Buckwheat is recommended for breast cancer

Buckwheat (Fagopyrum esculentum Moench) is rich in phytochemicals, including rutin, isoquercitrin, quercetin, catechin, myricetin and various anthocyanins. Buckwheat is also a dietary source of vitamin E, vitamin B6, zinc, copper, selenium, and manganese. Components of buckwheat have been found to have antioxidant, anticarcinogenic, antimutagenic, and antifungal properties. Consumption of buckwheat has been shown to reduce gut transit time compared to consumption of white rice, resulting in lower levels of triglycerides, total cholesterol and LDL cholesterol. Consuming buckwheat may also reduce gallstone formation, reduce inflammation and contribute to blood sugar control. One animal study found that germinated buckwheat had potent anti-fatty liver activities.

A component of buckwheat has been shown to reduce proliferation of multiple myeloma cells. Rutin, a major active component of buckwheat, has been found to have anti-angiogenic activity against melanoma in mice, reducing the number of tumor-directed capillaries formed. Rutin also was found to inhibit the proliferation, migration and capillary-like tube formation of human endothelial cells.

An extract of buckwheat hulls has been shown to have cytotoxic effects in human breast, liver and stomach cancer cells. A peptide of buckwheat seeds has been found to inhibit proliferation of liver and breast cancer cells, as well as leukemia cells. Tartary buckwheat (similar to buckwheat) has been found to have antiproliferative effects in human breast cancer cells. Buckwheat also has been shown to inhibit carcinogen-induced mammary tumors in laboratory rats by lowering circulating estrogen.

Buckwheat honey has been found to be a better source of antioxidants than lighter-colored honeys. Japanese soba noodles are made from buckwheat flour.

Tartary buckwheat (Fagopyrum tataricum Gaertn.) is a type of buckwheat regularly consumed in China and parts of India. It has a phytochemical profile similar to common buckwheat, with somewhat more rutin and quercetin.

Below are links to recent studies concerning this food. For a list of studies that includes older research, please click on buckwheat.

Tags: anthocyanins, buckwheat, enterolactone, inflammation, lignan, proliferation, vitaminB6

Effects of selenium compounds on proliferation and epigenetic marks of breast cancer cells Dietary selenium supplementation modifies breast tumor growth and metastasis Bio-guided fraction of antioxidant activity of ethanol extract from tartary buckwheat bran Evaluation of Flavonoid Contents and Antioxidant Capacity of the Aerial Parts of Common and Tartary Buckwheat Plants Bioactive compounds in functional buckwheat food The Effect of Quercetin On Doxorubicin Cytotoxicity in Human Breast Cancer Cells Selenium intake and breast cancer mortality in a cohort of Swedish women Effect of whole grains on markers of subclinical inflammation Reduction of rutin loss in buckwheat noodles and their physicochemical characterisation Anti-infection effects of buckwheat flavonoid extracts (BWFEs) from germinated sprouts Toward a novel understanding of buckwheat self-defensive strategies during seed germination and preliminary investigation on the potential pharmacological application of its malting products Phenolics Content and Antioxidant Activity of Tartary Buckwheat from Different Locations Antioxidative and Anti-Glycation Activity of Buckwheat Hull Tea Infusion Antioxidant activity of commercial buckwheat flours and their free and bound phenolic compositions Phenolic profile and antioxidant properties of Polish honeys Inhibitory Effect of Flavonoids from Tartary Buckwheat Sprouts on Proliferation of Human Breast Cancer Cells Anti-infection effects of buckwheat flavonoid extracts(BWFEs) from germinated sprouts Anti-Tumor Activity of a Novel Protein Obtained from Tartary Buckwheat Evaluation of the mutagenicity and antimutagenicity of extracts from oat, buckwheat and wheat bran in the Salmonella/microsome assay The Contribution of Polyphenols to Antioxidative Activity in Common Buckwheat and Tartary Buckwheat Grain Purification and characterization of the antitumor protein from Chinese tartary buckwheat (Fagopyrum tataricum Gaertn.) water-soluble extracts

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