Tag: BRCA1BRCA2
BRCA1 & BRCA2 mutations: Breast cancer susceptibility gene-1 (BRCA1) and breast cancer susceptibility gene-2 (BRCA2). Mutations in these tumor suppressor genes cause carriers to have relatively high lifetime risks of developing breast, ovarian and other cancers.
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- Age-Specific Incidence Rates for Breast Cancer in Carriers of BRCA1 Mutations from Norway
- Annual screening strategies in BRCA1 and BRCA2 gene mutation carriers
- Appendectomy and cancer risk in Jewish BRCA1 and BRCA2 mutation carriers
- Association of BRCA1 Mutations With Occult Primary Ovarian Insufficiency: A Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks
- Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality
- Association of tamoxifen use and reduced risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers
- BRCA1 and BRCA2 Mutation Carriers, Oral Contraceptive Use, and Breast Cancer Before Age 50
- BRCA1 is an essential regulator of heart function and survival following myocardial infarction
- BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells
- BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years
- BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy
- BRCA2 deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure
- Breast and Ovarian Cancer in Relatives of Cancer Patients, with and without BRCA Mutations
- Breast and Ovarian Cancer Risk and Risk Reduction in Jewish BRCA1/2 Mutation Carriers
- Breast cancer cell response to genistein is conditioned by BRCA1 mutations
- Breast cancer incidence after risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers
- Breast cancer patients with lobular cancer more commonly have a father than a mother diagnosed with cancer
- Breast Cancer Prognosis in BRCA1 and BRCA2 Mutation Carriers: An International Prospective Breast Cancer Family Registry Population-Based Cohort Study
- Breast Cancer Risk for Noncarriers of Family-Specific BRCA1 and BRCA2 Mutations: Findings From the Breast Cancer Family Registry
- Breast Cancer Risk in Relation to Alcohol Consumption and BRCA Gene Mutations - A Case-Only Study of Gene-Environment Interaction
- Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2
- Breastfeeding and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers
- Characteristics of double heterozygosity for BRCA1 and BRCA2 germline mutations in Korean breast cancer patients
- Characteristics of Triple-Negative Breast Cancer in Patients With a BRCA1 Mutation: Results From a Population-Based Study of Young Women
- Characterizing benign breast disease in women at high risk for breast cancer
- Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy
- Clinical outcome of triple negative breast cancer in BRCA1 mutation carriers and noncarriers
- Coffee and caffeine intake and breast cancer risk: An updated dose-response meta-analysis of 37 published studies
- Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers
- Comparison of age at natural menopause in BRCA1/2 mutation carriers with a non-clinic-based sample of women in northern California
- Contralateral Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
- Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations
- Does maternal or paternal inheritance of BRCA mutation affect the age of cancer diagnosis?
- Don't forget fallopian tubes! A morphologic and immunohistochemical study about Fallopian tubes with genetic risk (BRCA mutation)
- Earlier age of onset of BRCA mutation-related cancers in subsequent generations
- Early operable primary breast cancer in elderly (over 70) women: Are they biologically different from their younger counterparts?
- Effect of infertility treatment and pregnancy-related hormones on breast cell proliferation in vitro
- Effects of Resveratrol On Triple Negative (ER-, PR-, HER2-) Breast Cancer Cells
- Evaluation of BRCA1 mutations in an unselected patient population with triple-negative breast cancer
- Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK)
- Family history of breast cancer in first-degree relatives and triple-negative breast cancer risk
- Five-year analysis of magnetic resonance imaging as a screening tool in women at hereditary risk of breast cancer
- Genistein inhibits BRCA1 mutant tumor growth through activation of DNA damage checkpoints, cell cycle arrest, and mitotic catastrophe
- Genotypic and phenotypic analysis of male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas
- Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic Mammary Lesions
- High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients
- High-risk human papilloma virus infection, tumor pathophenotypes, and BRCA1/2 and TP53 status in juvenile breast cancer
- Higher prevalence of BRCA2 mutations among Chinese breast cancer patients in a community oncology clinic
- Impact of BRCA1 mutation on survival after early onset breast cancer
- Impact of teenage oral contraceptive use in a population-based series of early-onset breast cancer cases who have undergone BRCA mutation testing
- Impact of X Chromosome Genes in Explaining the Excess Risk of Cancer in Males
- Increased BRCA1 protein in mammary tumours of rats fed marine ω-3 fatty acids
- Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations
- Increased Rates of Chromosome Breakage in BRCA1 Carriers Are Normalized by Oral Selenium Supplementation
- Is risk-reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer beneficial with respect to distant disease free survival and overall survival?
- Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy
- Long-term results of screening with magnetic resonance imaging in women with BRCA mutations
- Loss of BRCA1 leads to an increased sensitivity to Bisphenol A
- Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner
- Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer
- Online Tool to Guide Decisions for BRCA1/2 Mutation Carriers
- Oophorectomy after Menopause and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers?
- Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk
- Oral contraceptives and risk of ovarian and breast cancers in BRCA mutation carriers: a meta-analysis
- Outcome of metastatic breast cancer in selected women with or without deleterious BRCA mutations
- Parent of Origin of BRCA Mutation May Determine Age at Breast Cancer Diagnosis
- Parental origin of mutation and the risk of breast cancer in a prospective study of women with a BRCA1 or BRCA2 mutation
- Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
- Patient and tumor characteristics associated with contralateral breast cancer in a nested population-based case-control study
- Penetrance of breast cancer, ovarian cancer and contralateral breast cancer in BRCA1 and BRCA2 families: high cancer incidence at older age
- Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening
- Phenocopy breast cancer rates in Israeli BRCA1BRCA2 mutation carrier families: is the risk increased in non-carriers?
- Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers
- Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study
- Prevalence of BRCA mutations in an unselected population of triple-negative breast cancer
- Prevalence of BRCA1 and BRCA2 mutations in non-familial breast cancer patients with high risks in Korea: The Korean Hereditary Breast Cancer (KOHBRA) Study
- Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study
- Prospective Multicenter Cohort Study to Refine Management Recommendations for Women at Elevated Familial Risk of Breast Cancer: The EVA Trial
- Proven non-carriers in BRCA families have an earlier age of onset of breast cancer
- Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry
- Response to Neoadjuvant Systemic Therapy for Breast Cancer in BRCA Mutation Carriers and Noncarriers: A Single-Institution Experience
- Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells
- Risk of breast cancer in male BRCA2 carriers
- Risk of pancreatic cancer in breast cancer families from the Breast Cancer Family Registry
- Screening for Founder Mutations in BRCA1 and BRCA2 in Unselected Jewish Women
- Should all BRCA1 mutation carriers with stage I breast cancer receive chemotherapy?
- The CYP1A2 Genotype Modifies the Association Between Coffee Consumption and Breast Cancer Risk Among BRCA1 Mutation Carriers
- The Effectiveness of Cucurbitacin B in BRCA1 Defective Breast Cancer Cells
- The prevalence of BRCA mutations among familial breast cancer patients in Korea: results of the Korean Hereditary Breast Cancer study
- The risk of breast cancer in women with a BRCA1 mutation from north america and poland
- The Spectrum of BRCA1 and BRCA2 mutations in Breast Cancer Patients in the Bahamas