highly recommended for breast cancer
Blueberries rank among the highest of all fruits and vegetables in the capacity to destroy free radicals. Blueberries contain caffeic acid, catechin, chlorogenic acid, epicatechin, ferulic acid, gallic acid, kaempferol, myricetin, naringenin, p-coumaric acid, p-hydroxybenzoic acid, pterostilbene, resveratrol, quercetin, and ursolic acid, most of which have been reported to have anti-cancer properties.
Breast cancer-related effects of
Blueberries have been found to inhibit mammary cancer cell proliferation in mice and rats, as well as inhibiting cultured cancer cell growth in the laboratory and blood vessel tumors in rats. Pterostilbene has been shown to inhibit obesity-related breast cancer growth and proliferation in the laboratory and to have additive treatment effects when combined with tamoxifen in estrogen receptor positive (ER+) breast cancer cells. Pterostilbene also has been shown to reduce the formation of breast cancer stem cells and inhibit their metastatic activities.
Blueberries are a good source of resveratrol, which has been shown to increase the effects of radiation, aromatase inhibitors and the chemotherapy drug Taxol (paclitaxel) against breast cancer.
The antioxidant properties of blueberries have been shown to be reduced when eaten with milk, suggesting that the best way to gain maximum benefits from blueberries and other fruits eaten for their polyphenol content is to consume them either one hour before or two hours after protein is consumed.
Non-organic blueberries must be washed very thoroughly to remove pesticide residue as much as possible.
Bilberries, which grow wild in much of northern Europe, are closely related to blueberries. They are valued for their high flavonoid content.
Under the list of tags below are links to recent studies concerning this food. For a more complete list of studies, please click on blueberries.
Selected breast cancer studies
Chemopreventive and therapeutic activity of dietary blueberry against estrogen-mediated breast cancer
Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin
Anticancer effects of bioactive berry compounds
Proteomic Profiling Reveals That Resveratrol Inhibits HSP27 Expression and Sensitizes Breast Cancer Cells to Doxorubicin Therapy
Ursolic acid promotes cancer cell death by inducing Atg5-dependent autophagy
Cytotoxicity and apoptosis induction in human breast adenocarcinoma MCF-7 cells by (+)-cyanidan-3-ol
Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF-κB/microRNA 448 circuit
Intake of specific fruits and vegetables in relation to risk of estrogen receptor-negative breast cancer among postmenopausal women
Anti-estrogenic activity of a human resveratrol metabolite
Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase
Resveratrol activates the histone H2B ubiquitin ligase, RNF20, in MDA-MB-231 breast cancer cells
Invadopodia-associated proteins blockade as a novel mechanism for 6-shogaol and pterostilbene to reduce breast cancer cell motility and invasi
Triterpenoid Content of Berries and Leaves of Bilberry Vaccinium myrtillus from Finland and Poland
Cytotoxic Effect of Natural trans-Resveratrol Obtained from Elicited Vitis vinifera Cell Cultures on Three Cancer Cell Lines
Resveratrol induces downregulation of DNA repair genes in MCF-7 human breast cancer cells
Inhibition of estrogen-mediated mammary tumorigenesis by blueberry and black raspberry
Effects of resveratrol on paclitaxel-sensitive and -resistant triple negative breast cancer cells
Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer
Influence of Berry-Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention
Repression of Mammosphere Formation of Human Breast Cancer Cells by Soy Isoflavone Genistein and Blueberry Polyphenolic Acids
Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro
A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis