bell peppers

Bell peppers are recommended for breast cancer

Bell peppers (Capsicum annuum), which are the predominant type of sweet peppers consumed in the U.S., come in a variety of colors, most commonly, green, red and yellow. Bell peppers are excellent dietary sources of vitamin C and vitamin A and also contain some B vitamins. Bell peppers have been shown to have anti-inflammatory, antioxidant, and antimutagenic properties and may help lower cholesterol levels. Bell peppers contain several substances with suspected or demonstrated cancer fighting properties, including beta-carotene and other carotenoids, lupeol, luteolin, quercetin, apigenin, capsiate, catechin, and various glycolipids. Red bell peppers also contain lycopene. Bell pepper consumption has been found to be associated with lower risk of liver and prostate cancer, as well as brain gliomas in women. Hot peppers are covered in another web page.

Apigenin, a flavonoid component of bell peppers, has been shown to exhibit potent growth-inhibitory effects in HER2/neu-overexpressing breast cancer cells. Several Korean studies have found an association between bell pepper consumption and lower incidence of breast cancer. On the other hand, no significant inverse association of breast cancer with intake of green peppers was found in a 2004 study based on the Nurses Health Study II cohort.

Green bell peppers have a higher phenolic content than red bell peppers, whereas red bell peppers (which are the same fruit, but further along in ripening) have higher vitamin C and carotenoid contents. The pimento stuffing found in some olives and paprika are both typically prepared from sweet peppers such as red bell peppers.

Non-organic bell peppers must be washed very thoroughly to remove pesticide residue as much as possible.

Tags: Korean, angiogenesis, apigenin, bellPeppers, betaCarotene, carotenoids, flavone, flavonoids, hotPeppers, inflammation, luteolin, lycopene, olive, paprika, vitaminA, vitaminC

Carotenoid intakes and risk of breast cancer defined by estrogen receptor and progesterone receptor status: a pooled analysis of 18 prospective cohort studies Synergistic Effects of Apigenin and Paclitaxel on Apoptosis of Cancer Cells Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study The flavonoid luteolin induces apoptotic cell death through AIF nuclear translocation mediated by activation of ERK and p38 in human breast cancer cell lines Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7 Apigenin prevents development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats Flavonoids, Proanthocyanidins, and Cancer Risk: A Network of Case-Control Studies From Italy Circulating Carotenoids, Mammographic Density, and Subsequent Risk of Breast Cancer Capsiate, a Nonpungent Capsaicin-Like Compound, Inhibits Angiogenesis and Vascular Permeability via a Direct Inhibition of Src Kinase Activity Comparisons of food intake between breast cancer patients and controls in Korean women Fruits, vegetables, soy foods and breast cancer in pre- and postmenopausal Korean women: a case-control study Micellar oleic and eicosapentaenoic acid but not linoleic acid influences the β-carotene uptake and its cleavage into retinol in rats Dietary flavonols and flavonol-rich foods intake and the risk of breast cancer Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway



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