Apples
are
recommended for breast cancer
Best varieties: Apples with red, rosy or red streaked peels. Eat the peel.
Breast cancer-related effects of
eating
apples
Like pears, apples are a member of the Rosaceae family. One study found that the consumption of apples was inversely related to the risk of breast cancer when the results were adjusted for factors such as age, education, body mass index, alcohol consumption, total energy intake, vegetable consumption and physical activity. Apples have been shown to shrink the size of mammary tumors in rats and to induce breast cancer cell apoptosis. Apple peel contains chemicals that may be important for this effect. Red apples have more antioxidant and antiproliferative phytochemicals than green or yellow apples.
Additional comments
The apple flavonoid phloretin has been shown to increase the anti-cancer effects of the chemotherapy drug Taxol (paclitaxel).
Organic U.S. apples are the best choice. Non-organic apples must be washed very thoroughly to remove pesticide residue. Apple juice is not particularly beneficial compared to raw apples, however cloudy apple juice has more antioxidants than clear apple juice. There have been reports of meaningful levels of arsenic in apple juice produced from apples grown in countries that use certian pesticides no longer approved for use in the U.S.
Tags: Taxol,
apples,
chemotherapy,
taxanes Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells Flavonoids, Proanthocyanidins, and Cancer Risk: A Network of Case-Control Studies From Italy Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human hep G2 cells Fresh Apples Suppress Mammary Carcinogenesis and Proliferative Activity and Induce Apoptosis in Mammary Tumors of the Sprague Dawley Rat Apple Phytochemical Extracts Inhibit Proliferation of Estrogen-Dependent and Estrogen-Independent Human Breast Cancer Cells through Cell Cycle Modulation Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3 Triterpenoids Isolated from Apple Peels Have Potent Antiproliferative Activity and May Be Partially Responsible for Apple's Anticancer Activity Effect of Selected Phytochemicals and Apple Extracts on NF-κB Activation in Human Breast Cancer MCF-7 Cells Does an apple a day keep the oncologist away? Dietary flavonols and flavonol-rich foods intake and the risk of breast cancer Polyphenolic Profiles in Eight Apple Cultivars Using High-Performance Liquid Chromatography