Tag: HER2HRneg

Articles

• Breast cancer types
• Exercise and breast cancer survival
• Foods to eat and avoid for HER2+ patients and survivors
• HER2+ breast cancer characteristics
• HER2+ recurrence & survival data

News

03/11/18

Flaxseed lignans increase treatment effects of Adriamycin & Taxotere

01/20/13

Some BC types have up to 11% locoregional recurrence after mastectomy

04/12/12

Five-year prognosis by breast cancer subtype

05/09/11

Curcumin and DHA act synergistically in ER-/PR-/HER2+ breast cancer

09/14/10

Does a family history of BC increase the risk of certain subtypes?

Studies

• Antitumor properties of bromelain loaded trastuzumab conjugated niosomes in HER2+ breast cancer cells Cite
  Tut E, Guldu OK, Medine EI. Antitumor properties of bromelain loaded trastuzumab conjugated niosomes in HER2+ breast cancer cells. Journal of Drug Delivery Science and Technology. Elsevier BV; 2024; 101:106243 10.1016/j.jddst.2024.106243
• Continuous exposure to doxorubicin induces stem cell-like characteristics and plasticity in MDA-MB-231 breast cancer cells identified with the SORE6 reporter Cite
  Salinas-Jazmín N, Medina-Mondragón MA, Jiménez-López J, Guerrero-Rodríguez SL, Cuautle-Rodríguez P, Velasco-Velázquez MA. Continuous exposure to doxorubicin induces stem cell-like characteristics and plasticity in MDA-MB-231 breast cancer cells identified with the SORE6 reporter. Cancer Chemotherapy and Pharmacology. Springer Science and Business Media LLC; 2024; 10.1007/s00280-024-04701-4
• Dose/Exposure Relationship of Exercise and Distant Recurrence in Primary Breast Cancer Cite
  Soldato D, Michiels S, Havas J, Di Meglio A, Pagliuca M, Franzoi MA, et al. Dose/Exposure Relationship of Exercise and Distant Recurrence in Primary Breast Cancer. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2024; 10.1200/jco.23.01959
• Abstract PO4-18-03: Combined Treatment with Pyrotinib and Chrysin Synergistically Improve the Autophagy Level in HER2-Positive Breast Cancer by Regulating the miR-16-5p/ZBTB16/G6PD Axis Cite
  Luo T, Zhong X, He P, Zheng D, Cheng Y, Zhu K. Abstract PO4-18-03: Combined Treatment with Pyrotinib and Chrysin Synergistically Improve the Autophagy Level in HER2-Positive Breast Cancer by Regulating the miR-16-5p/ZBTB16/G6PD Axis. Cancer Research. American Association for Cancer Research (AACR); 2024; 84:PO4-18-03-PO4-18-03 10.1158/1538-7445.sabcs23-po4-18-03
• Estrogen Receptor Is Required for Metformin-Induced Apoptosis in Breast Cancer Cells Under Hyperglycemic Conditions Cite
  Sekar AP, Nurmala S, Matsuura E, Tan XW, Rahmasari R, Sauriasari R. Estrogen Receptor Is Required for Metformin-Induced Apoptosis in Breast Cancer Cells Under Hyperglycemic Conditions. Breast Cancer: Basic and Clinical Research. SAGE Publications; 2024; 18 10.1177/11782234241240173
• Chitosan-coated MIL-100(Fe) nanoparticles for enhanced piperine release in breast cancer treatment Cite
  Quijia CR, Ocaña A, Alonso‑Moreno C, Galvão Frem RC, Chorilli M. Chitosan-coated MIL-100(Fe) nanoparticles for enhanced piperine release in breast cancer treatment. Journal of Molecular Structure. Elsevier BV; 2024; 1305:137801 10.1016/j.molstruc.2024.137801
• Green tea extracts and substantial catechin derivatives: Evaluation of their potential against breast cancer Cite
  Özenver N, Ünlü S, Gündoğdu S, Demirezer LÖ. Green tea extracts and substantial catechin derivatives: Evaluation of their potential against breast cancer. Food and Health. Scientific Web Journals (SWJ); 2024; 10:85-95 10.3153/fh24008
• Anthocyanin Oligomers Induce Apoptosis and Autophagy by Inhibiting the mTOR Signaling Pathway in Human Breast Cancer Cells Cite
