Grapes
are
highly recommended for breast cancer
Grapes contain polyphenols (resveratrol, quercetin, and catechin) that can act as antioxidants, antiangiogenics, and selective estrogen receptor modifiers. Each of these polyphenols have been found to have chemopreventative properties. Grapes also contain lupeol, pterostilbene, and fisetin, which also have been shown to have anti-cancer properties. Green or white grapes have less powerful anticancer properties than red grapes since they contain fewer polyphenols. Note that grape seed oil and grape seed extract are covered in another web page.
Breast cancer-related effects of
eating
grapes
Red grapes and grape seeds are a good source of resveratrol, which has the ability to suppress proliferation of breast cancer cells and promote cell death. Resveratrol also can inhibit aromatase (the synthesis of estrogen from androgens within the body), which is important for reducing growth-stimulatory effects in estrogen-dependent breast cancer. Resveratrol has also been shown to increase the effects of radiation treatment and the chemotherapy drug Taxol (paclitaxel) against breast cancer.
Additional comments
Non-organic (especially imported) grapes must be washed very thoroughly to remove pesticide residue.
Tags: Taxol,
angiogenesis,
aromataseActivity,
fisetin,
flavonoids,
grapes,
naringenin,
paclitaxel,
quercetin,
radiationTreatment,
resveratrol,
taxanes The presence of melatonin in grapevine (Vitis vinifera L.) berry tissues A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro The antiproliferative effects of pterostilbene on breast cancer in vitro are via inhibition of constitutive and leptin-induced Janus kinase/signal transducer and activator of transcription activation Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy Resveratrol, a polyphenol from grapes, increases breast cancer metastasis but can prevent breast cancer progression in combination with other grape polyphenols Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism Naringenin reduces lung metastasis in a breast cancer resection model Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene Resveratrol enhances the sensitivity of doxorubicin-mediated cell proliferation, invasion, and migration in human breast cancer cell lines Effects of Resveratrol On Triple Negative (ER-, PR-, HER2-) Breast Cancer Cells Resveratrol inhibits migration and invasion of human breast-cancer cells Combined Resveratrol, Quercetin, and Catechin Treatment Reduces Breast Tumor Growth in a Nude Mouse Model Resveratrol Imparts Photoprotection of Normal Cells and Enhances the Efficacy of Radiation Therapy in Cancer Cells Comparison of Antioxidant Potency of Commonly Consumed Polyphenol-Rich Beverages in the United States Anthocyanin-rich berry extracts and epigallocatechin gallate reduce the enhanced invasiveness of estrogen-negative human breast carcinoma cells elicited by serum Fruits, vegetables, soy foods and breast cancer in pre- and postmenopausal Korean women: a case-control study Naringenin inhibits cell growth and migration in human breast cancer cell lines Mammary cancer chemoprevention with the polyphenol resveratrol Quercetin is bioavailable from a single ingestion of grape juice Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial Breast cancer prevention with grape seed phytochemicals Naringenin Inhibits Glucose Uptake in MCF-7 Breast Cancer Cells: A Mechanism for Impaired Cellular Proliferation