Tag: androgens
Androgens: Steroid hormones that influence the development and maintenance of masculine characteristics by binding to androgen receptors. Examples include testosterone, androstenedione, dehydroepiandrosterone (DHEA), and DHEA sulfate.
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Nutritional Metabolomics in Diet–Breast Cancer Relations: Current Research, Challenges, and Future Directions—A Review
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Vahid F, Hajizadeghan K, Khodabakhshi A. Nutritional Metabolomics in Diet–Breast Cancer Relations: Current Research, Challenges, and Future Directions—A Review. Biomedicines. MDPI AG; 2023; 11:1845 10.3390/biomedicines11071845
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The Other Side of the Coin: May Androgens Have a Role in Breast Cancer Risk?
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Chiodo C, Morelli C, Cavaliere F, Sisci D, Lanzino M. The Other Side of the Coin: May Androgens Have a Role in Breast Cancer Risk?. International Journal of Molecular Sciences. MDPI AG; 2021; 23:424 10.3390/ijms23010424
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Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations
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Zamir A, Ben-Zeev T, Hoffman JR. Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations. Nutrients. MDPI AG; 2021; 13:3375 10.3390/nu13103375
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Intrinsic Subtypes and Androgen Receptor Gene Expression in Primary Breast Cancer. A Meta-Analysis
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Cruz-Tapias P, Rubiano W, Rondón-Lagos M, Villegas V, Rangel N. Intrinsic Subtypes and Androgen Receptor Gene Expression in Primary Breast Cancer. A Meta-Analysis. Biology. MDPI AG; 2021; 10:834 10.3390/biology10090834
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(-)-Epicatechin acts as a potent agonist of the membrane androgen receptor, ZIP9 (SLC39A9), to promote apoptosis of breast and prostate cancer cells
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Thomas P, Dong J. (-)-Epicatechin acts as a potent agonist of the membrane androgen receptor, ZIP9 (SLC39A9), to promote apoptosis of breast and prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2021;:105906 10.1016/j.jsbmb.2021.105906
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Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis by epigenetic regulation of MMP9 expression via the AKT/mTOR signaling pathway
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Wu H, Lin J, Liu Y, Chen H, Hsu K, Lin S, et al. Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis by epigenetic regulation of MMP9 expression via the AKT/mTOR signaling pathway. Phytomedicine. Elsevier BV; 2020; 81:153437 10.1016/j.phymed.2020.153437
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Role of androgen receptor expression in early stage ER+/PgR−/HER2– breast cancer
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Tagliaferri B, Quaquarini E, Palumbo R, Balletti E, Presti D, Malovini A, et al. Role of androgen receptor expression in early stage ER+/PgR−/HER2– breast cancer. Therapeutic Advances in Medical Oncology. SAGE Publications; 2020; 12:175883592095835 10.1177/1758835920958355
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Triple-negative pleomorphic lobular carcinoma and expression of androgen receptor: Personal case series and review of the literature
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Taniguchi K, Takada S, Omori M, Igawa T, Nishimura MF, Morito T, et al. Triple-negative pleomorphic lobular carcinoma and expression of androgen receptor: Personal case series and review of the literature. PLOS ONE. Public Library of Science (PLoS); 2020; 15:e0235790 10.1371/journal.pone.0235790
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Abstract B105: The impact of ancestry on mutational and immune signatures in triple-negative breast cancers
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Hughley RW, Yates C, Polak P. Abstract B105: The impact of ancestry on mutational and immune signatures in triple-negative breast cancers. Poster Presentations - Proffered Abstracts. American Association for Cancer Research; 2020; 10.1158/1538-7755.disp19-b105
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Quadruple negative breast cancer
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Huang M, Wu J, Ling R, Li N. Quadruple negative breast cancer. Breast Cancer. Springer Science and Business Media LLC; 2020; 27:527-533 10.1007/s12282-020-01047-6
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Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy
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Jongen L, Floris G, Wildiers H, Claessens F, Richard F, Laenen A, et al. Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2019; 176:699-708 10.1007/s10549-019-05252-6
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Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses’ Health Studies
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Kensler KH, Poole EM, Heng YJ, Collins LC, Glass B, Beck AH, et al. Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses’ Health Studies. JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2018; 111:700-708 10.1093/jnci/djy173
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Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?
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Bronte G, Rocca A, Ravaioli S, Puccetti M, Tumedei MM, Scarpi E, et al. Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4239-3
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The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome
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Ricciardelli C, Bianco-Miotto T, Jindal S, Butler LM, Leung S, McNeil CM, et al. The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome. Clinical Cancer Research. American Association for Cancer Research (AACR); 2018; 24:2328-2341 10.1158/1078-0432.ccr-17-1199
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HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors
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Daemen A, Manning G. HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors. Breast Cancer Research. Springer Science and Business Media LLC; 2018; 20 10.1186/s13058-018-0933-y
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Current smoking is associated with a larger waist circumference and a more androgenic profile in young healthy women from high-risk breast cancer families
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Ellberg C, Olsson H, Jernström H. Current smoking is associated with a larger waist circumference and a more androgenic profile in young healthy women from high-risk breast cancer families. Cancer Causes & Control. Springer Science and Business Media LLC; 2018; 29:243-251 10.1007/s10552-017-0999-3
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The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer
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Wellberg EA, Checkley LA, Giles ED, Johnson SJ, Oljira R, Wahdan-Alaswad R, et al. The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer. Hormones and Cancer. Springer Science and Business Media LLC; 2017; 8:269-285 10.1007/s12672-017-0302-9
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Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer
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Barton VN, Christenson JL, Gordon MA, Greene LI, Rogers TJ, Butterfield K, et al. Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer. Cancer Research. American Association for Cancer Research (AACR); 2017; 77:3455-3466 10.1158/0008-5472.can-16-3240
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Abstract B20: Targeting androgen receptor and vitamin D receptor in triple negative breast cancers
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Thakkar A, Wang B, Picon-Ruiz M, Ince T. Abstract B20: Targeting androgen receptor and vitamin D receptor in triple negative breast cancers. Targeting Epigenetics. American Association for Cancer Research; 2017; 10.1158/1557-3265.pmccavuln16-b20
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A novel approach to breast cancer prevention: reducing excessive ovarian androgen production in elderly women
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Secreto G, Sieri S, Agnoli C, Grioni S, Muti P, Zumoff B, et al. A novel approach to breast cancer prevention: reducing excessive ovarian androgen production in elderly women. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 158:553-561 10.1007/s10549-016-3901-1
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Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer
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Zhu A, Li Y, Song W, Xu Y, Yang F, Zhang W, et al. Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer. Cellular Physiology and Biochemistry. S. Karger AG; 2016; 38:1003-1014 10.1159/000443052
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Androgen receptor and antiandrogen therapy in male breast cancer
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Di Lauro L, Barba M, Pizzuti L, Vici P, Sergi D, Di Benedetto A, et al. Androgen receptor and antiandrogen therapy in male breast cancer. Cancer Letters. Elsevier BV; 2015; 368:20-25 10.1016/j.canlet.2015.07.040
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Role of Androgen and Estrogen Receptors as Prognostic and Potential Predictive Markers of Ductal Carcinoma in Situ of the Breast
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Tumedei MM, Silvestrini R, Ravaioli S, Massa I, Maltoni R, Rocca A, et al. Role of Androgen and Estrogen Receptors as Prognostic and Potential Predictive Markers of Ductal Carcinoma in Situ of the Breast. The International Journal of Biological Markers. SAGE Publications; 2015; 30:425-428 10.5301/jbm.5000163
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Androgen Receptor (AR), E-Cadherin, and Ki-67 as Emerging Targets and Novel Prognostic Markers in Triple-Negative Breast Cancer (TNBC) Patients
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Ricciardi GRR, Adamo B, Ieni A, Licata L, Cardia R, Ferraro G, et al. Androgen Receptor (AR), E-Cadherin, and Ki-67 as Emerging Targets and Novel Prognostic Markers in Triple-Negative Breast Cancer (TNBC) Patients. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0128368 10.1371/journal.pone.0128368
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Expression of androgen receptor in inflammatory breast cancer and its clinical relevance
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Gong Y, Wei W, Wu Y, Ueno NT, Huo L. Expression of androgen receptor in inflammatory breast cancer and its clinical relevance. Cancer. Wiley; 2014; 120:1775-1779 10.1002/cncr.28667