  Lee M, Hong H, Nam K. Anthocyanin Oligomers Induce Apoptosis and Autophagy by Inhibiting the mTOR Signaling Pathway in Human Breast Cancer Cells. Pharmaceuticals. MDPI AG; 2023; 17:24 10.3390/ph17010024
• Synergistic Anti-Cancer Potential of Phenethyl Isothiocyanate and Curcumin Induces Apoptosis and G2/M Cell Cycle Arrest in HER2-Positive Breast Cancer Cells Cite
  Sirigiripeta S, Dokala A, Anupalli R. Synergistic Anti-Cancer Potential of Phenethyl Isothiocyanate and Curcumin Induces Apoptosis and G2/M Cell Cycle Arrest in HER2-Positive Breast Cancer Cells. Cytology and Genetics. Allerton Press; 2023; 57:611-624 10.3103/s0095452723060087
• Naringenin induces different proliferative effects in estrogen receptor-alpha-66 negative breast cancer cells Cite
  Xu Z, Hu S, Luo N, Liu J, Ren X, Pan X. Naringenin induces different proliferative effects in estrogen receptor-alpha-66 negative breast cancer cells. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-3266516/v1
• Antioxidant Phytocomplexes Extracted from Pomegranate (Punica granatum L.) Using Hydrodynamic Cavitation Show Potential Anticancer Activity In Vitro Cite
  Minutolo A, Gismondi A, Chirico R, Di Marco G, Petrone V, Fanelli M, et al. Antioxidant Phytocomplexes Extracted from Pomegranate (Punica granatum L.) Using Hydrodynamic Cavitation Show Potential Anticancer Activity In Vitro. Antioxidants. MDPI AG; 2023; 12:1560 10.3390/antiox12081560
• The Combined Therapeutic Effect of Capecitabine and Naringin on HER2+ (SK-BR-3) and HER2- (MCF-7) Human Breast Cancer Cells Lines Cite
  Soltannezhad S, Jouni FJ, Osgoei LT. The Combined Therapeutic Effect of Capecitabine and Naringin on HER2+ (SK-BR-3) and HER2- (MCF-7) Human Breast Cancer Cells Lines. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2887641/v1
• Fabrication, optimization, and characterization of pH-responsive PEGylated nanoniosomes containing gingerol for enhanced treatment of breast cancer Cite
  Asghari Lalami Z, Tafvizi F, Naseh V, Salehipour M. Fabrication, optimization, and characterization of pH-responsive PEGylated nanoniosomes containing gingerol for enhanced treatment of breast cancer. Naunyn-Schmiedeberg's Archives of Pharmacology. Springer Science and Business Media LLC; 2023; 10.1007/s00210-023-02579-2
• An investigation into the effects of 6-Gingerol on glucose and glutamine metabolism in breast cancer cell lines Cite
  Ghorbani M, Shafiee SM, Dianati-Nassab A, Behbahani SE, Honardar Z, Khoshdel Z. An investigation into the effects of 6-Gingerol on glucose and glutamine metabolism in breast cancer cell lines. Research Square Platform LLC; 2023; 10.21203/rs.3.rs-2707034/v1
• Combinations of vitamin A and D induced are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways Cite
  Kanabar PN, Los NS, Lawal TO, Patel SM, Raut NA, Maienschein-Cline M, et al. Combinations of vitamin A and D induced are synergistic in breast cancer cells and alter gene expression in the endoplasmic reticulum stress, unfolded protein and estrogen signaling canonical pathways. Functional Foods in Health and Disease. Functional Food Center; 2023; 13:135 10.31989/ffhd.v13i3.1069
• 2,2-Diphenethyl Isothiocyanate Enhances Topoisomerase Inhibitor-Induced Cell Death and Suppresses Multi-Drug Resistance 1 in Breast Cancer Cells Cite
  Aggarwal M. 2,2-Diphenethyl Isothiocyanate Enhances Topoisomerase Inhibitor-Induced Cell Death and Suppresses Multi-Drug Resistance 1 in Breast Cancer Cells. Cancers. MDPI AG; 2023; 15:928 10.3390/cancers15030928
• Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter? Cite
