Tag: breastCancerStemCell

News

09/10/19

Watercress compound PEITC inhibits progression of HER2+ BC

04/21/18

Quercetin can reverse chemotherapy resistance in ER+/PR+ BC cells

03/12/17

Sulforaphane in broccoli heightens taxane effects against TN disease

10/09/16

Melatonin reduces the viability of both ER+ and ER- BC stem cells

05/23/15

Sulforaphane inhibits HER2+ and triple negative breast cancer

04/18/15

Aspirin reduces growth and self-renewal capacity of BC stem cells

02/22/15

Blueberry and ginger compounds enhance Taxol treatment effects

03/29/13

Blueberry compound inhibits BC stem cell generation and activities

06/13/12

It's too early to regrow breasts using fat stem cells

03/15/12

Black pepper compound suppresses mammary cancer growth and metastasis

03/06/12

Inflammation leads to transformation of normal cells into BC cells

02/16/12

Radiotherapy can convert surviving cancer cells into stem cells

11/18/11

Metformin may increase the effectiveness of radiation treatment

09/21/11

Prenatal exposure to BPA induces precancerous changes in offspring

09/13/11

Some fish oil supplements could interfere with chemotherapy

11/03/10

Chemotherapy resistance is accompanied by more BC stem cells

04/18/10

Broccoli compound sulforaphane reduces BC stem cell survival

Studies

• From dietary lignans to cancer therapy: Integrative systems analysis of enterolactone's molecular targets and signaling pathways in combatting cancer stem cells in triple-negative breast cancer Cite
  Mahajan A, Sharma N, Ulhe A, Patil R, Hegde M, Mali A. From dietary lignans to cancer therapy: Integrative systems analysis of enterolactone's molecular targets and signaling pathways in combatting cancer stem cells in triple-negative breast cancer. Food Bioscience. Elsevier BV; 2024; 58:103732 10.1016/j.fbio.2024.103732
• Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness Cite
  Mathan SV, Singh R, Kim S, Singh SV, Singh RP. Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness. Cancers. MDPI AG; 2024; 16:378 10.3390/cancers16020378
• The role of oncolytic virotherapy and viral oncogenes in the cancer stem cells: a review of virus in cancer stem cells Cite
  Faghihkhorasani A, Dalvand A, Derafsh E, Tavakoli F, Younis NK, Yasamineh S, et al. The role of oncolytic virotherapy and viral oncogenes in the cancer stem cells: a review of virus in cancer stem cells. Cancer Cell International. Springer Science and Business Media LLC; 2023; 23 10.1186/s12935-023-03099-y
• Mycochemicals against Cancer Stem Cells Cite
  Tacchini M, Sacchetti G, Guerrini A, Paganetto G. Mycochemicals against Cancer Stem Cells. Toxins. MDPI AG; 2023; 15:360 10.3390/toxins15060360
• Whole grain metabolite 3,5-dihydroxybenzoic acid is a beneficial nutritional molecule with the feature of a double-edged sword in human health: a critical review and dietary considerations Cite
  Wagner W, Sobierajska K, Pułaski Ł, Stasiak A, Ciszewski WM. Whole grain metabolite 3,5-dihydroxybenzoic acid is a beneficial nutritional molecule with the feature of a double-edged sword in human health: a critical review and dietary considerations. Critical Reviews in Food Science and Nutrition. Informa UK Limited; 2023;:1-19 10.1080/10408398.2023.2203762
• Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells Cite
  Ghanbari-Movahed M, Shafiee S, Burcher JT, Lagoa R, Farzaei MH, Bishayee A. Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells. Metabolites. MDPI AG; 2023; 13:404 10.3390/metabo13030404
• Kaempferol attenuates viability of ex-vivo cultured post-NACT breast tumorexplants through downregulation of p53 induced stemness, inflammation and apoptosis evasion pathways Cite
  Nandi SK, Pradhan A, Das B, Das B, Basu S, Dutta A, et al. Kaempferol attenuates viability of ex-vivo cultured post-NACT breast tumorexplants through downregulation of p53 induced stemness, inflammation and apoptosis evasion pathways. Pathology - Research and Practice. Elsevier BV; 2022;:154029 10.1016/j.prp.2022.154029
• Pomegranate seed extract enhances the inhibitory effect of adipose- derived mesenchymal stem cells on breast cancer cell line in co-culture conditions Cite
  Hashemibeni B, Moradi-Gharibvand N, Setayeshmehr M, Kazemi M, Safaee A, Khorsandi L, et al. Pomegranate seed extract enhances the inhibitory effect of adipose- derived mesenchymal stem cells on breast cancer cell line in co-culture conditions. Research in Pharmaceutical Sciences. Medknow; 2022; 17:372 10.4103/1735-5362.350238
• Lipoic acid blocks autophagic flux and impairs cellular bioenergetics in breast cancer and reduces stemness Cite
  Chakravarti B, Rajput S, Raza S, Rajak S, Tewari A, Gupta P, et al. Lipoic acid blocks autophagic flux and impairs cellular bioenergetics in breast cancer and reduces stemness. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. Elsevier BV; 2022;:166455 10.1016/j.bbadis.2022.166455
• Antioxidant and antiproliferative activities of solvent fractions of broccoli (Brassica oleracea L.) sprout Cite
  Kim JS, Cuong DM, Bae YB, Cho SK. Antioxidant and antiproliferative activities of solvent fractions of broccoli (Brassica oleracea L.) sprout. Applied Biological Chemistry. Springer Science and Business Media LLC; 2022; 65 10.1186/s13765-022-00700-2
