abstract P5-18-12: Cardioprotective effects of walnuts against aromatase inhibitor: Pilot study in a zebrafish model. Cancer Research. American Association for Cancer Research (AACR); 2022; 82:P5-18-12-P5-18-12 10.1158/1538-7445.sabcs21-p5-18-12
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Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62–Keap1–Nrf2 pathway
Cite
Jia Y, Guo H, Cheng X, Zhang Y, Si M, Shi J, et al. Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62–Keap1–Nrf2 pathway. Food & Function. Royal Society of Chemistry (RSC); 2022; 10.1039/d2fo00298a
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Natural Polysaccharide β-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress
Cite
Wang X, Ji Y, Jin D, Qi J, Hou X, Zhao W, et al. Natural Polysaccharide β-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress. Nutrients. MDPI AG; 2022; 14:906 10.3390/nu14040906
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Trends in heart disease mortality among breast cancer survivors in the US, 1975–2017
Cite
Vo JB, Ramin C, Barac A, Berrington de Gonzalez A, Veiga L. Trends in heart disease mortality among breast cancer survivors in the US, 1975–2017. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2022; 10.1007/s10549-022-06515-5
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Prevention of doxorubicin-induced experimental cardiotoxicity by Nigella sativa in rats
Cite
Adıyaman MŞ, Adıyaman ÖA, Dağlı AF, Karahan MZ, Dağlı MN. Prevention of doxorubicin-induced experimental cardiotoxicity by Nigella sativa in rats. Revista Portuguesa de Cardiologia. Elsevier BV; 2022; 10.1016/j.repc.2020.12.015
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Use of beta‐blockers and risk of contralateral breast cancer
Cite
Gottschau M, Bens A, Friis S, Cronin‐Fenton D, Aalborg GL, Jensen M, et al. Use of beta‐blockers and risk of contralateral breast cancer. International Journal of Cancer. Wiley; 2022; 10.1002/ijc.33923
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Letrozole Accelerates Metabolic Remodeling through Activation of Glycolysis in Cardiomyocytes: A Role beyond Hormone Regulation
Cite
Heo JH, Lee SR, Jo SL, Yang H, Lee HW, Hong E. Letrozole Accelerates Metabolic Remodeling through Activation of Glycolysis in Cardiomyocytes: A Role beyond Hormone Regulation. International Journal of Molecular Sciences. MDPI AG; 2022; 23:547 10.3390/ijms23010547
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Overexpression of Neuron-Derived Orphan Receptor 1 (NOR-1) Rescues Cardiomyocytes from Cell Death and Improves Viability after Doxorubicin Induced Stress
Cite
Berg P, Hansson ÅML, Røsand Ø, Marwarha G, Høydal MA. Overexpression of Neuron-Derived Orphan Receptor 1 (NOR-1) Rescues Cardiomyocytes from Cell Death and Improves Viability after Doxorubicin Induced Stress. Biomedicines. MDPI AG; 2021; 9:1233 10.3390/biomedicines9091233
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Coenzyme Q10 protects against doxorubicin-induced cardiomyopathy via antioxidant and anti-apoptotic pathway
Cite
Shabaan DA, Mostafa N, El-Desoky MM, Arafat EA. Coenzyme Q10 protects against doxorubicin-induced cardiomyopathy via antioxidant and anti-apoptotic pathway. Tissue Barriers. Informa UK Limited; 2021; 10.1080/21688370.2021.2019504
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Curcumin Ameliorates Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity Via Suppressing Oxidative Stress and Modulating iNOS, NF-κB, and TNF-α in Rats
Cite
Ibrahim Fouad G, Ahmed KA. Curcumin Ameliorates Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity Via Suppressing Oxidative Stress and Modulating iNOS, NF-κB, and TNF-α in Rats. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2021; 10.1007/s12012-021-09710-w
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Cardiac Risk Factors in Black Women With Breast Cancer Undergoing Proton Therapy (PBT): Potential for Increased Therapeutic Gain
Cite
Nichols E, DeCesaris C, Paulosky K, McAvoy S, Ruff S, Vyfhuis M. Cardiac Risk Factors in Black Women With Breast Cancer Undergoing Proton Therapy (PBT): Potential for Increased Therapeutic Gain. International Journal of Radiation Oncology*Biology*Physics. Elsevier BV; 2021; 111:e328 10.1016/j.ijrobp.2021.07.1005
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Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors
Cite
Varghese SS, Johnston WJ, Eekhoudt CR, Keats MR, Jassal DS, Grandy SA. Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors. Current Oncology. MDPI AG; 2021; 28:4139-4156 10.3390/curroncol28050351
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Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity
Cite
Waz S, Matouk AI. Cardioprotective effect of allyl isothiocyanate in a rat model of doxorubicin acute toxicity. Toxicology Mechanisms and Methods. Informa UK Limited; 2021;:1-25 10.1080/15376516.2021.1992064
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Modulation of interaction of BRCA1-RAD51 and BRCA1-AURKA protein complexes by natural metabolites using as possible therapeutic intervention toward cardiotoxic effects of cancer drugs: an in-silico approach
Cite
Tiwari S, Pandey VP, Yadav K, Dwivedi UN. Modulation of interaction of BRCA1-RAD51 and BRCA1-AURKA protein complexes by natural metabolites using as possible therapeutic intervention toward cardiotoxic effects of cancer drugs: an in-silico approach. Journal of Biomolecular Structure and Dynamics. Informa UK Limited; 2021;:1-17 10.1080/07391102.2021.1976278
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A careful reassessment of anthracycline use in curable breast cancer
Cite
Hurvitz SA, McAndrew NP, Bardia A, Press MF, Pegram M, Crown JP, et al. A careful reassessment of anthracycline use in curable breast cancer. npj Breast Cancer. Springer Science and Business Media LLC; 2021; 7 10.1038/s41523-021-00342-5
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Association between cardiac autonomic modulation and sedentary behavior in breast cancer survivors: a 12-month cohort study
Cite
Palma MR, Tebar WR, Vanderlei LCM, Fregonesi CEPT, Ribeiro FE, Caldeira DT, et al. Association between cardiac autonomic modulation and sedentary behavior in breast cancer survivors: a 12-month cohort study. Supportive Care in Cancer. Springer Science and Business Media LLC; 2021; 10.1007/s00520-021-06602-1
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The Potential protective role of astaxanthin on doxorubicin-induced cardiac toxicity in rats
Cite
Derias MSM, Sabaa AERFA, Osman AEMMA, Mohamed AEA, Abou-bakr Darwish DA. The Potential protective role of astaxanthin on doxorubicin-induced cardiac toxicity in rats. QJM: An International Journal of Medicine. Oxford University Press (OUP); 2021; 114 10.1093/qjmed/hcab117.003
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Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating Nuclear factor - like 2 and Sirtuin 2 signaling pathways
Cite
Deng J, Huang M, Wu H. Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating Nuclear factor - like 2 and Sirtuin 2 signaling pathways. Bioengineered. Informa UK Limited; 2021; 10.1080/21655979.2021.1985299
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Reverse cardio-oncology: Exploring the effects of cardiovascular disease on cancer pathogenesis
Cite
Koelwyn GJ, Aboumsallem JP, Moore KJ, de Boer RA. Reverse cardio-oncology: Exploring the effects of cardiovascular disease on cancer pathogenesis. Journal of Molecular and Cellular Cardiology. Elsevier BV; 2021; 10.1016/j.yjmcc.2021.09.008
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523Use of beta blockers and death from breast cancer in New Zealand breast cancer patients
Cite
Scott O, TinTin S, Cavadino A, Elwood M. 523Use of beta blockers and death from breast cancer in New Zealand breast cancer patients. International Journal of Epidemiology. Oxford University Press (OUP); 2021; 50 10.1093/ije/dyab168.587
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Cognitive Dysfunction after Heart Disease: A Manifestation of the Heart-Brain Axis
Cite
Xu C, Tao X, Ma X, Zhao R, Cao Z. Cognitive Dysfunction after Heart Disease: A Manifestation of the Heart-Brain Axis. Oxidative Medicine and Cellular Longevity. Hindawi Limited; 2021; 2021:1-10 10.1155/2021/4899688
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Acute toxicity and tolerability of anthracycline-based chemotherapy regimens in older versus younger patients with breast cancer: real-world data
Cite
Monteiro AR, Garcia AR, Póvoa S, Soares RF, Macedo F, Pereira TC, et al. Acute toxicity and tolerability of anthracycline-based chemotherapy regimens in older versus younger patients with breast cancer: real-world data. Supportive Care in Cancer. Springer Science and Business Media LLC; 2020; 29:2347-2353 10.1007/s00520-020-05766-6
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Antihypertensive medications and risks of recurrence and mortality in luminal, triple-negative, and HER2-overexpressing breast cancer
Cite
Lorona NC, Cook LS, Tang MC, Hill DA, Wiggins CL, Li CI. Antihypertensive medications and risks of recurrence and mortality in luminal, triple-negative, and HER2-overexpressing breast cancer. Cancer Causes & Control. Springer Science and Business Media LLC; 2021; 10.1007/s10552-021-01485-3
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Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