  Khazaei S, Nilsson L, Adrian G, Tryggvadottir H, Konradsson E, Borgquist S, et al. Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter?. Oncotarget. Impact Journals, LLC; 2022; 13:439-453 10.18632/oncotarget.28204
• Myricetin induces apoptosis through the MAPK pathway and regulates JNK‑mediated autophagy in SK‑BR‑3 cells Cite
  Han S, Lee J, Woo J, Jung G, Jung S, Han E, et al. Myricetin induces apoptosis through the MAPK pathway and regulates JNK‑mediated autophagy in SK‑BR‑3 cells. International Journal of Molecular Medicine. Spandidos Publications; 2022; 49 10.3892/ijmm.2022.5110
• Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways Cite
  Wu A, Zhu Y, Han B, Peng J, Deng X, Chen W, et al. Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways. Oncology Letters. Spandidos Publications; 2021; 22 10.3892/ol.2021.13093
• Luteolin-Loading Her-2 Nanospheres Enhances Targeting and Therapeutic Effects of Breast Cancer Cite
  Xiao C, Wang X, Shen J, Xia Y, Qiu S, Liang X, et al. Luteolin-Loading Her-2 Nanospheres Enhances Targeting and Therapeutic Effects of Breast Cancer. Journal of Biomedical Nanotechnology. American Scientific Publishers; 2021; 17:1545-1553 10.1166/jbn.2021.3137
• Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1 Cite
  Woo J, Kim JB, Cho T, Yoo EH, Moon B, Kwon H, et al. Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1. PLOS ONE. Public Library of Science (PLoS); 2021; 16:e0257298 10.1371/journal.pone.0257298
• Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer Cite
  Farghadani R, Naidu R. Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer. Cancers. MDPI AG; 2021; 13:3427 10.3390/cancers13143427
• Time to Completion of Breast Cancer Treatment and Survival Cite
  Pratt D, Burneikis T, Tu C, Grobmyer S. Time to Completion of Breast Cancer Treatment and Survival. Annals of Surgical Oncology. Springer Science and Business Media LLC; 2021; 10.1245/s10434-021-10116-9
• Tamoxifen overcomes the trastuzumab-resistance of SK-BR-3 tumorspheres by targeting crosstalk between cytoplasmic estrogen receptor α and the EGFR/HER2 signaling pathway Cite
  Kwon Y, Nam K, Kim S. Tamoxifen overcomes the trastuzumab-resistance of SK-BR-3 tumorspheres by targeting crosstalk between cytoplasmic estrogen receptor α and the EGFR/HER2 signaling pathway. Biochemical Pharmacology. Elsevier BV; 2021;:114635 10.1016/j.bcp.2021.114635
• Mechanism Underlying Resveratrol's Attenuation of Paclitaxel Cytotoxicity in Human Breast Cancer Cells: Role of the SIRT1-FOXO1-HER3 Signaling Pathway Cite
  Fukui M, Choi HJ, Wang P, Zhu BT. Mechanism Underlying Resveratrol's Attenuation of Paclitaxel Cytotoxicity in Human Breast Cancer Cells: Role of the SIRT1-FOXO1-HER3 Signaling Pathway. Cancer Treatment and Research Communications. Elsevier BV; 2021;:100386 10.1016/j.ctarc.2021.100386
• Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models Cite
  Filip-Psurska B, Psurski M, Anisiewicz A, Libako P, Zbrojewicz E, Maciejewska M, et al. Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models. International Journal of Molecular Sciences. MDPI AG; 2021; 22:2781 10.3390/ijms22052781
• Metformin partially reverses the inhibitory effect of co-culture with ER-/PR-/HER2+ breast cancer cells on biomarkers of monocyte antitumor activity Cite
  Dahmani Z, Addou-Klouche L, Gizard F, Dahou S, Messaoud A, Chahinez Djebri N, et al. Metformin partially reverses the inhibitory effect of co-culture with ER-/PR-/HER2+ breast cancer cells on biomarkers of monocyte antitumor activity. PLOS ONE. Public Library of Science (PLoS); 2020; 15:e0240982 10.1371/journal.pone.0240982
• A nanotechnology-based new approach in the treatment of breast cancer: Biosynthesized silver nanoparticles using Cuminum cyminum L. seed extract Cite
