Tag: ARpos

Androgen receptor positive: Cells that have a nuclear receptor protein that binds androgenic hormones such as testosterone and dihydrotestosterone. In other words, AR+ cells have an interior receptor that is activated by androgens.

Studies

  • ARe we there yet? Understanding androgen receptor signaling in breast cancer Cite
    Michmerhuizen AR, Spratt DE, Pierce LJ, Speers CW. ARe we there yet? Understanding androgen receptor signaling in breast cancer. npj Breast Cancer. Springer Science and Business Media LLC; 2020; 6 10.1038/s41523-020-00190-9
  • Role of androgen receptor expression in early stage ER+/PgR−/HER2– breast cancer Cite
    Tagliaferri B, Quaquarini E, Palumbo R, Balletti E, Presti D, Malovini A, et al. Role of androgen receptor expression in early stage ER+/PgR−/HER2– breast cancer. Therapeutic Advances in Medical Oncology. SAGE Publications; 2020; 12:175883592095835 10.1177/1758835920958355
  • Triple-negative pleomorphic lobular carcinoma and expression of androgen receptor: Personal case series and review of the literature Cite
    Taniguchi K, Takada S, Omori M, Igawa T, Nishimura MF, Morito T, et al. Triple-negative pleomorphic lobular carcinoma and expression of androgen receptor: Personal case series and review of the literature. PLOS ONE. Public Library of Science (PLoS); 2020; 15:e0235790 10.1371/journal.pone.0235790
  • Abstract B105: The impact of ancestry on mutational and immune signatures in triple-negative breast cancers Cite
    Hughley RW, Yates C, Polak P. Abstract B105: The impact of ancestry on mutational and immune signatures in triple-negative breast cancers. Poster Presentations - Proffered Abstracts. American Association for Cancer Research; 2020; 10.1158/1538-7755.disp19-b105
  • Biological and clinical features of early triple-negative invasive lobular carcinomas of the breast. Cite
    Conforti F, Pala L, Guerini Rocco E, Pagan E, Bagnardi V, Montagna E, et al. Biological and clinical features of early triple-negative invasive lobular carcinomas of the breast.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2020; 38:e12570-e12570 10.1200/jco.2020.38.15_suppl.e12570
  • Gene expression profiles for low-dose exposure to diethyl phthalate in rodents and humans: a translational study with implications for breast carcinogenesis Cite
    Gopalakrishnan K, Aushev VN, Manservisi F, Falcioni L, Panzacchi S, Belpoggi F, et al. Gene expression profiles for low-dose exposure to diethyl phthalate in rodents and humans: a translational study with implications for breast carcinogenesis. Scientific Reports. Springer Science and Business Media LLC; 2020; 10 10.1038/s41598-020-63904-w
  • Breast Cancer in Men: Oncology Cite
    Incorvaia L, Castiglia M, Ottini L, Gori S, Russo A, Bazan V. Breast Cancer in Men: Oncology. Plastic and Cosmetic Surgery of the Male Breast. Springer International Publishing; 2020;:85-92 10.1007/978-3-030-25502-2_10
  • Quadruple negative breast cancer Cite
    Huang M, Wu J, Ling R, Li N. Quadruple negative breast cancer. Breast Cancer. Springer Science and Business Media LLC; 2020; 27:527-533 10.1007/s12282-020-01047-6
  • Dark Sweet Cherry (Prunus Avium L.) Phenolics Induce Apoptosis and Inhibit Invasion on Breast Cancer MDA-MB-453 Through MAPK-dependent and Independent Pathways (P05-007-19) Cite
    Layosa MA, Lage N, Talcott S, Talcott S, Atienza L, Chew B, et al. Dark Sweet Cherry (Prunus Avium L.) Phenolics Induce Apoptosis and Inhibit Invasion on Breast Cancer MDA-MB-453 Through MAPK-dependent and Independent Pathways (P05-007-19). Current Developments in Nutrition. Oxford University Press (OUP); 2019; 3 10.1093/cdn/nzz030.p05-007-19
  • Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy Cite
    Jongen L, Floris G, Wildiers H, Claessens F, Richard F, Laenen A, et al. Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2019; 176:699-708 10.1007/s10549-019-05252-6
  • Invasive breast cancers in adolescent and young adult women show more aggressive immunohistochemical and clinical features than those in women aged 40–44 years Cite
    Hironaka-Mitsuhashi A, Tsuda H, Yoshida M, Shimizu C, Asaga S, Hojo T, et al. Invasive breast cancers in adolescent and young adult women show more aggressive immunohistochemical and clinical features than those in women aged 40–44 years. Breast Cancer. Springer Science and Business Media LLC; 2018; 26:386-396 10.1007/s12282-018-00937-0
  • Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses’ Health Studies Cite
    Kensler KH, Poole EM, Heng YJ, Collins LC, Glass B, Beck AH, et al. Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses’ Health Studies. JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2018; 111:700-708 10.1093/jnci/djy173
  • Fisetin induces apoptosis in breast cancer MDA‐MB‐453 cells through degradation of HER2/neu and via the PI3K/Akt pathway Cite
    Guo G, Zhang W, Dang M, Yan M, Chen Z. Fisetin induces apoptosis in breast cancer MDA‐MB‐453 cells through degradation of HER2/neu and via the PI3K/Akt pathway. Journal of Biochemical and Molecular Toxicology. Wiley; 2018; 33:e22268 10.1002/jbt.22268
  • Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy? Cite
    Bronte G, Rocca A, Ravaioli S, Puccetti M, Tumedei MM, Scarpi E, et al. Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?. BMC Cancer. Springer Science and Business Media LLC; 2018; 18 10.1186/s12885-018-4239-3
  • The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome Cite
    Ricciardelli C, Bianco-Miotto T, Jindal S, Butler LM, Leung S, McNeil CM, et al. The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome. Clinical Cancer Research. American Association for Cancer Research (AACR); 2018; 24:2328-2341 10.1158/1078-0432.ccr-17-1199
  • HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors Cite
    Daemen A, Manning G. HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors. Breast Cancer Research. Springer Science and Business Media LLC; 2018; 20 10.1186/s13058-018-0933-y
  • Characterization of male breast cancer: results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program Cite
    Cardoso F, Bartlett J, Slaets L, van Deurzen C, van Leeuwen-Stok E, Porter P, et al. Characterization of male breast cancer: results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program. Annals of Oncology. Elsevier BV; 2018; 29:405-417 10.1093/annonc/mdx651
  • The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer Cite
    Wellberg EA, Checkley LA, Giles ED, Johnson SJ, Oljira R, Wahdan-Alaswad R, et al. The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer. Hormones and Cancer. Springer Science and Business Media LLC; 2017; 8:269-285 10.1007/s12672-017-0302-9
  • Abstract 4826: Maternal high butter fat intake heightens mammary cancer risk in offsprings gestationally exposed to bisphenol A at environmentally relevant dose Cite
    Leung Y, Govindarajah V, Cheong A, Song D, Zhu X, Ying J, et al. Abstract 4826: Maternal high butter fat intake heightens mammary cancer risk in offsprings gestationally exposed to bisphenol A at environmentally relevant dose. Tumor Biology. American Association for Cancer Research; 2017; 10.1158/1538-7445.am2017-4826
  • Beyond triple-negative breast cancer and African ancestry: Tumor phenotypes among internationally diverse patient populations. Cite
    Jiagge EM, Jibril A, Divine G, Gyan KK, Bensenhaver JM, Oppong JK, et al. Beyond triple-negative breast cancer and African ancestry: Tumor phenotypes among internationally diverse patient populations.. Journal of Clinical Oncology. American Society of Clinical Oncology (ASCO); 2017; 35:1101-1101 10.1200/jco.2017.35.15_suppl.1101
  • Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer Cite
    Barton VN, Christenson JL, Gordon MA, Greene LI, Rogers TJ, Butterfield K, et al. Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer. Cancer Research. American Association for Cancer Research (AACR); 2017; 77:3455-3466 10.1158/0008-5472.can-16-3240
  • A comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women Cite