Cite
Abdulkareem Aljumaily SA, Demir M, Elbe H, Yigitturk G, Bicer Y, Altinoz E. Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats. Environmental Science and Pollution Research. Springer Science and Business Media LLC; 2021; 10.1007/s11356-021-15409-w
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Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo
Cite
Tang S, Kan J, Sun R, Cai H, Hong J, Jin C, et al. Anthocyanins from purple sweet potato alleviate doxorubicin‐induced cardiotoxicity in vitro and in vivo. Journal of Food Biochemistry. Wiley; 2021; 10.1111/jfbc.13869
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Aromatase inhibitors use and risk for cardiovascular disease in breast cancer patients: A population-based cohort study
Cite
Sund M, Garcia-Argibay M, Garmo H, Ahlgren J, Wennstig A, Fredriksson I, et al. Aromatase inhibitors use and risk for cardiovascular disease in breast cancer patients: A population-based cohort study. The Breast. Elsevier BV; 2021; 59:157-164 10.1016/j.breast.2021.07.004
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In Vivo and In Vitro Protective Effects of Rosmarinic Acid against Doxorubicin-Induced Cardiotoxicity
Cite
Rahbardar MG, Eisvand F, Rameshrad M, Razavi BM, Hosseinzadeh H. In Vivo and In Vitro Protective Effects of Rosmarinic Acid against Doxorubicin-Induced Cardiotoxicity. Nutrition and Cancer. Informa UK Limited; 2021;:1-15 10.1080/01635581.2021.1931362
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Antioxidant, anti-inflammatory and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
Cite
ALJUMAILY SAA, Demir M, Elbe H, Yigitturk G, Bicer Y, Altinoz E. Antioxidant, anti-inflammatory and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats. Research Square Platform LLC; 2021; 10.21203/rs.3.rs-418902/v1
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Incidence of cardiotoxicity and validation of the Heart Failure Association-International Cardio-Oncology Society risk stratification tool in patients treated with trastuzumab for HER2-positive early breast cancer
Cite
Battisti NML, Andres MS, Lee KA, Ramalingam S, Nash T, Mappouridou S, et al. Incidence of cardiotoxicity and validation of the Heart Failure Association-International Cardio-Oncology Society risk stratification tool in patients treated with trastuzumab for HER2-positive early breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-021-06192-w
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Morphine Deteriorates Cisplatin-Induced Cardiotoxicity in Rats and Induces Dose-Dependent Cisplatin Chemoresistance in MCF-7 Human Breast Cancer Cells
Cite
El-Sheikh AAK, Khired Z. Morphine Deteriorates Cisplatin-Induced Cardiotoxicity in Rats and Induces Dose-Dependent Cisplatin Chemoresistance in MCF-7 Human Breast Cancer Cells. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2021; 10.1007/s12012-021-09646-1
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Beta-blockers use and risk of breast cancer in women with hypertension
Cite
Zheng G, Sundquist J, Sundquist K, Ji J. Beta-blockers use and risk of breast cancer in women with hypertension. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2021;:cebp.1599.2020 10.1158/1055-9965.epi-20-1599
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High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT
Cite
Ansund J, Mijwel S, Bolam KA, Altena R, Wengström Y, Rullman E, et al. High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT. Cardio-Oncology. Springer Science and Business Media LLC; 2021; 7 10.1186/s40959-021-00091-1
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Racial and Socioeconomic Disparities in Cardiotoxicity among Women with HER2-Positive Breast Cancer
Cite
Al-Sadawi M, Hussain Y, Copeland-Halperin RS, Tobin JN, Moskowitz CS, Dang CT, et al. Racial and Socioeconomic Disparities in Cardiotoxicity among Women with HER2-Positive Breast Cancer. The American Journal of Cardiology. Elsevier BV; 2021; 10.1016/j.amjcard.2021.02.013
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CAN ANTIOXIDANT VITAMINS AVOID THE DOXORUBICIN CARDIOTOXICITY IN THE BREAST CANCER TREATMENT?
Cite
Lima Cavalcanti ID, Santos Soares JC, de Fátima Ramos dos Santos Medeiros SM, Ferro Cavalcanti IM, de Britto Lira Nogueira MC. CAN ANTIOXIDANT VITAMINS AVOID THE DOXORUBICIN CARDIOTOXICITY IN THE BREAST CANCER TREATMENT?. PharmaNutrition. Elsevier BV; 2021;:100259 10.1016/j.phanu.2021.100259
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Association between physical activity and subsequent cardiovascular disease among 5-year breast cancer survivors