  Dinparvar S, Bagirova M, Allahverdiyev AM, Abamor ES, Safarov T, Aydogdu M, et al. A nanotechnology-based new approach in the treatment of breast cancer: Biosynthesized silver nanoparticles using Cuminum cyminum L. seed extract. Journal of Photochemistry and Photobiology B: Biology. Elsevier BV; 2020; 208:111902 10.1016/j.jphotobiol.2020.111902
• Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLCγ-1 Downregulation Cite
  Layosa MAA, Lage NN, Chew BP, Atienza L, Mertens-Talcott S, Talcott S, et al. Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLCγ-1 Downregulation. Nutrition and Cancer. Informa UK Limited; 2020;:1-13 10.1080/01635581.2020.1817514
• Lavandula Angustifolia Essential Oil Loaded in Liposomal Nano-Carriers Regulate the HER2 and CASP3 Genes in MCF-7 and SK-BR-3 Cell-Lines Cite
  Mohammadpanah M, Mojodi E, Haghiralsadat F, Sabbagh SK, Rajabi M. Lavandula Angustifolia Essential Oil Loaded in Liposomal Nano-Carriers Regulate the HER2 and CASP3 Genes in MCF-7 and SK-BR-3 Cell-Lines. Research Square; 2020; 10.21203/rs.3.rs-40618/v1
• Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage Cite
  Bakar-Ates F, Ozkan E, Sengel-Turk CT. Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage. International Journal of Pharmaceutics. Elsevier BV; 2020; 586:119565 10.1016/j.ijpharm.2020.119565
• A Polyphenol-Rich Muscadine Grape Extract Inhibits HER + Breast Cancer and Protects Against Trastuzumab-Induced Cardiotoxicity Cite
  Mackert J, Gallagher P, Tallant E. A Polyphenol-Rich Muscadine Grape Extract Inhibits HER + Breast Cancer and Protects Against Trastuzumab-Induced Cardiotoxicity. Current Developments in Nutrition. Oxford University Press (OUP); 2020; 4:334-334 10.1093/cdn/nzaa044_033
• Antitumor potential of dark sweet cherry sweet (Prunus avium) phenolics in suppressing xenograft tumor growth of MDA-MB-453 breast cancer cells Cite
  Noratto G, Layosa MA, Lage NN, Atienza L, Ivanov I, Mertens-Talcott SU, et al. Antitumor potential of dark sweet cherry sweet (Prunus avium) phenolics in suppressing xenograft tumor growth of MDA-MB-453 breast cancer cells. The Journal of Nutritional Biochemistry. Elsevier BV; 2020; 84:108437 10.1016/j.jnutbio.2020.108437
• Lower concentrations of curcumin inhibit Her2-Akt pathway components in human breast cancer cells, and other dietary botanicals potentiate this and lapatinib inhibition Cite
  Saxena AR, Ilic Z, Sripada V, Crawford DR. Lower concentrations of curcumin inhibit Her2-Akt pathway components in human breast cancer cells, and other dietary botanicals potentiate this and lapatinib inhibition. Nutrition Research. Elsevier BV; 2020; 78:93-104 10.1016/j.nutres.2020.05.007
• Astaxanthin Modulates Apoptotic Molecules to Induce Death of SKBR3 Breast Cancer Cells Cite
  Kim MS, Ahn YT, Lee CW, Kim H, An WG. Astaxanthin Modulates Apoptotic Molecules to Induce Death of SKBR3 Breast Cancer Cells. Marine Drugs. MDPI AG; 2020; 18:266 10.3390/md18050266
• Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session Cite
  Deken MM, Kijanka MM, Beltrán Hernández I, Slooter MD, de Bruijn HS, van Diest PJ, et al. Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session. Journal of Controlled Release. Elsevier BV; 2020; 323:269-281 10.1016/j.jconrel.2020.04.030
• Abstract P3-11-17: Statins suppress the aggressive phenotype of triple negative breast cancer cells via modulation of EGFR signalling Cite
  Smith C, Alim S, Kadi A, Lawati RA, Miles M, Hiscox S. Abstract P3-11-17: Statins suppress the aggressive phenotype of triple negative breast cancer cells via modulation of EGFR signalling. Poster Session Abstracts. American Association for Cancer Research; 2020; 10.1158/1538-7445.sabcs19-p3-11-17