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Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort
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Elebro K, Butt S, Dorkhan M, Jernström H, Borgquist S. Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort. Cancer Causes & Control. Springer Science and Business Media LLC; 2014; 25:945-957 10.1007/s10552-014-0394-2
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Androgen Receptor Expression and Outcomes in Early Breast Cancer: A Systematic Review and Meta-Analysis
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Vera-Badillo FE, Templeton AJ, de Gouveia P, Diaz-Padilla I, Bedard PL, Al-Mubarak M, et al. Androgen Receptor Expression and Outcomes in Early Breast Cancer: A Systematic Review and Meta-Analysis. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2013; 106:djt319-djt319 10.1093/jnci/djt319
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Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up
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Zhang X, Tworoger SS, Eliassen AH, Hankinson SE. Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2013; 137:883-892 10.1007/s10549-012-2391-z
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Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation
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Sirianni R, Capparelli C, Chimento A, Panza S, Catalano S, Lanzino M, et al. Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation. Molecular and Cellular Endocrinology. Elsevier BV; 2012; 363:100-110 10.1016/j.mce.2012.08.002
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Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial
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Campbell KL, Foster-Schubert KE, Alfano CM, Wang C, Wang C, Duggan CR, et al. Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2012; 30:2314-2326 10.1200/jco.2011.37.9792
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Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women
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Lee CC, Bloem CJ, Kasa-Vubu JZ, Liang L. Effect of oral phytoestrogen on androgenicity and insulin sensitivity in postmenopausal women. Diabetes, Obesity and Metabolism. Wiley; 2011; 14:315-319 10.1111/j.1463-1326.2011.01532.x
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Oestrogenic and androgenic activity of triclosan in breast cancer cells
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Gee RH, Charles A, Taylor N, Darbre PD. Oestrogenic and androgenic activity of triclosan in breast cancer cells. Journal of Applied Toxicology. Wiley; 2007; 28:78-91 10.1002/jat.1316
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Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC)
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Ruder EH, Hartman TJ, Rovine MJ, Dorgan JF. Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC). Cancer Causes & Control. Springer Science and Business Media LLC; 2010; 21:1379-1386 10.1007/s10552-010-9565-y
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Analgesic Use and Sex Steroid Hormone Concentrations in Postmenopausal Women
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Gates MA, Tworoger SS, Eliassen AH, Missmer SA, Hankinson SE. Analgesic Use and Sex Steroid Hormone Concentrations in Postmenopausal Women. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2010; 19:1033-1041 10.1158/1055-9965.epi-09-0975
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Physical Activity and Postmenopausal Breast Cancer: Proposed Biologic Mechanisms and Areas for Future Research
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Neilson HK, Friedenreich CM, Brockton NT, Millikan RC. Physical Activity and Postmenopausal Breast Cancer: Proposed Biologic Mechanisms and Areas for Future Research. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2009; 18:11-27 10.1158/1055-9965.epi-08-0756
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Circulating Steroid Hormone Levels and Risk of Breast Cancer for Postmenopausal Women
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Baglietto L, Severi G, English DR, Krishnan K, Hopper JL, McLean C, et al. Circulating Steroid Hormone Levels and Risk of Breast Cancer for Postmenopausal Women. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2010; 19:492-502 10.1158/1055-9965.epi-09-0532
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Recreational Physical Activity and Steroid Hormone Levels in Postmenopausal Women
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Bertone-Johnson ER, Tworoger SS, Hankinson SE. Recreational Physical Activity and Steroid Hormone Levels in Postmenopausal Women. American Journal of Epidemiology. Oxford University Press (OUP); 2009; 170:1095-1104 10.1093/aje/kwp254
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Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils
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Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils. New England Journal of Medicine. Massachusetts Medical Society; 2007; 356:479-485 10.1056/nejmoa064725
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Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances
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Lu Q, Arteaga JR, Zhang Q, Huerta S, Go VLW, Heber D. Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances. The Journal of Nutritional Biochemistry. Elsevier BV; 2005; 16:23-30 10.1016/j.jnutbio.2004.08.003