• Piperlongumine loaded PLGA nanoparticles inhibit cancer stem-like cells through modulation of STAT3 in mammosphere model of triple negative breast cancer Cite
  Singh P, Sahoo SK. Piperlongumine loaded PLGA nanoparticles inhibit cancer stem-like cells through modulation of STAT3 in mammosphere model of triple negative breast cancer. International Journal of Pharmaceutics. Elsevier BV; 2022; 616:121526 10.1016/j.ijpharm.2022.121526
• Kaempferol and Apigenin suppresses the stemness properties of TNBC cells by modulating Sirtuins Cite
  Sharma A, Sinha S, Keswani H, Shrivastava N. Kaempferol and Apigenin suppresses the stemness properties of TNBC cells by modulating Sirtuins. Molecular Diversity. Springer Science and Business Media LLC; 2022; 10.1007/s11030-022-10384-x
• C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer Cite
  Liu X, Rulina A, Choi MH, Pedersen L, Lepland J, Takle ST, et al. C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer. Nature Communications. Springer Science and Business Media LLC; 2022; 13 10.1038/s41467-021-27734-2
• Breast cancer stem cell population in different molecular subtypes of breast cancer Cite
  Gupta P, Singh V, Kumar S, Das A, Singh G, Bal A. Breast cancer stem cell population in different molecular subtypes of breast cancer. Breast Disease. IOS Press; 2022; 41:199-203. 10.3233/BD-210050
• Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics Cite
  Meerson A, Khatib S, Mahajna J. Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics. International Journal of Molecular Sciences. MDPI AG; 2021; 22:13044 10.3390/ijms222313044
• Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer Cite
  Jaggupilli A, Ly S, Nguyen K, Anand V, Yuan B, El-Dana F, et al. Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer. British Journal of Cancer. Springer Science and Business Media LLC; 2021; 10.1038/s41416-021-01636-y
• Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids Cite
  Luo H, Chen C, Li X, Zhang X, Su C, Liu Y, et al. Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids. STEM CELLS. Wiley; 2021; 10.1002/stem.3452
• Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer Cite
  Malla R, Marni R, Chakraborty A, Kamal MA. Diallyl disulfide and diallyl trisulfide in garlic as novel therapeutic agents to overcome drug resistance in breast cancer. Journal of Pharmaceutical Analysis. Elsevier BV; 2021; 10.1016/j.jpha.2021.11.004
• The telomere complex and the origin of the cancer stem cell Cite
  Torres-Montaner A. The telomere complex and the origin of the cancer stem cell. Biomarker Research. Springer Science and Business Media LLC; 2021; 9 10.1186/s40364-021-00339-z
• Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape Cite
  Salvadori G, Zanardi F, Iannelli F, Lobefaro R, Vernieri C, Longo VD. Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape. Cell Metabolism. Elsevier BV; 2021; 33:2247-2259.e6 10.1016/j.cmet.2021.10.008
• Ferroptosis: Cancer Stem Cells Rely on Iron until “to Die for” It Cite
  Cosialls E, El Hage R, Dos Santos L, Gong C, Mehrpour M, Hamaï A. Ferroptosis: Cancer Stem Cells Rely on Iron until “to Die for” It. Cells. MDPI AG; 2021; 10:2981 10.3390/cells10112981
• Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression Cite
  Jiang G, Tu J, Zhou L, Dong M, Fan J, Chang Z, et al. Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression. Cell Death & Disease. Springer Science and Business Media LLC; 2021; 12 10.1038/s41419-021-04261-y
• Down-regulation of lncRNA MEG3 promotes chronic low dose cadmium exposure-induced cell transformation and cancer stem cell-like property Cite
  Lin H, Rea M, Wang Z, Yang C. Down-regulation of lncRNA MEG3 promotes chronic low dose cadmium exposure-induced cell transformation and cancer stem cell-like property. Toxicology and Applied Pharmacology. Elsevier BV; 2021; 430:115724 10.1016/j.taap.2021.115724
• Rosmarinic acid inhibits stem-like breast cancer through hedgehog and Bcl-2/Bax signaling pathways Cite
  Li H, Ni F, Zhang Y, Chen H, Huang E, Zhuang H, et al. Rosmarinic acid inhibits stem-like breast cancer through hedgehog and Bcl-2/Bax signaling pathways. Pharmacognosy Magazine. Medknow; 2019; 15:600 10.4103/pm.pm_22_19
• Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge Cite
  Bushnell GG, Deshmukh AP, den Hollander P, Luo M, Soundararajan R, Jia D, et al. Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge. npj Breast Cancer. Springer Science and Business Media LLC; 2021; 7 10.1038/s41523-021-00269-x
• Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective Cite
  Winz C, Suh N. Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective. Journal of Cancer Prevention. Korean Society of Cancer Prevention; 2021; 26:18-24 10.15430/jcp.2021.26.1.18
• YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer Cite
  Quinn HM, Vogel R, Popp O, Mertins P, Lan L, Messerschmidt C, et al. YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer. Cancer Research. American Association for Cancer Research (AACR); 2021;:canres.2801.2020 10.1158/0008-5472.can-20-2801
• Tamoxifen induces stem-like phenotypes and multidrug resistance by altering epigenetic regulators in ERα+ breast cancer cells Cite
  Kalyanaraman A, Gnanasampanthapandian D, Shanmughan P, Kishore P, Ramalingam S, Arunachalam R, et al. Tamoxifen induces stem-like phenotypes and multidrug resistance by altering epigenetic regulators in ERα+ breast cancer cells. Stem Cell Investigation. AME Publishing Company; 2020; 7:20-20 10.21037/sci-2020-020
• Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes Cite
  Mavingire N, Campbell P, Wooten J, Aja J, Davis MB, Loaiza-Perez A, et al. Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes. Cancer Letters. Elsevier BV; 2020; 500:64-74 10.1016/j.canlet.2020.12.014
• The Tumor Microenvironment as a Driving Force of Breast Cancer Stem Cell Plasticity Cite
  Fico F, Santamaria-Martínez A. The Tumor Microenvironment as a Driving Force of Breast Cancer Stem Cell Plasticity. Cancers. MDPI AG; 2020; 12:3863 10.3390/cancers12123863
• Breast Cancer Stem Cells: Biomarkers, Identification and Isolation Methods, Regulating Mechanisms, Cellular Origin, and Beyond Cite
  Zhang X, Powell K, Li L. Breast Cancer Stem Cells: Biomarkers, Identification and Isolation Methods, Regulating Mechanisms, Cellular Origin, and Beyond. Cancers. MDPI AG; 2020; 12:3765 10.3390/cancers12123765
• Identification of Potential Therapeutic Target of Naringenin in Breast Cancer Stem Cells Inhibition by Bioinformatics and In Vitro Studies Cite
  Hermawan A, Ikawati M, Istighfari Jenie R, Khumaira A, Putri H, Putri Nurhayati I, et al. Identification of Potential Therapeutic Target of Naringenin in Breast Cancer Stem Cells Inhibition by Bioinformatics and In Vitro Studies. Saudi Pharmaceutical Journal. Elsevier BV; 2020; 10.1016/j.jsps.2020.12.002
• Identification of key genes of hesperidin in inhibition of breast cancer stem cells by functional network analysis Cite
  Hermawan A, Khumaira A, Ikawati M, Putri H, Jenie RI, Angraini SM, et al. Identification of key genes of hesperidin in inhibition of breast cancer stem cells by functional network analysis. Computational Biology and Chemistry. Elsevier BV; 2020; 90:107427 10.1016/j.compbiolchem.2020.107427
• Nitric oxide-targeted therapy inhibits stemness and increases the efficacy of tamoxifen in estrogen receptor-positive breast cancer cells Cite
  López-Sánchez LM, Mena R, Guil-Luna S, Mantrana A, Peñarando J, Toledano-Fonseca M, et al. Nitric oxide-targeted therapy inhibits stemness and increases the efficacy of tamoxifen in estrogen receptor-positive breast cancer cells. Laboratory Investigation. Springer Science and Business Media LLC; 2020; 10.1038/s41374-020-00507-z
• Inhibition of breast cancer stem-like cells by a triterpenoid, ursolic acid, via activation of Wnt antagonist, sFRP4 and suppression of miRNA-499a-5p Cite
  Mandal S, Gamit N, Varier L, Dharmarajan A, Warrier S. Inhibition of breast cancer stem-like cells by a triterpenoid, ursolic acid, via activation of Wnt antagonist, sFRP4 and suppression of miRNA-499a-5p. Life Sciences. Elsevier BV; 2020; 265:118854 10.1016/j.lfs.2020.118854
• Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy Cite
  Silva VR, Neves SP, Santos LdS, Dias RB, Bezerra DP. Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy. Cancers. MDPI AG; 2020; 12:3461 10.3390/cancers12113461
• Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population Cite
  Recouvreux MS, Diaz Bessone MI, Taruselli A, Todaro L, Lago Huvelle MA, Sampayo RG, et al. Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population. Cells. MDPI AG; 2020; 9:2074 10.3390/cells9092074
• 6-Methoxymellein Isolated from Carrot (Daucus carota L.) Targets Breast Cancer Stem Cells by Regulating NF-κB Signaling Cite
  Liu R, Choi HS, Kim S, Kim J, Yun B, Lee D. 6-Methoxymellein Isolated from Carrot (Daucus carota L.) Targets Breast Cancer Stem Cells by Regulating NF-κB Signaling. Molecules. MDPI AG; 2020; 25:4374 10.3390/molecules25194374
• Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway Cite
  Akhtar S, Hourani S, Therachiyil L, Al-Dhfyan A, Agouni A, Zeidan A, et al. Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway. Seminars in Cancer Biology. Elsevier BV; 2020; 10.1016/j.semcancer.2020.08.014
• Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin Cite
  Qin Q, Yang B, Liu Z, Xu L, Song E, Song Y. Polychlorinated biphenyl quinone induced the acquisition of cancer stem cells properties and epithelial-mesenchymal transition through Wnt/β-catenin. Chemosphere. Elsevier BV; 2021; 263:128125 10.1016/j.chemosphere.2020.128125
• Inhibitory effect of melatonin on hypoxia-induced vasculogenic mimicry via suppressing epithelial-mesenchymal transition (EMT) in breast cancer stem cells. Cite
  Maroufi NF, Amiri M, Dizaji BF, Vahedian V, Akbarzadeh M, Roshanravan N, et al. Inhibitory effect of melatonin on hypoxia-induced vasculogenic mimicry via suppressing epithelial-mesenchymal transition (EMT) in breast cancer stem cells.. European Journal of Pharmacology. Elsevier BV; 2020; 881:173282 10.1016/j.ejphar.2020.173282
• Pentadecanoic Acid, an Odd-Chain Fatty Acid, Suppresses the Stemness of MCF-7/SC Human Breast Cancer Stem-Like Cells through JAK2/STAT3 Signaling Cite
