walnuts

Walnuts are recommended for breast cancer

Walnuts are a good source of alpha-linolenic acid (an omega-3 fatty acid), as well as numerous phytosterols, polyphenols and carotenoids, and soluble fiber. Walnuts are also a dietary source of selenium, copper, vitamin E and melatonin. Walnuts have the highest total phenolic content, flavonoid content, and antioxidant activity of the nuts commonly consumed in the U.S. Walnut consumption is associated with reduced risks of coronary vascular disease, type 2 diabetes, and thrombosis formation, and has been shown to lower cholesterol. Despite the high caloric and fat content of nuts, adding a moderate amount of nuts to the diet has been shown not to result in weight gain. Walnut extract has been shown to reduce the proliferation of liver cancer and colon cancer cells in a dose-dependent manner. Ellagic acid, a major antioxidant component of walnuts, has been found to inhibit cell growth and induce apoptosis in cervical cancer cells.

Consumption of alpha-linolenic acid is associated with reduced breast cancer risk. Walnuts are the best source of this plant-derived omega-3 fatty acid. Walnut consumption has been shown in several studies to significantly reduce breast tumor incidence and size in laboratory mice. The melatonin in walnuts protects against breast cancer in several ways, including by reducing aromatase activity within the breast, thereby reducing estrogen production.

Walnut oil has a high content of essential fatty acids and we would recommend it. Unrefined walnut oil is made from nuts that are dried and then cold-pressed, preserving its nutrient content. Walnut oil is best used at room temperature (e.g. in salad dressings) since frying with or heating the oil can produce a slight bitterness, as well as destroying some of its antioxidant content.

Below are links to recent studies concerning this food. For a more complete list, including less recent studies, please click on walnuts.

Tags: alphaLinolenicAcid, carotenoid, copper, ellagicAcid, fiber, melatonin, omega3, proanthocyanidins, proliferation, selenium, type2Diabetes, vitaminE, walnut

Walnuts Have Potential for Cancer Prevention and Treatment in Mice Effect of Melatonin on Tumor Growth and Angiogenesis in Xenograft Model of Breast Cancer Juglanones A and B: Two Novel Tetralone Dimers from Walnut Pericarp (Juglans regia) Dietary selenium supplementation modifies breast tumor growth and metastasis Mechanistic Examination of Walnuts in Prevention of Breast Cancer Selenium intake and breast cancer mortality in a cohort of Swedish women Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids Melatonin suppresses aromatase expression and activity in breast cancer associated fibroblasts Melatonin interferes in the desmoplastic reaction in breast cancer by regulating cytokine production Update on the Healthful Lipid Constituents of Commercially Important Tree Nuts A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Mammary Gland Density Predicts the Cancer Inhibitory Activity of the N-3 to N-6 Ratio of Dietary Fat Dietary Walnut Suppressed Mammary Gland Tumorigenesis in the C(3)1 TAg Mouse Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study Intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease Walnuts May Prevent Breast Cancer Antioxidant and antiproliferative activities of common edible nut seeds Suppression of implanted MDA-MB 231 human breast cancer growth in nude mice by dietary walnut The effects of high walnut and cashew nut diets on the antioxidant status of subjects with metabolic syndrome



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