• Abstract P3-05-11: Cannabidiol increases potency of tamoxifen in inhibiting breast cancer cell viability Cite
  Dobovišek L, Novak M, Krstanović F, Ferk P, Borštnar S, Turnšek TL, et al. Abstract P3-05-11: Cannabidiol increases potency of tamoxifen in inhibiting breast cancer cell viability. Poster Session Abstracts. American Association for Cancer Research; 2020; 10.1158/1538-7445.sabcs19-p3-05-11
• Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects Cite
  Tang S, Deng X, Zhou J, Li Q, Ge X, Miao L. Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects. Biomedicine & Pharmacotherapy. Elsevier BV; 2019; 121:109604 10.1016/j.biopha.2019.109604
• Relationship between Diabetes and Diabetes Medications and Risk of Different Molecular Subtypes of Breast Cancer Cite
  Chen H, Cook LS, Tang MC, Hill DA, Wiggins CL, Li CI. Relationship between Diabetes and Diabetes Medications and Risk of Different Molecular Subtypes of Breast Cancer. Cancer Epidemiology Biomarkers & Prevention. American Association for Cancer Research (AACR); 2019; 28:1802-1808 10.1158/1055-9965.epi-19-0291
• Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment Cite
  Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, et al. Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. Cellular Oncology. Springer Science and Business Media LLC; 2019; 42:815-828 10.1007/s13402-019-00464-w
• Abstract 1860: Muscadine grape extract prevents proliferation of trastuzumab-sensitive and -resistant HER2 positive breast cancer cells and has synergistic effects when combined with trastuzumab Cite
  Mackert J, Gallagher PE, Tallant EA. Abstract 1860: Muscadine grape extract prevents proliferation of trastuzumab-sensitive and -resistant HER2 positive breast cancer cells and has synergistic effects when combined with trastuzumab. Cancer Chemistry. American Association for Cancer Research; 2019; 10.1158/1538-7445.am2019-1860
• Dark Sweet Cherry (Prunus Avium L.) Phenolics Induce Apoptosis and Inhibit Invasion on Breast Cancer MDA-MB-453 Through MAPK-dependent and Independent Pathways (P05-007-19) Cite
  Layosa MA, Lage N, Talcott S, Talcott S, Atienza L, Chew B, et al. Dark Sweet Cherry (Prunus Avium L.) Phenolics Induce Apoptosis and Inhibit Invasion on Breast Cancer MDA-MB-453 Through MAPK-dependent and Independent Pathways (P05-007-19). Current Developments in Nutrition. Oxford University Press (OUP); 2019; 3 10.1093/cdn/nzz030.p05-007-19
• Thymoquinone Augments Cyclophosphamide-Mediated Inhibition of Cell Proliferation in Breast Cancer Cells Cite
  Khan A, Aldebasy YH, Alsuhaibani SA, Khan MA. Thymoquinone Augments Cyclophosphamide-Mediated Inhibition of Cell Proliferation in Breast Cancer Cells. Asian Pacific Journal of Cancer Prevention. EpiSmart Science Vector Ltd; 2019; 20:1153-1160 10.31557/apjcp.2019.20.4.1153
• (−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo Cite
  Siddique A, Ebrahim H, Akl M, Ayoub N, Goda A, Mohyeldin M, et al. (−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo. Nutrients. MDPI AG; 2019; 11:412 10.3390/nu11020412
• Anti-metastatic and anti-proliferative activity of eugenol against triple negative and HER2 positive breast cancer cells Cite
  Abdullah ML, Hafez MM, Al-Hoshani A, Al-Shabanah O. Anti-metastatic and anti-proliferative activity of eugenol against triple negative and HER2 positive breast cancer cells. BMC Complementary and Alternative Medicine. Springer Science and Business Media LLC; 2018; 18 10.1186/s12906-018-2392-5
• Cytotoxic and antioxidant properties in vitro of functional beverages based on blackberry (Rubus glaucus Benth) and soursop (Annona muricata L) pulps Cite
  Zambrano A, Raybaudi-Massilia R, Arvelo F, Sojo F. Cytotoxic and antioxidant properties in vitro of functional beverages based on blackberry (Rubus glaucus Benth) and soursop (Annona muricata L) pulps. Functional Foods in Health and Disease. Functional Food Center; 2018; 8:531 10.31989/ffhd.v8i11.541
• Fisetin induces apoptosis in breast cancer MDA‐MB‐453 cells through degradation of HER2/neu and via the PI3K/Akt pathway Cite
  Guo G, Zhang W, Dang M, Yan M, Chen Z. Fisetin induces apoptosis in breast cancer MDA‐MB‐453 cells through degradation of HER2/neu and via the PI3K/Akt pathway. Journal of Biochemical and Molecular Toxicology. Wiley; 2018; 33:e22268 10.1002/jbt.22268
• Evaluation of the safety profiles of estrogenic Chinese herbal medicines in breast cancer Cite
  Yue GG, Wong L, Leung H, Gao S, Tsang JY, Lin Z, et al. Evaluation of the safety profiles of estrogenic Chinese herbal medicines in breast cancer. Phytomedicine. Elsevier BV; 2019; 56:103-117 10.1016/j.phymed.2018.10.003
• Abstract 2683: The olive-based oleocanthal as a dual HER2-MET inhibitor for the control of breast cancer recurrence Cite
  Siddique AB, Ebrahim H, Mohyeldin M, Jois SD, Sayed KAE. Abstract 2683: The olive-based oleocanthal as a dual HER2-MET inhibitor for the control of breast cancer recurrence. Cancer Chemistry. American Association for Cancer Research; 2018; 10.1158/1538-7445.am2018-2683
• Anti-oxidation properties of leaves, skin, pulp, and seeds extracts from green papaya and their anti-cancer activities in breast cancer cells Cite
  Hadadi SA, Li H, Rafie R, Kaseloo P, Witiak SM, Siddiqui RA. Anti-oxidation properties of leaves, skin, pulp, and seeds extracts from green papaya and their anti-cancer activities in breast cancer cells. Journal of Cancer Metastasis and Treatment. OAE Publishing Inc.; 2018; 4:25 10.20517/2394-4722.2018.22
• Bisphenol AF as an activator of human estrogen receptor β1 (ERβ1) in breast cancer cell lines Cite
  Okazaki H, Hirao-Suzuki M, Takeda S, Takemoto Y, Mizunoe R, Haraguchi K, et al. Bisphenol AF as an activator of human estrogen receptor β1 (ERβ1) in breast cancer cell lines. The Journal of Toxicological Sciences. Japanese Society of Toxicology; 2018; 43:321-327 10.2131/jts.43.321
• Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3 Cite
  Di Y, De Silva F, Krol ES, Alcorn J. Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3. Nutrition and Cancer. Informa UK Limited; 2018; 70:306-315 10.1080/01635581.2018.1421677
• Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes Cite
  Amaral MEA, Nery LR, Leite CE, de Azevedo Junior WF, Campos MM. Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes. Investigational New Drugs. Springer Science and Business Media LLC; 2018; 36:782-796 10.1007/s10637-018-0568-y
• Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling Cite
  Ku JM, Hong SH, Kim HI, Lim YS, Lee SJ, Kim M, et al. Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling. European Journal of Inflammation. SAGE Publications; 2018; 16:1721727X1775180 10.1177/1721727x17751809
• Equol Enhances Apoptosis-inducing Activity of Genistein by Increasing Bax/Bcl-xL Expression Ratio in MCF-7 Human Breast Cancer Cells Cite
  Ono M, Ejima K, Higuchi T, Takeshima M, Wakimoto R, Nakano S. Equol Enhances Apoptosis-inducing Activity of Genistein by Increasing Bax/Bcl-xL Expression Ratio in MCF-7 Human Breast Cancer Cells. Nutrition and Cancer. Informa UK Limited; 2017; 69:1300-1307 10.1080/01635581.2017.1367945
• Cooperative antitumor activities of carnosic acid and Trastuzumab in ERBB2+ breast cancer cells Cite
  D’Alesio C, Bellese G, Gagliani MC, Aiello C, Grasselli E, Marcocci G, et al. Cooperative antitumor activities of carnosic acid and Trastuzumab in ERBB2+ breast cancer cells. Journal of Experimental & Clinical Cancer Research. Springer Science and Business Media LLC; 2017; 36 10.1186/s13046-017-0615-0
• Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line Cite
  Shahinfar P, Motamed N, Birjandian E, Shabanpour O. Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line. Indian Journal of Pharmaceutical Education and Research. EManuscript Services; 2017; 51:597-602 10.5530/ijper.51.4.89
• Bisphenol A induces proliferative effects on both breast cancer cells and vascular endothelial cells through a shared GPER-dependent pathway in hypoxia Cite
  Xu F, Wang X, Wu N, He S, Yi W, Xiang S, et al. Bisphenol A induces proliferative effects on both breast cancer cells and vascular endothelial cells through a shared GPER-dependent pathway in hypoxia. Environmental Pollution. Elsevier BV; 2017; 231:1609-1620 10.1016/j.envpol.2017.09.069
• Vitamin D enhances omega-3 polyunsaturated fatty acids-induced apoptosis in breast cancer cells Cite
  Yang J, Zhu S, Lin G, Song C, He Z. Vitamin D enhances omega-3 polyunsaturated fatty acids-induced apoptosis in breast cancer cells. Cell Biology International. Wiley; 2017; 41:890-897 10.1002/cbin.10806
• ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines Cite
  Lin G, Zhu S, Wu Y, Song C, Wang W, Zhang Y, et al. ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines. Scientific Reports. Springer Science and Business Media LLC; 2017; 7 10.1038/s41598-017-03231-9
• Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells Cite
  Pawlik A, Wała M, Hać A, Felczykowska A, Herman-Antosiewicz A. Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells. Phytomedicine. Elsevier BV; 2017; 29:1-10 10.1016/j.phymed.2017.03.007
• Piperlongumine downregulates the expression of HER family in breast cancer cells Cite
  Jin H, Park J, Kim H, Chang YH, Hong YJ, Park I, et al. Piperlongumine downregulates the expression of HER family in breast cancer cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2017; 486:1083-1089 10.1016/j.bbrc.2017.03.166
• [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells Cite
  Bernard MM, McConnery JR, Hoskin DW. [10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cells. Experimental and Molecular Pathology. Elsevier BV; 2017; 102:370-376 10.1016/j.yexmp.2017.03.006
• Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation Cite
  Lewinska A, Bednarz D, Adamczyk-Grochala J, Wnuk M. Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation. Redox Biology. Elsevier BV; 2017; 12:469-482 10.1016/j.redox.2017.03.014
• Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells Cite
  Tseng H, Wang Y, Tzeng Y, Chen D, Liao Y, Chiu H, et al. Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells. The American Journal of Chinese Medicine. World Scientific Pub Co Pte Lt; 2017; 45:337-350 10.1142/s0192415x17500215
• Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells Cite
  Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Deregowska A, Wnuk M. Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells. Apoptosis. Springer Science and Business Media LLC; 2017; 22:800-815 10.1007/s10495-017-1353-7
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• Induction of G2M Arrest by Flavokawain A, A Kava Chalcone, Increases the Responsiveness of HER2 Overexpressing Breast Cancer Cells to Herceptin Cite
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• Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells Cite
