A new study has reported that blueberry extract inhibits metastasis of triple negative breast cancer cells in the laboratory. The authors also elucidate the mechanism of action of blueberry against breast cancer. Blueberry extract was found to reduce cell proliferation in MDA-MB-231 triple negative cancer cells without harming normal breast cells. In addition, blueberry extract reduced the metastatic potential of triple negative breast cancer cells by reducing cell motility. The ability of blueberry to inhibit triple-negative breast tumor growth was also evaluated using MDA-MB-231 xenografts in mice. Tumor weight and proliferation were found to be lower in blueberry-fed mice and cancer cell death was higher compared with mice not receiving blueberry treatment. The authors conclude that blueberry phytochemicals exert an inhibitory effect on the growth and metastatic potential of MDA-MB-231 cells through modulation of the PI3K/AKT/NFkappaB pathway.