buckwheat

Buckwheat is recommended for breast cancer

Buckwheat (Fagopyrum esculentum Moench) is rich in phytochemicals, including rutin, isoquercitrin, quercetin, catechin, myricetin and various anthocyanins. Buckwheat is also a dietary source of vitamin E, zinc, copper, selenium, and manganese. Components of buckwheat have been found to have antioxidant, anticarcinogenic, antimutagenic, and antifungal properties. Consumption of buckwheat has been shown to reduce gut transit time compared to consumption of white rice, resulting in lower levels of triglycerides, total cholesterol and LDL cholesterol. Consuming buckwheat may also reduce gallstone formation, reduce colon inflammation and contribute to blood sugar control. One animal study found that germinated buckwheat had potent anti-fatty liver activities. A component of buckwheat has been shown to reduce proliferation of multiple myeloma cells. Rutin, a major active component of buckwheat, has been found to have anti-angiogenic activity against melanoma in mice, reducing the number of tumor-directed capillaries formed. Rutin also was found to inhibit the proliferation, migration and capillary-like tube formation of human endothelial cells.

An extract of buckwheat hulls has been shown to have cytotoxic effects in human breast, liver and stomach cancer cells. A peptide of buckwheat seeds has been found to inhibit proliferation of liver and breast cancer cells, as well as leukemia cells. Tartary buckwheat (similar to buckwheat) has been found to have antiproliferative effects in human breast cancer cells. Buckwheat also has been shown to inhibit carcinogen-induced mammary tumors in laboratory rats by lowering circulating estrogen.

Buckwheat honey has been found to be a better source of antioxidants than lighter-colored honeys. Japanese soba noodles are made from buckwheat flour.

Tartary buckwheat (Fagopyrum tataricum Gaertn.) is a type of buckwheat regularly consumed in China and parts of India. It has a phytochemical profile similar to common buckwheat, with somewhat more rutin and quercetin.

Note that while we are continually searching for new evidence concerning this food, there is not much interest in it among breast cancer researchers so few recent studies are available.

Tags: ER+, ER+/PR+, Indian, Japanese, anthocyanin, antifungal, buckwheat, copper, enterolactone, honey, hormoneReceptorPositive, inflammation, lignan, proliferation

Anti-infection effects of buckwheat flavonoid extracts (BWFEs) from germinated sprouts Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort study Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and HER2 receptor status Evaluation of the mutagenicity and antimutagenicity of extracts from oat, buckwheat and wheat bran in the Salmonella/microsome assay Purification and characterization of the antitumor protein from Chinese tartary buckwheat (Fagopyrum tataricum Gaertn.) water-soluble extracts A relatively stable antifungal peptide from buckwheat seeds with antiproliferative activity toward cancer cells Antiangiogenic Effect of Rutin and its Regulatory Effect on the Production of VEGF, IL-1β and TNF-α in Tumor Associated Macrophages Consumption of a Buckwheat Protein Extract Retards 7,12-Dimethylbenz[α] anthracene-Induced Mammary Carcinogenesis in Rats



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