Newsletter September 2016

Mayo Clinic researchers led by Jan van Deursen have made some progress in uncovering the functions of a protein (BubR1) involved in cell division and how it might be used as a target for cancer treatment. One characteristic that various types of cancer cells have in common is an abnormal chromosome number.

BubR1 is designed to ensure proper cell division by helping to regulate chromosome segregation. It prevents the occurrence of an abnormal number by delaying cell division until all chromosomes are successfully attached to the cellular structures that will pull them apart during mitosis. Van Deursen's team used mice with mutant copies of the BubR1 gene to determine which forms of BubR1 can enhance this process and have the potential to be used in cancer treatment.

Below are links to new topics covered last month in our website.

Best wishes,


Below are links to new topics covered last month in our website.

Factors affecting breast cancer risk, treatment and prognosis

Virus related to mouse mammary tumor virus linked to breast cancer development and aggressiveness

Use of calcium channel blockers linked to risk of breast cancer, especially among overweight women

Food, diet & supplements

Whole grains, including brown rice, associated with lower premenopausal breast cancer risk

Quercetin protects heart from Adriamycin but could interfere with treatment effects

Click on reference for the more information on the study described in this month's newsletter.

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