  To NB, Nguyen YT, Moon JY, Ediriweera MK, Cho SK. Pentadecanoic Acid, an Odd-Chain Fatty Acid, Suppresses the Stemness of MCF-7/SC Human Breast Cancer Stem-Like Cells through JAK2/STAT3 Signaling. Nutrients. MDPI AG; 2020; 12:1663 10.3390/nu12061663
• Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells Cite
  Arnold KM, Opdenaker LM, Flynn NJ, Appeah DK, Sims-Mourtada J. Radiation induces an inflammatory response that results in STAT3-dependent changes in cellular plasticity and radioresistance of breast cancer stem-like cells. International Journal of Radiation Biology. Informa UK Limited; 2020; 96:434-447 10.1080/09553002.2020.1705423
• Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin Cite
  Nguyen YT, Moon JY, Ediriweera MK, Cho SK. Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin. Cancers. MDPI AG; 2020; 12:268 10.3390/cancers12020268
• Thyroid Hormone Receptor β Inhibits Self-Renewal Capacity of Breast Cancer Stem Cells Cite
  López-Mateo I, Alonso-Merino E, Suarez-Cabrera C, Park JW, Cheng S, Alemany S, et al. Thyroid Hormone Receptor β Inhibits Self-Renewal Capacity of Breast Cancer Stem Cells. Thyroid. Mary Ann Liebert Inc; 2020; 30:116-132 10.1089/thy.2019.0175
• Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin Cite
  Delort L, Bougaret L, Cholet J, Vermerie M, Billard H, Decombat C, et al. Hormonal Therapy Resistance and Breast Cancer: Involvement of Adipocytes and Leptin. Nutrients. MDPI AG; 2019; 11:2839 10.3390/nu11122839
• Abstract 2995: Thymoquinone attenuates breast cancer cell resistance to paclitaxel via targeting tumor associated stem cell population Cite
  Bashmail HA, Alamoudi AA, Hegazy GA, Agabnoor GM, Noorwali A, Al-Abd AM. Abstract 2995: Thymoquinone attenuates breast cancer cell resistance to paclitaxel via targeting tumor associated stem cell population. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2019; 10.1158/1538-7445.am2019-2995
• Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment Cite
  Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, et al. Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. Cellular Oncology. Springer Science and Business Media LLC; 2019; 42:815-828 10.1007/s13402-019-00464-w
• Adipose derived stem cells promote tumor metastasis in breast Cancer cells by stem cell factor inhibition of miR20b Cite
  Xu H, Li W, Luo S, Yuan J, Hao L. Adipose derived stem cells promote tumor metastasis in breast Cancer cells by stem cell factor inhibition of miR20b. Cellular Signalling. Elsevier BV; 2019; 62:109350 10.1016/j.cellsig.2019.109350
• Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome Cite
  Ehmsen S, Pedersen MH, Wang G, Terp MG, Arslanagic A, Hood BL, et al. Increased Cholesterol Biosynthesis Is a Key Characteristic of Breast Cancer Stem Cells Influencing Patient Outcome. Cell Reports. Elsevier BV; 2019; 27:3927-3938.e6 10.1016/j.celrep.2019.05.104
• Anti-metastasis activity of curcumin against breast cancer via the inhibition of stem cell-like properties and EMT Cite
  Hu C, Li M, Guo T, Wang S, Huang W, Yang K, et al. Anti-metastasis activity of curcumin against breast cancer via the inhibition of stem cell-like properties and EMT. Phytomedicine. Elsevier BV; 2018; 58:152740 10.1016/j.phymed.2018.11.001
• Ganoderma lucidum extract (GLE) impairs breast cancer stem cells by targeting the STAT3 pathway Cite
  Rios-Fuller TJ, Ortiz-Soto G, Lacourt-Ventura M, Maldonado-Martinez G, Cubano LA, Schneider RJ, et al. Ganoderma lucidum extract (GLE) impairs breast cancer stem cells by targeting the STAT3 pathway. Oncotarget. Impact Journals, LLC; 2018; 9:35907-35921 10.18632/oncotarget.26294
• Adipose-derived stem cell-mediated paclitaxel delivery inhibits breast cancer growth Cite
  Scioli MG, Artuso S, D'Angelo C, Porru M, D’Amico F, Bielli A, et al. Adipose-derived stem cell-mediated paclitaxel delivery inhibits breast cancer growth. PLOS ONE. Public Library of Science (PLoS); 2018; 13:e0203426 10.1371/journal.pone.0203426
• Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin Cite
  Goto H, Shimono Y, Funakoshi Y, Imamura Y, Toyoda M, Kiyota N, et al. Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin. Oncogene. Springer Science and Business Media LLC; 2018; 38:767-779 10.1038/s41388-018-0477-8
• Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation Cite
  Li S, Zhao Q, Wang B, Yuan S, Wang X, Li K. Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation. Phytotherapy Research. Wiley; 2018; 32:1530-1536 10.1002/ptr.6081
• Resveratrol suppresses migration, invasion and stemness of human breast cancer cells by interfering with tumor-stromal cross-talk Cite
  Suh J, Kim D, Surh Y. Resveratrol suppresses migration, invasion and stemness of human breast cancer cells by interfering with tumor-stromal cross-talk. Archives of Biochemistry and Biophysics. Elsevier BV; 2018; 643:62-71 10.1016/j.abb.2018.02.011
• Chemotherapy Induces Breast Cancer Stemness in Association with Dysregulated Monocytosis Cite
  Liu L, Yang L, Yan W, Zhai J, Pizzo DP, Chu P, et al. Chemotherapy Induces Breast Cancer Stemness in Association with Dysregulated Monocytosis. Clinical Cancer Research. American Association for Cancer Research (AACR); 2018; 24:2370-2382 10.1158/1078-0432.ccr-17-2545
• Is invasion a necessary step for metastases in breast cancer? Cite
  Narod SA, Sopik V. Is invasion a necessary step for metastases in breast cancer?. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2018; 169:9-23 10.1007/s10549-017-4644-3
• Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking Cite
  Sun X, Xu C, Xiao G, Meng J, Wang J, Tang S, et al. Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking. International Journal of Molecular Medicine. Spandidos Publications; 2018; 10.3892/ijmm.2018.3388
• Quercetin suppresses breast cancer stem cells (CD44 + /CD24 − ) by inhibiting the PI3K/Akt/mTOR-signaling pathway Cite
  Li X, Zhou N, Wang J, Liu Z, Wang X, Zhang Q, et al. Quercetin suppresses breast cancer stem cells (CD44 + /CD24 − ) by inhibiting the PI3K/Akt/mTOR-signaling pathway. Life Sciences. Elsevier BV; 2018; 196:56-62 10.1016/j.lfs.2018.01.014
• Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity Cite
  Huang C, Chen Y, Liu H, Yang J, Song X, Zhao J, et al. Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity. Oncotarget. Impact Journals, LLC; 2017; 8:115254-115269 10.18632/oncotarget.23250
• Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis Cite
  Nandy SB, Orozco A, Lopez-Valdez R, Roberts R, Subramani R, Arumugam A, et al. Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis. British Journal of Cancer. Springer Science and Business Media LLC; 2017; 117:1665-1675 10.1038/bjc.2017.335
• Pomegranate Extract Alters Breast Cancer Stem Cell Properties in Association with Inhibition of Epithelial-to-Mesenchymal Transition Cite
  Nallanthighal S, Elmaliki KM, Reliene R. Pomegranate Extract Alters Breast Cancer Stem Cell Properties in Association with Inhibition of Epithelial-to-Mesenchymal Transition. Nutrition and Cancer. Informa UK Limited; 2017; 69:1088-1098 10.1080/01635581.2017.1359318
• The Regulation of Pathways of Inflammation and Resolution in Immune Cells and Cancer Stem Cells by Selenium Cite
  Diwakar BT, Korwar AM, Paulson RF, Prabhu KS. The Regulation of Pathways of Inflammation and Resolution in Immune Cells and Cancer Stem Cells by Selenium. Advances in Cancer Research. Elsevier; 2017;:153-172 10.1016/bs.acr.2017.07.003
• Lineage-Restricted Mammary Stem Cells Sustain the Development, Homeostasis, and Regeneration of the Estrogen Receptor Positive Lineage Cite
  Van Keymeulen A, Fioramonti M, Centonze A, Bouvencourt G, Achouri Y, Blanpain C. Lineage-Restricted Mammary Stem Cells Sustain the Development, Homeostasis, and Regeneration of the Estrogen Receptor Positive Lineage. Cell Reports. Elsevier BV; 2017; 20:1525-1532 10.1016/j.celrep.2017.07.066
• An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells Cite
  Jia D, Li L, Andrew S, Allan D, Li X, Lee J, et al. An autocrine inflammatory forward-feedback loop after chemotherapy withdrawal facilitates the repopulation of drug-resistant breast cancer cells. Cell Death & Disease. Springer Science and Business Media LLC; 2017; 8:e2932-e2932 10.1038/cddis.2017.319
• Abstract 5261: Tocopherols inhibit the estrogen-stimulated expansion of cancer stem cells via down-regulation of OCT4 and NFκB Cite
  Bak MJ. Abstract 5261: Tocopherols inhibit the estrogen-stimulated expansion of cancer stem cells via down-regulation of OCT4 and NFκB. Prevention Research. American Association for Cancer Research; 2017; 10.1158/1538-7445.am2017-5261
• Bisphenol A Induces Sox2 in ER+ Breast Cancer Stem-Like Cells Cite
  Lillo MA, Nichols C, Seagroves TN, Miranda-Carboni GA, Krum SA. Bisphenol A Induces Sox2 in ER+ Breast Cancer Stem-Like Cells. Hormones and Cancer. Springer Science and Business Media LLC; 2017; 8:90-99 10.1007/s12672-017-0286-5
• Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells Cite
  Burnett JP, Lim G, Li Y, Shah RB, Lim R, Paholak HJ, et al. Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells. Cancer Letters. Elsevier BV; 2017; 394:52-64 10.1016/j.canlet.2017.02.023
• Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia Cite
  Carcereri de Prati A, Butturini E, Rigo A, Oppici E, Rossin M, Boriero D, et al. Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia. Journal of Cellular Biochemistry. Wiley; 2017; 118:3237-3248 10.1002/jcb.25972
• Vitamin D compounds inhibit cancer stem-like cells and induce differentiation in triple negative breast cancer Cite
  Shan NL, Wahler J, Lee HJ, Bak MJ, Gupta SD, Maehr H, et al. Vitamin D compounds inhibit cancer stem-like cells and induce differentiation in triple negative breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. Elsevier BV; 2017; 173:122-129 10.1016/j.jsbmb.2016.12.001
• p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors Cite
  Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, et al. p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors. Oncogene. Springer Science and Business Media LLC; 2016; 36:2355-2365 10.1038/onc.2016.396
• Evaluation of Melatonin Effect on Human Breast Cancer Stem Cells Using a Threedimensional Growth Method of Mammospheres Cite
  Lopes JR, Kavagutti MdS, de Medeiros FAF, de Campos Zuccari DAP. Evaluation of Melatonin Effect on Human Breast Cancer Stem Cells Using a Threedimensional Growth Method of Mammospheres. Anti-Cancer Agents in Medicinal Chemistry. Bentham Science Publishers Ltd.; 2017; 17 10.2174/1871520616666160923093229
• Melatonin decreases estrogen receptor binding to estrogen response elements sites on the OCT4 gene in human breast cancer stem cells Cite
  Lopes J, Arnosti D, Trosko JE, Tai M, Zuccari D. Melatonin decreases estrogen receptor binding to estrogen response elements sites on the OCT4 gene in human breast cancer stem cells. Genes & Cancer. Impact Journals, LLC; 2016; 7:209-217 10.18632/genesandcancer.107
• Abstract 5237: Protection of tocopherols against estrogen-induced breast cancer via mechanisms targeting cancer stem cells Cite
  Bak MJ, Das Gupta S, Wahler J, Lee M, Lin Y, Joe Shih W, et al. Abstract 5237: Protection of tocopherols against estrogen-induced breast cancer via mechanisms targeting cancer stem cells. Prevention Research. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-5237
• Abstract 2608: Dietary polyunsaturated fatty acids modulate adipose inflammation and the adipokine secretome to influence mammary stem cell self-renewal Cite
  Esper RM, Hill E, Jiang Y, Aslam N, Simon B, Wicha M, et al. Abstract 2608: Dietary polyunsaturated fatty acids modulate adipose inflammation and the adipokine secretome to influence mammary stem cell self-renewal. Prevention Research. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-2608
• Abstract 2173: Sulforaphane suppresses the growth of triple-negative breast cancer stem cells in vitro and in vivo Cite
  Castro NP, Rangel MC, Merchant AS, Saylor K, Salomon D, Kim Y. Abstract 2173: Sulforaphane suppresses the growth of triple-negative breast cancer stem cells in vitro and in vivo. Cancer Chemistry. American Association for Cancer Research; 2016; 10.1158/1538-7445.am2016-2173
• Therapeutic resistance and cancer recurrence mechanisms: Unfolding the story of tumour coming back Cite
  Esmatabadi MJD, Bakhshinejad B, Motlagh FM, Babashah S, Sadeghizadeh M. Therapeutic resistance and cancer recurrence mechanisms: Unfolding the story of tumour coming back. Journal of Biosciences. Springer Science and Business Media LLC; 2016; 41:497-506 10.1007/s12038-016-9624-y
• Targeting cell death signalling in cancer: minimising ‘Collateral damage’ Cite
  Fox JL, MacFarlane M. Targeting cell death signalling in cancer: minimising ‘Collateral damage’. British Journal of Cancer. Springer Science and Business Media LLC; 2016; 115:5-11 10.1038/bjc.2016.111
• Transcriptomic profiling of curcumin-treated human breast stem cells identifies a role for stearoyl-coa desaturase in breast cancer prevention Cite
  Colacino JA, McDermott SP, Sartor MA, Wicha MS, Rozek LS. Transcriptomic profiling of curcumin-treated human breast stem cells identifies a role for stearoyl-coa desaturase in breast cancer prevention. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2016; 158:29-41 10.1007/s10549-016-3854-4
• COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis Cite
  Majumder M, Xin X, Liu L, Tutunea-Fatan E, Rodriguez-Torres M, Vincent K, et al. COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis. STEM CELLS. Wiley; 2016; 34:2290-2305 10.1002/stem.2426
• Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44+/CD24−/low Stem Cell Phenotype Cite
  Gao X, Sishc BJ, Nelson CB, Hahnfeldt P, Bailey SM, Hlatky L. Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44+/CD24−/low Stem Cell Phenotype. Frontiers in Oncology. Frontiers Media SA; 2016; 6 10.3389/fonc.2016.00138
• Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA Cite
  Zhang C, Samanta D, Lu H, Bullen JW, Zhang H, Chen I, et al. Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA. Proceedings of the National Academy of Sciences. Proceedings of the National Academy of Sciences; 2016; 113:E2047-E2056 10.1073/pnas.1602883113
• The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells Cite
  Stanford EA, Wang Z, Novikov O, Mulas F, Landesman-Bollag E, Monti S, et al. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biology. Springer Science and Business Media LLC; 2016; 14 10.1186/s12915-016-0240-y
• Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines Cite
  Gonçalves NdN, Colombo J, Lopes JR, Gelaleti GB, Moschetta MG, Sonehara NM, et al. Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines. PLOS ONE. Public Library of Science (PLoS); 2016; 11:e0150407 10.1371/journal.pone.0150407
• Cancer stem cells and chemoresistance: The smartest survives the raid Cite
  Zhao J. Cancer stem cells and chemoresistance: The smartest survives the raid. Pharmacology & Therapeutics. Elsevier BV; 2016; 160:145-158 10.1016/j.pharmthera.2016.02.008
• CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells Cite
  Suyama K, Onishi H, Imaizumi A, Shinkai K, Umebayashi M, Kubo M, et al. CD24 suppresses malignant phenotype by downregulation of SHH transcription through STAT1 inhibition in breast cancer cells. Cancer Letters. Elsevier BV; 2016; 374:44-53 10.1016/j.canlet.2015.12.013
• Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism Cite
  LIU Y, ZOU T, WANG S, CHEN H, SU D, FU X, et al. Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism. International Journal of Oncology. Spandidos Publications; 2016; 48:1063-1072 10.3892/ijo.2016.3351
• Effects of surgery on the cancer stem cell niche Cite
  O'Leary D, O'Leary E, Foley N, Cotter T, Wang J, Redmond H. Effects of surgery on the cancer stem cell niche. European Journal of Surgical Oncology (EJSO). Elsevier BV; 2016; 42:319-325 10.1016/j.ejso.2015.12.008
• Synthesis, in vitro, and in vivo evaluation of novel functionalized quaternary ammonium curcuminoids as potential anti-cancer agents Cite
  Solano LN, Nelson GL, Ronayne CT, Lueth EA, Foxley MA, Jonnalagadda SK, et al. Synthesis, in vitro, and in vivo evaluation of novel functionalized quaternary ammonium curcuminoids as potential anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. Elsevier BV; 2015; 25:5777-5780 10.1016/j.bmcl.2015.10.061
• 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death Cite
  Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLOS ONE. Public Library of Science (PLoS); 2015; 10:e0137614 10.1371/journal.pone.0137614
• Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis Cite
  Cook MT, Liang Y, Goyette S, Mafuvadze B, Besch-Williford C, Hyder S. Abstract 4159: Therapeutic effects of luteolin against progestin-dependent breast cancer involves induction of apoptosis, and suppression of both stem-cell-like cells and angiogenesis. Tumor Biology. American Association for Cancer Research; 2015; 10.1158/1538-7445.am2015-4159
• mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells Cite
  Karthik G, Ma R, Lövrot J, Kis LL, Lindh C, Blomquist L, et al. mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells. Cancer Letters. Elsevier BV; 2015; 367:76-87 10.1016/j.canlet.2015.07.017
• Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer. Cite
  Burnett J, Korkaya H, Newman B, Conley S, Connarn J, Sun L, et al. Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer.. Experimental and Molecular Therapeutics. American Association for Cancer Research; 2013; 10.1158/1538-7445.am2013-913
• Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene Cite
  Wu C, Hong B, Ho C, Yen G. Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene. Journal of Agricultural and Food Chemistry. American Chemical Society (ACS); 2015; 63:2432-2441 10.1021/acs.jafc.5b00002
• The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate Cite
  Kim S, Singh SV. The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2015; 149:681-692 10.1007/s10549-015-3279-5
• Silibinin affects tumor cell growth because of reduction of stemness properties and induction of apoptosis in 2D and 3D models of MDA-MB-468 Cite
  Abdollahi P, Ebrahimi M, Motamed N, Samani FS. Silibinin affects tumor cell growth because of reduction of stemness properties and induction of apoptosis in 2D and 3D models of MDA-MB-468. Anti-Cancer Drugs. Ovid Technologies (Wolters Kluwer Health); 2015; 26:487-497 10.1097/cad.0000000000000205
• Chronic Exposure to Combined Carcinogens Enhances Breast Cell Carcinogenesis with Mesenchymal and Stem-Like Cell Properties Cite
  Pluchino LA, Wang HR. Chronic Exposure to Combined Carcinogens Enhances Breast Cell Carcinogenesis with Mesenchymal and Stem-Like Cell Properties. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e108698 10.1371/journal.pone.0108698
• Resveratrol Inhibits Breast Cancer Stem-Like Cells and Induces Autophagy via Suppressing Wnt/β-Catenin Signaling Pathway Cite
  Fu Y, Chang H, Peng X, Bai Q, Yi L, Zhou Y, et al. Resveratrol Inhibits Breast Cancer Stem-Like Cells and Induces Autophagy via Suppressing Wnt/β-Catenin Signaling Pathway. PLoS ONE. Public Library of Science (PLoS); 2014; 9:e102535 10.1371/journal.pone.0102535
• Irradiation of Juvenile, but not Adult, Mammary Gland Increases Stem Cell Self-Renewal and Estrogen Receptor Negative Tumors Cite
  Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruis H, Illa-Bochaca I, Nguyen DH, et al. Irradiation of Juvenile, but not Adult, Mammary Gland Increases Stem Cell Self-Renewal and Estrogen Receptor Negative Tumors. STEM CELLS. Wiley; 2014; 32:649-661 10.1002/stem.1533
• Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo Cite
  Kim S, Sehrawat A, Singh SV. Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo. Cancer Prevention Research. American Association for Cancer Research (AACR); 2013; 6:782-790 10.1158/1940-6207.capr-13-0100
• Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF-κB/microRNA 448 circuit Cite
  Mak K, Wu ATH, Lee W, Chang T, Chiou J, Wang L, et al. Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF-κB/microRNA 448 circuit. Molecular Nutrition & Food Research. Wiley; 2013; 57:1123-1134 10.1002/mnfr.201200549
• Breast Cancer Stem Cell-Like Cells Are More Sensitive to Ionizing Radiation than Non-Stem Cells: Role of ATM Cite
  Kim S, Rhee JG, Song X, Prochownik EV, Spitz DR, Lee YJ. Breast Cancer Stem Cell-Like Cells Are More Sensitive to Ionizing Radiation than Non-Stem Cells: Role of ATM. PLoS ONE. Public Library of Science (PLoS); 2012; 7:e50423 10.1371/journal.pone.0050423