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Kim KH, Choi S, Kim K, Chang J, Kim SM, Kim SR, et al. Association between physical activity and subsequent cardiovascular disease among 5-year breast cancer survivors. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2021; 10.1007/s10549-021-06140-8
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Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study
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Abdel‐Qadir H, Bobrowski D, Zhou L, Austin PC, Calvillo‐Argüelles O, Amir E, et al. Statin Exposure and Risk of Heart Failure After Anthracycline‐ or Trastuzumab‐Based Chemotherapy for Early Breast Cancer: A Propensity Score‒Matched Cohort Study. Journal of the American Heart Association. Ovid Technologies (Wolters Kluwer Health); 2021; 10.1161/jaha.119.018393
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Ouabain and Digoxin Activate the Proteasome and the Degradation of the ERα in Cells Modeling Primary and Metastatic Breast Cancer
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Busonero C, Leone S, Bianchi F, Maspero E, Fiocchetti M, Palumbo O, et al. Ouabain and Digoxin Activate the Proteasome and the Degradation of the ERα in Cells Modeling Primary and Metastatic Breast Cancer. Cancers. MDPI AG; 2020; 12:3840 10.3390/cancers12123840
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Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage
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Plasma Magnesium Concentrations and Risk of Incident Cancer in Adults with Hypertension: A Nested Case-Control Study
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Lin T, Bi C, Song Y, Guo H, Liu L, Zhou Z, et al. Plasma Magnesium Concentrations and Risk of Incident Cancer in Adults with Hypertension: A Nested Case-Control Study. Annals of Nutrition and Metabolism. S. Karger AG; 2020;:1-9 10.1159/000510214
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Angiotensin Receptor Blockers Associated with Improved Breast Cancer Survival—A Nationwide Cohort Study from Finland
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The Influence of Pre-Existing Beta-Blockers Use on Survival Outcomes in HER2 Positive Advanced Breast Cancer: Pooled Analysis of Clinical Trial Data
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Risk of heart failure after systemic treatment for early breast cancer: results of a cohort study
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Jacobse JN, Schaapveld M, Boekel NB, Hooning MJ, Jager A, Baaijens MHA, et al. Risk of heart failure after systemic treatment for early breast cancer: results of a cohort study. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 10.1007/s10549-020-05930-w
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Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner
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Cardioprotective effect of grape polyphenol extract against doxorubicin induced cardiotoxicity
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Side effects of adjuvant chemotherapy and their impact on outcome in elderly breast cancer patients: a cohort study
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Zanuso V, Fregoni V, Gervaso L. Side effects of adjuvant chemotherapy and their impact on outcome in elderly breast cancer patients: a cohort study. Future Science OA. Future Science Ltd; 2020;:FSO617 10.2144/fsoa-2020-0076
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Myocardial infarction promotes breast cancer recurrence
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Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling
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Myocardial infarction accelerates breast cancer via innate immune reprogramming
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Exercise as a diagnostic and therapeutic tool for preventing cardiovascular morbidity in breast cancer patients– the BReast cancer EXercise InTervention (BREXIT) trial protocol
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Foulkes SJ, Howden EJ, Antill Y, Loi S, Salim A, Haykowsky MJ, et al. Exercise as a diagnostic and therapeutic tool for preventing cardiovascular morbidity in breast cancer patients– the BReast cancer EXercise InTervention (BREXIT) trial protocol. BMC Cancer. Springer Science and Business Media LLC; 2020; 20 10.1186/s12885-020-07123-6
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The Cardioprotective Role of Flaxseed in the Prevention of Doxorubicin- and Trastuzumab-Mediated Cardiotoxicity in C57BL/6 Mice
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Asselin CY, Lam A, Cheung DYC, Eekhoudt CR, Zhu A, Mittal I, et al. The Cardioprotective Role of Flaxseed in the Prevention of Doxorubicin- and Trastuzumab-Mediated Cardiotoxicity in C57BL/6 Mice. The Journal of Nutrition. Oxford University Press (OUP); 2020; 150:2353-2363 10.1093/jn/nxaa144
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A Polyphenol-Rich Muscadine Grape Extract Inhibits HER + Breast Cancer and Protects Against Trastuzumab-Induced Cardiotoxicity
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Cumulative incidence of chemotherapy-induced cardiotoxicity during a 2-year follow-up period in breast cancer patients
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Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects
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Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro
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Agonist Effects of Propranolol on Non-Tumor Human Breast Cells
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Coenzyme Q10 in association with metabolism-related AMPK/PFKFB3 and angiogenic VEGF/VEGFR2 genes in breast cancer patients
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Cardiac mortality after radiotherapy, chemotherapy and endocrine therapy for breast cancer: Cohort study of 2 million women from 57 cancer registries in 22 countries
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Exercise Intolerance in Anthracycline‐Treated Breast Cancer Survivors: The Role of Skeletal Muscle Bioenergetics, Oxygenation, and Composition
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Beaudry RI, Kirkham AA, Thompson RB, Grenier JG, Mackey JR, Haykowsky MJ. Exercise Intolerance in Anthracycline‐Treated Breast Cancer Survivors: The Role of Skeletal Muscle Bioenergetics, Oxygenation, and Composition. The Oncologist. Wiley; 2020; 25 10.1634/theoncologist.2019-0777
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Anticoagulants and Breast Cancer Survival: A Nationwide Cohort Study
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Association of body mass index and cardiotoxicity related to anthracyclines and trastuzumab in early breast cancer: French CANTO cohort study
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Causes of death after breast cancer diagnosis: A US population‐based analysis
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The role of melatonin on doxorubicin-induced cardiotoxicity: A systematic review
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Evidence of β-blockers drug repurposing for the treatment of triple negative breast cancer: A systematic review
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Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways
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Coenzyme Q10 Cardioprotective Effects Against Doxorubicin-Induced Cardiotoxicity in Wistar Rat
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Verification of the effects of calcium channel blockers on the immune microenvironment of breast cancer
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Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer
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Race differences in cardiovascular disease and breast cancer mortality among US women diagnosed with invasive breast cancer
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Cardioprotective Effect of Marine Astaxanthin on Doxorubicin-Induced Cardiotoxicity in Normal Rats
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Beta blockade as adjunctive breast cancer therapy: A review
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Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats
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Milk and kefir maintain aspects of health during doxorubicin treatment in rats
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AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis
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Cardioprotective Effect of Statins in Patients With HER2-Positive Breast Cancer Receiving Trastuzumab Therapy
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A real-world study of cardiac events in > 3700 patients with HER2-positive early breast cancer treated with trastuzumab: final analysis of the OHERA study
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β‑blockers inhibit the viability of breast cancer cells by regulating the ERK/COX‑2 signaling pathway and the drug response is affected by ADRB2 single‑nucleotide polymorphisms
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Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS‑mediated PI3K/AKT signaling pathway
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Wild edible onions — Allium flavum and Allium carinatum — successfully prevent adverse effects of chemotherapeutic drug doxorubicin
