Cranberries
are
recommended for breast cancer
Cranberries contain among the highest concentration of antioxidants per serving size of all fruits. They are a good source of phytochemicals that include flavonol glycosides, anthocyanins, proanthocyanidins, resveratrol, and organic and phenolic acids. Cranberries are also a good dietary source of the lignan enterolactone.
Breast cancer-related effects of
eating
cranberries
Cranberries have been shown to have antiproliferative activity against cancer in vitro and in vivo and to induce apoptosis. When fed to mice bearing human breast cancer cells, cranberry presscake (the material remaining after squeezing juice from the berries) has been shown to decrease the growth and metastasis of the tumors.
Cranberries are a good source of resveratrol, which has been shown to increase the effects of radiation treatment, aromatase inhibitors and the chemotherapy drug Taxol (paclitaxel) against breast cancer.
Additional comments
Drinking large volumes of cranberry juice can interfere with warfarin (coumadin) therapy. Cranberry juice and cranberry tablets have been shown to increase the risk of calcium oxalate and uric acid kidney stone formation. Lingonberries are a close relative of cranberries.
Tags: Taxol,
anthocyanin,
aromataseActivity,
aromataseInhibitors,
chemotherapy,
cranberries,
enterolactone,
lignan,
paclitaxel,
proanthocyanidins,
radiationTreatment,
resveratrol Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort study A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells Cold-field fruit extracts exert different antioxidant and antiproliferative activities in vitro Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and HER2 receptor status Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene Identification of Flavonoid and Phenolic Antioxidants in Black Currants, Blueberries, Raspberries, Red Currants, and Cranberries Anticancer activities of cranberry phytochemicals: An update Cranberry proanthocyanidins are cytotoxic to human cancer cells and sensitize platinum-resistant ovarian cancer cells to paraplatin Comparison of Antioxidant Potency of Commonly Consumed Polyphenol-Rich Beverages in the United States Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry Extracts Inhibit Growth and Stimulate Apoptosis of Human Cancer Cells In Vitro In vivo inhibition of growth of human tumor lines by flavonoid fractions from cranberry extract Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines