Tag: HER2HRpos

HER2 positive, HR positive: Hormone receptor positive breast cancer that overexpresses the HER2 gene (ER+/PR+/HER2+, triple positive).

Articles

News

01/20/13: Some BC types have up to 11% locoregional recurrence after mastectomy
04/12/12: Five-year prognosis by breast cancer subtype

Studies

Apoptotic effect of melatonin on ER-positive breast cancer cell lines: ADGRL4 gene expression and promoter methylation Cite
Rajabi A, Safaralizadeh R, Saber A, Pourmahdi M, Teimourian S, Montazeri V, et al. Apoptotic effect of melatonin on ER-positive breast cancer cell lines: ADGRL4 gene expression and promoter methylation. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2024; 10.1007/s00210-024-03383-2
Differential effects of docosahexaenoic acid (DHA) and linoleic acid (LA) on miR-101 and miR-342 tumor suppressor microRNAs in Taxol-treated HER2-positive breast cancer cells Cite
Aslan C, Maralbashi S, Shekari N, Javadian M, Shomali N, Kazemi T. Differential effects of docosahexaenoic acid (DHA) and linoleic acid (LA) on miR-101 and miR-342 tumor suppressor microRNAs in Taxol-treated HER2-positive breast cancer cells. Clinical Nutrition ESPEN. Elsevier BV; 2024; 63:502-507 10.1016/j.clnesp.2024.07.007
Dose/Exposure Relationship of Exercise and Distant Recurrence in Primary Breast Cancer Cite
Soldato D, Michiels S, Havas J, Di Meglio A, Pagliuca M, Franzoi MA, et al. Dose/Exposure Relationship of Exercise and Distant Recurrence in Primary Breast Cancer. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2024; 10.1200/jco.23.01959
Abstract PO4-18-03: Combined Treatment with Pyrotinib and Chrysin Synergistically Improve the Autophagy Level in HER2-Positive Breast Cancer by Regulating the miR-16-5p/ZBTB16/G6PD Axis Cite
Luo T, Zhong X, He P, Zheng D, Cheng Y, Zhu K. Abstract PO4-18-03: Combined Treatment with Pyrotinib and Chrysin Synergistically Improve the Autophagy Level in HER2-Positive Breast Cancer by Regulating the miR-16-5p/ZBTB16/G6PD Axis. Cancer Research. American Association for Cancer Research (AACR); 2024; 84:PO4-18-03-PO4-18-03 10.1158/1538-7445.sabcs23-po4-18-03
Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells Cite
Maralbashi S, Aslan C, Kahroba H, Asadi M, Soltani-Zangbar MS, Haghnavaz N, et al. Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells. BMC Nutrition. Springer Science and Business Media LLC; 2024; 10 10.1186/s40795-024-00844-y
Long-term cadmium exposure induces epithelial-mesenchymal transition in breast cancer cells by activating CYP1B1-mediated glutamine metabolic reprogramming in BT474 cells and MMTV-Erbb2 mice Cite
Li J, Gao P, Qin M, Wang J, Luo Y, Deng P, et al. Long-term cadmium exposure induces epithelial-mesenchymal transition in breast cancer cells by activating CYP1B1-mediated glutamine metabolic reprogramming in BT474 cells and MMTV-Erbb2 mice. Science of The Total Environment. Elsevier BV; 2024; 918:170773 10.1016/j.scitotenv.2024.170773
Clinicopathological differences and survival benefit in ER+/PR+/HER2+ vs ER+/PR−/HER2+ breast cancer subtypes Cite
Ding W, Ye D, Chen H, Lin Y, Li Z, Tu C. Clinicopathological differences and survival benefit in ER+/PR+/HER2+ vs ER+/PR−/HER2+ breast cancer subtypes. Breast Cancer. Springer Science and Business Media LLC; 2024; 10.1007/s12282-023-01538-2
Synergistic Anti-Cancer Potential of Phenethyl Isothiocyanate and Curcumin Induces Apoptosis and G2/M Cell Cycle Arrest in HER2-Positive Breast Cancer Cells Cite
Sirigiripeta S, Dokala A, Anupalli R. Synergistic Anti-Cancer Potential of Phenethyl Isothiocyanate and Curcumin Induces Apoptosis and G2/M Cell Cycle Arrest in HER2-Positive Breast Cancer Cells. Cytology and Genetics. Allerton Press; 2023; 57:611-624 10.3103/s0095452723060087
SAT428 The Effects Of Diphenyl Phthalate (DP) On Estrogen Receptor Alpha (ERα;) And Tumor Suppressor Gene (BRCA-1) In Breast Cancer Cells Cite
Whittaker K, Hallman E, Zanib A, Pfiffner S, Yaldo R, Dinda S. SAT428 The Effects Of Diphenyl Phthalate (DP) On Estrogen Receptor Alpha (ERα;) And Tumor Suppressor Gene (BRCA-1) In Breast Cancer Cells. Journal of the Endocrine Society. The Endocrine Society; 2023; 7 10.1210/jendso/bvad114.1059
Epigenetic Silencing of HER2 Expression during Epithelial-Mesenchymal Transition Leads to Trastuzumab Resistance in Breast Cancer Cite
Nami B, Ghanaeian A, Black C, Wang Z. Epigenetic Silencing of HER2 Expression during Epithelial-Mesenchymal Transition Leads to Trastuzumab Resistance in Breast Cancer. Life. MDPI AG; 2021; 11:868 10.3390/life11090868
Time to Completion of Breast Cancer Treatment and Survival Cite
Pratt D, Burneikis T, Tu C, Grobmyer S. Time to Completion of Breast Cancer Treatment and Survival. Annals of Surgical Oncology. Springer Science and Business Media LLC; 2021; 10.1245/s10434-021-10116-9
Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer Cite
Watanabe T, Oba T, Tanimoto K, Shibata T, Kamijo S, Ito K. Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer. PLOS ONE. Public Library of Science (PLoS); 2021; 16:e0252822 10.1371/journal.pone.0252822
Evaluating human epidermal growth factor receptor 2 roles in the efficacy of Tamoxifen treatment in breast cancer, a systematic review Cite
Mansouri S, Mokhtari-Hesari P, Naghavi-al-Hosseini F, Seyednejad SA, Majidzadeh-A K, Moradi-kalbolandi S, et al. Evaluating human epidermal growth factor receptor 2 roles in the efficacy of Tamoxifen treatment in breast cancer, a systematic review. Pharmacological Reports. Springer Science and Business Media LLC; 2021; 10.1007/s43440-021-00237-z
Effect of level of hormone-receptor expression on treatment outcomes of “triple-positive” early-stage breast cancer Cite
Abdel-Razeq H, Edaily S, Iweir S, Salam M, Saleh Y, Sughayer M, et al. Effect of level of hormone-receptor expression on treatment outcomes of “triple-positive” early-stage breast cancer. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2020; 10.1007/s10549-020-05942-6
Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor Cite
Andreani C, Bartolacci C, Wijnant K, Crinelli R, Bianchi M, Magnani M, et al. Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor. Aging. Impact Journals, LLC; 2017; 9:508-523 10.18632/aging.101175
Docosahexaenoic acid (DHA) inhibits pro-angiogenic effects of breast cancer cells via down-regulating cellular and exosomal expression of angiogenic genes and microRNAs Cite
Aslan C, Maralbashi S, Kahroba H, Asadi M, Soltani-Zangbar MS, Javadian M, et al. Docosahexaenoic acid (DHA) inhibits pro-angiogenic effects of breast cancer cells via down-regulating cellular and exosomal expression of angiogenic genes and microRNAs. Life Sciences. Elsevier BV; 2020; 258:118094 10.1016/j.lfs.2020.118094
Co-Treatment with Sulforaphane and Nano-Metformin Molecules Accelerates Apoptosis in HER2+ Breast Cancer Cells by Inhibiting Key Molecules Cite
Keshandehghan A, Nikkhah S, Tahermansouri H, Heidari-Keshel S, Gardaneh M. Co-Treatment with Sulforaphane and Nano-Metformin Molecules Accelerates Apoptosis in HER2+ Breast Cancer Cells by Inhibiting Key Molecules. Nutrition and Cancer. Informa UK Limited; 2019; 72:835-848 10.1080/01635581.2019.1655073
Dark sweet cherry (Prunus avium) phenolics enriched in anthocyanins exhibit enhanced activity against the most aggressive breast cancer subtypes without toxicity to normal breast cells Cite
Lage NN, Layosa MAA, Arbizu S, Chew BP, Pedrosa ML, Mertens-Talcott S, et al. Dark sweet cherry (Prunus avium) phenolics enriched in anthocyanins exhibit enhanced activity against the most aggressive breast cancer subtypes without toxicity to normal breast cells. Journal of Functional Foods. Elsevier BV; 2019; 64:103710 10.1016/j.jff.2019.103710
Folic acid prevents the progesterone-promoted proliferation and migration in breast cancer cell lines Cite
Wang H, Huo Y, Lee W. Folic acid prevents the progesterone-promoted proliferation and migration in breast cancer cell lines. European Journal of Nutrition. Springer Science and Business Media LLC; 2019; 59:2333-2344 10.1007/s00394-019-02077-3
Abstract 296: Trastuzumab sensitizes HER2+ breast cancer to increase efficacy of chemotherapyin vitroandin vivo Cite
Shah A, Jarrett A, Syed A, Yankeelov T, Sorace A. Abstract 296: Trastuzumab sensitizes HER2+ breast cancer to increase efficacy of chemotherapyin vitroandin vivo. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2019; 10.1158/1538-7445.am2019-296
Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment Cite
Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, et al. Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. Cellular Oncology. Springer Science and Business Media LLC; 2019; 42:815-828 10.1007/s13402-019-00464-w
(−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo Cite
Siddique A, Ebrahim H, Akl M, Ayoub N, Goda A, Mohyeldin M, et al. (−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo. Nutrients. MDPI AG; 2019; 11:412 10.3390/nu11020412
Curcumin and paclitaxel induce cell death in breast cancer cell lines Cite
Calaf G, Ponce-Cusi R, Carrion F. Curcumin and paclitaxel induce cell death in breast cancer cell lines. Oncology Reports. Spandidos Publications; 2018; 10.3892/or.2018.6603
Abstract 2683: The olive-based oleocanthal as a dual HER2-MET inhibitor for the control of breast cancer recurrence Cite
Siddique AB, Ebrahim H, Mohyeldin M, Jois SD, Sayed KAE. Abstract 2683: The olive-based oleocanthal as a dual HER2-MET inhibitor for the control of breast cancer recurrence. Cancer Chemistry. American Association for Cancer Research; 2018; 10.1158/1538-7445.am2018-2683
Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells Cite
Chen J, Zhu Y, Zhang W, Peng X, Zhou J, Li F, et al. Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4231-y
An Animal Model of Local Breast Cancer Recurrence in the Setting of Autologous Fat Grafting for Breast Reconstruction Cite
Tsuji W, Valentin JE, Marra KG, Donnenberg AD, Donnenberg VS, Rubin JP. An Animal Model of Local Breast Cancer Recurrence in the Setting of Autologous Fat Grafting for Breast Reconstruction. STEM CELLS Translational Medicine. Wiley; 2017; 7:125-134 10.1002/sctm.17-0062
Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts Cite
Yttersian Sletta K, Tveitarås MK, Lu N, Engelsen AST, Reed RK, Garmann-Johnsen A, et al. Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts. PLOS ONE. Public Library of Science (PLoS); 2017; 12:e0183254 10.1371/journal.pone.0183254
Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2 Cite
Huang Y, Jin Q, Su M, Ji F, Wang N, Zhong C, et al. Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2. Cellular Oncology. Springer Science and Business Media LLC; 2017; 40:537-547 10.1007/s13402-017-0342-8
Risk of mortality of node-negative, ER/PR/HER2 breast cancer subtypes in T1, T2, and T3 tumors Cite
Parise CA, Caggiano V. Risk of mortality of node-negative, ER/PR/HER2 breast cancer subtypes in T1, T2, and T3 tumors. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 165:743-750 10.1007/s10549-017-4383-5
Natural and synthetic progestins enrich cancer stem cell-like cells in hormone-responsive human breast cancer cell populations in vitro Cite
Goyette S, Liang Y, Mafuvadze B, Cook M, Munir M, Hyder S. Natural and synthetic progestins enrich cancer stem cell-like cells in hormone-responsive human breast cancer cell populations in vitro. Breast Cancer: Targets and Therapy. Informa UK Limited; 2017; Volume 9:347-357 10.2147/bctt.s135371
The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment Cite
Ayoub NM, Siddique AB, Ebrahim HY, Mohyeldin MM, El Sayed KA. The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment. European Journal of Pharmacology. Elsevier BV; 2017; 810:100-111 10.1016/j.ejphar.2017.06.019
Piperlongumine downregulates the expression of HER family in breast cancer cells Cite
Jin H, Park J, Kim H, Chang YH, Hong YJ, Park I, et al. Piperlongumine downregulates the expression of HER family in breast cancer cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2017; 486:1083-1089 10.1016/j.bbrc.2017.03.166
Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells Cite
Tseng H, Wang Y, Tzeng Y, Chen D, Liao Y, Chiu H, et al. Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells. The American Journal of Chinese Medicine. World Scientific Pub Co Pte Lt; 2017; 45:337-350 10.1142/s0192415x17500215
Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice Cite
Parris AB, Zhao Q, Howard EW, Zhao M, Ma Z, Yang X. Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice. Journal of Experimental & Clinical Cancer Research. Springer Science and Business Media LLC; 2017; 36 10.1186/s13046-017-0498-0
Cytotoxic activities of five compounds with high polarity in BT-474 breast cancer cell line by NRU and MTT assays Cite
Bacanli M, Anlar H, Basaran N, Basaran A. Cytotoxic activities of five compounds with high polarity in BT-474 breast cancer cell line by NRU and MTT assays. Planta Medica. Georg Thieme Verlag KG; 2016; 81:S1-S381 10.1055/s-0036-1596935
Abstract 3787: Thyroid hormone induced proliferation of breast cancer cell lines: A novel approach to hormone therapy Cite
Jerzak KJ, Cockburn JG, Hassel J, Pritchard KI, Dhesy-Thind SK, Anita B. Abstract 3787: Thyroid hormone induced proliferation of breast cancer cell lines: A novel approach to hormone therapy. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-3787
Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes Cite
Rondón-Lagos M, Rangel N, Di Cantogno LV, Annaratone L, Castellano I, Russo R, et al. Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes. Endocrine-Related Cancer. Bioscientifica; 2016; 23:635-650 10.1530/erc-16-0078
Breast Cancer Mortality among Asian-American Women in California: Variation according to Ethnicity and Tumor Subtype Cite
Parise C, Caggiano V. Breast Cancer Mortality among Asian-American Women in California: Variation according to Ethnicity and Tumor Subtype. Journal of Breast Cancer. Korean Breast Cancer Society; 2016; 19:112 10.4048/jbc.2016.19.2.112
Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells Cite
SEO H, KU JM, CHOI H, CHOI YK, WOO J, KIM M, et al. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells. Oncology Reports. Spandidos Publications; 2016; 36:31-42 10.3892/or.2016.4786
Abstract P1-16-06: Luteolin inhibits progestin-dependent VEGF induction, stem-cell like characteristics, and tumor progression of human breast cancer cells Cite
Hyder S, Cook M, Besch-Williford C, Liang Y. Abstract P1-16-06: Luteolin inhibits progestin-dependent VEGF induction, stem-cell like characteristics, and tumor progression of human breast cancer cells. Poster Session Abstracts. American Association for Cancer Research; 2016; 10.1158/1538-7445.sabcs15-p1-16-06
