Tag: isothiocyanates

News

• Brassica compound DIM inhibits breast cancer cell growth synergistically with Taxotere
• Broccoli compound sulforaphane reduces breast cancer stem cell growth and survival
• Cruciferous vegetable compound induces breast cancer cell death
• Cruciferous vegetable consumption linked to reduced risk of cancer
• DIM from broccoli and other brassica vegetables prevents metastasis in mice
• Enhance tamoxifen treatment and reduce tamoxifen resistance with HDAC inhibitors
• Isothiocyanates found in brassica vegetables have genotoxic potential at concentrated doses
• Sulforaphane, a powerful anti-cancer compound, is available from cooked broccoli
• Watercress reduces breast cancer growth by inhibiting angiogenesis

Foods

• broccoli  brussels sprouts  cabbage  cauliflower  greens  horseradish  kale  mustard  papaya  turnips and turnip greens  watercress 

Studies

• Antigenotoxic action of isothiocyanate-containing mustard as determined by two cancer biomarkers in a human intervention trial
• Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells
• Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells
• Benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells is associated with downregulation of urokinase-type plasminogen activator and its receptor
• Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design
• Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype
• Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells
• Cisplatin combination with allyl isothiocyanate, a constituent of cruciferous vegetables, synergistically increases cancer cell death through activation of caspase 3 and downregulation of the antiapoptotic protein Bcl-2 and survivin
• Comparison of Isothiocyanate Metabolite Levels and Histone Deacetylase Activity in Human Subjects Consuming Broccoli Sprouts or Broccoli Supplement
• Comparison of the Effects of Phenethyl Isothiocyanate and Sulforaphane on Gene Expression in Breast Cancer and Normal Mammary Epithelial Cells
• Content determination of benzyl glucosinolate and anti-cancer activity of its hydrolysis product in Carica papaya L.
• Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk
• Cytotoxic effect of achatininh (lectin) from Achatina fulica against a human mammary carcinoma cell line (MCF7)
• Determination of sinigrin, sinalbin, allyl- and benzyl isothiocyanates by RP-HPLC in mustard powder extracts
• Diet and Risk of Ovarian Cancer in the California Teachers Study Cohort
• Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation
• Dietary Organic Isothiocyanates Are Cytotoxic in Human Breast Cancer MCF-7 and Mammary Epithelial MCF-12A Cell Lines
• Effect of dietary allyl isothiocyanate from Brassica vegetables on serum glutathione S-transferase-α concentration
• Effects of the isothiocyanates sulforaphane and erucin on breast cancer and normal human mammary epithelial cells
• Expression profile of CYP19 in human breast cancer cell lines treated with indole-3-carbinol, 3,3'-diindolylmethane, and sulforaphane
• Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption
• Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health
• In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study
• Influence of fermentation conditions of Brassica oleracea L. var. capitata on the volatile glucosinolate hydrolysis compounds of sauerkrauts
• Inhibition of hypoxia inducible factor by phenethyl isothiocyanate
• Involvement of Toxicity as an Early Event in Urinary Bladder Carcinogenesis Induced by Phenethyl Isothiocyanate, Benzyl Isothiocyanate, and Analogues in F344 Rats
• Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells
• Natural isothiocyanates: Genotoxic potential versus chemoprevention
• p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression
• Physiological effects of broccoli consumption
• Plant-derived biomolecules in fermented cabbage
• Polyphenols, isothiocyanates and carotenoid derivatives enhance estrogenic activity in bone cells but inhibit it in breast cancer cells
• Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
• Regulation of estrogen receptor α expression in human breast cancer cells by sulforaphane
• Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines
• Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice
• Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
• Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane
• Urinary Isothiocyanate Levels, Brassica, and Human Breast Cancer