canola oil

Canola oil is recommended for breast cancer

The canola plant was developed in Canada during the 1970s using conventional selective breeding and hybrid propagation techniques (i.e., not by genetic modification) from turnip rapeseed, black mustard, and leaf mustard. Rapeseed is high in erucic acid, an unhealthy fatty acid, but the canola plant was developed to minimize this component. Canola oil is made from the pressed seed of the canola plant. Canola oil is low in saturated fat and has a high monounsaturated fat content. It contains oleic acid, linoleic acid and alpha-linolenic acid; the oil is a good source of non-marine omega-3 fatty acids. Canola oil is also a dietary source of vitamin E and vitamin K.

Canola oil has anti-inflammatory and antioxidant properties. In one study, consumption of canola oil was found to lower LDL-cholesterol and improve endothelial function in subjects with peripheral arterial occlusive disease, indicating that canola oil might provide cardiovascular protection. Canola oil was shown to prevent diabetic renal injury in diabetic rates in another study. Canola meal (which is left over from the seeds after the oil has been extracted) has been shown to reduce the tumor incidence and volume of both melanoma and colon cancer in mice.

Canola oil has been shown to inhibit growth and induce apoptosis in both estrogen positive (ER+) and estrogen negative (ER-) human breast cancer cells. Female mammary gland cancer-prone rats consuming canola oil during pregnancy have been found to produce offspring with lower tumor numbers, lower tumor volume and lower percentage of mice with tumors than the offspring of mothers on a diet with equivalent amounts of corn oil. Several studies have found that higher omega-3/omega-6 fatty acid ratios are associated with reduced risk of breast cancer; using canola oil would tend to improve the ratio for most women. A 2008 San Francisco population study found that women cooking mainly with olive/canola oil have a lower risk of breast cancer than those cooking with vegetable/corn oil or hydrogenated fats.

Frying with canola oil (especially deep frying or wok frying) has been shown to release carcinogenic polycyclic aromatic hydrocarbons in the cooking oil smoke and fumes (this is true of soybean oil, corn oil, peanut oil, and sunflower oil as well). Breathing such fumes should be avoided since this has been associated with increased risk of lung cancer in several population studies.

While the canola plant was developed using conventional methods, the majority of current canola production comes from genetically modified plants developed for their resistance to herbicides. Organic canola oil is available for those concerned about consuming genetically modified foods.

Possibly because of its connection with rapeseed oil, canola oil has been the subject of many alarming negative (and false) health-related claims, especially on the internet. As mentioned above, rapeseed oil is high in erucic acid (30 to 60 percent) and should be avoided (canola oil contains between 0.3 and 1.2 percent erucic acid, an acceptable amount). Rapeseed oil normally is not sold in U.S. supermarkets but it can be found as an ingredient in some processed foods such as commercial peanut butter. Be aware that in Europe, canola oil is referred to as rape oil or rapeseed oil but it is, in fact, canola oil.

Note that while we are continually searching for new evidence specifically concerning this food, there is not much interest in it among breast cancer researchers, so few studies are available.

Tags: ER+, ER-, PAHs, canolaOil, cardiovascular, cornOil, inflammation, linoleicAcid, mustard, olive, omega3, omega6, peanutOil, pregnancy, prenatalExposure, soybeanOil, sunflowerOil

Maternal consumption of omega 3 fatty acids to reduce breast cancer risk in offspring Mammary Gland Density Predicts the Cancer Inhibitory Activity of the N-3 to N-6 Ratio of Dietary Fat Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring Canola oil inhibits human breast cancer cell growth by regulating caspase-3 and p53 Dietary fat, cooking fat, and breast cancer risk in a multiethnic population Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort Effects of the olive, extra virgin olive and canola oils on cisplatin-induced clastogenesis in Wistar rats N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France



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