Tag: p53
p53: A tumor suppressor protein whose activation results either in cell death or DNA repair. Normally, p53 prevents the progression of cells with incorrect numbers of chromosomes toward cancer. However, p53 mutations can endow p53 with new functions that promote, instead of inhibit, cancer formation.Articles
News
- Blood of mice implanted with beef growth promoter zeranol increases breast cell proliferation
- Cholesterol drugs might inhibit tumor formation in some breast cancer patients
- Measles virus may be associated with breast cancer
- Oral contraceptive use at young age increases risk of triple negative breast cancer
- Polycyclic aromatic hydrocarbons increase breast cancer risk partly through p53 mutations
- What are the characteristics of breast cancer with low risk of recurrence?
Studies
- β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation
- Activation of caspase-8 contributes induction of apoptosis in HCT-116 human colon cancer cells by the dietary compound fisetin
- Antiproliferative Effects of Honey and of Its Polyphenols: A Review
- Apigenin augments the growth inhibitory effects of doxorubicin in breast cancer cells derived from African American patients
- Apoptosis-mediated inhibition of human breast cancer cell proliferation by lemon citrus extract
- Associations between Polycyclic Aromatic Hydrocarbon-Related Exposures and p53 Mutations in Breast Tumors
- Canola oil inhibits human breast cancer cell growth by regulating caspase-3 and p53
- Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo
- Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer
- Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy
- Distribution and Biological Activities of the Flavonoid Luteolin
- Early operable primary breast cancer in elderly (over 70) women: Are they biologically different from their younger counterparts?
- Effect of flavonone hesperidin on the apoptosis of human mammary carcinoma cell line MCF-7
- Effect of the Silybin-Phosphatidylcholine Complex (IdB 1016) on the Development of Mammary Tumors in HER-2/neu Transgenic Mice
- Effects of emodin on the gene expression profiling of human breast carcinoma cells
- Exercise Effects on Tumorigenesis in a p53-Deficient Mouse Model of Breast Cancer
- High-risk human papilloma virus infection, tumor pathophenotypes, and BRCA1/2 and TP53 status in juvenile breast cancer
- Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival
- Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro
- Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: involvement of cell line-specific apoptotic mechanisms
- Measles virus antigens in breast cancer
- Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
- Non-steroidal anti-inflammatory drugs (NSAIDs) and breast cancer risk: differences by molecular subtype
- p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression
- Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells
- Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor α gene expression via p38MAPK/CK2 signaling in human breast cancer cells
- Serum Derived from Zeranol-implanted ACI Rats Promotes the Growth of Human Breast Cancer Cells In Vitro
- Single-center experience of male breast cancer: Molecular pathology and potential treatment implications
- Tumor-promoting and tumor-protective effects of high-fat diets on chemically induced mammary cancer in rats
- Tumour characteristics among women with very low-risk breast cancer
- Use of four biomarkers to evaluate the risk of breast cancer subtypes in the women's contraceptive and reproductive experiences study