Abstract P6-12-14: Comparative analysis of breast cancer phenotypes in African American, White American, and African patients- Correlation between African ancestry and triple negative breast cancer Cite
Newman L, Jiagge E, Bensenhaver J, Chitale D, Kleer C, Merajver S, et al. Abstract P6-12-14: Comparative analysis of breast cancer phenotypes in African American, White American, and African patients- Correlation between African ancestry and triple negative breast cancer. Poster Session Abstracts. American Association for Cancer Research; 2016; 10.1158/1538-7445.sabcs15-p6-12-14
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab Cite
Cañas A, López-Sánchez LM, Peñarando J, Valverde A, Conde F, Hernández V, et al. Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Elsevier BV; 2016; 1862:601-610 10.1016/j.bbadis.2016.02.005
Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474) Cite
Mason JK, Fu M, Chen J, Thompson LU. Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474). The Journal of Nutritional Biochemistry. Elsevier BV; 2015; 26:16-23 10.1016/j.jnutbio.2014.08.001
α-Linolenic Acid Reduces Growth of Both Triple Negative and Luminal Breast Cancer Cells in High and Low Estrogen Environments Cite
Wiggins AKA, Kharotia S, Mason JK, Thompson LU. α-Linolenic Acid Reduces Growth of Both Triple Negative and Luminal Breast Cancer Cells in High and Low Estrogen Environments. Nutrition and Cancer. Informa UK Limited; 2015; 67:1001-1009 10.1080/01635581.2015.1053496
Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells Cite
Pan S, Yuan C, Tagmount A, Rudel RA, Ackerman JM, Yaswen P, et al. Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells. Environmental Health Perspectives. Environmental Health Perspectives; 2016; 124:563-569 10.1289/ehp.1409200
Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells Cite
Seo H, Jo J, Ku J, Choi H, Choi Y, Woo J, et al. Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells. Bioscience Reports. Portland Press Ltd.; 2015; 35 10.1042/bsr20150165
Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis Cite
Cook MT, Liang Y, Goyette S, Mafuvadze B, Besch-Williford C, Hyder S. Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis. Tumor Biology. American Association for Cancer Research; 2015; 10.1158/1538-7445.am2015-4159
Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs Cite
Banerjee N, Kim H, Krenek K, Talcott ST, Mertens-Talcott SU. Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs. Nutrition Research. Elsevier BV; 2015; 35:744-751 10.1016/j.nutres.2015.06.002
Abstract P6-01-13: SOX10 and folate receptor alpha are frequently expressed in triple negative and progesterone receptor negative breast cancers Cite
Hoang LL, Qi W, Yu C, Tacha D. Abstract P6-01-13: SOX10 and folate receptor alpha are frequently expressed in triple negative and progesterone receptor negative breast cancers. Poster Session Abstracts. American Association for Cancer Research; 2015; 10.1158/1538-7445.sabcs14-p6-01-13
Growth and gene expression differ over time in alpha-linolenic acid treated breast cancer cells Cite
Wiggins AK, Mason JK, Thompson LU. Growth and gene expression differ over time in alpha-linolenic acid treated breast cancer cells. Experimental Cell Research. Elsevier BV; 2015; 333:147-154 10.1016/j.yexcr.2015.02.020
Anthocyanins potentiate the activity of trastuzumab in human epidermal growth factor receptor 2-positive breast cancer cells in vitro and in vivo Cite
LIU W, XU J, LIU Y, YU X, TANG X, WANG Z, et al. Anthocyanins potentiate the activity of trastuzumab in human epidermal growth factor receptor 2-positive breast cancer cells in vitro and in vivo. Molecular Medicine Reports. Spandidos Publications; 2014; 10:1921-1926 10.3892/mmr.2014.2414
Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models Cite
Akl MR, Ayoub NM, Mohyeldin MM, Busnena BA, Foudah AI, Liu Y, et al. Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e97622 10.1371/journal.pone.0097622
Chronic Morphine Treatment Attenuates Cell Growth of Human BT474 Breast Cancer Cells by Rearrangement of the ErbB Signalling Network Cite
Weingaertner IR, Koutnik S, Ammer H. Chronic Morphine Treatment Attenuates Cell Growth of Human BT474 Breast Cancer Cells by Rearrangement of the ErbB Signalling Network. PLoS ONE. Public Library of Science (PLoS); 2013; 8:e53510 10.1371/journal.pone.0053510
Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines Cite
Woode DR, Aiyer HS, Sie N, Zwart AL, Li L, Seeram NP, et al. Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines. International Journal of Breast Cancer. Hindawi Limited; 2012; 2012:1-11 10.1155/2012/147828
Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation Cite
Banerjee N, Talcott S, Safe S, Mertens-Talcott SU. Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2012; 136:21-34 10.1007/s10549-012-2224-0
High levels of arachidonic acid and peroxisome proliferator-activated receptor-alpha in breast cancer tissues are associated with promoting cancer cell proliferation Cite
Chang N, Wu C, Chen D, Yeh C, Lin C. High levels of arachidonic acid and peroxisome proliferator-activated receptor-alpha in breast cancer tissues are associated with promoting cancer cell proliferation. The Journal of Nutritional Biochemistry. Elsevier BV; 2013; 24:274-281 10.1016/j.jnutbio.2012.06.005
Breast Feeding, Parity and Breast Cancer Subtypes in a Spanish Cohort Cite
Redondo CM, Gago-Domínguez M, Ponte SM, Castelo ME, Jiang X, García AA, et al. Breast Feeding, Parity and Breast Cancer Subtypes in a Spanish Cohort. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e40543 10.1371/journal.pone.0040543
Apigenin Induces Apoptosis and Blocks Growth of Medroxyprogesterone Acetate-Dependent BT-474 Xenograft Tumors Cite
Mafuvadze B, Liang Y, Besch-Williford C, Zhang X, Hyder SM. Apigenin Induces Apoptosis and Blocks Growth of Medroxyprogesterone Acetate-Dependent BT-474 Xenograft Tumors. Hormones and Cancer. Springer Science and Business Media LLC; 2012; 3:160-171 10.1007/s12672-012-0114-x
Survival and clinicopathological characteristics of breast cancer patient according to different tumour subtypes as determined by hormone receptor and Her2 immunohistochemistry. A single institution survey spanning 1998 to 2010 Cite
García Fernández A, Giménez N, Fraile M, González S, Chabrera C, Torras M, et al. Survival and clinicopathological characteristics of breast cancer patient according to different tumour subtypes as determined by hormone receptor and Her2 immunohistochemistry. A single institution survey spanning 1998 to 2010. The Breast. Elsevier BV; 2012; 21:366-373 10.1016/j.breast.2012.03.004
Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells Cite
Xiao D, Bommareddy A, Kim S, Sehrawat A, Hahm E, Singh SV. Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e32597 10.1371/journal.pone.0032597
Genistein induces enhanced growth promotion in ER-positive/erbB-2-overexpressing breast cancers by ER-erbB-2 cross talk and p27/kip1 downregulation Cite
Yang X, Yang S, McKimmey C, Liu B, Edgerton SM, Bales W, et al. Genistein induces enhanced growth promotion in ER-positive/erbB-2-overexpressing breast cancers by ER-erbB-2 cross talk and p27/kip1 downregulation. Carcinogenesis. Oxford University Press (OUP); 2010; 31:695-702 10.1093/carcin/bgq007
Additive effects of trastuzumab and genistein on human breast cancer cells Cite
Lattrich C, Lubig J, Springwald A, Goerse R, Ortmann O, Treeck O. Additive effects of trastuzumab and genistein on human breast cancer cells. Anti-Cancer Drugs. Ovid Technologies (Wolters Kluwer Health); 2011; 22:253-261 10.1097/cad.0b013e3283427bb5
Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells Cite
Sakla MS, Shenouda NS, Ansell PJ, MacDonald RS, Lubahn DB. Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells. Endocrine. Springer Science and Business Media LLC; 2007; 32:69-78 10.1007/s12020-007-9006-1
Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells Cite
Mai Z, Blackburn GL, Zhou J. Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells. Molecular Carcinogenesis. Wiley; 2007; 46:534-542 10.1002/mc.20300
Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions Cite
Liu B, Fan Z, Edgerton SM, Yang X, Lind SE, Thor AD. Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions. Cell Cycle. Informa UK Limited; 2011; 10:2959-2966 10.4161/cc.10.17.16359
Flaxseed oil–trastuzumab interaction in breast cancer Cite
Mason JK, Chen J, Thompson LU. Flaxseed oil–trastuzumab interaction in breast cancer. Food and Chemical Toxicology. Elsevier BV; 2010; 48:2223-2226 10.1016/j.fct.2010.05.052
Biomarker Expression and Risk of Subsequent Tumors After Initial Ductal Carcinoma In Situ Diagnosis Cite
Kerlikowske K, Molinaro AM, Gauthier ML, Berman HK, Waldman F, Bennington J, et al. Biomarker Expression and Risk of Subsequent Tumors After Initial Ductal Carcinoma In Situ Diagnosis. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2010; 102:627-637 10.1093/jnci/djq101
Use of Four Biomarkers to Evaluate the Risk of Breast Cancer Subtypes in the Women's Contraceptive and Reproductive Experiences Study Cite
Ma H, Wang Y, Sullivan-Halley J, Weiss L, Marchbanks PA, Spirtas R, et al. Use of Four Biomarkers to Evaluate the Risk of Breast Cancer Subtypes in the Women's Contraceptive and Reproductive Experiences Study. Cancer Research. American Association for Cancer Research (AACR); 2010; 70:575-587 10.1158/0008-5472.can-09-3460
Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway Cite
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Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells Cite
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Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells Cite
Menendez J, Ropero S, Lupu R, Colomer R. Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells. Annals of Oncology. Elsevier BV; 2004; 15:1719-1721 10.1093/annonc/mdh442
HER2 (erbB-2)-targeted effects of the ϖ-3 polyunsaturated. Fatty acid α-linolenic acid (ALA; 18:3n-3) in breast cancer cells: the «fat features» of the «Mediterranean diet» as an «anti-HER2 cocktail» Cite
Menéndez JA, Vázquez-Martín A, Ropero S, Colomer R, Lupu R, Trueta J. HER2 (erbB-2)-targeted effects of the ϖ-3 polyunsaturated. Fatty acid α-linolenic acid (ALA; 18:3n-3) in breast cancer cells: the «fat features» of the «Mediterranean diet» as an «anti-HER2 cocktail». Clinical and Translational Oncology. Springer Science and Business Media LLC; 2006; 8:812-820 10.1007/s12094-006-0137-2
Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin™) in breast cancer cells with Her-2/neu oncogene amplification Cite
Menendez J, Vellon L, Colomer R, Lupu R. Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin™) in breast cancer cells with Her-2/neu oncogene amplification. Annals of Oncology. Elsevier BV; 2005; 16:359-371 10.1093/annonc/mdi090
Exogenous supplementation with ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells Cite
Menendez JA, Lupu R, Colomer R. Exogenous supplementation with ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells. European Journal of Cancer Prevention. Ovid Technologies (Wolters Kluwer Health); 2005; 14:263-270 10.1097/00008469-200506000-00011