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• Mechanisms by Which Low Glucose Enhances the Cytotoxicity of Metformin to Cancer Cells Both In Vitro and In Vivo Cite
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• Wasabi-Derived 6-(Methylsulfinyl)Hexyl Isothiocyanate Induces Apoptosis in Human Breast Cancer by Possible Involvement of the NF-κB Pathways Cite
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• 3, 3′-diindolylmethane Enhances the Effectiveness of Herceptin against HER-2/Neu-Expressing Breast Cancer Cells Cite
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• Direct regulation of caspase-3 by the transcription factor AP-2α is involved in aspirin-induced apoptosis in MDA-MB-453 breast cancer cells Cite
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• Chronic Morphine Treatment Attenuates Cell Growth of Human BT474 Breast Cancer Cells by Rearrangement of the ErbB Signalling Network Cite
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• Inhibition of constitutive Akt (PKB) phosphorylation by docosahexaenoic acid in the human breast cancer cell line MDA-MB-453 Cite
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• Docosahexanoic Acid Improves Chemotherapy Efficacy by Inducing CD95 Translocation to Lipid Rafts in ER− Breast Cancer Cells Cite
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• Arachidonic acid promotes FAK activation and migration in MDA-MB-231 breast cancer cells Cite
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• The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression Cite
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• Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway Cite
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• Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions Cite
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• Prognosis in women with small (T1mic,T1a,T1b) node-negative operable breast cancer by immunohistochemically selected subtypes Cite
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• A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone Cite
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• Family history of breast cancer in first-degree relatives and triple-negative breast cancer risk Cite
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• The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells Cite
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• Use of Four Biomarkers to Evaluate the Risk of Breast Cancer Subtypes in the Women's Contraceptive and Reproductive Experiences Study Cite
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• Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway Cite
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• 3,3′-Diindolylmethane and Paclitaxel Act Synergistically to Promote Apoptosis in HER2/Neu Human Breast Cancer Cells Cite
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• Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells Cite
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• HER2 (erbB-2)-targeted effects of the ϖ-3 polyunsaturated. Fatty acid α-linolenic acid (ALA; 18:3n-3) in breast cancer cells: the «fat features» of the «Mediterranean diet» as an «anti-HER2 cocktail» Cite
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• Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells Cite
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• Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin™) in breast cancer cells with Her-2/neu oncogene amplification Cite
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• Prepubertal Gynecomastia Linked to Lavender and Tea Tree Oils Cite
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