• Diindolilmethane (DIM) selectively inhibits cancer stem cells Cite
  Semov A, Iourtchenco L, Lin Fang L, Shengmin L, Xu Y, Su X, et al. Diindolilmethane (DIM) selectively inhibits cancer stem cells. Biochemical and Biophysical Research Communications. Elsevier BV; 2012; 424:45-51 10.1016/j.bbrc.2012.06.062
• Tumor Angiogenesis as a Target for Dietary Cancer Prevention Cite
  Li WW, Li VW, Hutnik M, Chiou AS. Tumor Angiogenesis as a Target for Dietary Cancer Prevention. Journal of Oncology. Hindawi Limited; 2012; 2012:1-23 10.1155/2012/879623
• CD24−/low stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability Cite
  Bensimon J, Altmeyer-Morel S, Benjelloun H, Chevillard S, Lebeau J. CD24−/low stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability. Oncogene. Springer Science and Business Media LLC; 2012; 32:251-258 10.1038/onc.2012.31
• Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type Cite
  Nguyen D, Oketch-Rabah H, Illa-Bochaca I, Geyer F, Reis-Filho J, Mao J, et al. Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type. Cancer Cell. Elsevier BV; 2011; 19:640-651 10.1016/j.ccr.2011.03.011
• Radiation-Induced Reprogramming of Breast Cancer Cells Cite
  Lagadec C, Vlashi E, Della Donna L, Dekmezian C, Pajonk F. Radiation-Induced Reprogramming of Breast Cancer Cells. STEM CELLS. Wiley; 2012; 30:833-844 10.1002/stem.1058
• Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials Cite
  Early Breast Cancer Trialists' Collaborative Group (EBCTCG) . Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials. The Lancet. Elsevier BV; 2012; 379:432-444 10.1016/s0140-6736(11)61625-5
• Abstract C74: Eradicating cancer stem cells by targeting mTOR pathway with metformin. Cite
  Park HJ, Lee H, Williams B, Song CW. Abstract C74: Eradicating cancer stem cells by targeting mTOR pathway with metformin.. mTOR / PI3-Kinase. American Association for Cancer Research; 2011; 10.1158/1535-7163.targ-11-c74
• Breast-Cancer Adjuvant Therapy with Zoledronic Acid Cite
  Coleman RE, Marshall H, Cameron D, Dodwell D, Burkinshaw R, Keane M, et al. Breast-Cancer Adjuvant Therapy with Zoledronic Acid. New England Journal of Medicine. Massachusetts Medical Society; 2011; 365:1396-1405 10.1056/nejmoa1105195
• Perinatal Exposure to Bisphenol A Increases Adult Mammary Gland Progesterone Response and Cell Number Cite
  Ayyanan A, Laribi O, Schuepbach-Mallepell S, Schrick C, Gutierrez M, Tanos T, et al. Perinatal Exposure to Bisphenol A Increases Adult Mammary Gland Progesterone Response and Cell Number. Molecular Endocrinology. The Endocrine Society; 2011; 25:1915-1923 10.1210/me.2011-1129
• Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids Cite
  Roodhart J, Daenen L, Stigter E, Prins H, Gerrits J, Houthuijzen J, et al. Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids. Cancer Cell. Elsevier BV; 2011; 20:370-383 10.1016/j.ccr.2011.08.010
• Fresh Surgical Specimens Yield Breast Stem/Progenitor Cells and Reveal Their Oncogenic Abnormalities Cite
  Pommier SJ, Hernandez A, Han E, Massimino K, Muller P, Diggs B, et al. Fresh Surgical Specimens Yield Breast Stem/Progenitor Cells and Reveal Their Oncogenic Abnormalities. Annals of Surgical Oncology. Springer Science and Business Media LLC; 2011; 19:527-535 10.1245/s10434-011-1892-z
• Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1 Cite
  Zeng H, Irwin ML, Lu L, Risch H, Mayne S, Mu L, et al. Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2011; 133:127-135 10.1007/s10549-011-1716-7
• The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells Cite
  Menendez . The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells. Oncology Reports. Spandidos Publications; 2010; 25 10.3892/or_00001052
• Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics Cite
  Calcagno AM, Salcido CD, Gillet J, Wu C, Fostel JM, Mumau MD, et al. Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics. JNCI: Journal of the National Cancer Institute. Oxford University Press (OUP); 2010; 102:1637-1652 10.1093/jnci/djq361
• Progesterone induces adult mammary stem cell expansion Cite
  Joshi PA, Jackson HW, Beristain AG, Di Grappa MA, Mote PA, Clarke CL, et al. Progesterone induces adult mammary stem cell expansion. Nature. Springer Science and Business Media LLC; 2010; 465:803-807 10.1038/nature09091
• Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Cite
  Li Y, Zhang T, Korkaya H, Liu S, Lee H, Newman B, et al. Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells. Clinical Cancer Research. American Association for Cancer Research (AACR); 2010; 16:2580-2590 10.1158/1078-0432.ccr-09-2937
• Targeting breast stem cells with the cancer preventive compounds curcumin and piperine Cite
  Kakarala M, Brenner DE, Korkaya H, Cheng C, Tazi K, Ginestier C, et al. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine. Breast Cancer Research and Treatment. Springer Science and Business Media LLC; 2009; 122:777-785 10.1007/s10549-009-0612-x
• Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission Cite
  Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission. Cancer Research. American Association for Cancer Research (AACR); 2009; 69:7507-7511 10.1158/0008-5472.can-09-2994