    Tseng L, Chiu J, Liu C, Tsai Y, Wang Y, Yang C, et al. A comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2017; 163:241-254 10.1007/s10549-017-4195-7
  • Male Breast Cancer Cite
    Serdy KM, Leone JP, Dabbs DJ, Bhargava R. Male Breast Cancer. American Journal of Clinical Pathology. Oxford University Press (OUP); 2017;:aqw207 10.1093/ajcp/aqw207
  • Abstract B20: Targeting androgen receptor and vitamin D receptor in triple negative breast cancers Cite
    Thakkar A, Wang B, Picon-Ruiz M, Ince T. Abstract B20: Targeting androgen receptor and vitamin D receptor in triple negative breast cancers. Targeting Epigenetics. American Association for Cancer Research; 2017; 10.1158/1557-3265.pmccavuln16-b20
  • Special considerations in the evaluation and management of breast cancer in men11This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Cite
    Massarweh SA, Choi GL. Special considerations in the evaluation and management of breast cancer in men11This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.. Current Problems in Cancer. Elsevier BV; 2016; 40:163-171 10.1016/j.currproblcancer.2016.09.003
  • Early versus late distant metastasis and adjuvant chemotherapy alone versus both radiotherapy and chemotherapy in molecular apocrine breast cancer Cite
    Liu X, Yang Y, Feng X, Shen H, Liu J, Liu X, et al. Early versus late distant metastasis and adjuvant chemotherapy alone versus both radiotherapy and chemotherapy in molecular apocrine breast cancer. Oncotarget. Impact Journals, LLC; 2016; 7:48905-48917 10.18632/oncotarget.10211
  • Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer Cite
    Zhu A, Li Y, Song W, Xu Y, Yang F, Zhang W, et al. Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer. Cellular Physiology and Biochemistry. S. Karger AG; 2016; 38:1003-1014 10.1159/000443052
  • Endocrine disrupting chemicals (EDCs) and female cancer: Informing the patients Cite
    Rachoń D. Endocrine disrupting chemicals (EDCs) and female cancer: Informing the patients. Reviews in Endocrine and Metabolic Disorders. Springer Science and Business Media LLC; 2015; 16:359-364 10.1007/s11154-016-9332-9
  • Differential Effects of Organic and Inorganic Mercury on Phenotypically Variant Breast Cancer Cell Lines Cite
    R Wallace D. Differential Effects of Organic and Inorganic Mercury on Phenotypically Variant Breast Cancer Cell Lines. Journal of Clinical Toxicology. OMICS Publishing Group; 2016; 05 10.4172/2161-0495.1000273
  • Clinical verification of sensitivity to preoperative chemotherapy in cases of androgen receptor-expressing positive breast cancer Cite
    Asano Y, Kashiwagi S, Onoda N, Kurata K, Morisaki T, Noda S, et al. Clinical verification of sensitivity to preoperative chemotherapy in cases of androgen receptor-expressing positive breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2016; 114:14-20 10.1038/bjc.2015.434
  • Androgen receptor expression predicts beneficial tamoxifen response in oestrogen receptor-α-negative breast cancer Cite
    Hilborn E, Gacic J, Fornander T, Nordenskjöld B, Stål O, Jansson A. Androgen receptor expression predicts beneficial tamoxifen response in oestrogen receptor-α-negative breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2016; 114:248-255 10.1038/bjc.2015.464
  • Androgen receptor and antiandrogen therapy in male breast cancer Cite
    Di Lauro L, Barba M, Pizzuti L, Vici P, Sergi D, Di Benedetto A, et al. Androgen receptor and antiandrogen therapy in male breast cancer. Cancer Letters. Elsevier BV; 2015; 368:20-25 10.1016/j.canlet.2015.07.040
  • Role of Androgen and Estrogen Receptors as Prognostic and Potential Predictive Markers of Ductal Carcinoma in Situ of the Breast Cite
    Tumedei MM, Silvestrini R, Ravaioli S, Massa I, Maltoni R, Rocca A, et al. Role of Androgen and Estrogen Receptors as Prognostic and Potential Predictive Markers of Ductal Carcinoma in Situ of the Breast. The International Journal of Biological Markers. SAGE Publications; 2015; 30:425-428 10.5301/jbm.5000163
  • Androgen Receptor (AR), E-Cadherin, and Ki-67 as Emerging Targets and Novel Prognostic Markers in Triple-Negative Breast Cancer (TNBC) Patients Cite
    Ricciardi GRR, Adamo B, Ieni A, Licata L, Cardia R, Ferraro G, et al. Androgen Receptor (AR), E-Cadherin, and Ki-67 as Emerging Targets and Novel Prognostic Markers in Triple-Negative Breast Cancer (TNBC) Patients. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0128368 10.1371/journal.pone.0128368
  • The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity Cite
    Linnewiel-Hermoni K, Khanin M, Danilenko M, Zango G, Amosi Y, Levy J, et al. The anti-cancer effects of carotenoids and other phytonutrients resides in their combined activity. Archives of Biochemistry and Biophysics. Elsevier BV; 2015; 572:28-35 10.1016/j.abb.2015.02.018
  • Expression of androgen receptor in inflammatory breast cancer and its clinical relevance Cite
    Gong Y, Wei W, Wu Y, Ueno NT, Huo L. Expression of androgen receptor in inflammatory breast cancer and its clinical relevance. Cancer. Wiley; 2014; 120:1775-1779 10.1002/cncr.28667
  • Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort Cite
    Elebro K, Butt S, Dorkhan M, Jernström H, Borgquist S. Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort. Cancer Causes & Control. Springer Science and Business Media LLC; 2014; 25:945-957 10.1007/s10552-014-0394-2
  • Androgen Receptor Expression and Outcomes in Early Breast Cancer: A Systematic Review and Meta-Analysis Cite
    Vera-Badillo FE, Templeton AJ, de Gouveia P, Diaz-Padilla I, Bedard PL, Al-Mubarak M, et al. Androgen Receptor Expression and Outcomes in Early Breast Cancer: A Systematic Review and Meta-Analysis. JNCI Journal of the National Cancer Institute. Oxford University Press (OUP); 2013; 106:djt319-djt319 10.1093/jnci/djt319
  • Bisphenol A: A Model Endocrine Disrupting Chemical With a New Potential Mechanism of Action Cite
    Nagel SC, Bromfield JJ. Bisphenol A: A Model Endocrine Disrupting Chemical With a New Potential Mechanism of Action. Endocrinology. The Endocrine Society; 2013; 154:1962-1964 10.1210/en.2013-1370
  • Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor Cite
    Watanabe Y, Kojima H, Takeuchi S, Uramaru N, Ohta S, Kitamura S. Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor. Food and Chemical Toxicology. Elsevier BV; 2013; 57:227-234 10.1016/j.fct.2013.03.036
  • Triple-negative Breast Carcinoma in African American and Caucasian Women Cite
    Sullivan HC, Oprea-Ilies G, Adams AL, Page AJ, Kim S, Wang J, et al. Triple-negative Breast Carcinoma in African American and Caucasian Women. Applied Immunohistochemistry & Molecular Morphology. Ovid Technologies (Wolters Kluwer Health); 2014; 22:17-23 10.1097/pai.0b013e318281148e
  • Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor Cite
    Medjakovic S, Zoechling A, Gerster P, Ivanova MM, Teng Y, Klinge CM, et al. Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. Environmental Toxicology. Wiley; 2013; 29:1201-1216 10.1002/tox.21852
  • Endocrine Disruptors Fludioxonil and Fenhexamid Stimulate miR-21 Expression in Breast Cancer Cells Cite
    Teng Y, Manavalan TT, Hu C, Medjakovic S, Jungbauer A, Klinge CM. Endocrine Disruptors Fludioxonil and Fenhexamid Stimulate miR-21 Expression in Breast Cancer Cells. Toxicological Sciences. Oxford University Press (OUP); 2012; 131:71-83 10.1093/toxsci/kfs290
  • Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: Relevant exposure measures for endocrine disruptors in epidemiologic studies? Cite
    Brouwers MM, Besselink H, Bretveld RW, Anzion R, Scheepers PT, Brouwer A, et al. Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: Relevant exposure measures for endocrine disruptors in epidemiologic studies?. Environment International. Elsevier BV; 2011; 37:557-564 10.1016/j.envint.2010.11.001
  • Oestrogenic and androgenic activity of triclosan in breast cancer cells Cite
    Gee RH, Charles A, Taylor N, Darbre PD. Oestrogenic and androgenic activity of triclosan in breast cancer cells. Journal of Applied Toxicology. Wiley; 2007; 28:78-91 10.1002/jat.1316