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Long term adjuvant endocrine therapy and risk of cardiovascular disease in female breast cancer survivors: systematic review
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The effect of rutin on cisplatin-induced oxidative cardiac damage in rats
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Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients
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Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?
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Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model
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Incidence and risk factors for congestive heart failure in patients with early breast cancer who received anthracycline and/or trastuzumab: a big data analysis of the Korean Health Insurance Review and Assessment service database
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Effects of anthracycline, cyclophosphamide and taxane chemotherapy on QTc measurements in patients with breast cancer
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Sulforaphane potentiates anticancer effects of doxorubicin and attenuates its cardiotoxicity in a breast cancer model
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Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity
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The risk of cardiovascular disease following breast cancer by Framingham risk score
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Quercetin enhances chemotherapeutic effect of doxorubicin against human breast cancer cells while reducing toxic side effects of it
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Long-Term Follow-Up of Cardiac Function and Quality of Life for Patients in NSABP Protocol B-31/NRG Oncology: A Randomized Trial Comparing the Safety and Efficacy of Doxorubicin and Cyclophosphamide (AC) Followed by Paclitaxel With AC Followed by Paclitaxel and Trastuzumab in Patients With Node-Positive Breast Cancer With Tumors Overexpressing Human Epidermal Growth Factor Receptor 2
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Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly- N -acetyl glucosamine nanomatrix in mice bearing solid Ehrlish carcinoma
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Calcium channel blockers and breast cancer incidence: An updated systematic review and meta-analysis of the evidence
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Use of Antihypertensive Medications and Risk of Adverse Breast Cancer Outcomes in a SEER–Medicare Population
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Beta blockers and improved progression-free survival in patients with advanced HER2 negative breast cancer: a retrospective analysis of the ROSE/TRIO-012 study
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Use of Calcium Channel Blockers and Breast Cancer Risk in the Women's Health Initiative
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Protective effects of acute exercise prior to doxorubicin on cardiac function of breast cancer patients: A proof-of-concept RCT
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Cardiac glycosides use and the risk and mortality of cancer; systematic review and meta-analysis of observational studies
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Beta blockers and improved progression-free survival in patients with advanced HER2 negative breast cancer: a retrospective analysis of the ROSE/TRIO-012 study
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Anthracyclines induce early changes in left ventricular systolic and diastolic function: A single centre study
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Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy
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Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis
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The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
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AFRICAN AMERICAN RACE IS A CORRELATE OF HEART FAILURE IN BREAST CANCER SURVIVORS: A STUDY OF 26,347 WOMEN IDENTIFIED WITH BREAST CANCER FROM 1973-2007
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Long-term toxic effects of adjuvant chemotherapy in breast cancer
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Azim H, de Azambuja E, Colozza M, Bines J, Piccart M. Long-term toxic effects of adjuvant chemotherapy in breast cancer. Annals of Oncology. Elsevier BV; 2011; 22:1939-1947 10.1093/annonc/mdq683
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Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity
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El-Demerdash E, Ali AA, El-Taher DE, Hamada FM. Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity. Journal of Pharmacy and Pharmacology. Wiley; 2011; 64:344-352 10.1111/j.2042-7158.2011.01413.x
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Naproxen aggravates doxorubicin-induced cardiomyopathy in rats
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Pathan R, Singh B, Pillai K, Dubey K. Naproxen aggravates doxorubicin-induced cardiomyopathy in rats. Indian Journal of Pharmacology. Medknow; 2010; 42:44 10.4103/0253-7613.62411
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Grape Seed and Skin Extract Protects Against Acute Chemotherapy Toxicity induced by Doxorubicin in Rat Heart
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Mokni M, Hamlaoui-Guesmi S, Amri M, Marzouki L, Limam F, Aouani E. Grape Seed and Skin Extract Protects Against Acute Chemotherapy Toxicity induced by Doxorubicin in Rat Heart. Cardiovascular Toxicology. Springer Science and Business Media LLC; 2012; 12:158-165 10.1007/s12012-012-9155-1
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Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats
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Swamy A, Gulliaya S, Thippeswamy A, Koti B, Manjula D. Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats. Indian Journal of Pharmacology. Medknow; 2012; 44:73 10.4103/0253-7613.91871
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Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro
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Xiao J, Sun G, Sun B, Wu Y, He L, Wang X, et al. Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. Toxicology. Elsevier BV; 2012; 292:53-62 10.1016/j.tox.2011.11.018
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Adjuvant Trastuzumab in HER2-Positive Breast Cancer
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Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M, et al. Adjuvant Trastuzumab in HER2-Positive Breast Cancer. New England Journal of Medicine. Massachusetts Medical Society; 2011; 365:1273-1283 10.1056/nejmoa0910383
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Pathology of late-onset anthracycline cardiomyopathy
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Bernaba BN, Chan JB, Lai CK, Fishbein MC. Pathology of late-onset anthracycline cardiomyopathy. Cardiovascular Pathology. Elsevier BV; 2010; 19:308-311 10.1016/j.carpath.2009.07.004
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Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy
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Nodari S, Triggiani M, Campia U, Manerba A, Milesi G, Cesana BM, et al. Effects of n-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Functional Capacity in Patients With Dilated Cardiomyopathy. Journal of the American College of Cardiology. Elsevier BV; 2011; 57:870-879 10.1016/j.jacc.2010.11.017
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Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology
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Eschenhagen T, Force T, Ewer MS, de Keulenaer GW, Suter TM, Anker SD, et al. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure. Wiley; 2011; 13:1-10 10.1093/eurjhf/hfq213
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Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation
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Konishi M, Haraguchi G, Ohigashi H, Ishihara T, Saito K, Nakano Y, et al. Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation. Cardiovascular Research. Oxford University Press (OUP); 2010; 89:309-319 10.1093/cvr/cvq335
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Early identification of trastuzumab-related cardiotoxicity with speckle-tracking echocardiography.
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Maurea N, De Lorenzo C, Coppola C, Ragone G, Di Pietro E, Schiattarella G, et al. Early identification of trastuzumab-related cardiotoxicity with speckle-tracking echocardiography.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2010; 28:e11096-e11096 10.1200/jco.2010.28.15_suppl.e11096
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Abstract 3223: Severe dietary restriction enhances cancer treatment: Protecting normal cells and sensitizing malignant cells to chemotherapy by fasting
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Lee C, Safdie F, Raffaghello L, Wei M, Longo V. Abstract 3223: Severe dietary restriction enhances cancer treatment: Protecting normal cells and sensitizing malignant cells to chemotherapy by fasting. Cellular and Molecular Biology. American Association for Cancer Research; 2010; 10.1158/1538-7445.am10-3223